Business Hotels & Resorts in La Mesa from AU$160

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Our top choices for La Mesa business-friendly hotels

Best Western Plus La Mesa San Diego

Best Western Plus La Mesa San Diego
2.5 star property
La Mesa
8.4 out of 10, Very good, (1007)
"Nice clean place"
United States
Shawn
The price is AU$187
includes taxes & fees
5 Jan - 6 Jan 2026
Best Western Plus La Mesa San Diego

Holiday Inn Express La Mesa Near SDSU by IHG

Holiday Inn Express La Mesa Near SDSU by IHG
3.0 star property
La Mesa
8.2 out of 10, Very good, (459)
"Great Stay"
United States
Jazmin
The price is AU$243
includes taxes & fees
6 Jan - 7 Jan 2026
Holiday Inn Express La Mesa Near SDSU by IHG

Crowne Plaza San Diego - Mission Valley by IHG

Crowne Plaza San Diego - Mission Valley by IHG
3.5 star property
Mission Valley
7.8 out of 10, Good, (1013)
"Breakfast was delicious "
United States
Lukenson
The price is AU$160
includes taxes & fees
4 Jan - 5 Jan 2026
Crowne Plaza San Diego - Mission Valley by IHG

Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina
4.0 star property
Mission Bay
8.4 out of 10, Very good, (1587)
"Totally Recommend! Rooms are really clean and comfortable, the staff are great as well. "
United States
Fernando
The price is AU$301
includes taxes & fees
2 Jan - 3 Jan 2026
Hyatt Regency Mission Bay Spa and Marina

San Diego Mission Bay Resort

San Diego Mission Bay Resort
4.0 star property
Mission Bay
8.4 out of 10, Very good, (1318)
"Room was super clean and updated, location up against the bay was perfect. We really enjoyed our stay and want to come back soon!"
United States
Haley
The price is AU$314
includes taxes & fees
5 Jan - 6 Jan 2026
San Diego Mission Bay Resort

Sycuan Casino Resort

Sycuan Casino Resort
4.0 star property
El Cajon
9.2 out of 10, Wonderful, (1655)
"Very nice getaway for the family "
United States
Richard
Sycuan Casino Resort

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
3.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (1244)
"Clean, courteous staff, good location. "
United States
Carla
The price is AU$237
includes taxes & fees
2 Jan - 3 Jan 2026
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego
4.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (2890)
"Everything was great and so convenient to everywhere we wanted to go to"
United States
Julio J
The price is AU$385
includes taxes & fees
2 Jan - 3 Jan 2026
Manchester Grand Hyatt San Diego

The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection
3.0 star property
Downtown San Diego
8.8 out of 10, Excellent, (826)
"would stay again and recommend "
United States
Brendi
The price is AU$191
includes taxes & fees
4 Jan - 5 Jan 2026
The DEXTRO Little Italy, BW Premier Collection

The Guild Hotel, San Diego Downtown, a Marriott Tribute Portfolio Hotel

The Guild Hotel, San Diego Downtown, a Marriott Tribute Portfolio Hotel
4.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (1082)
"Loved my stay! Def plan to stay here again "
United States
Lizbeth Flores
The price is AU$206
includes taxes & fees
4 Jan - 5 Jan 2026
The Guild Hotel, San Diego Downtown, a Marriott Tribute Portfolio Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top La Mesa Hotel Reviews

Frequently asked questions

How much do business-friendly hotels in La Mesa cost?
Business-friendly hotels in La Mesa range between AU$160 and AU$385 per night. This means you can lock in a stay with amenities like WiFi and conference rooms at a price that fits your work budget. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
How many business-friendly hotels are there in La Mesa?
When work takes you on the road in La Mesa, there are 5 business-friendly hotels to choose from. These stays offer a suitable location with the conveniences corporate travellers need.
What are the best cheap business-friendly hotels in La Mesa?
Business-friendly hotels in La Mesa start at only AU$160 per night, so your official work trip doesn't have to cost a fortune. Hampton Inn Chula Vista Eastlake is an affordable choice that offers plenty of amenities, like pool sun loungers and a firepit. Best Western Plus Marina Gateway Hotel is another inexpensive stay that's popular with corporate guests. Conveniences here include premium bedding and hypo-allergenic bedding. If you're looking to make room for sightseeing during your La Mesa work trip, there are lots of free and popular attractions to add to your to-do list. Mingei International Museum and Computer Museum of America are visitor favourites. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What is there to do in La Mesa near my business-friendly hotel?
There are plenty of fun things that'll fill up your itinerary in La Mesa. Drop by well-known attractions like San Diego Zoo, San Diego Civic Theatre and San Diego Natural History Museum. San Diego Air and Space Museum, San Diego Museum of Art and New Childrens Museum are also on many to-do lists.

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