Downtown South San Francisco Hotels, San Francisco

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4761 Cheap Hotels in Downtown South San Francisco - Specials, Reviews, & Last Minute Deals

La Quinta Inn & Suites by Wyndham San Francisco Airport N

3.0 star property
Downtown South San Francisco
8.0 out of 10, Very good, (2040)
"Hotel was good for the price. "
United States
Dominique
The price is AU$202
includes taxes & fees
6 Dec - 7 Dec
La Quinta Inn & Suites by Wyndham San Francisco Airport N

Airport Inn

2.0 star property
Downtown South San Francisco
8.8 out of 10, Excellent, (972)
"Very clean room, friendly staff and secure parking."
United States
Christopher
The price is AU$157
includes taxes & fees
17 Dec - 18 Dec
Airport Inn

Inn By The SFO

2.0 star property
Downtown South San Francisco
7.8 out of 10, Good, (1000)
"Excellent property!!! I would definitely recommend!!! Great stay!!! "
United States
David
Inn By The SFO

Miller Apartments

2.0 star property
Downtown South San Francisco
7.4 out of 10, Good, (15)
"Own bedroom was quiet and tidy, shared bathroom clean and tidy, good communication "
Australia
Kasey
The price is AU$225
includes taxes & fees
15 Dec - 16 Dec
Miller Apartments

Holiday Inn Express and Suites Fisherman's Wharf by IHG

3.0 star property
16.6 km from Downtown South San Francisco
9.2 out of 10, Wonderful, (2211)
"spotless, breakfast, location, all excellent I will come back!"
United States
Oscar
The price is AU$218
includes taxes & fees
7 Dec - 8 Dec
Holiday Inn Express and Suites Fisherman's Wharf by IHG

Holiday Inn Golden Gateway by IHG

3.5 star property
14.8 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (4920)
"Rooms were great, staff was great, location was great. "
United States
Jonathan
The price is AU$200
includes taxes & fees
14 Dec - 15 Dec
Holiday Inn Golden Gateway by IHG

Harbor View Inn

2.0 star property
17.7 km from Downtown South San Francisco
9.2 out of 10, Wonderful, (615)
"Nicely located "
United States
Ivan
The price is AU$224
includes taxes & fees
7 Dec - 8 Dec
Harbor View Inn

Inn at Rockaway San Francisco Pacifica

2.5 star property
8.8 km from Downtown South San Francisco
8.2 out of 10, Very good, (1001)
"Beautiful location"
United States
Elena
The price is AU$188
includes taxes & fees
4 Jan - 5 Jan 2026
Inn at Rockaway San Francisco Pacifica

Hyatt Centric Fisherman's Wharf San Francisco

4.0 star property
16.6 km from Downtown South San Francisco
8.6 out of 10, Excellent, (1465)
"Clean and great location "
United States
Shawn
The price is AU$288
includes taxes & fees
7 Dec - 8 Dec
Hyatt Centric Fisherman's Wharf San Francisco

DoubleTree by Hilton Hotel Berkeley Marina

4.0 star property
25.3 km from Downtown South San Francisco
8.2 out of 10, Very good, (3876)
"Clean Rooms great view of Marina and tasty food"
United States
Joya
The price is AU$181
includes taxes & fees
26 Dec - 27 Dec
DoubleTree by Hilton Hotel Berkeley Marina

Hotel Riu Plaza Fisherman's Wharf

4.0 star property
16.7 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (7159)
"Room was good, breakfast buffet was outstanding! "
United States
Shelly
The price is AU$241
includes taxes & fees
5 Jan - 6 Jan 2026
Hotel Riu Plaza Fisherman's Wharf

Half Moon Bay Lodge

3.0 star property
24.9 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (1071)
"Great hotel"
United States
Brian
The price is AU$221
includes taxes & fees
5 Jan - 6 Jan 2026
Half Moon Bay Lodge

FOUND Hotel Carlton, Nob Hill

2.0 star property
14.6 km from Downtown South San Francisco
8.6 out of 10, Excellent, (1089)
"Excellent location, excellence staff"
United States
james
The price is AU$108
includes taxes & fees
5 Jan - 6 Jan 2026
FOUND Hotel Carlton, Nob Hill

Hilton Garden Inn San Francisco Arpt North

3.0 star property
The East Side, 1.6 km from Downtown South San Francisco
8.4 out of 10, Very good, (1001)
"Staff, amenities, clean rooms "
United States
ROMEO JR
The price is AU$163
includes taxes & fees
20 Dec - 21 Dec
Hilton Garden Inn San Francisco Arpt North

DoubleTree by Hilton San Francisco Airport North Bayfront

4.0 star property
3.1 km from Downtown South San Francisco
8.0 out of 10, Very good, (1305)
"Great location, clean and comfortable beds "
United States
Rubia
The price is AU$174
includes taxes & fees
12 Dec - 13 Dec
DoubleTree by Hilton San Francisco Airport North Bayfront

Mayflower Hotel

2.0 star property
14.7 km from Downtown South San Francisco
8.8 out of 10, Excellent, (192)
"Great hotel, would stay again. "
United States
Bernadette
The price is AU$136
includes taxes & fees
11 Dec - 12 Dec
Mayflower Hotel

Hotel Caza Fisherman's Wharf

4.0 star property
16.7 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (3822)
"Clean property, nice staff, great location."
United States
Lori
The price is AU$255
includes taxes & fees
3 Jan - 4 Jan 2026
Hotel Caza Fisherman's Wharf

Hotel Majestic

3.5 star property
14.5 km from Downtown South San Francisco
9.2 out of 10, Wonderful, (1006)
"Friendly front desk and staff."
United States
Joanne
The price is AU$209
includes taxes & fees
14 Dec - 15 Dec
Hotel Majestic

The Lodge at Tiburon

3.5 star property
24.5 km from Downtown South San Francisco
8.8 out of 10, Excellent, (1000)
"Friendly staff, great amenities, and clean and spacious room."
United States
Jessica
The price is AU$327
includes taxes & fees
8 Dec - 9 Dec
The Lodge at Tiburon

Hilton San Francisco Financial District

4.0 star property
15.4 km from Downtown South San Francisco
8.6 out of 10, Excellent, (2085)
"Great stay "
United States
Samantha
The price is AU$159
includes taxes & fees
14 Dec - 15 Dec
Hilton San Francisco Financial District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Our guide on where to stay in Downtown South San Francisco

Find the best Downtown South San Francisco areas for the activities you enjoy most.

Union Square

Packed with a treasure trove of upmarket boutiques, designer labels and department store, shoppers will love this huge shopping plaza.

Downtown San Francisco

Known for its fascinating museums, popular shops and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and Chase Center are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.

Fisherman's Wharf

This waterfront location is steeped in history dating back to the days of the gold rush. Today, visitors come here for its vibrant atmosphere and great food.

South of Market

South of Market, or “SoMa” to the “SoCal” locals, is a huge, varied and exciting district in downtown “San Fran”.

Nob Hill

If you guessed that Nob Hill was one of San Francisco’s original “Seven Hills,” then you might just be a genius.

Top Downtown South San Francisco Hotel Reviews

Frequently asked questions

What's it like in Downtown South San Francisco?
You'll be sure to have fun exploring South San Francisco's Downtown South San Francisco neighbourhood.
What's a favourite place to stay in Downtown South San Francisco?
Based on Expedia customer reviews, La Quinta Inn & Suites by Wyndham San Francisco Airport N is a highly ranked property in Downtown South San Francisco. This hotel offers free breakfast and an outdoor pool. Other favourite options in the area include Airport Inn and Inn By The SFO.
How many hotels should I expect to find in the Downtown South San Francisco area?
When you want to put your feet up after a day of exploring the sights in South San Francisco, you can choose from 13 Expedia hotels and other accommodation options in Downtown South San Francisco.
If I need to cancel my hotel reservation in Downtown South San Francisco, will I receive a refund?
Yes, most hotel bookings are fully refundable if cancelled prior to the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to view the best options available in Downtown South San Francisco.
What can I see and do in this South San Francisco neighbourhood?
See's Candies, Cinemark Century at Tanforan and K1 Speed are just a few of the places to visit in and around Downtown South San Francisco. K1 Speed San Francisco and The Shops at Tanforan are also worth a visit when you're out sightseeing in South San Francisco.

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