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Cheap Flights from Quito (UIO) to Santiago (SCL)

View AU$334 flight on Sun, 6 Sept 2026Opens in a new window

Popular airlines from Mariscal Sucre Intl. Airport (UIO) to Santiago Intl. Airport (SCL)

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Cheap Flights from Quito (UIO) to Santiago (SCL)

Prices were available within the past 7 days for one-way flights and round trip tickets for the period specified. Prices and availability are subject to change. Additional terms apply.

LATAM Airlines Group
Sun, 27 Sept - Wed, 30 Sept
UIO
Quito
SCL
Santiago
AU$608 Return, found 4 hours ago
AU$608
Return
found 4 hours ago
Select LATAM Airlines Group flight, departing Sun, 27 Sept from Quito to Santiago, returning Wed, 30 Sept, priced at AU$608 found 4 hours ago
LATAM Airlines Group
Sun, 27 Sept - Wed, 30 Sept
UIO
Quito
SCL
Santiago
AU$634 Return, found 4 hours ago
AU$634
Return
found 4 hours ago
Select LATAM Airlines Group flight, departing Sun, 27 Sept from Quito to Santiago, returning Wed, 30 Sept, priced at AU$634 found 4 hours ago
LATAM Airlines Group
Sun, 27 Sept - Wed, 30 Sept
UIO
Quito
SCL
Santiago
AU$665 Return, found 4 hours ago
AU$665
Return
found 4 hours ago
Select LATAM Airlines Group flight, departing Sun, 27 Sept from Quito to Santiago, returning Wed, 30 Sept, priced at AU$665 found 4 hours ago
LATAM Airlines Group
Sun, 27 Sept - Wed, 30 Sept
UIO
Quito
SCL
Santiago
AU$669 Return, found 4 hours ago
AU$669
Return
found 4 hours ago
Select LATAM Airlines Group flight, departing Sun, 27 Sept from Quito to Santiago, returning Wed, 30 Sept, priced at AU$669 found 4 hours ago
Jetsmart SPA
Fri, 11 Sept - Fri, 18 Sept
UIO
Quito
SCL
Santiago
AU$674 Return, found 4 days ago
AU$674
Return
found 4 days ago
Select Jetsmart SPA flight, departing Fri, 11 Sept from Quito to Santiago, returning Fri, 18 Sept, priced at AU$674 found 4 days ago
LATAM Airlines Group
Sun, 27 Sept - Wed, 30 Sept
UIO
Quito
SCL
Santiago
AU$680 Return, found 4 hours ago
AU$680
Return
found 4 hours ago
Select LATAM Airlines Group flight, departing Sun, 27 Sept from Quito to Santiago, returning Wed, 30 Sept, priced at AU$680 found 4 hours ago
Jetsmart SPA
Fri, 23 Oct - Fri, 30 Oct
UIO
Quito
SCL
Santiago
AU$687 Return, found 5 days ago
AU$687
Return
found 5 days ago
Select Jetsmart SPA flight, departing Fri, 23 Oct from Quito to Santiago, returning Fri, 30 Oct, priced at AU$687 found 5 days ago
avianca
Wed, 9 Sept - Wed, 30 Sept
UIO
Quito
SCL
Santiago
AU$813 Return, found 6 days ago
AU$813
Return
found 6 days ago
Select avianca flight, departing Wed, 9 Sept from Quito to Santiago, returning Wed, 30 Sept, priced at AU$813 found 6 days ago
Copa
Wed, 9 Sept - Wed, 30 Sept
UIO
Quito
SCL
Santiago
AU$820 Return, found 6 days ago
AU$820
Return
found 6 days ago
Select Copa flight, departing Wed, 9 Sept from Quito to Santiago, returning Wed, 30 Sept, priced at AU$820 found 6 days ago
Aerolineas Argentinas
Thu, 1 Apr - Sun, 2 May
UIO
Quito
SCL
Santiago
AU$1,518 Return, found 3 days ago
AU$1,518
Return
found 3 days ago
Select Aerolineas Argentinas flight, departing Thu, 1 Apr from Quito to Santiago, returning Sun, 2 May, priced at AU$1,518 found 3 days ago

Frequently asked questions

How much does a flight from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez) cost?
You can find one-way and return flights from UIO to SCL with Expedia. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see our cheapest fares first, and use the Price Tracking tool to receive alerts when UIO to SCL ticket fares go up or down.
What is the cheapest month to fly from Quito (UIO) to Santiago (SCL)?
The cheapest months to fly from Quito (UIO) to Santiago (SCL) are typically during off-peak season when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you are able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Quito (UIO) to Santiago (SCL)?
Enter UIO to SCL and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez)?
LATAM Airlines Group is one of the cheapest airlines offering connecting return flights from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez), with prices starting from around AU$727 for flights that can be booked for departure within the next year, with a layover in El Dorado Intl. (BOG). These prices are per adult, for economy/coach class. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.
How do I find cheap flights from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez)?
To find a cheap flight from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Quito (UIO) to Santiago (SCL)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
How many flights per day from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez)?
There are approximately 28 connecting flights per day from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez). Some common connection points include Jose Joaquin de Olmedo Intl. (GYE), Tocumen Intl. (PTY), and Jorge Chavez Intl. (LIM).
What is the earliest flight from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez)?
The earliest flight from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez) typically departs around 12:00 AM local time. This service is operated by LATAM Airlines Group and is a seasonal offering, active only in April. An early departure like this can be great for maximizing your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez)?
You'll generally find the most flights from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez) on a Wednesday, with around 22 flights available. This gives you a good selection for your travel plans. Major airlines on this route include LATAM Airlines Group, Avianca, and Copa. Looking at the week, Wednesday offers notably more flight options compared to other days, ensuring you have plenty of choices.
What are the most popular departure times for flights from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez)?
The most popular departure times for flights from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez) are in the evening, from 6pm to 9pm. Many major carriers, including Copa, LATAM Airlines Group and Avianca, offer flights during this window. Many travellers prefer this time as it allows you to finish your day in Quito and arrive in Santiago later in the evening.
How long does it take to fly from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez)?
There are no nonstop flights from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez). The distance between these two cities is approximately 3783 kilometres. Flights with one stop typically take around 16 hours 30 minutes. If you opt for flights with two or more stops, your travel time will be longer, usually around 24 hours 30 minutes. Keep in mind that actual flight times can vary due to factors like routing, weather, and wind patterns.
Can you fly business or first class from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez)?
Yes, you can fly business class between UIO and SCL. Airlines that offer business class service on this route include:
  • Copa
  • Avianca
  • United
How do I earn miles on a Quito (UIO) to Santiago (SCL) flight with Expedia?
It's easy to earn miles on a Quito (UIO) to Santiago (SCL) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Santiago (SCL) from Quito (UIO)?
If you're planning to travel to Santiago from Mariscal Sucre Intl. (UIO), you can fly directly into Arturo Merino Benitez (SCL). Some flights may connect through major hubs like Jose Joaquin de Olmedo Intl. (GYE), Jorge Chavez Intl. (LIM), or El Dorado Intl. (BOG) before reaching Santiago. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Quito (UIO) to Santiago (SCL) at the last minute?
Typically, booking a last minute flight from Quito (UIO) to Santiago (SCL) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Quito (UIO) to Santiago (SCL) flight and hotel package?
Securing a Quito (UIO) to Santiago (SCL) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez)?
If you booked your Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Mariscal Sucre Intl.
Destination airport
Arturo Merino Benitez
Airlines serving
Copa, Jetsmart SPA, LATAM Airlines Group, avianca
Roundtrip price
AU$607
Distance
3761 km

Book with confidence

Your quick guide to flights from Quito to Santiago

Pick up great flights from Quito to Santiago

With Expedia, you have your pick of flights a day with 20 airlines covering flights from Quito to Santiago. Whether you’re on a business trip, a family holiday or a luxury break, just enter your travel dates, hit search then check out your choice of flights. Select from return, one way or multi-city flights, and use the advance search tool if you want a direct or refundable flight. You can narrow your search to show you just your preferred cabin class and airline, too. It’s all easy. You can book direct flights from Quito to Santiago that take around hours.

Find cheap flights from Quito to Santiago

From the great flight deals with prices currently ranging from AU$608 to AU$1,518, you can choose to see the cheapest flights first. Generally, you can book the cheapest flights from Quito to Santiago around 4 to 6 weeks in advance. If your travel dates are flexible, try to avoid weekends and peak seasons – when you are more likely to grab the lowest prices. Even last minute, there are some impressive deals. The cheapest time to fly to Santiago is normally in September.

Reasons to book your flight from Quito to Santiago with Expedia

Expedia makes it easy to find, book, and travel, with everything you need all in one place. When you enter your travel details, find fantastic deals just for you on flight tickets from Quito to Santiago across all the main airline carriers, so you can save time, dollars, and hassle finding the perfect flight. If you think your plans could change, choose refundable flights so any changes won’t cost you more. Book your flight to Santiago right now and, if you join Expedia Rewards, you earn points this time and every time you travel with Expedia.

Your quick guide to flights from Quito to Santiago

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