San Juan de Dios Hotels, Guadalajara

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Check prices for these dates

Tonight
12 Nov - 13 Nov
Tomorrow
13 Nov - 14 Nov
This weekend
13 Nov - 15 Nov
Next weekend
20 Nov - 22 Nov

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Our top choices for San Juan de Dios hotels

A courtyard with a stone fountain, large leafy plants, a tiled floor, and a staircase with chairs.

1. Hotel Gallo Rubio

Hotel Gallo Rubio
2.5 star property
San Juan de Dios
8.0 out of 10, Very good, (451 reviews)
"Everything was really good thank you"
United States
Ismael
The price is AU$39
includes taxes & fees
13 Nov - 14 Nov
Hotel Gallo Rubio
A hotel room with four beds, each with white and red bedding, a ceiling fan, a TV, and artwork on the walls.

2. Gran Hotel Galerias Plaza

Gran Hotel Galerias Plaza
2.5 star property
San Juan de Dios
3.6 out of 10, (182 reviews)
"."
Mexico
María José
The price is AU$14
includes taxes & fees
8 Dec - 9 Dec
Gran Hotel Galerias Plaza
A restaurant with large windows, black wicker chairs, and a view of the cityscape.

3. Hotel Aló Degollado

Hotel Aló Degollado
4.0 star property
Downtown Guadalajara, 0.6 km from San Juan de Dios
9.6 out of 10, Exceptional, (382 reviews)
"I loved this hotel. The location was central to so many landmark locations."
United States
Brianna
The price is AU$74
includes taxes & fees
15 Nov - 16 Nov
Hotel Aló Degollado
A modern kitchen with a central island, bar stools, and a hanging light fixture.

4. Motto by Hilton Guadalajara Centro Historico

Motto by Hilton Guadalajara Centro Historico
Downtown Guadalajara, 0.8 km from San Juan de Dios
9.6 out of 10, Exceptional, (50 reviews)
"The hotel is beautiful, excellent staff, and walking distance to many attractions."
United States
Rachel
The price is AU$113
includes taxes & fees
13 Dec - 14 Dec
Motto by Hilton Guadalajara Centro Historico
A modern interior with a wooden floor, a wall-mounted shelf with decorative items, and a large mirror reflecting the room.

5. Hotel Plaza Genova Centro

Hotel Plaza Genova Centro
3.5 star property
Downtown Guadalajara, 0.9 km from San Juan de Dios
9.0 out of 10, Wonderful, (2,511 reviews)
"Excellent location, friendly and helpful staff"
United States
Martha
The price is AU$78
includes taxes & fees
17 Nov - 18 Nov
Hotel Plaza Genova Centro
A hotel entrance with a stone facade, arched windows, and a central doorway.

6. Hotel De Mendoza

Hotel De Mendoza
3.5 star property
Downtown Guadalajara, 0.9 km from San Juan de Dios
9.2 out of 10, Wonderful, (1,572 reviews)
"Well maintained for a historic center hotel."
United States
Alexander
The price is AU$108
includes taxes & fees
17 Nov - 18 Nov
Hotel De Mendoza
A spacious lobby with a high ceiling, a chandelier, a reception desk, and a seating area with armchairs and a sofa.

7. Hotel Real Maestranza

Hotel Real Maestranza
3.5 star property
Downtown Guadalajara, 1.1 km from San Juan de Dios
9.6 out of 10, Exceptional, (2,321 reviews)
"We were only at this hotel one day but I was very impressed on how beautiful, clean & attentive the staff was! 👍👍 The 24 hr restaurant was convenient & the food was very delicious. I look forward to staying there again in the future!!"
United States
Sandra
The price is AU$92
includes taxes & fees
18 Nov - 19 Nov
Hotel Real Maestranza
A hallway with columns, a wooden door, and a chandelier.

8. San Francisco Plaza Hotel

San Francisco Plaza Hotel
3.0 star property
Downtown Guadalajara, 1.1 km from San Juan de Dios
8.4 out of 10, Very good, (999 reviews)
"The rooms are very nice"
United States
David
The price is AU$74
includes taxes & fees
13 Nov - 14 Nov
San Francisco Plaza Hotel
A modern restaurant with wooden flooring, glass partitions, and a view of the cityscape.

9. DoubleTree by Hilton Guadalajara Centro Historico

DoubleTree by Hilton Guadalajara Centro Historico
3.5 star property
Downtown Guadalajara, 1.3 km from San Juan de Dios
8.8 out of 10, Excellent, (1,749 reviews)
"The overall stay was very nice! I really enjoyed staying there!"
United States
Ernesto
The price is AU$157
includes taxes & fees
29 Nov - 30 Nov
DoubleTree by Hilton Guadalajara Centro Historico
A modern lobby with a polished marble floor, a seating area with sofas, and a large glass window offering a view of the street.

10. Hotel Universo Guadalajara

Hotel Universo Guadalajara
3.0 star property
Downtown Guadalajara, 1 km from San Juan de Dios
8.2 out of 10, Very good, (1,003 reviews)
"Excelente hotel"
Mexico
Dulce Beatriz
The price is AU$68
includes taxes & fees
15 Nov - 16 Nov
Hotel Universo Guadalajara
A hotel room with a large bed, a view of a cathedral through a window, and a balcony with a railing.

11. Hotel Fenix

Hotel Fenix
3.0 star property
Downtown Guadalajara, 1.1 km from San Juan de Dios
7.8 out of 10, Good, (1,000 reviews)
"It was a great budget experience"
United States
Manuel
The price is AU$84
includes taxes & fees
13 Dec - 14 Dec
Hotel Fenix
A cozy outdoor seating area with wicker furniture and a glass coffee table, surrounded by lush greenery and a moss-covered wall.

12. Hotel Aranzazú Eco

Hotel Aranzazú Eco
3.0 star property
Downtown Guadalajara, 1.2 km from San Juan de Dios
7.8 out of 10, Good, (1,002 reviews)
"It’s a good place to stay near the center of the city."
United States
Janeth
The price is AU$82
includes taxes & fees
13 Dec - 14 Dec
Hotel Aranzazú Eco
A lobby with a fountain, red and grey seating, and a chandelier.

13. Hotel Frances

Hotel Frances
3.0 star property
Downtown Guadalajara, 1 km from San Juan de Dios
8.0 out of 10, Very good, (1,000 reviews)
"Excellent staff, the hotel is in a great location."
United States
Sarai
The price is AU$79
includes taxes & fees
24 Nov - 25 Nov
Hotel Frances
A rooftop pool with a view of a historic tower, lounge chairs, and potted plants.

14. Hotel Santiago de Compostela

Hotel Santiago de Compostela
3.5 star property
Downtown Guadalajara, 1.3 km from San Juan de Dios
9.2 out of 10, Wonderful, (1,709 reviews)
"Lovely place"
United States
Marilyn
The price is AU$71
includes taxes & fees
16 Nov - 17 Nov
Hotel Santiago de Compostela
A multi-level atrium with balconies, potted plants, and seating areas.

15. Hotel Don Quijote Plaza

Hotel Don Quijote Plaza
3.0 star property
Downtown Guadalajara, 1.1 km from San Juan de Dios
8.6 out of 10, Excellent, (1,000 reviews)
"Very clean and quiet"
United States
Aracely
The price is AU$46
includes taxes & fees
6 Dec - 7 Dec
Hotel Don Quijote Plaza
A spacious interior with high ceilings, arched columns, and a balcony overlooking the courtyard.

16. Hotel Morales Historical & Colonial Downtown Core

Hotel Morales Historical & Colonial Downtown Core
3.5 star property
Downtown Guadalajara, 1.1 km from San Juan de Dios
9.6 out of 10, Exceptional, (2,264 reviews)
"Great place"
United States
Manuel
The price is AU$93
includes taxes & fees
13 Dec - 14 Dec
Hotel Morales Historical & Colonial Downtown Core
A modern lobby with a staircase, a reception desk, and a yellow sofa.

17. Perla Central Hotel

Perla Central Hotel
3.5 star property
Downtown Guadalajara, 1.3 km from San Juan de Dios
8.6 out of 10, Excellent, (1,002 reviews)
"Good location to be around the historic center."
United States
Jesus
The price is AU$69
includes taxes & fees
16 Nov - 17 Nov
Perla Central Hotel
An indoor dining area with green chairs and tables, a bar with a TV, and a decorative wall with a geometric pattern.

18. Origen 438 Luxury Boutique Hotel

Origen 438 Luxury Boutique Hotel
4.0 star property
Downtown Guadalajara, 1.4 km from San Juan de Dios
9.8 out of 10, Exceptional, (628 reviews)
"Amazing experience. Would definitely stay here again!"
United States
Karina
The price is AU$121
includes taxes & fees
7 Dec - 8 Dec
Origen 438 Luxury Boutique Hotel
A modern lobby with a sofa, chairs, a coffee table, a large TV, and a potted plant.

19. Hotel Alcalà Centro

Hotel Alcalà Centro
3.0 star property
Downtown Guadalajara, 1.2 km from San Juan de Dios
8.2 out of 10, Very good, (216 reviews)
"Great location for wandering the historic centre. Very large modern room with a view of the beautiful church. The room had everything we needed. Bed was very comfortable, good hot shower and nice toiletries. We would happily stay again."
Canada
Elmus Todd
The price is AU$60
includes taxes & fees
24 Nov - 25 Nov
Hotel Alcalà Centro
A hotel room with two beds, a desk, a chair, a TV, and a balcony with a city view.

20. One Guadalajara Centro Histórico

One Guadalajara Centro Histórico
3.0 star property
Downtown Guadalajara, 1.2 km from San Juan de Dios
8.0 out of 10, Very good, (1,168 reviews)
"Breakfast was great, perfect area and staff was helpful"
United States
Luis
The price is AU$131
includes taxes & fees
8 Dec - 9 Dec
One Guadalajara Centro Histórico
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare top hotels in San Juan de Dios

A courtyard with a stone fountain, large leafy plants, a tiled floor, and a staircase with chairs.

Hotel Gallo Rubio

2.5 star property
San Juan de Dios
View
A hotel room with four beds, each with white and red bedding, a ceiling fan, a TV, and artwork on the walls.

Gran Hotel Galerias Plaza

2.5 star property
San Juan de Dios
View
A restaurant with large windows, black wicker chairs, and a view of the cityscape.

Hotel Aló Degollado

4.0 star property
Downtown Guadalajara, 0.6 km from San Juan de Dios
View
A modern kitchen with a central island, bar stools, and a hanging light fixture.

Motto by Hilton Guadalajara Centro Historico

Downtown Guadalajara, 0.8 km from San Juan de Dios
View
A modern interior with a wooden floor, a wall-mounted shelf with decorative items, and a large mirror reflecting the room.

Hotel Plaza Genova Centro

3.5 star property
Downtown Guadalajara, 0.9 km from San Juan de Dios
View
8.0
Very good
451 reviews
3.6
182 reviews
9.6
Exceptional
382 reviews
9.6
Exceptional
50 reviews
9.0
Wonderful
2,511 reviews
The price is AU$39
includes taxes & fees
13 Nov - 14 Nov
The price is AU$14
includes taxes & fees
7 Dec - 8 Dec
The price is AU$74
includes taxes & fees
15 Nov - 16 Nov
The price is AU$113
includes taxes & fees
13 Dec - 14 Dec
The price is AU$78
includes taxes & fees
17 Nov - 18 Nov
  • No Breakfast included
  • No Pool
  • No Spa
  • No Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • No Breakfast included
  • No Pool
  • No Spa
  • No Pet-friendly
  • No WiFi included
  • No Parking
  • No Breakfast included
  • No Pool
  • No Spa
  • No Pet-friendly
  • Yes, WiFi included
  • No Parking
  • No Breakfast included
  • No Pool
  • No Spa
  • No Pet-friendly
  • Yes, WiFi included
  • No Parking
  • No Breakfast included
  • No Pool
  • No Spa
  • No Pet-friendly
  • Yes, WiFi included
  • Yes, Parking

Our guide on where to stay in San Juan de Dios

Find the best San Juan de Dios areas for the activities you enjoy most. Learn more about San Juan de Dios
Learn more about San Juan de Dios
A historic cathedral with multiple spires and a large dome, surrounded by a public square with people and trees.

Downtown Guadalajara

Consider exploring the abundant dining options in Downtown Guadalajara. If sightseeing is on the list, Plaza de Armas is a top attraction. Hop on the metro at Plaza Universidad Station or Guadalajara Centro Station to see more of the area.

A classical columned structure with a dome, surrounded by greenery and a clear blue sky.

Guadalajara Centro

Double spires of the neo-Gothic cathedral rise above the central plaza beside a glorious rotunda and a majestic theater in this preserved historic district.

A historic building with a central dome and arched walkways.

Colonia Americana

If you're spending time in Colonia Americana, check out sights like Avienda Chapultepec or Templo Expiatorio del Santisimo Sacramento and hop on the metro to see more of the city at Juarez Station or Mexicaltzingo Station.

A circular water fountain with a statue in the center, surrounded by landscaped gardens and a road with vehicles.

Providencia

Providencia is popular for its abundant dining options, and if you're looking for more to see and do, you might think about a trip to Punto Sao Paulo Shopping Center or Midtown Jalisco.

A modern building with a glass facade and a sign for Expo Forestal.

Zona Expo

Zona Expo is popular for its abundant dining options, and if you're looking for more to see and do, you might think about a trip to Plaza del Sol or Galleries Theater.

Top San Juan de Dios Hotel Reviews

A hotel entrance with a stone facade, arched windows, and a central doorway.
Hotel De Mendoza

Hotel De Mendoza

Hotel De Mendoza
Downtown Guadalajara

10/10 Excellent

Gorgeous building and amazing location. The shower didn't drain and the bathroom was dated, but the room was spacious and the beds were comfortable.
Australia
Cecilia
Reviewed October 3, 2026
Hotel De Mendoza

Frequently Asked Questions

What is San Juan de Dios like?

San Juan de Dios is a neighbourhood that travellers like for its art, shopping and architecture. Make sure that you visit Hospicio Cabanas and Magno Centro Joyero as part of your San Juan de Dios travel plans.

Where is the best hotel for a stay in San Juan de Dios?

Based on our traveller data, Gran Hotel Galerias Plaza is one of the top choices for your stay in San Juan de Dios. This hotel is a short 13-minute walk from Guadalajara Cathedral, and it offers satellite TV and a 24-hour front desk.

How many hotels are there in San Juan de Dios?

Expedia has 29 hotels and other accommodation options in San Juan de Dios to choose from, making this an ideal home base for exploring the greater Guadalajara area.

If I need to cancel my hotel reservation in San Juan de Dios, will I receive a refund?

Yes! Most hotel room reservations are refundable provided that you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you have a non-refundable reservation, you may still be able to cancel and be given a refund within a 24-hour period of your booking. Add dates, click "Search", then use the filter option "fully refundable" to get top deals in San Juan de Dios.

What can I see and do in this Guadalajara neighbourhood?

If you're looking forward to a day of shopping in San Juan de Dios, consider Mercado Libertad or Magno Centro Joyero, and pick out the perfect souvenir. Hospicio Cabanas and Plaza Tapatia are some other stops worth a visit in the neighbourhood. Instituto Cultural Cabanas, Plaza de los Mariachis and Escudo de Armas are just a few of the places to visit in and around San Juan de Dios. Rincon del Diablo and Plaza Fundadores are also worth a visit when you're out sightseeing in Guadalajara.

How can I get around San Juan de Dios and the greater Guadalajara area?

Ready to get out and explore the city? San Juan de Dios Station is the closest metro station.

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