Cheap Flights from Manaus (MAO) to Santiago (SCL)

View AU$325 flight on Thu, 9 Apr. 2026Opens in a new window

Popular airlines from Manaus (MAO-Eduardo Gomes Intl.) to Santiago Intl. Airport (SCL)

  • Plan, book, fly with confidence

  • trending down icon

    Be in the know

    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon

    Book smarter

    Save up to 35% on select hotels after you book a flight*
  • payments icon

    Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Cheap Flights from Manaus (MAO) to Santiago (SCL)

Prices were available within the past 7 days for one-way flights and round trip tickets for the period specified. Prices and availability are subject to change. Additional terms apply.

Flight from Manaus to Santiago route information
Origin airport
Eduardo Gomes Intl.
Destination airport
Arturo Merino Benitez
Distance
3535 km

Your quick guide to flights from Manaus to Santiago

Pick up great flights from Manaus to Santiago

With Expedia, you have your pick of flights a day with 20 airlines covering flights from Manaus to Santiago. Whether you’re on a business trip, a family holiday or a luxury break, just enter your travel dates, hit search then check out your choice of flights. Select from return, one way or multi-city flights, and use the advance search tool if you want a direct or refundable flight. You can narrow your search to show you just your preferred cabin class and airline, too. It’s all easy. You can book direct flights from Manaus to Santiago that take around hours.

Find cheap flights from Manaus to Santiago

From the great flight deals with prices currently ranging from to , you can choose to see the cheapest flights first. Generally, you can book the cheapest flights from Manaus to Santiago around 4 to 6 weeks in advance. If your travel dates are flexible, try to avoid weekends and peak seasons – when you are more likely to grab the lowest prices. Even last minute, there are some impressive deals. The cheapest time to fly to Santiago is normally in .

Reasons to book your flight from Manaus to Santiago with Expedia

Expedia makes it easy to find, book, and travel, with everything you need all in one place. When you enter your travel details, find fantastic deals just for you on flight tickets from Manaus to Santiago across all the main airline carriers, so you can save time, dollars, and hassle finding the perfect flight. If you think your plans could change, choose refundable flights so any changes won’t cost you more. Book your flight to Santiago right now and, if you join Expedia Rewards, you earn points this time and every time you travel with Expedia.

Frequently asked questions

How much is a flight from MAO to Nuevo Pudahuel Airport?
Round-trip tickets between Eduardo Gomes Intl. Airport (MAO) and Nuevo Pudahuel Airport start from . This figure is based on fares quoted within the last 7 days on Expedia for flights departing within the next year — book today so you don't miss out. Prices and availability are subject to change. Additional terms apply.
Do I need to pay a cancellation fee if I cancel my flight from MAO to Santiago International Airport?
Each air carrier has its own set of terms and conditions. If you do decide to cancel, follow the instructions on our Customer Service Portal.
How do I find cheap flights from Manaus Intl. Airport – Eduardo Gomes to SCL that have flexible change policies?
Many airlines offer the option to reschedule your flight without a change fee. All you pay is the difference between the original flight and the new flight. When you're searching for MAO to Nuevo Pudahuel Airport flights, you'll see a "no change fees" filter for you to select.
How far is the flight from Eduardo Gomes Intl. Airport (MAO) to Santiago International Airport?
The flight distance from Manaus to Santiago is 3 600 kilometres. Bring a drink, a snack and an interesting book to read. Keep yourself occupied and the hours will zip by.
Which airlines fly direct from MAO to Santiago International Airport?
Unfortunately, there aren't any airlines that fly direct between Manaus Intl. Airport – Eduardo Gomes and SCL. You'll need to book a flight with one or more stops.
Are MAO to Arturo Merino Benitez Airport (SCL) flight tickets cheaper when they're purchased at the last minute?
Flight prices go up and down like a yo-yo, so there are no guarantees. While last-minute deals between Manaus Intl. Airport – Eduardo Gomes and SCL are of course possible, it's also a good idea to keep an eye on prices well before you fly. In fact, some airlines advertise their prices up to 12 months prior to the departure date. Expedia is continuously updating the best airfare bargains around, so keep checking and be ready to lock in your seat when the price dips.

Explore a world of travel with Expedia

*Available to Expedia members.