A grand building with a dome and columns, surrounded by well-maintained hedges and a clear blue sky.

Luxury Hotels & Resorts in Tenderloin from AU$128

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Tenderloin Luxury Hotels

Our top choices for Tenderloin luxury hotels

A modern hotel room with a bed, a desk with a chair, a flat-screen TV, and a sliding door leading to a bathroom.

1. Hotel EPIK

Hotel EPIK
4.0 star property
Tenderloin
7.2 out of 10, Good, (812 reviews)
"Very safe and clean place to stay"
United States
Cary
The price is AU$154
includes taxes & fees
29 Nov - 30 Nov
Hotel EPIK
A modern interior with a fireplace, sofas, a coffee table, and a bookshelf.

2. Grand Hyatt San Francisco

Grand Hyatt San Francisco
4.0 star property
Union Square, 0.8 km from Tenderloin
9.0 out of 10, Wonderful, (1,058 reviews)
"Love the location and the hotel entry and everywhere else was clean!"
United States
Kenneth
The price is AU$340
includes taxes & fees
20 Nov - 21 Nov
Grand Hyatt San Francisco
A rooftop terrace with a fire pit, seating, and a view of the city skyline at dusk.

3. San Francisco Proper Hotel

San Francisco Proper Hotel
4.5 star property
Downtown San Francisco, 0.5 km from Tenderloin
8.8 out of 10, Excellent, (916 reviews)
"Boutique Hotel with great restaurants and atmosphere. Highly recommend."
United States
Chris
The price is AU$306
includes taxes & fees
29 Nov - 30 Nov
San Francisco Proper Hotel
A modern hotel room with a grey sofa, a dining table, a TV, and a large window with curtains.

4. The Clift Royal Sonesta San Francisco

The Clift Royal Sonesta San Francisco
4.0 star property
0.4 km from Tenderloin
9.2 out of 10, Wonderful, (1,548 reviews)
"Great trip…pic of view from our room!!!"
United States
Edward
The price is AU$330
includes taxes & fees
20 Nov - 21 Nov
The Clift Royal Sonesta San Francisco
A high-rise room with a city view, a sofa, two chairs, a small table, and a patterned rug.

5. Hilton San Francisco Union Square

Hilton San Francisco Union Square
4.0 star property
Union Square, 0.4 km from Tenderloin
8.6 out of 10, Excellent, (1,896 reviews)
"Great stay!"
United States
Emily
The price is AU$246
includes taxes & fees
24 Nov - 25 Nov
Hilton San Francisco Union Square
A rooftop terrace with a city skyline, a fountain, and outdoor seating.

6. Fairmont San Francisco

Fairmont San Francisco
5.0 star property
Nob Hill, 0.9 km from Tenderloin
9.2 out of 10, Wonderful, (1,627 reviews)
"I had a great stay"
United States
Monique
The price is AU$401
includes taxes & fees
22 Nov - 23 Nov
Fairmont San Francisco
A historic building with ornate architecture, a red carpet entrance, and a sign indicating it is a hotel.

7. Hotel Adagio, Autograph Collection

Hotel Adagio, Autograph Collection
4.0 star property
0.3 km from Tenderloin
8.6 out of 10, Excellent, (1,000 reviews)
"Easy check in. Clean room. Great location"
United States
Tracy
The price is AU$265
includes taxes & fees
29 Nov - 30 Nov
Hotel Adagio, Autograph Collection
A high-rise hotel with multiple floors, large windows, and a well-lit facade.

8. The Westin St. Francis San Francisco on Union Square

The Westin St. Francis San Francisco on Union Square
4.5 star property
0.6 km from Tenderloin
8.8 out of 10, Excellent, (2,132 reviews)
"Loved this hotel Beautiful bar and restaurant Amazing decor"
United States
Sandra
The price is AU$403
includes taxes & fees
20 Nov - 21 Nov
The Westin St. Francis San Francisco on Union Square
An indoor swimming pool with multiple lounge chairs and a high ceiling with skylights.

9. Hotel Nikko San Francisco

Hotel Nikko San Francisco
4.5 star property
Union Square, 0.5 km from Tenderloin
9.4 out of 10, Exceptional, (3,202 reviews)
"Clean rooms, helpful staff, good food .really enjoyed my stay here"
United States
Jessica
The price is AU$368
includes taxes & fees
21 Nov - 22 Nov
Hotel Nikko San Francisco
A rooftop terrace with potted plants, a wooden bench, and wicker pendant lights.

10. Timbri Hotel San Francisco, Curio Collection by Hilton

Timbri Hotel San Francisco, Curio Collection by Hilton
4.0 star property
Union Square, 0.4 km from Tenderloin
8.6 out of 10, Excellent, (1,084 reviews)
"We enjoyed our room and wished we would have checked out the bar as well as breakfast. Friendly staff as well! I would absolutely stay here again!"
United States
Kristine
The price is AU$264
includes taxes & fees
12 Dec - 13 Dec
Timbri Hotel San Francisco, Curio Collection by Hilton
A hotel with a 'NO RESORT FEES' sign, a restaurant, and a cigar store.

11. Marines Memorial Club & Hotel

Marines Memorial Club & Hotel
4.0 star property
0.6 km from Tenderloin
9.6 out of 10, Exceptional, (266 reviews)
"Excellent place to stay and great location!"
United States
Heather
The price is AU$255
includes taxes & fees
20 Nov - 21 Nov
Marines Memorial Club & Hotel
A modern hotel room with a sectional sofa, a patterned armchair, a glass coffee table, and a flat-screen TV.

12. JW Marriott San Francisco Union Square

JW Marriott San Francisco Union Square
4.5 star property
0.5 km from Tenderloin
9.0 out of 10, Wonderful, (1,000 reviews)
"The room was beautiful and the hotel was gorgeous"
United States
Pamela
The price is AU$395
includes taxes & fees
22 Nov - 23 Nov
JW Marriott San Francisco Union Square
A hotel lobby with a grand ceiling, marble flooring, and ornate wall decorations.

13. Hotel Spero, Vignette Collection by IHG

Hotel Spero, Vignette Collection by IHG
4.0 star property
0.3 km from Tenderloin
8.6 out of 10, Excellent, (1,153 reviews)
"Super nice staff, clean and cozy"
United States
Sasha
The price is AU$245
includes taxes & fees
21 Nov - 22 Nov
Hotel Spero, Vignette Collection by IHG
A spacious lobby with modern seating, a large abstract sculpture, and a high ceiling with linear lighting.

14. Hyatt Regency San Francisco

Hyatt Regency San Francisco
4.0 star property
Financial District, 2 km from Tenderloin
9.4 out of 10, Exceptional, (2,573 reviews)
"Great stay!"
United States
Joceline
The price is AU$354
includes taxes & fees
13 Nov - 14 Nov
Hyatt Regency San Francisco
A hotel with a modern design, featuring a prominent 'PARC 55' sign, multiple floors, and a corner location with a visible street view.

15. Parc 55 San Francisco - A Hilton Hotel

Parc 55 San Francisco - A Hilton Hotel
4.0 star property
Union Square, 0.5 km from Tenderloin
8.8 out of 10, Excellent, (1,736 reviews)
"Great stay"
United States
Joseph
The price is AU$250
includes taxes & fees
29 Nov - 30 Nov
Parc 55 San Francisco - A Hilton Hotel
A modern living room with a sofa, two armchairs, a coffee table, and a fireplace.

16. InterContinental San Francisco by IHG

InterContinental San Francisco by IHG
4.0 star property
South of Market, 0.9 km from Tenderloin
9.2 out of 10, Wonderful, (1,098 reviews)
"staying there tonight again"
United States
Gerardo
The price is AU$369
includes taxes & fees
28 Nov - 29 Nov
InterContinental San Francisco by IHG
A grand lobby with a marble staircase, a chandelier, and a teal sofa.

17. The Marker Union Square San Francisco

The Marker Union Square San Francisco
4.0 star property
0.3 km from Tenderloin
9.2 out of 10, Wonderful, (1,633 reviews)
"Great place to stay!"
Canada
Samantha
The price is AU$247
includes taxes & fees
23 Nov - 24 Nov
The Marker Union Square San Francisco
A high-rise building with a distinctive arched top and multiple floors, surrounded by other buildings and city lights at night.

18. San Francisco Marriott Marquis

San Francisco Marriott Marquis
4.0 star property
South of Market, 0.9 km from Tenderloin
8.8 out of 10, Excellent, (1,295 reviews)
"Great location, great hotel and staff."
United States
Ariel
The price is AU$353
includes taxes & fees
13 Nov - 14 Nov
San Francisco Marriott Marquis
A hotel entrance with a revolving door, potted plants, and a sign for the Hyatt Regency.

19. Hyatt Regency San Francisco Downtown SOMA

Hyatt Regency San Francisco Downtown SOMA
4.0 star property
South of Market, 1 km from Tenderloin
9.4 out of 10, Exceptional, (1,344 reviews)
"Enjoyed the stay, very good location and very well maintained hotel"
United States
Julio
The price is AU$333
includes taxes & fees
22 Nov - 23 Nov
Hyatt Regency San Francisco Downtown SOMA
A spacious lobby with wooden floors, modern furniture, and large windows allowing natural light.

20. Hotel Kabuki, part of JdV by Hyatt

Hotel Kabuki, part of JdV by Hyatt
4.0 star property
1.3 km from Tenderloin
9.2 out of 10, Wonderful, (1,001 reviews)
"Very nice and calming place to stay"
United States
Filiberto
The price is AU$375
includes taxes & fees
23 Nov - 24 Nov
Hotel Kabuki, part of JdV by Hyatt
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Tenderloin Hotel Reviews

Hilton San Francisco Financial District

Hilton San Francisco Financial District

10/10 Excellent
"Amazing staff and clean room"
Yen 2-night trip
Posted 6 hours ago
Hilton San Francisco Financial District

Frequently asked questions

Are you searching for a great accommodation for your luxury trip to Tenderloin?
Use Expedia to arrange your flight to San Francisco International Airport (SFO) airport or Oakland, CA (OAK-Oakland Intl.) airport, and then choose from a variety of places to stay that will deliver the luxury you seek. Amenities are important when you plan a trip, so we make it easy to get what you'd like to make your stay relaxing and comfortable. If you want an upscale hotel with fine dining, a spa or several swimming pools, Expedia can help you find the best luxury hotel experience that Tenderloin offers. During your visit, you might want to enjoy the art and opera which Tenderloin is known for.
What's there to see and do in Tenderloin?
Take in some sights and attractions while you're in Tenderloin by visiting Golden Gate Theatre, Great American Music Hall and Van Ness Avenue. If you have spare time during your trip, you might want to make a stop at SOMA Pilipinas and UC Law San Francisc.

Explore a world of travel with Expedia