Cheap flights from Mexico City to Historic Route 66

View AU$267 flight on Thu, 15 Jan. 2026Opens in a new window

Popular airlines from Mexico City to Historic Route 66

  • Viva Aerobus

    Viva Aerobus

  • Volaris

    Volaris

  • Aeromexico

    Aeromexico

  • Air Canada

    Air Canada

  • Delta

    Delta

  • American Airlines

    American Airlines

  • United

    United

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Cheap Flights from Mexico City (MEX) to Historic Route 66 (CHI)

Prices were available within the past 7 days for one-way flights and round trip tickets for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Fri, 26 Sep. - Mon, 29 Sep.
MEX
Mexico City
ORD
Chicago
AU$562 Return, found 3 days ago
AU$562
Return
found 3 days ago
Select American Airlines flight, departing Fri, 26 Sep. from Mexico City to Chicago, returning Mon, 29 Sep., priced at AU$562 found 3 days ago
American Airlines
Thu, 25 Sep. - Mon, 29 Sep.
MEX
Mexico City
ORD
Chicago
AU$571 Return, found 1 hour ago
AU$571
Return
found 1 hour ago
Select American Airlines flight, departing Thu, 25 Sep. from Mexico City to Chicago, returning Mon, 29 Sep., priced at AU$571 found 1 hour ago
Aeromexico
Thu, 25 Sep. - Mon, 29 Sep.
MEX
Mexico City
ORD
Chicago
AU$582 Return, found 1 hour ago
AU$582
Return
found 1 hour ago
Select Aeromexico flight, departing Thu, 25 Sep. from Mexico City to Chicago, returning Mon, 29 Sep., priced at AU$582 found 1 hour ago
United
Fri, 26 Sep. - Mon, 29 Sep.
MEX
Mexico City
ORD
Chicago
AU$588 Return, found 3 days ago
AU$588
Return
found 3 days ago
Select United flight, departing Fri, 26 Sep. from Mexico City to Chicago, returning Mon, 29 Sep., priced at AU$588 found 3 days ago
Delta
Fri, 26 Sep. - Mon, 29 Sep.
MEX
Mexico City
ORD
Chicago
AU$606 Return, found 3 days ago
AU$606
Return
found 3 days ago
Select Delta flight, departing Fri, 26 Sep. from Mexico City to Chicago, returning Mon, 29 Sep., priced at AU$606 found 3 days ago
avianca
Fri, 26 Sep. - Mon, 29 Sep.
MEX
Mexico City
ORD
Chicago
AU$628 Return, found 3 days ago
AU$628
Return
found 3 days ago
Select avianca flight, departing Fri, 26 Sep. from Mexico City to Chicago, returning Mon, 29 Sep., priced at AU$628 found 3 days ago

Find the cheapest month to fly from Mexico City (MEX) to Chicago (ORD)

February is typically the cheapest month to fly

From AU$377 - AU$485 per traveller.

Graph displaying average flight prices per month

*Available to Expedia members.