Serra Mesa Hotels, San Diego
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Our top choices for Serra Mesa hotels
Best Western Americana Inn
Best Western Americana Inn28.1 km from Serra Mesa
9.0 out of 10, Wonderful, (1,284 reviews)
"Everything was very pleasant,the place was super clean, and the breakfast was delicious👍"
Nancy
The price is AU$185
includes taxes & fees
28 May - 29 May
Sycuan Casino Resort
Sycuan Casino Resort28.8 km from Serra Mesa
9.4 out of 10, Exceptional, (1,925 reviews)
"It is a perfect hotel if breakfast is included in the stay."
Tugba
The price is AU$168
includes taxes & fees
26 May - 27 May
The Alcala Hotel Mission Valley/Seaworld
The Alcala Hotel Mission Valley/Seaworld6.6 km from Serra Mesa
8.0 out of 10, Very good, (64 reviews)
"Everything was perfect, the staff very friendly place was clean and minutes away from everything ( by car )"
Jorge
The price is AU$133
includes taxes & fees
26 May - 27 May
Lafayette Hotel & Club
Lafayette Hotel & Club5.3 km from Serra Mesa
9.4 out of 10, Exceptional, (1,652 reviews)
"This is a must stay place in San Diego"
Kristi
The price is AU$391
includes taxes & fees
19 May - 20 May
Sheraton San Diego Resort
Sheraton San Diego Resort10.1 km from Serra Mesa
8.4 out of 10, Very good, (3,533 reviews)
"Excellent food, friendly staff, easy check-in, and beautiful setting. "
Emily
The price is AU$342
includes taxes & fees
24 May - 25 May
Ramada by Wyndham San Diego Poway Miramar
Ramada by Wyndham San Diego Poway Miramar18.2 km from Serra Mesa
7.2 out of 10, Good, (1,005 reviews)
"Well maintained property, staff were professional and very nice"
Cherie
The price is AU$130
includes taxes & fees
25 May - 26 May
Best Western Plus Marina Gateway Hotel
Best Western Plus Marina Gateway Hotel16.1 km from Serra Mesa
9.2 out of 10, Wonderful, (3,824 reviews)
"Great resort "
Ines
The price is AU$230
includes taxes & fees
20 May - 21 May
Holiday Inn Express San Diego South - Chula Vista by IHG
Holiday Inn Express San Diego South - Chula Vista by IHG18.5 km from Serra Mesa
9.4 out of 10, Exceptional, (1,155 reviews)
"Very nice place to stay"
Lingzhi
The price is AU$208
includes taxes & fees
25 May - 26 May
Hilton Garden Inn San Diego Old Town/SeaWorld Area
Hilton Garden Inn San Diego Old Town/SeaWorld AreaOld Town San Diego, 7.4 km from Serra Mesa
8.8 out of 10, Excellent, (1,446 reviews)
"Very nice stay, would love to stay there again"
Erika
The price is AU$186
includes taxes & fees
26 May - 27 May
Comfort Inn Chula Vista San Diego South
Comfort Inn Chula Vista San Diego South18.6 km from Serra Mesa
8.2 out of 10, Very good, (1,498 reviews)
"We really enjoyed our stay here! Breakfast in the morning was great & staff was always friendly & helpful!"
Megan
The price is AU$165
includes taxes & fees
25 May - 26 May
Best Western San Diego/Miramar Hotel
Best Western San Diego/Miramar Hotel10.1 km from Serra Mesa
8.0 out of 10, Very good, (1,333 reviews)
"Wonderful, kind staff and good breakfast"
Kimberly
The price is AU$166
includes taxes & fees
19 May - 20 May
GreenTree Inn San Diego Mission Bay
GreenTree Inn San Diego Mission BayPacific Beach, 7.3 km from Serra Mesa
8.0 out of 10, Very good, (2,107 reviews)
"Great experience, will stay here again"
Victoria
The price is AU$147
includes taxes & fees
25 May - 26 May
Wyndham Garden San Diego Near SeaWorld
Wyndham Garden San Diego Near SeaWorld9 km from Serra Mesa
7.4 out of 10, Good, (4,231 reviews)
"Great overall stay. Would stay again. "
German
The price is AU$143
includes taxes & fees
31 May - 1 June
San Diego Mission Bay Resort
San Diego Mission Bay ResortMission Bay, 7.2 km from Serra Mesa
8.6 out of 10, Excellent, (1,443 reviews)
"Perfect place for a family trip "
Krystal
The price is AU$410
includes taxes & fees
20 May - 21 May
Marriott Marquis San Diego Marina
Marriott Marquis San Diego Marina10.8 km from Serra Mesa
9.2 out of 10, Wonderful, (2,131 reviews)
"Excellent stay!"
Joyce
The price is AU$415
includes taxes & fees
25 May - 26 May
Wyndham San Diego Bayside
Wyndham San Diego Bayside9.9 km from Serra Mesa
8.4 out of 10, Very good, (6,168 reviews)
"Was a pleasant property where the restaurant attached has great dining options"
Rika
The price is AU$323
includes taxes & fees
25 May - 26 May
The Encinitan Hotel & Suites
The Encinitan Hotel & Suites30.8 km from Serra Mesa
8.2 out of 10, Very good, (1,548 reviews)
"Really great location and kind staff!! "
Sarah
The price is AU$204
includes taxes & fees
26 May - 27 May
Holiday Inn Express San Diego Airport - Old Town by IHG
Holiday Inn Express San Diego Airport - Old Town by IHG7.9 km from Serra Mesa
9.2 out of 10, Wonderful, (1,059 reviews)
"Staff was so great nice rooms really great stay"
Amelia
The price is AU$254
includes taxes & fees
25 May - 26 May
Old Town Inn
Old Town Inn8.1 km from Serra Mesa
9.2 out of 10, Wonderful, (1,872 reviews)
"Nice staff, so clean, very pleasant stay."
Rachel
The price is AU$246
includes taxes & fees
19 May - 20 May
Pleasant Inn
Pleasant Inn4.8 km from Serra Mesa
8.6 out of 10, Excellent, (1,407 reviews)
"Staff was very friendly and helpful. Good location for sights we wanted to see."
Steve
The price is AU$123
includes taxes & fees
7 June - 8 June
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Our guide on where to stay in Serra Mesa
Find the best Serra Mesa areas for the activities you enjoy most.
Downtown San Diego
Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.
Pacific Beach
Get to Pacific Beach after the sun goes down because this is the place to be in San Diego for partying.
Mission Beach
If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.
Gaslamp Quarter
The historic heart of San Diego has a fascinating history, and today is a thriving hub for food, retail and entertainment.
Mission Bay
If you're spending some time in Mission Bay, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.
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