Search San Diego Santa Fe Depot hotels

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for San Diego Santa Fe Depot hotels

Keating Hotel By At Mine Hospitality

Keating Hotel By At Mine Hospitality
3.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (2 reviews)
"It was everything we needed! Clean and cozy room in a prime location and a friendly staff!"
United States
Austin Salgado
The price is AU$201
includes taxes & fees
13 May - 14 May
Keating Hotel By At Mine Hospitality

Sheraton San Diego Resort

Sheraton San Diego Resort
4.0 star property
Harbor Island
8.4 out of 10, Very good, (3,538 reviews)
"Excellent food, friendly staff, easy check-in, and beautiful setting. "
United States
Emily
The price is AU$316
includes taxes & fees
27 May - 28 May
Sheraton San Diego Resort

Best Western Yacht Harbor Hotel

Best Western Yacht Harbor Hotel
2.5 star property
Point Loma
8.4 out of 10, Very good, (1,875 reviews)
"Near some great restaurants and overall a nice hotel"
United States
John
The price is AU$157
includes taxes & fees
13 May - 14 May
Best Western Yacht Harbor Hotel

The Alcala Hotel Mission Valley/Seaworld

The Alcala Hotel Mission Valley/Seaworld
2.5 star property
Mission Valley
8.0 out of 10, Very good, (47 reviews)
"Everything was perfect, the staff very friendly place was clean and minutes away from everything ( by car )"
United States
Jorge
The price is AU$117
includes taxes & fees
19 May - 20 May
The Alcala Hotel Mission Valley/Seaworld

Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina
4.0 star property
Downtown San Diego
9.2 out of 10, Wonderful, (2,131 reviews)
"Excellent stay!"
United States
Joyce
The price is AU$409
includes taxes & fees
25 May - 26 May
Marriott Marquis San Diego Marina

Hilton Garden Inn San Diego Old Town/SeaWorld Area

Hilton Garden Inn San Diego Old Town/SeaWorld Area
3.0 star property
Old Town San Diego
8.8 out of 10, Excellent, (1,440 reviews)
"Very nice stay, would love to stay there again"
United States
Erika
The price is AU$197
includes taxes & fees
26 May - 27 May
Hilton Garden Inn San Diego Old Town/SeaWorld Area

Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld
3.0 star property
Point Loma
7.4 out of 10, Good, (4,249 reviews)
"Great overall stay. Would stay again. "
United States
German
The price is AU$141
includes taxes & fees
13 May - 14 May
Wyndham Garden San Diego Near SeaWorld

Wyndham San Diego Bayside

Wyndham San Diego Bayside
4.0 star property
Downtown San Diego
8.4 out of 10, Very good, (6,202 reviews)
"Great stay perfect location walkable to many things"
United States
Bianca
The price is AU$278
includes taxes & fees
27 May - 28 May
Wyndham San Diego Bayside

Kings Inn San Diego

Kings Inn San Diego
2.5 star property
Mission Valley
8.8 out of 10, Excellent, (3,712 reviews)
"Decent hotel for the price :)"
United States
Angel
The price is AU$159
includes taxes & fees
13 May - 14 May
Kings Inn San Diego

Bay Club Hotel & Marina

Bay Club Hotel & Marina
3.5 star property
Point Loma
9.2 out of 10, Wonderful, (3,598 reviews)
"Great location"
United States
Hui Mei
The price is AU$260
includes taxes & fees
25 May - 26 May
Bay Club Hotel & Marina

Best Western San Diego Pacific Beach/Mission Bay

Best Western San Diego Pacific Beach/Mission Bay
2.5 star property
Bay Park
8.2 out of 10, Very good, (383 reviews)
"The stay was good and close to the zoo and beach also shopping"
United States
Carol
The price is AU$138
includes taxes & fees
25 May - 26 May
Best Western San Diego Pacific Beach/Mission Bay

Hilton San Diego Airport/Harbor Island

Hilton San Diego Airport/Harbor Island
3.5 star property
Harbor Island
8.8 out of 10, Excellent, (1,209 reviews)
"Great dinner, friendly staff, clean Rooms"
United States
Heather
The price is AU$246
includes taxes & fees
25 May - 26 May
Hilton San Diego Airport/Harbor Island

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego
4.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (3,668 reviews)
"Great stay and location!"
United States
Ashtyn
The price is AU$294
includes taxes & fees
25 May - 26 May
Hard Rock Hotel San Diego

Best Western Plus Hacienda Hotel Old Town

Best Western Plus Hacienda Hotel Old Town
3.0 star property
Old Town San Diego
8.4 out of 10, Very good, (2,009 reviews)
"I highly recommend this hotel it is beautiful and the staff is great"
United States
Juanita
The price is AU$198
includes taxes & fees
25 May - 26 May
Best Western Plus Hacienda Hotel Old Town

Holiday Inn Express San Diego Airport - Old Town by IHG

Holiday Inn Express San Diego Airport - Old Town by IHG
2.5 star property
Mission Hills
9.2 out of 10, Wonderful, (1,069 reviews)
"Staff was so great nice rooms really great stay"
United States
Amelia
The price is AU$251
includes taxes & fees
25 May - 26 May
Holiday Inn Express San Diego Airport - Old Town by IHG

Bahia Resort Hotel

Bahia Resort Hotel
3.5 star property
Central Mission Beach
8.6 out of 10, Excellent, (2,072 reviews)
"Nice place to stay with the kids."
United States
Paul
The price is AU$354
includes taxes & fees
20 May - 21 May
Bahia Resort Hotel

Lafayette Hotel & Club

Lafayette Hotel & Club
4.0 star property
University Heights
9.4 out of 10, Exceptional, (1,645 reviews)
"Very accommodating and what a lovely place!!"
United States
Myra
The price is AU$395
includes taxes & fees
20 May - 21 May
Lafayette Hotel & Club

Comfort Inn Sea World Area

Comfort Inn Sea World Area
3.5 star property
Point Loma
8.6 out of 10, Excellent, (3,654 reviews)
"Will stay again"
United States
Louis
The price is AU$171
includes taxes & fees
25 May - 26 May
Comfort Inn Sea World Area

Springhill Suites San Diego Downtown/Bayfront

Springhill Suites San Diego Downtown/Bayfront
3.5 star property
Downtown San Diego
9.2 out of 10, Wonderful, (1,010 reviews)
"Great Location, nice hotel, Friendly Staff."
United States
Gary F
The price is AU$359
includes taxes & fees
27 May - 28 May
Springhill Suites San Diego Downtown/Bayfront

TownePlace Suites by Marriott San Diego Airport/Liberty Station

TownePlace Suites by Marriott San Diego Airport/Liberty Station
3.0 star property
San Diego
9.0 out of 10, Wonderful, (1,009 reviews)
"Love it great place"
United States
Derek
The price is AU$268
includes taxes & fees
25 May - 26 May
TownePlace Suites by Marriott San Diego Airport/Liberty Station
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Holiday Rentals in San Diego Santa Fe Depot

Save an average of 15% on thousands of hotels when you're signed in

Top San Diego Santa Fe Depot Hotel Reviews

Recent Reviews in San Diego Santa Fe Depot

More cheap accommodation in San Diego Santa Fe Depot

Frequently asked questions

What's the area like around San Diego Santa Fe Depot?
San Diego Santa Fe Depot is located in a scenic area of San Diego known for its array of dining options and popular zoo. If you're looking for a convenient place to stay, take a look at the 906 hotels and other accommodation options located within a mile of the station.
Where is the best place to stay close to San Diego Santa Fe Depot?
Adjacent to San Diego Santa Fe Depot, The Sofia Hotel is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and a 24-hour fitness centre. Other good options close by include Hard Rock Hotel San Diego and The DEXTRO Little Italy, BW Premier Collection.
How many hotels can I expect to find close to San Diego Santa Fe Depot?
Expedia has 906 hotels and other accommodation options within a mile from the station.
What can I see and do near San Diego Santa Fe Depot?
Study the collections at USS Midway Museum, Maritime Museum of San Diego or San Diego Air and Space Museum. Hotel del Coronado, Our Lady of the Rosary Catholic Church and Whaley House Museum are monuments to see when you're exploring the area around San Diego Santa Fe Depot. You can watch performances at San Diego Civic Theatre, The Rady Shell at Jacobs Park and Humphreys Concerts by the Bay if you're interested in local theatre.

Explore a world of travel with Expedia