Cheap flights from Des Moines to San Diego Coast

View AU$216 flight on Wed, 8 Oct. 2025Opens in a new window

Popular airlines from Des Moines to San Diego Coast

  • American Airlines

    American Airlines

  • Alaska Airlines

    Alaska Airlines

  • United

    United

  • Delta

    Delta

  • Southwest Airlines

    Southwest Airlines

  • Frontier Airlines

    Frontier Airlines

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Cheap Flights from Des Moines (DSM) to San Diego Coast (SAN)

Prices were available within the past 7 days for one-way flights and round trip tickets for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Wed, 8 Oct. - Wed, 15 Oct.
DSM
Des Moines
CLD
Carlsbad
AU$431 Return, found 16 hours ago
AU$431
Return
found 16 hours ago
Select American Airlines flight, departing Wed, 8 Oct. from Des Moines to Carlsbad, returning Wed, 15 Oct., priced at AU$431 found 16 hours ago
Delta
Wed, 8 Oct. - Wed, 15 Oct.
DSM
Des Moines
SAN
San Diego
AU$431 Return, found 16 hours ago
AU$431
Return
found 16 hours ago
Select Delta flight, departing Wed, 8 Oct. from Des Moines to San Diego, returning Wed, 15 Oct., priced at AU$431 found 16 hours ago
American Airlines
Wed, 8 Oct. - Wed, 15 Oct.
DSM
Des Moines
SAN
San Diego
AU$431 Return, found 16 hours ago
AU$431
Return
found 16 hours ago
Select American Airlines flight, departing Wed, 8 Oct. from Des Moines to San Diego, returning Wed, 15 Oct., priced at AU$431 found 16 hours ago
American Airlines
Wed, 8 Oct. - Wed, 15 Oct.
DSM
Des Moines
SAN
San Diego
AU$470 Return, found 16 hours ago
AU$470
Return
found 16 hours ago
Select American Airlines flight, departing Wed, 8 Oct. from Des Moines to San Diego, returning Wed, 15 Oct., priced at AU$470 found 16 hours ago
United
Wed, 8 Oct. - Wed, 15 Oct.
DSM
Des Moines
SAN
San Diego
AU$502 Return, found 16 hours ago
AU$502
Return
found 16 hours ago
Select United flight, departing Wed, 8 Oct. from Des Moines to San Diego, returning Wed, 15 Oct., priced at AU$502 found 16 hours ago
Alaska Airlines
Wed, 8 Oct. - Wed, 15 Oct.
DSM
Des Moines
SAN
San Diego
AU$758 Return, found 16 hours ago
AU$758
Return
found 16 hours ago
Select Alaska Airlines flight, departing Wed, 8 Oct. from Des Moines to San Diego, returning Wed, 15 Oct., priced at AU$758 found 16 hours ago

Find the cheapest month to fly from Des Moines (DSM) to San Diego (SAN)

November is typically the cheapest month to fly

From AU$208 - AU$854 per traveller.

Graph displaying average flight prices per month

*Available to Expedia members.