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Our top choices for South San Francisco hotels

La Quinta Inn & Suites by Wyndham San Francisco Airport N

La Quinta Inn & Suites by Wyndham San Francisco Airport N
3.0 star property
Downtown South San Francisco
8.0 out of 10, Very good, (2,017 reviews)
"Awsome rooms clean overall great experience "
United States
manuel
The price is AU$177
includes taxes & fees
30 Jan - 31 Jan
La Quinta Inn & Suites by Wyndham San Francisco Airport N

DoubleTree by Hilton San Francisco South Airport Blvd

DoubleTree by Hilton San Francisco South Airport Blvd
4.0 star property
South San Francisco
8.4 out of 10, Very good, (2,091 reviews)
"Clean rooms and good location! "
United States
Khant
The price is AU$200
includes taxes & fees
30 Jan - 31 Jan
DoubleTree by Hilton San Francisco South Airport Blvd

Fairfield by Marriott Inn & Suites San Francisco Airport Oyster Point Area

Fairfield by Marriott Inn & Suites San Francisco Airport Oyster Point Area
2.5 star property
The East Side
9.0 out of 10, Wonderful, (450 reviews)
"Clean room, helpful staff, complimentary breakfast. "
United States
Veronica
The price is AU$210
includes taxes & fees
30 Jan - 31 Jan
Fairfield by Marriott Inn & Suites San Francisco Airport Oyster Point Area

Best Western Plus Grosvenor Airport Hotel

Best Western Plus Grosvenor Airport Hotel
3.0 star property
South San Francisco
8.4 out of 10, Very good, (1,731 reviews)
"Very clean and friendly staff"
United States
Heidi
The price is AU$190
includes taxes & fees
13 Feb - 14 Feb
Best Western Plus Grosvenor Airport Hotel

Sonesta Select San Francisco Airport Oyster Point Waterfront

Sonesta Select San Francisco Airport Oyster Point Waterfront
3.0 star property
Oyster Point
8.6 out of 10, Excellent, (1,944 reviews)
"Clean, good location, excellent desk services. "
United States
Marisela
The price is AU$183
includes taxes & fees
24 Jan - 25 Jan
Sonesta Select San Francisco Airport Oyster Point Waterfront

Sonesta ES Suites San Francisco Airport Oyster Point Waterfront

Sonesta ES Suites San Francisco Airport Oyster Point Waterfront
3.0 star property
Oyster Point
8.4 out of 10, Very good, (1,002 reviews)
"Great view of the bay!"
United States
Soo
The price is AU$202
includes taxes & fees
24 Jan - 25 Jan
Sonesta ES Suites San Francisco Airport Oyster Point Waterfront

Hotel Focus SFO

Hotel Focus SFO
3.0 star property
The East Side
7.6 out of 10, Good, (1,527 reviews)
"It was a great stay"
United States
Marcos
The price is AU$141
includes taxes & fees
19 Feb - 20 Feb
Hotel Focus SFO

Hilton Garden Inn San Francisco Arpt North

Hilton Garden Inn San Francisco Arpt North
3.0 star property
The East Side
8.4 out of 10, Very good, (1,009 reviews)
"Excellent and very satisfying stay. Towels, bedding, and the room were clean."
United States
Soo
The price is AU$184
includes taxes & fees
31 Jan - 1 Feb
Hilton Garden Inn San Francisco Arpt North

AC Hotel by Marriott San Francisco Airport Oyster Point/Waterfront

AC Hotel by Marriott San Francisco Airport Oyster Point/Waterfront
4.0 star property
Oyster Point
9.2 out of 10, Wonderful, (1,000 reviews)
"Great place to stay and staff are helpful. "
United States
Smile
The price is AU$253
includes taxes & fees
31 Jan - 1 Feb
AC Hotel by Marriott San Francisco Airport Oyster Point/Waterfront

Hotel Nova SFO

Hotel Nova SFO
2.5 star property
South San Francisco
8.6 out of 10, Excellent, (1,004 reviews)
"Very good, comfortable, and clean hotel. Close to the airport. "
United States
Adam
The price is AU$180
includes taxes & fees
24 Jan - 25 Jan
Hotel Nova SFO

Four Points by Sheraton Hotel & Suites San Francisco Airport

Four Points by Sheraton Hotel & Suites San Francisco Airport
3.0 star property
South San Francisco
7.8 out of 10, Good, (1,000 reviews)
"Front desk is perfect"
Mexico
Miguel
The price is AU$166
includes taxes & fees
24 Jan - 25 Jan
Four Points by Sheraton Hotel & Suites San Francisco Airport

Holiday Inn Express San Francisco-Airport North by IHG

Holiday Inn Express San Francisco-Airport North by IHG
2.5 star property
South San Francisco
8.2 out of 10, Very good, (1,003 reviews)
"Wonderful stay!"
United States
Lirio Anne
The price is AU$150
includes taxes & fees
25 Jan - 26 Jan
Holiday Inn Express San Francisco-Airport North by IHG

Home2 Suites by Hilton San Francisco Airport North

Home2 Suites by Hilton San Francisco Airport North
3.0 star property
The East Side
8.8 out of 10, Excellent, (1,182 reviews)
"Had an amazing stay here, felt like home "
United States
Miguel
The price is AU$212
includes taxes & fees
30 Jan - 31 Jan
Home2 Suites by Hilton San Francisco Airport North

Rodeway Inn South San Francisco Airport

Rodeway Inn South San Francisco Airport
2.0 star property
South San Francisco
7.0 out of 10, Good, (1,002 reviews)
"Kind employees and management, quiet and comfortable room"
United States
Michael
The price is AU$115
includes taxes & fees
22 Jan - 23 Jan
Rodeway Inn South San Francisco Airport

Embassy Suites by Hilton San Francisco Airport Oyster Point

Embassy Suites by Hilton San Francisco Airport Oyster Point
3.5 star property
The East Side
8.6 out of 10, Excellent, (1,270 reviews)
"Everything was just great the amenities the staff the cleanliness the breakfast I had a very relaxing and great time "
United States
Lily
The price is AU$256
includes taxes & fees
30 Jan - 31 Jan
Embassy Suites by Hilton San Francisco Airport Oyster Point

Hampton Inn San Francisco Airport

Hampton Inn San Francisco Airport
2.5 star property
The East Side
8.6 out of 10, Excellent, (1,005 reviews)
"Amazing place, 100% recommend "
United States
Ana catherine
The price is AU$195
includes taxes & fees
30 Jan - 31 Jan
Hampton Inn San Francisco Airport

Larkspur Landing Extended Stay Suites South San Francisco

Larkspur Landing Extended Stay Suites South San Francisco
3.0 star property
The East Side
7.8 out of 10, Good, (1,005 reviews)
"Friendly staff and the room was clean. "
United States
Sia
The price is AU$172
includes taxes & fees
1 Feb - 2 Feb
Larkspur Landing Extended Stay Suites South San Francisco

Inn By The SFO

Inn By The SFO
2.0 star property
Downtown South San Francisco
7.8 out of 10, Good, (1,001 reviews)
"Excellent property!!! I would definitely recommend!!! Great stay!!! "
United States
David
Inn By The SFO

Comfort Inn and Suites San Francisco Airport North

Comfort Inn and Suites San Francisco Airport North
2.5 star property
The East Side
7.8 out of 10, Good, (999 reviews)
"My room was very nice. Clean & quiet. The bed was great as was the gull breakfast. Thank you so much. I would stay here in the future."
United States
Julie
The price is AU$168
includes taxes & fees
23 Jan - 24 Jan
Comfort Inn and Suites San Francisco Airport North

Airport Inn

Airport Inn
2.0 star property
Downtown South San Francisco
8.8 out of 10, Excellent, (979 reviews)
"Very clean room, friendly staff and secure parking."
United States
Christopher
The price is AU$161
includes taxes & fees
22 Jan - 23 Jan
Airport Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Our guide on where to stay in South San Francisco

Find the best South San Francisco areas for the activities you enjoy most.

Downtown South San Francisco

City centre South San Francisco blends business energy with cultural richness just minutes from San Francisco proper. Modern biotech campuses stand alongside vibrant ethnic markets on Grand Avenue. The area hums with professional activity while celebrating its diverse heritage through colourful murals. This well-connected hub offers excellent transport options via BART and Caltrain stations. Authentic dining reflects the area's Hispanic and Asian communities. After business hours, the atmosphere becomes quietly residential with limited evening entertainment.

Oyster Point

Oyster Point blends sleek biotech campuses with refreshing waterfront beauty along San Francisco Bay. Modern glass buildings reflect the calm waters where walking paths invite you to explore. The area showcases contemporary plazas and public art installations throughout the business district. Corporate lunch spots serve the weekday crowd while evening options remain limited. The Bay Trail offers panoramic views and peaceful walks away from the office buzz. Visitors can observe both cutting-edge architecture and natural bay ecosystems during business hours.

The East Side

The East Side of South San Francisco blends cultural diversity with suburban charm just minutes from San Francisco Bay. Hispanic and Asian communities contribute authentic flavours to local eateries along Grand Avenue. Views of San Bruno Mountain create a distinctive backdrop for this working-class area. Visitors can explore Orange Memorial Park's recreational areas or hike nearby mountain trails. Budget-conscious travellers appreciate the area's affordable dining options and practical accommodation. Easy connections to BART and Caltrain make exploring the greater Bay Area convenient without downtown's premium prices.

Paradise Valley

Paradise Valley offers a quiet retreat from San Francisco's hustle while keeping you connected to the Bay Area. This peaceful residential area boasts wide streets and modest homes where local families live their everyday lives. Travellers appreciate the genuine suburban atmosphere and significantly lower prices than city centre. Just minutes from San Francisco International Airport, Paradise Valley serves as a practical base for exploring the region. Small local parks provide green spaces for relaxation. Though lacking tourist attractions within its boundaries, the neighborhood's proximity to major highways makes Bay Area adventures easily accessible.

Serra Highlands

Serra Highlands offers a peaceful retreat from the Bay Area bustle. This quiet area features hillside streets lined with mid-century ranch homes and contemporary houses. Morning fog creates a mystical atmosphere while eucalyptus-scented air refreshes the senses. Panoramic vistas of San Francisco Bay reward those who explore the residential streets. Small area parks and green corridors provide pleasant walking opportunities. Though dining and shopping options are limited within the area, the authentic suburban charm makes it worth the short drive to nearby commercial districts.

Stay near popular South San Francisco attractions

Learn more about South San Francisco

Perched on the edge of San Francisco Bay, this family-friendly city boasts a surprising castle and stunning mountain views. Foodies flock to local restaurants, while thrill-seekers race go-karts at K1 Speed or tour the famous See's Sweets factory.

#BVSBlue Aristodes Demetries, One Of Americas Best Known Sculptors Created This Steel Sculpture As A Symbol Of Cabot Cabot And Forbes Industrial Park. Situated 243 Feet Above Sea Level It Rises To A Be Seen From The Bay Bridge, The East Bay and SFO. Called The Wind Harp Locally. It emits eerie sounds when the wind 💨is at its strongest.
Photo by Tonette Pineda✈⛵🚌🚉🚃🚅🚀
Open Photo by Tonette Pineda✈⛵🚌🚉🚃🚅🚀

Top South San Francisco Hotel Reviews

Recent Reviews in South San Francisco

More cheap accommodation in South San Francisco

Frequently asked questions

Where is the best place for a stay in South San Francisco?
Hampton Inn San Francisco Airport is a favourite with Expedia customers. This hotel offers free breakfast and a fitness centre. Other top choices based on traveller reviews include Home2 Suites by Hilton San Francisco Airport North and AC Hotel by Marriott San Francisco Airport Oyster Point/Waterfront. See all available top hotels, or vacation rentals in South San Francisco.
What are some of the best holiday rentals that South San Francisco has to offer?
Spacious 4BR Family Retreat with Indoor Pool, Jacuzzi & Movie Room – Near SFO: This highly rated holiday home rental in South San Francisco offers an indoor pool, a balcony and a BBQ to help you feel perfectly comfortable in your new surroundings. It has 4 bedrooms, as well as a kitchen with a dishwasher, a stovetop and a microwave, so that you can cook with friends or family. You can relax into your holiday with a pool table and 1 hot tub. Another good choice for your trip to South San Francisco is Vintage San Francisco Bay Area Home. See all vacation rentals in South San Francisco.
If I need to cancel my hotel reservation in South San Francisco, will I receive a refund?
Yes, you'll find most room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in South San Francisco.
What's the best accommodation for a budget-friendly stay in South San Francisco?
Based on reviews, Hotel Focus SFO is a popular hotel for our travellers who want a more economical choice, and features free breakfast and free Wi-Fi. Other choices for your budget-friendly stay include La Quinta Inn & Suites by Wyndham San Francisco Airport N and Best Western Plus Grosvenor Airport Hotel. View all budget hotels in South San Francisco.
What's the best family accommodation in South San Francisco?
Embassy Suites by Hilton San Francisco Airport Oyster Point is a hotel with an indoor pool and a restaurant, and it's a top choice on Expedia for families. Other options to stay with the children include Comfort Inn and Suites San Francisco Airport North and Hilton Garden Inn San Francisco Arpt North. Also, attractions such as K1 Speed San Francisco and See's Candies are fun for children of all ages. Find more child-friendly accommodations in South San Francisco.
What's the best LGBTQ-friendly accommodation in South San Francisco?
DoubleTree by Hilton San Francisco South Airport Blvd is a top LGBTQ-friendly hotel that features free Wi-Fi and a fitness centre. La Quinta Inn & Suites by Wyndham San Francisco Airport N and Embassy Suites by Hilton San Francisco Airport Oyster Point are other good choices for your stay. See all available hotels listed as LGBTQ-friendly in South San Francisco.
What's the best dog-friendly hotel in South San Francisco?
DoubleTree by Hilton San Francisco South Airport Blvd is a top hotel for people travelling with their pets, and offers a fitness centre and a bar/lounge for its human guests. Two other good options for you and your pet include Embassy Suites by Hilton San Francisco Airport Oyster Point and Sonesta ES Suites San Francisco Airport Oyster Point Waterfront. See more pet-friendly hotel accommodations in South San Francisco.
What are some hotels with pools in South San Francisco?
Travelodge by Wyndham San Francisco Airport North: Features complimentary wireless Internet access, a pool and televisions. Embassy Suites by Hilton San Francisco Airport Oyster Point and Hotel Riu Plaza Fisherman's Wharf are two additional hotels that feature an on-site pool. View all hotels with pools in South San Francisco.
How is it to stay in South San Francisco?
Families will find child-friendly activities in South San Francisco, and visitors give high marks for the top-notch restaurants, shopping and local tours. This welcoming city also attracts tourists with its cafes. Around the area, top sights include San Francisco Bay, Oracle Park and Pier 39. In South San Francisco, there are 105 hotels and other accommodation options to choose from. Find out more about South San Francisco.
What should I see while I'm in South San Francisco?
Favorite family attractions include K1 Speed San Francisco and See's Candies. Natural beauty is on display at San Francisco Bay, Santa Cruz Mountains and San Bruno Point Park. Additionally, you'll find Oracle Park and Pier 39 in the area. Take a look at what more there is to see and do in Expedia's South San Francisco guide.
How can I get around South San Francisco?
Make your way to South San Francisco Metro Station for metro travel. If you want to venture outside the area, hop on a train at South San Francisco Station. If you want to venture out around the area, you may want a rental car in South San Francisco for your journey.
What's the weather like in South San Francisco?
The hottest months are usually September and August, with an average temperature of 17°C, while the coldest months are February and January, with an average of 11°C. Average annual precipitation for South San Francisco is 574 mm.

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