Cheap flights from Chicago to Northeast Missouri

View AU$72 flight on Thu, 21 Aug. 2025Opens in a new window

Popular airlines from Chicago to Northeast Missouri

  • Jetstar

    Jetstar

  • Qantas Airways

    Qantas Airways

  • Virgin Australia

    Virgin Australia

  • Scoot

    Scoot

  • American Airlines

    American Airlines

  • Emirates

    Emirates

  • United

    United

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Cheap Flights from Chicago (CHI) to Northeast Missouri (STL)

Prices were available within the past 7 days for one-way flights and round trip tickets for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Fri, 12 Jun. - Mon, 15 Jun.
ORD
Chicago
STL
St. Louis
AU$499 Return, found 6 days ago
AU$499
Return
found 6 days ago
Select American Airlines flight, departing Fri, 12 Jun. from Chicago to St. Louis, returning Mon, 15 Jun., priced at AU$499 found 6 days ago
United
Fri, 12 Jun. - Mon, 15 Jun.
ORD
Chicago
STL
St. Louis
AU$522 Return, found 6 days ago
AU$522
Return
found 6 days ago
Select United flight, departing Fri, 12 Jun. from Chicago to St. Louis, returning Mon, 15 Jun., priced at AU$522 found 6 days ago
American Airlines
Fri, 12 Jun. - Mon, 15 Jun.
ORD
Chicago
STL
St. Louis
AU$531 Return, found 6 days ago
AU$531
Return
found 6 days ago
Select American Airlines flight, departing Fri, 12 Jun. from Chicago to St. Louis, returning Mon, 15 Jun., priced at AU$531 found 6 days ago
American Airlines
Fri, 12 Jun. - Mon, 15 Jun.
ORD
Chicago
STL
St. Louis
AU$546 Return, found 6 days ago
AU$546
Return
found 6 days ago
Select American Airlines flight, departing Fri, 12 Jun. from Chicago to St. Louis, returning Mon, 15 Jun., priced at AU$546 found 6 days ago
United
Fri, 12 Jun. - Mon, 15 Jun.
ORD
Chicago
STL
St. Louis
AU$552 Return, found 6 days ago
AU$552
Return
found 6 days ago
Select United flight, departing Fri, 12 Jun. from Chicago to St. Louis, returning Mon, 15 Jun., priced at AU$552 found 6 days ago
American Airlines
Fri, 12 Jun. - Mon, 15 Jun.
ORD
Chicago
STL
St. Louis
AU$561 Return, found 6 days ago
AU$561
Return
found 6 days ago
Select American Airlines flight, departing Fri, 12 Jun. from Chicago to St. Louis, returning Mon, 15 Jun., priced at AU$561 found 6 days ago

Find the cheapest month to fly from Chicago (CHI) to St. Louis (STL)

August is typically the cheapest month to fly

From AU$139 - AU$355 per traveller.

Graph displaying average flight prices per month

*Available to Expedia members.