Cheap flights from Istanbul to Southern Madrid

View AU$138 flight on Sun, 8 Feb. 2026Opens in a new window

Popular airlines from Istanbul to Southern Madrid

  • ITA Airways

    ITA Airways

  • British Airways

    British Airways

  • Aegean

    Aegean

  • Lufthansa

    Lufthansa

  • LOT-Polish Airlines

    LOT-Polish Airlines

  • Tarom-Romanian Air Transport

    Tarom-Romanian Air Transport

  • Turkish Airlines

    Turkish Airlines

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Cheap Flights from Istanbul (IST) to Southern Madrid (MAD)

Prices were available within the past 7 days for one-way flights and round trip tickets for the period specified. Prices and availability are subject to change. Additional terms apply.

Air Serbia
Mon, 2 Mar. - Sun, 8 Mar.
IST
Istanbul
MAD
Madrid
AU$383 Return, found 3 days ago
AU$383
Return
found 3 days ago
Select Air Serbia flight, departing Mon, 2 Mar. from Istanbul to Madrid, returning Sun, 8 Mar., priced at AU$383 found 3 days ago
Aegean
Sun, 11 Jan. - Sun, 18 Jan.
IST
Istanbul
MAD
Madrid
AU$384 Return, found 19 hours ago
AU$384
Return
found 19 hours ago
Select Aegean flight, departing Sun, 11 Jan. from Istanbul to Madrid, returning Sun, 18 Jan., priced at AU$384 found 19 hours ago
SKY express
Sun, 11 Jan. - Sun, 18 Jan.
IST
Istanbul
MAD
Madrid
AU$421 Return, found 19 hours ago
AU$421
Return
found 19 hours ago
Select SKY express flight, departing Sun, 11 Jan. from Istanbul to Madrid, returning Sun, 18 Jan., priced at AU$421 found 19 hours ago
Lufthansa
Mon, 2 Mar. - Sun, 8 Mar.
IST
Istanbul
MAD
Madrid
AU$436 Return, found 3 days ago
AU$436
Return
found 3 days ago
Select Lufthansa flight, departing Mon, 2 Mar. from Istanbul to Madrid, returning Sun, 8 Mar., priced at AU$436 found 3 days ago
LOT-Polish Airlines
Wed, 17 Dec. - Wed, 24 Dec.
IST
Istanbul
MAD
Madrid
AU$457 Return, found 3 days ago
AU$457
Return
found 3 days ago
Select LOT-Polish Airlines flight, departing Wed, 17 Dec. from Istanbul to Madrid, returning Wed, 24 Dec., priced at AU$457 found 3 days ago
Air Europa
Sat, 1 Nov. - Fri, 21 Nov.
IST
Istanbul
MAD
Madrid
AU$473 Return, found 6 days ago
AU$473
Return
found 6 days ago
Select Air Europa flight, departing Sat, 1 Nov. from Istanbul to Madrid, returning Fri, 21 Nov., priced at AU$473 found 6 days ago

Find the cheapest month to fly from Istanbul (IST) to Madrid (MAD)

February is typically the cheapest month to fly

From AU$230 - AU$437 per traveller.

Graph displaying average flight prices per month

*Available to Expedia members.