Serra Mesa Hotels, San Diego

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Our top choices for Serra Mesa hotels

Ash&9th

Ash&9th
2.0 star property
9.4 km from Serra Mesa
8.2 out of 10, Very good, (263 reviews)
"Will stay again! "
United States
Darlene
The price is AU$119
includes taxes & fees
21 Jan - 22 Jan
Ash&9th

Comfort Inn San Diego Airport At The Harbor

Comfort Inn San Diego Airport At The Harbor
3.5 star property
11.9 km from Serra Mesa
7.8 out of 10, Good, (1,263 reviews)
"Great room, clean property and courteous staff"
United States
Reginald D.
The price is AU$154
includes taxes & fees
25 Jan - 26 Jan
Comfort Inn San Diego Airport At The Harbor

The Shoal La Jolla Beach

The Shoal La Jolla Beach
2.5 star property
13.2 km from Serra Mesa
8.8 out of 10, Excellent, (1,003 reviews)
"Super solid place to stay, clean, great staff, walk to the beach."
United Kingdom
Nick
The price is AU$196
includes taxes & fees
26 Jan - 27 Jan
The Shoal La Jolla Beach

Heritage Inn San Diego

Heritage Inn San Diego
2.0 star property
9.1 km from Serra Mesa
7.4 out of 10, Good, (1,213 reviews)
"Clean, safe, kinda walkable, but really good for the prices "
United States
Darius
The price is AU$103
includes taxes & fees
26 Jan - 27 Jan
Heritage Inn San Diego

Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego
3.0 star property
Gaslamp Quarter, 10.4 km from Serra Mesa
9.4 out of 10, Exceptional, (1,011 reviews)
"Great location and stay. "
United States
Simran
The price is AU$214
includes taxes & fees
26 Jan - 27 Jan
Staypineapple, Hotel Z, Gaslamp San Diego

La Quinta Inn & Suites by Wyndham San Diego Mission Bay

La Quinta Inn & Suites by Wyndham San Diego Mission Bay
3.0 star property
North Pacific Beach, 7.4 km from Serra Mesa
8.0 out of 10, Very good, (1,470 reviews)
"Very clean hotel and the staff very friendly and wellcoming "
United States
Sandra
The price is AU$162
includes taxes & fees
25 Jan - 26 Jan
La Quinta Inn & Suites by Wyndham San Diego Mission Bay

SureStay Hotel by Best Western San Diego Pacific Beach

SureStay Hotel by Best Western San Diego Pacific Beach
2.5 star property
Pacific Beach, 7.3 km from Serra Mesa
8.0 out of 10, Very good, (1,477 reviews)
"Clean room , good breakfast, convenient location "
United States
Angela
The price is AU$133
includes taxes & fees
26 Jan - 27 Jan
SureStay Hotel by Best Western San Diego Pacific Beach

GreenTree Inn San Diego Mission Bay

GreenTree Inn San Diego Mission Bay
2.5 star property
Pacific Beach, 7.3 km from Serra Mesa
8.0 out of 10, Very good, (1,913 reviews)
"The staff was very nice and great location"
United States
Curtis
The price is AU$126
includes taxes & fees
25 Jan - 26 Jan
GreenTree Inn San Diego Mission Bay

Pacific Shores Inn on Pacific Beach

Pacific Shores Inn on Pacific Beach
2.5 star property
North Pacific Beach, 11.1 km from Serra Mesa
8.0 out of 10, Very good, (1,002 reviews)
"Fantastic location "
Canada
Regan
The price is AU$167
includes taxes & fees
21 Jan - 22 Jan
Pacific Shores Inn on Pacific Beach

Urban Boutique Hotel

Urban Boutique Hotel
3.0 star property
Little Italy, 9.3 km from Serra Mesa
8.6 out of 10, Excellent, (1,262 reviews)
"The staff was very help full and courteous."
United States
Jesus
The price is AU$215
includes taxes & fees
21 Jan - 22 Jan
Urban Boutique Hotel

Comfort Inn Sea World Area

Comfort Inn Sea World Area
3.5 star property
8.2 km from Serra Mesa
8.6 out of 10, Excellent, (3,262 reviews)
"Great location, friendly staff 👍 "
United States
Maria
The price is AU$138
includes taxes & fees
26 Jan - 27 Jan
Comfort Inn Sea World Area

Best Western Yacht Harbor Hotel

Best Western Yacht Harbor Hotel
2.5 star property
11.8 km from Serra Mesa
8.6 out of 10, Excellent, (1,686 reviews)
"Great rate for a great stay!"
Canada
James
The price is AU$192
includes taxes & fees
26 Jan - 27 Jan
Best Western Yacht Harbor Hotel

PB Surf Beachside Inn

PB Surf Beachside Inn
2.5 star property
North Pacific Beach, 11.1 km from Serra Mesa
8.2 out of 10, Very good, (1,002 reviews)
"Really nice place to stay at"
United States
Alejandro
The price is AU$150
includes taxes & fees
27 Jan - 28 Jan
PB Surf Beachside Inn

Beach Haven - Near Pacific Beach Park

Beach Haven - Near Pacific Beach Park
2.0 star property
North Pacific Beach, 11 km from Serra Mesa
8.8 out of 10, Excellent, (1,003 reviews)
"Clean room, great staff! Highly recommend this place!"
United States
Mikensi
The price is AU$173
includes taxes & fees
21 Jan - 22 Jan
Beach Haven - Near Pacific Beach Park

Empress Hotel of La Jolla

Empress Hotel of La Jolla
3.0 star property
13.6 km from Serra Mesa
9.0 out of 10, Wonderful, (1,000 reviews)
"Great location"
United States
Rachel
The price is AU$318
includes taxes & fees
22 Jan - 23 Jan
Empress Hotel of La Jolla

Pleasant Inn

Pleasant Inn
2.5 star property
4.8 km from Serra Mesa
8.4 out of 10, Very good, (1,302 reviews)
"Great stay!"
United States
Gene
The price is AU$160
includes taxes & fees
28 Jan - 29 Jan
Pleasant Inn

Surfer Beach Hotel

Surfer Beach Hotel
3.0 star property
Pacific Beach, 10.9 km from Serra Mesa
8.2 out of 10, Very good, (1,195 reviews)
"I love surfer Beach Hotel. It’s close to Woody’s and the duck dive bar and restaurant."
United States
Richard
The price is AU$267
includes taxes & fees
25 Jan - 26 Jan
Surfer Beach Hotel

Margaritaville Hotel San Diego Gaslamp Quarter

Margaritaville Hotel San Diego Gaslamp Quarter
4.0 star property
Gaslamp Quarter, 10.5 km from Serra Mesa
9.0 out of 10, Wonderful, (1,202 reviews)
"Perfect location in the Gaslamp District. Rooms were large & clean with friendly staff. "
United States
Ginger
The price is AU$387
includes taxes & fees
22 Jan - 23 Jan
Margaritaville Hotel San Diego Gaslamp Quarter

Westgate Hotel

Westgate Hotel
4.5 star property
9.9 km from Serra Mesa
9.0 out of 10, Wonderful, (1,013 reviews)
"Great location, nice rooms and great service. Will definitely stay here again. "
United States
Ray
Westgate Hotel

Best Western Plus Bayside Inn

Best Western Plus Bayside Inn
3.0 star property
9.6 km from Serra Mesa
9.0 out of 10, Wonderful, (1,005 reviews)
"Excellent stay!"
United States
D'ette
The price is AU$259
includes taxes & fees
25 Jan - 26 Jan
Best Western Plus Bayside Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Our guide on where to stay in Serra Mesa

Find the best Serra Mesa areas for the activities you enjoy most.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Gaslamp Quarter

The historic heart of San Diego has a fascinating history, and today is a thriving hub for food, retail and entertainment.

Pacific Beach

Get to Pacific Beach after the sun goes down because this is the place to be in San Diego for partying.

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

Ocean Beach

With a secluded sunbathing beach, swimming-only beach, special surf beach, volleyball beach and dog beach, San Diego’s “OB” sure takes beaches seriously.

Top Serra Mesa Hotel Reviews

Frequently asked questions

What's it like in Serra Mesa?
Guests are sure to enjoy their time checking out all that San Diego's Serra Mesa neighbourhood has to offer. Consider a visit to Stadium Golf Center & Batting Cages as part of your Serra Mesa travel plans.
How many hotels can I expect to find in the Serra Mesa area?
Expedia has 36 hotels and other accommodation options in Serra Mesa to choose from, making this an ideal home base for exploring the greater San Diego area.
If I need to cancel my hotel reservation in Serra Mesa, will I receive a refund?
Yes, most hotel reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review top deals in Serra Mesa.
What can I see and do in this San Diego neighbourhood?
Stadium Golf Center & Batting Cages is an attraction you might want to check out while you're in Serra Mesa. When you're sightseeing in San Diego, Convoy District and Old Cactus Garden are also worth a stop.

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