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Otay Mesa Hotels, San Diego

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Our top choices for Otay Mesa hotels

1. Quality Suites San Diego Otay Mesa

Quality Suites San Diego Otay Mesa
2.5 star property
Otay Mesa
7.2 out of 10, Good, (1,009 reviews)
"Very clean, bed was comfortable!"
United States
Michael A
The price is AU$182
includes taxes & fees
16 June - 17 June
Quality Suites San Diego Otay Mesa

2. Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
2.5 star property
Otay Mesa
8.2 out of 10, Very good, (1,764 reviews)
"Clean, friendly staff, great breakfast!!"
United States
Flor
The price is AU$226
includes taxes & fees
21 June - 22 June
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

3. Crowne Plaza San Diego - Mission Valley by IHG

Crowne Plaza San Diego - Mission Valley by IHG
3.5 star property
29.8 km from Otay Mesa
8.2 out of 10, Very good, (1,050 reviews)
"Always a great stay."
United States
amanda
The price is AU$211
includes taxes & fees
29 June - 30 June
Crowne Plaza San Diego - Mission Valley by IHG

4. Sheraton San Diego Resort

Sheraton San Diego Resort
4.0 star property
28.1 km from Otay Mesa
8.4 out of 10, Very good, (3,541 reviews)
"Great location and shuttle service to and from the airport."
Canada
Malinda
The price is AU$331
includes taxes & fees
1 July - 2 July
Sheraton San Diego Resort

5. Lafayette Hotel & Club

Lafayette Hotel & Club
4.0 star property
26.8 km from Otay Mesa
9.4 out of 10, Exceptional, (1,714 reviews)
"my favorite hotel i’ve ever been to."
United States
Tianna
The price is AU$406
includes taxes & fees
15 June - 16 June
Lafayette Hotel & Club

6. Sycuan Casino Resort

Sycuan Casino Resort
4.0 star property
28.5 km from Otay Mesa
9.4 out of 10, Exceptional, (1,983 reviews)
"Always a great stay"
United States
Jeanette
The price is AU$224
includes taxes & fees
16 June - 17 June
Sycuan Casino Resort

7. Best Western Chula Vista/Otay Valley Hotel

Best Western Chula Vista/Otay Valley Hotel
2.5 star property
7.1 km from Otay Mesa
8.0 out of 10, Very good, (1,791 reviews)
"Price reflects the quality but would definitely stay here again on a budget trip. Good location for many of the things we planned to do."
United States
Lynn
The price is AU$185
includes taxes & fees
5 July - 6 July
Best Western Chula Vista/Otay Valley Hotel

8. Valli Hi Motel

Valli Hi Motel
2.5 star property
7.9 km from Otay Mesa
8.4 out of 10, Very good, (1,020 reviews)
"Great place to stay."
United States
Allan
The price is AU$140
includes taxes & fees
15 June - 16 June
Valli Hi Motel

9. Best Western San Diego Pacific Beach/Mission Bay

Best Western San Diego Pacific Beach/Mission Bay
2.5 star property
33.6 km from Otay Mesa
8.2 out of 10, Very good, (421 reviews)
"Location was great!"
United States
Richard
The price is AU$228
includes taxes & fees
28 June - 29 June
Best Western San Diego Pacific Beach/Mission Bay

10. The Alcala Hotel Mission Valley/Seaworld

The Alcala Hotel Mission Valley/Seaworld
2.5 star property
30.2 km from Otay Mesa
8.0 out of 10, Very good, (212 reviews)
"Staff was great and rooms were nice."
United States
Brittney
The price is AU$172
includes taxes & fees
15 June - 16 June
The Alcala Hotel Mission Valley/Seaworld

11. Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld
3.0 star property
31.3 km from Otay Mesa
7.4 out of 10, Good, (4,278 reviews)
"Clean room, staff was very helpful, parking was easy and accessible!"
United States
Hector
The price is AU$194
includes taxes & fees
15 June - 16 June
Wyndham Garden San Diego Near SeaWorld

12. Hampton Inn & Suites San Diego Airport Liberty Station

Hampton Inn & Suites San Diego Airport Liberty Station
2.5 star property
29.2 km from Otay Mesa
9.2 out of 10, Wonderful, (1,735 reviews)
"Good location, clean room and nice staff. A great place to stay."
United States
Patricia
The price is AU$280
includes taxes & fees
29 June - 30 June
Hampton Inn & Suites San Diego Airport Liberty Station

13. La Quinta Inn by Wyndham San Diego Chula Vista

La Quinta Inn by Wyndham San Diego Chula Vista
3.0 star property
12.9 km from Otay Mesa
8.6 out of 10, Excellent, (1,642 reviews)
"Great place to stay at, would definitely stay there again."
United States
Jose
The price is AU$179
includes taxes & fees
5 July - 6 July
La Quinta Inn by Wyndham San Diego Chula Vista

14. Days Inn by Wyndham San Diego-East/El Cajon

Days Inn by Wyndham San Diego-East/El Cajon
2.0 star property
27.3 km from Otay Mesa
7.8 out of 10, Good, (1,004 reviews)
"Rooms were cheap clean property was clean convenient close to where I was working"
United States
James
The price is AU$145
includes taxes & fees
22 June - 23 June
Days Inn by Wyndham San Diego-East/El Cajon

15. Courtyard by Marriott San Diego Airport/Liberty Station

Courtyard by Marriott San Diego Airport/Liberty Station
3.0 star property
29.7 km from Otay Mesa
9.2 out of 10, Wonderful, (1,305 reviews)
"This was an excellent experience, Loved the property, room, and outdoor walking area. Definitely recommend this hotel."
United States
Patricia
The price is AU$318
includes taxes & fees
28 June - 29 June
Courtyard by Marriott San Diego Airport/Liberty Station

16. Ocean Villa Inn

Ocean Villa Inn
2.5 star property
Ocean Beach, 33.7 km from Otay Mesa
8.0 out of 10, Very good, (1,291 reviews)
"This is very pet friendly and staff is great"
United States
Arturo
The price is AU$219
includes taxes & fees
15 June - 16 June
Ocean Villa Inn

17. Best Western Americana Inn

Best Western Americana Inn
2.5 star property
8 km from Otay Mesa
8.8 out of 10, Excellent, (1,308 reviews)
"The breakfast was great, the staff was helpful, and the room was clean and spacious!"
United States
Christopher
The price is AU$197
includes taxes & fees
28 June - 29 June
Best Western Americana Inn

18. Wyndham San Diego Bayside

Wyndham San Diego Bayside
4.0 star property
25.7 km from Otay Mesa
8.4 out of 10, Very good, (6,191 reviews)
"Great place to stay if visiting san diego recommend"
United States
Carlos
The price is AU$344
includes taxes & fees
15 June - 16 June
Wyndham San Diego Bayside

19. Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel
3.5 star property
16.9 km from Otay Mesa
9.2 out of 10, Wonderful, (3,891 reviews)
"Great stay"
United States
Cameron
The price is AU$264
includes taxes & fees
15 June - 16 June
Best Western Plus Marina Gateway Hotel

20. Holiday Inn Express San Diego Airport - Old Town by IHG

Holiday Inn Express San Diego Airport - Old Town by IHG
2.5 star property
28.8 km from Otay Mesa
9.2 out of 10, Wonderful, (1,089 reviews)
"Staff was so great nice rooms really great stay"
United States
Amelia
The price is AU$279
includes taxes & fees
17 June - 18 June
Holiday Inn Express San Diego Airport - Old Town by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Our guide on where to stay in Otay Mesa

Find the best Otay Mesa areas for the activities you enjoy most. Learn more about Otay Mesa
Learn more about Otay Mesa

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Pacific Beach

Get to Pacific Beach after the sun goes down because this is the place to be in San Diego for partying.

Mission Beach

If you're spending some time in Mission Beach, Mission Beach and Mission Bay are top sights worth seeing.

Gaslamp Quarter

The historic heart of San Diego has a fascinating history, and today is a thriving hub for food, retail and entertainment.

Mission Bay

If you're spending some time in Mission Bay, Mission Bay and Ski Beach are top sights worth seeing.

Top Otay Mesa Hotel Reviews

Frequently asked questions

What's it like in Otay Mesa?
Otay Mesa is a neighbourhood that travellers like for its beaches, restaurants and shopping.
Where is the best hotel for a stay in Otay Mesa?
Based on our traveller data, Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG is one of the top choices for your stay in Otay Mesa. This hotel offers free breakfast and an outdoor pool.
If I need to cancel my hotel reservation in Otay Mesa, will I receive a refund?
Yes! Most room reservations are refundable provided that you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Add dates, click "Search", then filter by "fully refundable" to view top deals in Otay Mesa.
What is there to do in this San Diego neighbourhood?
A few places to visit in the area around Otay Mesa include High Performance Center in Tijuana, Parque Industrial FINSA Tijuana and Otay Sports Fields. While you're out sightseeing, Caliente Casino and Alameda Otay are a couple of additional sights to visit in San Diego.

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