Top 10 Business Hotels & Accommodation in Central San Diego from AU$118 | Expedia

A red train on tracks, palm trees, and modern buildings.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check availability on Central San Diego Business Hotels

Tonight

26 Sept - 27 Sept

Tomorrow

27 Sept - 28 Sept

Next weekend

In two weeks

Our top choices for Central San Diego business-friendly hotels

A breakfast buffet area with a stone wall, a coffee station, and a fruit display.

A table with two gold-framed lamps and a vase of white flowers.

A hotel lobby with leather armchairs, a sofa, and a reception desk.

A modern hotel lobby with a fireplace, comfortable seating, and a large painting of a sunset.

1. Hampton Inn San Diego-Kearny Mesa

Kearny Mesa

United States

Paola

AU$193

includes taxes & fees

25 Oct - 26 Oct

A modern bar area with wooden ceiling beams, bar stools, and a long counter.

A hotel room with two beds, a desk, a chair, a TV, and a balcony with a view.

An outdoor seating area with wicker chairs and a fire feature.

A multi-story hotel with a curved facade, balconies, and a central entrance with a glass door.

2. Courtyard by Marriott San Diego Central

Kearny Mesa

United States

Johanna

AU$236

includes taxes & fees

27 Sept - 28 Sept

A modern hotel with a glass entrance, outdoor seating, and palm trees.

A modern hotel with a central entrance, large windows, and palm trees.

A modern living room with a fireplace, grey sofas, and a bookshelf.

A modern hotel lobby with a sofa, chairs, a coffee table, and a TV.

3. Hilton Garden Inn San Diego Mission Valley Stadium

Kearny Mesa

United States

KELLEY

AU$206

includes taxes & fees

26 Oct - 27 Oct

A pathway flanked by neatly trimmed hedges and a building with a balcony.

A courtyard with a small pond, trees, and a fountain.

A courtyard with a small pond, palm trees, and a building with balconies.

A lobby with a mosaic fountain, seating area, and a book display.

4. California Suites Hotel

Clairemont

United States

Kelly

AU$131

includes taxes & fees

29 Sept - 30 Sept

A hotel lobby with a waterfall feature, outdoor seating area, and multiple floors with balconies.

A hotel with a large pool area, outdoor seating, and a well-maintained garden.

A bar area with a long counter, multiple stools, and a television screen.

A spacious lobby with two sofas, a reception desk, and a large chandelier.

5. Crowne Plaza San Diego - Mission Valley by IHG

Mission Valley

United States

Athir

AU$187

includes taxes & fees

5 Oct - 6 Oct

An outdoor patio with a stone fire pit, outdoor seating, string lights, and a tall, narrow heater.

A swimming pool with a visible water filtration system and a tiled edge.

A hotel room with a large bed, a chair, a nightstand, and a lamp.

A multi-level hotel lobby with dining areas, a reception desk, and a large TV screen.

6. Embassy Suites by Hilton San Diego La Jolla

University City

United States

Virginia

AU$345

includes taxes & fees

2 Oct - 3 Oct

A spacious lobby with a high ceiling, modern furniture, and a fireplace.

An outdoor dining area with tables and chairs, a fountain with dolphin sculptures, and a modern building in the background.

A modern building with a reflective glass facade, surrounded by palm trees and a pool with dolphin sculptures.

A spacious lobby with a high ceiling, a fireplace, modern seating, and large windows offering a view of greenery.

7. Four Points by Sheraton San Diego

Kearny Mesa

United States

Nikkia

AU$221

includes taxes & fees

29 Sept - 30 Sept

An outdoor seating area with wicker chairs and a fire pit, surrounded by palm trees and string lights.

A modern dining area with a large table, chairs, and hanging plants.

A spacious lobby with a central seating area, a staircase, and a view of the hallway leading to the entrance.

A poolside area with a concrete pool, lounge chairs, and a wooden deck.

8. DoubleTree by Hilton Hotel San Diego - Mission Valley

Mission Valley

Canada

Allison

AU$213

includes taxes & fees

27 Sept - 28 Sept

View all properties

Top Central San Diego Hotel Reviews

Town and Country San Diego

Town and Country San Diego

10/10 Excellent

"All the great amenities"

Crowne Plaza San Diego - Mission Valley by IHG

Crowne Plaza San Diego - Mission Valley by IHG

10/10 Excellent

"As expected. Thank you for a great stay"

DoubleTree by Hilton Hotel San Diego - Mission Valley

DoubleTree by Hilton Hotel San Diego - Mission Valley

10/10 Excellent

"was such a good stay! staff checked on us when we ran into a situation which was nice!"

Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle

10/10 Excellent

"The staff was very helpful and friendly. Our room was clean and comfortable. It was also quiet."

California Suites Hotel

California Suites Hotel

10/10 Excellent

"I had the best time a much needed mini vacation 🥰😌🌴🏖️☀️❤️ I look forward to doing it again soon 🙌"

Best Western Inn & Suites San Diego – Zoo/SeaWorld Area

Best Western Inn & Suites San Diego – Zoo/SeaWorld Area

8/10 Good

"It was good"

The Alcala Hotel Mission Valley/Seaworld

The Alcala Hotel Mission Valley/Seaworld

10/10 Excellent

"I stayed here years ago, and the property has definitely been upgraded. The staff is great too! Raul and Fermin, thanks for all of the help. The continental breakfast is a nice touch too."

Explore a world of travel with Expedia

Book Business Hotels in Central San Diego on Expedia.com