Serra Mesa Hotels, San Diego

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Tonight
6 Sept - 7 Sept
Tomorrow
7 Sept - 8 Sept
Next weekend
12 Sept - 14 Sept
In two weeks
19 Sept - 21 Sept

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8898 Cheap Hotels in Serra Mesa - Specials, Reviews, & Last Minute Deals

Wyndham San Diego Bayside
Terrace/patio

Wyndham San Diego Bayside

4.0 star property
8.4 out of 10, Very good, (5882)
"An excellent place to stay"
The price is AU$307
includes taxes & fees
12 Sept - 13 Sept
Wyndham San Diego Bayside
Palihotel San Diego Gaslamp Quarter
Rooftop terrace

Palihotel San Diego Gaslamp Quarter

4.0 star property
8.8 out of 10, Excellent, (1721)
"Enjoyed the stay !! "
The price is AU$189
includes taxes & fees
29 Sept - 30 Sept
Palihotel San Diego Gaslamp Quarter
Loews Coronado Bay Resort
Exterior

Loews Coronado Bay Resort

4.0 star property
8.8 out of 10, Excellent, (1026)
"Nice rooms, great staff close to beach"
The price is AU$458
includes taxes & fees
14 Sept - 15 Sept
Loews Coronado Bay Resort
Best Western Plus Marina Gateway Hotel
Suite, 2 Queen Beds, Non Smoking, Refrigerator (with Sofabed)

Best Western Plus Marina Gateway Hotel

3.5 star property
9.2 out of 10, Wonderful, (3260)
"Good place to stay"
The price is AU$210
includes taxes & fees
14 Sept - 15 Sept
Best Western Plus Marina Gateway Hotel
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
Exterior

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

3.0 star property
9.0 out of 10, Wonderful, (1100)
"Great stay! "
The price is AU$284
includes taxes & fees
21 Sept - 22 Sept
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
The Horton Grand, Downtown/Gaslamp Quarter
Serves dinner and happy hour

The Horton Grand, Downtown/Gaslamp Quarter

3.5 star property
9.0 out of 10, Wonderful, (2514)
"Great place to stay Close all eatery"
The Horton Grand, Downtown/Gaslamp Quarter
Gaslamp Plaza Suites
Lobby

Gaslamp Plaza Suites

3.5 star property
8.8 out of 10, Excellent, (1007)
"Great stay and great for tourist "
The price is AU$205
includes taxes & fees
29 Sept - 30 Sept
Gaslamp Plaza Suites
Sentral Gaslamp Quarter
Premium bedding, pillow-top beds, desk, laptop workspace

Sentral Gaslamp Quarter

3.0 star property
9.2 out of 10, Wonderful, (348)
"Great place to stay!"
The price is AU$339
includes taxes & fees
28 Sept - 29 Sept
Sentral Gaslamp Quarter
The Sofia Hotel
Front of property

The Sofia Hotel

3.5 star property
8.4 out of 10, Very good, (1553)
"Great Hotel. Very close to Little Italy, The Whaley House, The San Diego Zoo, and many more locations."
The Sofia Hotel
El Cordova Hotel on Coronado Island
Lobby

El Cordova Hotel on Coronado Island

3.5 star property
8.8 out of 10, Excellent, (1003)
"Perfect location! Close to beach, harbor and lots of dining options. Staff is very friendly and helpful. We stayed in the large suite which exceeded our expectations in every way."
The price is AU$356
includes taxes & fees
21 Sept - 22 Sept
El Cordova Hotel on Coronado Island
The Bristol Hotel San Diego
Property entrance

The Bristol Hotel San Diego

3.5 star property
8.4 out of 10, Very good, (1371)
"Great stay"
The Bristol Hotel San Diego
Alma San Diego Downtown, a Tribute Portfolio Hotel
Room, 1 King Bed, Balcony, City View

Alma San Diego Downtown, a Tribute Portfolio Hotel

4.0 star property
9.0 out of 10, Wonderful, (787)
"Great place to stay in Downtown SD. Convenient location, nice hotel for a good price, friendly and accommodating staff. Would stay here again!"
The price is AU$336
includes taxes & fees
21 Sept - 22 Sept
Alma San Diego Downtown, a Tribute Portfolio Hotel
Legacy Resort Hotel & Spa
Garden

Legacy Resort Hotel & Spa

4.0 star property
9.2 out of 10, Wonderful, (2846)
"Amazing place to stay. "
The price is AU$256
includes taxes & fees
22 Sept - 23 Sept
Legacy Resort Hotel & Spa
La Pensione Hotel
Exterior

La Pensione Hotel

3.0 star property
8.6 out of 10, Excellent, (1835)
"Great location and wonderful staff. "
La Pensione Hotel
The Dana on Mission Bay
2 outdoor pools, a heated pool, pool loungers

The Dana on Mission Bay

3.5 star property
8.8 out of 10, Excellent, (3706)
"We loved the place 💯"
The price is AU$353
includes taxes & fees
7 Sept - 8 Sept
The Dana on Mission Bay
Glorietta Bay Inn Coronado Island
Front of property - evening/night

Glorietta Bay Inn Coronado Island

3.5 star property
8.6 out of 10, Excellent, (1000)
"Excellent staff and location."
The price is AU$438
includes taxes & fees
10 Sept - 11 Sept
Glorietta Bay Inn Coronado Island
Staypineapple, Hotel Z, Gaslamp San Diego
Premium bedding, pillow-top beds, desk, blackout curtains

Staypineapple, Hotel Z, Gaslamp San Diego

3.0 star property
9.4 out of 10, Exceptional, (1002)
"Great location | center of action | nearby restaurants and bars | great service from staff | excellent room | great amenities"
The price is AU$301
includes taxes & fees
21 Sept - 22 Sept
Staypineapple, Hotel Z, Gaslamp San Diego
Days Inn by Wyndham San Diego Hotel Circle
Outdoor pool, a heated pool

Days Inn by Wyndham San Diego Hotel Circle

3.0 star property
7.8 out of 10, Good, (2308)
"We enjoyed our stay "
The price is AU$156
includes taxes & fees
8 Sept - 9 Sept
Days Inn by Wyndham San Diego Hotel Circle
Bay Club Hotel & Marina
Exterior

Bay Club Hotel & Marina

3.5 star property
9.0 out of 10, Wonderful, (2871)
"Love to stay here when we come to San Diego "
The price is AU$271
includes taxes & fees
8 Sept - 9 Sept
Bay Club Hotel & Marina
Urban Boutique Hotel
Check-in/check-out kiosk

Urban Boutique Hotel

3.0 star property
8.6 out of 10, Excellent, (1240)
"Great hotel and excellent location!"
Urban Boutique Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Our guide on where to stay in Serra Mesa

Find the best Serra Mesa areas for the activities you enjoy most.

Downtown San Diego

2 out of top 10 points of interest in this area

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Gaslamp Quarter featuring a bar, street scenes and a city

Gaslamp Quarter

The historic heart of San Diego has a fascinating history, and today is a thriving hub for food, retail and entertainment.

Pacific Beach Park featuring a beach

Pacific Beach

Get to Pacific Beach after the sun goes down because this is the place to be in San Diego for partying.

Belmont Park which includes a garden and rides

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

Ocean Beach

With a secluded sunbathing beach, swimming-only beach, special surf beach, volleyball beach and dog beach, San Diego’s “OB” sure takes beaches seriously.

Top Serra Mesa Hotel Reviews

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What's it like in Serra Mesa?

Guests are sure to enjoy their time checking out all that San Diego's Serra Mesa neighbourhood has to offer. Consider a visit to Stadium Golf Center & Batting Cages as part of your Serra Mesa travel plans.

How many hotels can I expect to find in the Serra Mesa area?

Expedia has 35 hotels and other accommodation options in Serra Mesa to choose from, making this an ideal home base for exploring the greater San Diego area.

If I need to cancel my hotel reservation in Serra Mesa, will I receive a refund?

Yes, most hotel reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review top deals in Serra Mesa.

What can I see and do in this San Diego neighbourhood?

Stadium Golf Center & Batting Cages is an attraction you might want to check out while you're in Serra Mesa. When you're sightseeing in San Diego, Convoy District and Old Cactus Garden are also worth a stop.