Cheap Flights from Cusco (CUZ) to Santiago (SCL)

View AU$209 flight on Fri, 21 Nov. 2025Opens in a new window

Popular airlines from Alejandro Velasco Astete Intl. Airport (CUZ) to Santiago Intl. Airport (SCL)

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Cheap Flights from Cusco (CUZ) to Santiago (SCL)

Prices were available within the past 7 days for one-way flights and round trip tickets for the period specified. Prices and availability are subject to change. Additional terms apply.

LATAM Airlines Group
Thu, 20 Nov. - Wed, 26 Nov.
CUZ
Cusco
SCL
Santiago
AU$496 Return, found 4 hours ago
AU$496
Return
found 4 hours ago
Select LATAM Airlines Group flight, departing Thu, 20 Nov. from Cusco to Santiago, returning Wed, 26 Nov., priced at AU$496 found 4 hours ago
LATAM Airlines Group
Thu, 20 Nov. - Wed, 26 Nov.
CUZ
Cusco
SCL
Santiago
AU$511 Return, found 4 hours ago
AU$511
Return
found 4 hours ago
Select LATAM Airlines Group flight, departing Thu, 20 Nov. from Cusco to Santiago, returning Wed, 26 Nov., priced at AU$511 found 4 hours ago
LATAM Airlines Group
Sat, 9 Aug. - Mon, 18 Aug.
CUZ
Cusco
SCL
Santiago
AU$526 Return, found 2 days ago
AU$526
Return
found 2 days ago
Select LATAM Airlines Group flight, departing Sat, 9 Aug. from Cusco to Santiago, returning Mon, 18 Aug., priced at AU$526 found 2 days ago
LATAM Airlines Group
Fri, 9 Jan. - Wed, 21 Jan.
CUZ
Cusco
SCL
Santiago
AU$528 Return, found 4 days ago
AU$528
Return
found 4 days ago
Select LATAM Airlines Group flight, departing Fri, 9 Jan. from Cusco to Santiago, returning Wed, 21 Jan., priced at AU$528 found 4 days ago
SKY AIRLINE
Thu, 20 Nov. - Wed, 26 Nov.
CUZ
Cusco
SCL
Santiago
AU$531 Return, found 4 hours ago
AU$531
Return
found 4 hours ago
Select SKY AIRLINE flight, departing Thu, 20 Nov. from Cusco to Santiago, returning Wed, 26 Nov., priced at AU$531 found 4 hours ago
LATAM Airlines Group
Sat, 9 Aug. - Mon, 18 Aug.
CUZ
Cusco
SCL
Santiago
AU$537 Return, found 2 days ago
AU$537
Return
found 2 days ago
Select LATAM Airlines Group flight, departing Sat, 9 Aug. from Cusco to Santiago, returning Mon, 18 Aug., priced at AU$537 found 2 days ago
LATAM Airlines Group
Fri, 9 Jan. - Wed, 21 Jan.
CUZ
Cusco
SCL
Santiago
AU$540 Return, found 4 days ago
AU$540
Return
found 4 days ago
Select LATAM Airlines Group flight, departing Fri, 9 Jan. from Cusco to Santiago, returning Wed, 21 Jan., priced at AU$540 found 4 days ago
LATAM Airlines Group
Thu, 20 Nov. - Wed, 26 Nov.
CUZ
Cusco
SCL
Santiago
AU$543 Return, found 4 hours ago
AU$543
Return
found 4 hours ago
Select LATAM Airlines Group flight, departing Thu, 20 Nov. from Cusco to Santiago, returning Wed, 26 Nov., priced at AU$543 found 4 hours ago
LATAM Airlines Group
Fri, 10 Oct. - Thu, 16 Oct.
CUZ
Cusco
SCL
Santiago
AU$544 Return, found 14 hours ago
AU$544
Return
found 14 hours ago
Select LATAM Airlines Group flight, departing Fri, 10 Oct. from Cusco to Santiago, returning Thu, 16 Oct., priced at AU$544 found 14 hours ago
LATAM Airlines Group
Fri, 24 Oct. - Mon, 27 Oct.
CUZ
Cusco
SCL
Santiago
AU$547 Return, found 4 days ago
AU$547
Return
found 4 days ago
Select LATAM Airlines Group flight, departing Fri, 24 Oct. from Cusco to Santiago, returning Mon, 27 Oct., priced at AU$547 found 4 days ago

Find the cheapest month to fly from Cusco (CUZ) to Santiago (SCL)

November is typically the cheapest month to fly

From AU$334 - AU$672 per traveller.

Graph displaying average flight prices per month

Flight from Cusco to Santiago route information
Origin airport
Alejandro Velasco Astete Intl.
Destination airport
Arturo Merino Benitez
Airlines serving
LATAM Airlines Group, SKY AIRLINE
Return price
AU$496
Distance
2198 km
Average flight time
2 hours 20 mins

Your quick guide to flights from Cusco to Santiago

Pick up great flights from Cusco to Santiago

With Expedia, you have your pick of 1 flights a day with 20 airlines covering flights from Cusco to Santiago. Whether you’re on a business trip, a family holiday or a luxury break, just enter your travel dates, hit search then check out your choice of flights. Select from return, one way or multi-city flights, and use the advance search tool if you want a direct or refundable flight. You can narrow your search to show you just your preferred cabin class and airline, too. It’s all easy. You can book direct flights from Cusco to Santiago that take around 3 hours.

Find cheap flights from Cusco to Santiago

From the great flight deals with prices currently ranging from AU$496 to AU$547, you can choose to see the cheapest flights first. Generally, you can book the cheapest flights from Cusco to Santiago around 4 to 6 weeks in advance. If your travel dates are flexible, try to avoid weekends and peak seasons – when you are more likely to grab the lowest prices. Even last minute, there are some impressive deals. The cheapest time to fly to Santiago is normally in November.

Reasons to book your flight from Cusco to Santiago with Expedia

Expedia makes it easy to find, book, and travel, with everything you need all in one place. When you enter your travel details, find fantastic deals just for you on flight tickets from Cusco to Santiago across all the main airline carriers, so you can save time, dollars, and hassle finding the perfect flight. If you think your plans could change, choose refundable flights so any changes won’t cost you more. Book your flight to Santiago right now and, if you join Expedia Rewards, you earn points this time and every time you travel with Expedia.

Frequently asked questions

How much is a flight from Alejandro Velasco Astete Intl. Airport (CUZ) to SCL?
Start packing your bags, because round-trip journeys between CUZ and Nuevo Pudahuel Airport start from AU$496. That's based on fares advertised within the last 7 days on Expedia for flights departing within the next year. Prices can go up quickly, so book now to score the best deal. Prices and availability are subject to change. Additional terms apply.
Do I need to pay a cancellation fee if I cancel my flight from CUZ to Arturo Merino Benitez Airport (SCL)?
Each air carrier has its own set of terms and conditions. If you do decide to cancel, follow the instructions on our Customer Service Portal.
How do I find cheap flights from CUZ to Santiago International Airport that have flexible change policies?
Many airlines offer the option to reschedule your flight without a change fee. All you pay is the difference between the original flight and the new flight. When you're searching for Alejandro Velasco Astete Intl. Airport (CUZ) to Nuevo Pudahuel Airport flights, you'll see a "no change fees" filter for you to select.
How far is the flight from CUZ to Arturo Merino Benitez Airport (SCL)?
You'll be soaring through the sky for a while, as the flight distance from Cusco to Santiago is 2 200 kilometres. Create a playlist of your favourite tunes before leaving home to stay entertained during your trip.
Which airlines fly direct from Alejandro Velasco Astete Intl. Airport (CUZ) to SCL?
LATAM Airlines (LA) will take you from CUZ to Nuevo Pudahuel Airport safely and reliably. Take your pick of 13 flights each month on this route.
Are CUZ to SCL flight tickets cheaper when they're purchased at the last minute?
Booking your trip from Alejandro Velasco Astete Intl. Airport (CUZ) to Arturo Merino Benitez Airport (SCL) at the last minute could be your ticket to a fantastic deal. However, it could end up costing you a whole lot more! If you'd prefer to err on the side of caution, book well ahead of your departure date. In fact, Expedia has some of the best bargains up to 12 months in advance. If your preferred carrier hasn't released tickets yet, check back frequently as deals are updated on Expedia all the time.

Explore a world of travel with Expedia

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