Illinois Medical District Hotels, Chicago

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25 Sept - 26 Sept
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26 Sept - 27 Sept
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4585 Cheap Hotels in Illinois Medical District - Specials, Reviews, & Last Minute Deals

Hyatt House Chicago Medical/University District
Exterior

Hyatt House Chicago Medical/University District

3.5 star property
9.0 out of 10, Wonderful, (1132)
"Super awesome hotel."
The price is AU$351
includes taxes & fees
2 Oct - 3 Oct
Hyatt House Chicago Medical/University District
Hyatt Place Chicago Medical/University District
Lobby

Hyatt Place Chicago Medical/University District

3.0 star property
9.0 out of 10, Wonderful, (1340)
"Great place to stay!"
The price is AU$351
includes taxes & fees
2 Oct - 3 Oct
Hyatt Place Chicago Medical/University District
Hampton Inn & Suites Chicago Medical District UIC
Business centre

Hampton Inn & Suites Chicago Medical District UIC

2.5 star property
9.6 out of 10, Exceptional, (258)
"Very clean, staff was very kind and friendly!"
The price is AU$298
includes taxes & fees
26 Oct - 27 Oct
Hampton Inn & Suites Chicago Medical District UIC
Silversmith Hotel Chicago Downtown
Lobby

Silversmith Hotel Chicago Downtown

4.0 star property
9.4 out of 10, Exceptional, (1990)
"Excellent hotel, staff, location. "
Silversmith Hotel Chicago Downtown
Bluegreen Vacations Hotel Blake, an Ascend Collection Hotel
Exterior

Bluegreen Vacations Hotel Blake, an Ascend Collection Hotel

4.0 star property
9.6 out of 10, Exceptional, (1035)
"Great stay"
The price is AU$390
includes taxes & fees
5 Oct - 6 Oct
Bluegreen Vacations Hotel Blake, an Ascend Collection Hotel
LondonHouse Chicago, Curio Collection by Hilton
Lobby

LondonHouse Chicago, Curio Collection by Hilton

4.5 star property
9.4 out of 10, Exceptional, (3325)
"Loved this hotel- best location and very nice staff. "
The price is AU$397
includes taxes & fees
19 Oct - 20 Oct
LondonHouse Chicago, Curio Collection by Hilton
citizenM Chicago Downtown
Terrace/patio

citizenM Chicago Downtown

4.0 star property
9.4 out of 10, Exceptional, (3864)
"Great stay"
The price is AU$324
includes taxes & fees
28 Sept - 29 Sept
citizenM Chicago Downtown
Hotel Riu Plaza Chicago
Front of property

Hotel Riu Plaza Chicago

4.0 star property
9.4 out of 10, Exceptional, (2480)
"Nice hotel with amazing breakfasts and location."
The price is AU$380
includes taxes & fees
1 Oct - 2 Oct
Hotel Riu Plaza Chicago
Staypineapple, An Iconic Hotel, The Loop
Interior detail

Staypineapple, An Iconic Hotel, The Loop

4.0 star property
9.4 out of 10, Exceptional, (1016)
"Great hotel!!"
The price is AU$413
includes taxes & fees
20 Oct - 21 Oct
Staypineapple, An Iconic Hotel, The Loop
The Royal Sonesta Chicago River North
Terrace/patio

The Royal Sonesta Chicago River North

4.5 star property
9.2 out of 10, Wonderful, (2152)
"Great location and great staff."
The price is AU$432
includes taxes & fees
2 Oct - 3 Oct
The Royal Sonesta Chicago River North
Thompson Chicago, by Hyatt
Restaurant

Thompson Chicago, by Hyatt

4.5 star property
9.2 out of 10, Wonderful, (1245)
"Expensive, but comfortable and in a great location "
The price is AU$416
includes taxes & fees
19 Oct - 20 Oct
Thompson Chicago, by Hyatt
Claridge House
Cocktail bar

Claridge House

4.0 star property
9.0 out of 10, Wonderful, (1386)
"We had a great stay"
The price is AU$669
includes taxes & fees
27 Sept - 28 Sept
Claridge House
Kimpton Gray Hotel by IHG
Argentinean cuisine

Kimpton Gray Hotel by IHG

4.5 star property
9.2 out of 10, Wonderful, (1012)
"Amazing stay"
The price is AU$488
includes taxes & fees
3 Oct - 4 Oct
Kimpton Gray Hotel by IHG
Virgin Hotels Chicago
Rooftop terrace

Virgin Hotels Chicago

4.5 star property
9.2 out of 10, Wonderful, (1375)
"Staff was overly friendly and the location was great!"
The price is AU$512
includes taxes & fees
28 Sept - 29 Sept
Virgin Hotels Chicago
Sable at Navy Pier Chicago, Curio Collection by Hilton
Terrace/patio

Sable at Navy Pier Chicago, Curio Collection by Hilton

4.0 star property
9.4 out of 10, Exceptional, (2166)
"I enjoyed my stay cant wait to go back. "
The price is AU$413
includes taxes & fees
2 Oct - 3 Oct
Sable at Navy Pier Chicago, Curio Collection by Hilton
Pendry Chicago
View from property

Pendry Chicago

4.5 star property
9.4 out of 10, Exceptional, (1091)
"Nice rooms and excellent service!"
The price is AU$553
includes taxes & fees
23 Oct - 24 Oct
Pendry Chicago
Sofitel Chicago Magnificent Mile
Exterior

Sofitel Chicago Magnificent Mile

4.5 star property
9.4 out of 10, Exceptional, (2144)
"Nice Stay."
The price is AU$524
includes taxes & fees
1 Oct - 2 Oct
Sofitel Chicago Magnificent Mile
L7 Chicago by LOTTE
Exterior

L7 Chicago by LOTTE

4.5 star property
9.6 out of 10, Exceptional, (3001)
"Love this hotel!"
The price is AU$493
includes taxes & fees
28 Sept - 29 Sept
L7 Chicago by LOTTE
21c Museum Hotel Chicago
Lobby

21c Museum Hotel Chicago

4.0 star property
8.8 out of 10, Excellent, (1637)
"Great place to stay!"
The price is AU$294
includes taxes & fees
5 Oct - 6 Oct
21c Museum Hotel Chicago
Ivy Boutique Hotel
Front of property

Ivy Boutique Hotel

4.5 star property
8.8 out of 10, Excellent, (1016)
"I had a wonderful stay I will definitely be back again."
The price is AU$302
includes taxes & fees
1 Oct - 2 Oct
Ivy Boutique Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Our guide on where to stay in Illinois Medical District

Find the best Illinois Medical District areas for the activities you enjoy most.
Downtown Chicago featuring a city

Downtown Chicago

The heart of the Midwest’s glittering metropolis has many offerings, from shopping and dining to parks, museums and exciting contemporary public art.

Magnificent Mile - River North

Magnificent Mile

A dazzling array of boutiques, luxury shops, famous department stores and pleasant cafés, where shopaholics can lose themselves for hours.

The Loop - Downtown which includes a river or creek

The Loop

Striking architecture, urban park space and countless entertainment options all make The Loop one of the most memorable spots in the city.

River North

Known for its fantastic nightlife, stunning river views and popular shops, there's plenty to explore in River North. Top attractions like Merchandise Mart and Bally's Casino Chicago are major draws. Catch the metro at Merchandise Mart Station or Chicago Station (Brown Line) to see more of the city.

Chicago showing a city and modern architecture

Lincoln Park

Both a neighborhood and a park, this northern Chicago area has gorgeous scenery, residential streets lined with stately homes and extensive shopping and dining.

Top Illinois Medical District Hotel Reviews

Embassy Suites by Hilton Chicago Downtown River North

Embassy Suites by Hilton Chicago Downtown River North

10/10 Excellent
"Clean room, staff was friendly & helpful. Location was perfect for us"
Kimberly 3-night trip
Posted 12 hours ago
Embassy Suites by Hilton Chicago Downtown River North

Frequently asked questions

What's it like in Illinois Medical District?

Guests are sure to enjoy their time checking out all that Chicago's Illinois Medical District neighbourhood has to offer.

Where is the best place to stay in Illinois Medical District?

Based on Expedia customer reviews, Hampton Inn & Suites Chicago Medical District UIC is the highest ranked property in Illinois Medical District. This hotel is a short 15-minute walk from United Center, and it offers free breakfast and an indoor pool. Other top choices in the neighbourhood include Hyatt House Chicago Medical/University District and Hyatt Place Chicago Medical/University District.

How many hotels are there in the Illinois Medical District area?

If you're searching for places to stay in Chicago, choose from one of Expedia's 16 hotels and other accommodation options in Illinois Medical District.

If I need to cancel my hotel reservation in Illinois Medical District, will I receive a refund?

Yes, most room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If your reservation is non-refundable, you might be able to cancel it and be given a refund within 24 hours of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to view the top deals on offer in Illinois Medical District.

What can I see and do in this Chicago neighbourhood?

Don't miss favourite places to visit in the surrounding area, such as Michigan Avenue, United Center and Soldier Field. Michael Jordan Statue and National Museum of Mexican Art are also worth a visit when you're out sightseeing in Chicago.

How can I get around Illinois Medical District and the greater Chicago area?

Ready to get out and explore the city? Polk Station (Pink Line) is the closest metro station.

Explore a world of travel with Expedia

Explore a world of travel with Expedia