Serra Mesa Holidays from AU$746

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Your Serra Mesa Holiday

Take the stress and hassle out of organising your next escape with a Serra Mesa holiday package. Immerse yourself in the sights and sounds of this captivating neighbourhood and experience everything it has to offer. Your trip to Serra Mesa wouldn't be complete without a visit to big-name attractions nearby such as Snapdragon Stadium, Fashion Valley Mall and Mission Valley Mall. No matter what your dream Serra Mesa holiday may look like, you can make it a reality with Expedia.

Top Holiday Package Deals in Serra Mesa

Price found within the past 48 hours. Click for updated prices.
Handlery Hotel

Handlery Hotel

Mission Valley
AU$746
per person
19 Nov - 21 Nov
found 5 hours ago
Return direct flight included
New York (NYC) to San Diego (SAN)
8.4/10 Very good! (2,973 reviews)
The Sofia Hotel

The Sofia Hotel

Downtown San Diego
AU$851
per person
19 Nov - 21 Nov
found 5 hours ago
Return direct flight included
New York (NYC) to San Diego (SAN)
8.6/10 Excellent! (2,695 reviews)
The property was clean, the self-parking was easy to get in and out of, the bed was very firm, we woke up with some back pain, and the staff at the front desk were not very friendly. Felt like we were bothering them if we had any questions. I would like to visit San Diego again, but I probably won’t stay here again.

Reviewed on 19 Oct 2026

The Wayfarer San Diego

The Wayfarer San Diego

Mission Beach
AU$891
per person
19 Nov - 21 Nov
found 5 hours ago
Return direct flight included
New York (NYC) to San Diego (SAN)
9.4/10 Exceptional! (1,925 reviews)
We had a wonderful experience at the Wayfair Hotel. Our room was right near the pool so very easy access. The pool area felt cozy, private, but right next to the action and Boardwalk when you wanted to get out. Staff and location was excellent. We would definitely stay again.

Reviewed on 19 Oct 2026

Hotel Z

Hotel Z

Downtown San Diego
AU$763
per person
19 Nov - 21 Nov
found 5 hours ago
Return direct flight included
New York (NYC) to San Diego (SAN)
9.2/10 Wonderful! (1,191 reviews)
Urban Boutique Hotel

Urban Boutique Hotel

Downtown San Diego
AU$774
per person
19 Nov - 21 Nov
found 5 hours ago
Return direct flight included
New York (NYC) to San Diego (SAN)
8.6/10 Excellent! (1,247 reviews)
Great staff, room was clean, the AC worked perfectly. Quiet. No issues at all

Reviewed on 19 Oct 2026

Our guide on where to stay in Serra Mesa

Find the best Serra Mesa areas and neighborhoods for the activities you enjoy most. Learn more about Serra Mesa
A grand building with a central fountain, palm trees, and a flag.

Downtown San Diego

3 out of top 10 points of interest in this area

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

A pier extending into calm waters with people on it and a sandy beach with seaweed and a few individuals.

Pacific Beach

Get to Pacific Beach after the sun goes down because this is the place to be in San Diego for partying.

A lively street scene with outdoor seating at various bars and restaurants, including 'The Field' and 'Sloppy Joe's'.

Gaslamp Quarter

The historic heart of San Diego has a fascinating history, and today is a thriving hub for food, retail and entertainment.

A sandy beach with a lifeguard tower, ocean waves, and people in the distance.

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

An aerial view of a coastal city with a marina, a large body of water, and a peninsula with buildings.

Mission Bay

1 out of top 10 points of interest in this area

If you're spending some time in Mission Bay, Mission Bay and Ski Beach are top sights worth seeing.

Our pick of the best Serra Mesa Hotel Deals

Wyndham San Diego Bayside

Wyndham San Diego Bayside

1355 N Harbor Drive San Diego CA
Fully refundableReserve now, pay when you stay
AU$279
1 Nov - 2 Nov
includes taxes & fees
Wyndham San Diego Bayside
Handlery Hotel

Handlery Hotel

950 Hotel Cir N San Diego CA
Fully refundableReserve now, pay when you stay
AU$166
15 Nov - 16 Nov
includes taxes & fees
Handlery Hotel
Bay Club Hotel & Marina

Bay Club Hotel & Marina

2131 Shelter Island Dr San Diego CA
Fully refundableReserve now, pay when you stay
AU$233
28 Oct - 29 Oct
includes taxes & fees
9.2/10 Wonderful! (4,032 reviews)
"Our room was great with a nice private balcony looking out into the bay. The pool was great and the food and drinks spot on. We will be back!"

Reviewed on 19 Oct 2026

Bay Club Hotel & Marina
See all 9,187 properties in Serra Mesa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Serra Mesa holiday package cost?
Be ready to book, because a trip to Serra Mesa starts from just AU$746. When you bundle your hotels, flights and car rentals into a package, you'll land the lowest prices.
How do I get a cheap travel package to Serra Mesa?
One of the simplest ways to save dollars (and time) is to bundle your bookings with Expedia. Flights, hotels, activities and rental cars — we've got everything you need. Pick the combination that best suits you and watch your savings pile up. Of course, a travel package is never one-size-fits-all. That's why we offer more than 550 partner airlines and 1 000 000 hotel options worldwide, which lets you customize your Serra Mesa holiday.
Where should I stay in Serra Mesa?
Most visitors to Serra Mesa put both San Diego Zoo and Balboa Park on their itineraries. Why not go for a hotel that's close to these fantastic attractions?
What are the top hotels in Serra Mesa?
Get your escape off to an excellent start by locking in a room at Central Location - 3br/2ba. Stay Weekly. Clean. It's one of most sought-after properties in Serra Mesa. Another comfortable option is Newly Remodeled Beautiful Beach Bound And Centrally Located San Diego Home.
How far in advance should I book my Serra Mesa holiday?
It's difficult to pick the best time for airfares, but we normally say the earlier, the better. Most international flights on Expedia become available up to 12 months in advance. If you're booking late, fear not. Budget prices appear from time to time just weeks before departure dates.
What does an Expedia Serra Mesa travel package include?
From flights and hotels to rental cars, Expedia can help you craft a Serra Mesa package that's perfect for you. Holidaying for a few weeks? Consider a flight, hotel and rental car bundle. If your break is short, a flight and hotel deal could be what you're after. Experiences can also be added once you've made your booking. Our travel packages make it a cinch to plan and save.
What should I know before booking a Serra Mesa travel package?
You can save a tidy sum by combining your hotels, airfares and rental cars. Once you've made your booking, you can add on things like day tours or experiences. Your next unforgettable holiday is only a few clicks away.
Can I choose my airline with a Serra Mesa Expedia holiday package?
With a holiday package, you're the one in charge. Whether you'd like to fly to Serra Mesa in economy or first class, simply choose from the available airline options. Expedia has access to over 550 partner airlines all over the world.
If I'm not able to travel, can I cancel my Serra Mesa holiday package?
Plans can change in the blink of an eye, so yes. You may be able to cancel or alter your Serra Mesa holiday package at no cost if you've booked in the last 24 hours. For bookings made more than 24 hours ago, you can still make the necessary changes, but your car rental company, hotel or airline may impose a charge. Want more information? Check out our Customer Service Portal. We'll help make sure your getaway goes off without a hitch.

Stay near popular Serra Mesa attractions

Stadium Golf Center & Batting Cages

Enjoy a round of golf in San Diego at Stadium Golf Center & Batting Cages. Attend a sporting event or discover the beautiful sunsets in this walkable area.
See properties

Activities

San Diego Old Town Trolley Hop-On Hop-Off Tour

San Diego Old Town Trolley Hop-On Hop-Off Tour

AU$80
per adult
94% of travellers recommend
San Diego Old Town Trolley Hop-On Hop-Off Tour
San Diego Whale Watching Tour

San Diego Whale Watching & Dolphin Cruise

AU$100
per adult
88% of travellers recommend
San Diego Whale Watching & Dolphin Cruise
See all activities in San Diego
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.