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Cheap Flights from Panama City (PTY) to Santiago (SCL)

View AU$530 flight on Thu, 11 Feb 2027Opens in a new window

Popular airlines from Tocumen Intl. Airport (PTY) to Santiago Intl. Airport (SCL)

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Cheap Flights from Panama City (PTY) to Santiago (SCL)

Prices were available within the past 7 days for one-way flights and round trip tickets for the period specified. Prices and availability are subject to change. Additional terms apply.

avianca
Wed, 9 Dec - Thu, 11 Feb
PTY
Panama City
SCL
Santiago
AU$962 Return, found 5 hours ago
AU$962
Return
found 5 hours ago
Select avianca flight, departing Wed, 9 Dec from Panama City to Santiago, returning Thu, 11 Feb, priced at AU$962 found 5 hours ago
avianca
Wed, 25 Nov - Wed, 2 Dec
PTY
Panama City
SCL
Santiago
AU$966 Return, found 1 day ago
AU$966
Return
found 1 day ago
Select avianca flight, departing Wed, 25 Nov from Panama City to Santiago, returning Wed, 2 Dec, priced at AU$966 found 1 day ago
avianca
Fri, 16 Oct - Tue, 24 Nov
PTY
Panama City
SCL
Santiago
AU$997 Return, found 5 days ago
AU$997
Return
found 5 days ago
Select avianca flight, departing Fri, 16 Oct from Panama City to Santiago, returning Tue, 24 Nov, priced at AU$997 found 5 days ago
avianca
Wed, 9 Dec - Thu, 11 Feb
PTY
Panama City
SCL
Santiago
AU$1,020 Return, found 5 hours ago
AU$1,020
Return
found 5 hours ago
Select avianca flight, departing Wed, 9 Dec from Panama City to Santiago, returning Thu, 11 Feb, priced at AU$1,020 found 5 hours ago
avianca
Wed, 25 Nov - Wed, 2 Dec
PTY
Panama City
SCL
Santiago
AU$1,024 Return, found 1 day ago
AU$1,024
Return
found 1 day ago
Select avianca flight, departing Wed, 25 Nov from Panama City to Santiago, returning Wed, 2 Dec, priced at AU$1,024 found 1 day ago
avianca
Wed, 25 Nov - Wed, 2 Dec
PTY
Panama City
SCL
Santiago
AU$1,040 Return, found 1 day ago
AU$1,040
Return
found 1 day ago
Select avianca flight, departing Wed, 25 Nov from Panama City to Santiago, returning Wed, 2 Dec, priced at AU$1,040 found 1 day ago
avianca
Wed, 9 Dec - Thu, 11 Feb
PTY
Panama City
SCL
Santiago
AU$1,043 Return, found 5 hours ago
AU$1,043
Return
found 5 hours ago
Select avianca flight, departing Wed, 9 Dec from Panama City to Santiago, returning Thu, 11 Feb, priced at AU$1,043 found 5 hours ago
Copa
Tue, 13 Oct - Sat, 21 Nov
PTY
Panama City
SCL
Santiago
AU$1,050 Return, found 5 days ago
AU$1,050
Return
found 5 days ago
Select Copa flight, departing Tue, 13 Oct from Panama City to Santiago, returning Sat, 21 Nov, priced at AU$1,050 found 5 days ago
Aeromexico
Wed, 25 Nov - Wed, 2 Dec
PTY
Panama City
SCL
Santiago
AU$1,309 Return, found 1 day ago
AU$1,309
Return
found 1 day ago
Select Aeromexico flight, departing Wed, 25 Nov from Panama City to Santiago, returning Wed, 2 Dec, priced at AU$1,309 found 1 day ago
American Airlines
Wed, 9 Dec - Thu, 11 Feb
PTY
Panama City
SCL
Santiago
AU$2,256 Return, found 5 hours ago
AU$2,256
Return
found 5 hours ago
Select American Airlines flight, departing Wed, 9 Dec from Panama City to Santiago, returning Thu, 11 Feb, priced at AU$2,256 found 5 hours ago

Find the cheapest month to fly from Panama City (PTY) to Santiago (SCL)

February is typically the cheapest month to fly

From AU$670 - AU$1,052 per traveller.

Frequently asked questions

How much does a flight from Panama City (PTY-Tocumen Intl.) to Santiago (SCL-Arturo Merino Benitez) cost?
You can find one-way and return flights from PTY to SCL with Expedia. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see our cheapest fares first, and use the Price Tracking tool to receive alerts when PTY to SCL ticket fares go up or down.
What is the cheapest month to fly from Panama City (PTY-Tocumen Intl.) to Santiago (SCL-Arturo Merino Benitez)?
The cheapest months to fly from PTY to SCL are typically during off-peak season when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you are able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Panama City (PTY-Tocumen Intl.) to Santiago (SCL-Arturo Merino Benitez)?
Only one airline offers direct flights from Panama City (PTY-Tocumen Intl.) to Santiago (SCL-Arturo Merino Benitez). Copa operates 40 direct flights from Panama City (PTY-Tocumen Intl.) to Santiago (SCL-Arturo Merino Benitez) every week.
How do I find cheap flights from Panama City (PTY) to Santiago (SCL)?
To find a cheap flight from Panama City (PTY) to Santiago (SCL), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best airline to fly with from Panama City (PTY-Tocumen Intl.) to Santiago (SCL-Arturo Merino Benitez)?
The best airline to fly with from Panama City (PTY-Tocumen Intl.) to Santiago (SCL-Arturo Merino Benitez) will differ from traveler to traveler. If you like to fly early, Copa offers early morning flights. If price is the most important factor, Copa typically offers the lowest fares. Avianca offers the most daily flights from Panama City (PTY-Tocumen Intl.) to Santiago (SCL-Arturo Merino Benitez), which is great if flexibility is what you value most. The best carrier for this journey could also be the one you have a loyalty membership with, as flying with that airline or another airline within the same alliance could help you collect points or enjoy lounge access.
What is the best time to fly from Panama City (PTY-Tocumen Intl.) to Santiago (SCL-Arturo Merino Benitez)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
How many flights per day from Panama City (PTY-Tocumen Intl.) to Santiago (SCL-Arturo Merino Benitez)?
You'll find around 5 nonstop flights per day from Panama City (PTY-Tocumen Intl.) to Santiago (SCL-Arturo Merino Benitez). For even more choices, look at flights that include layovers, as there are approximately 8 connecting flights per day. Some common connection points include El Dorado Intl. (BOG), El Salvador Intl. (SAL), and Juan Santamaria Intl. (SJO).
What is the earliest flight from Panama City (PTY-Tocumen Intl.) to Santiago (SCL-Arturo Merino Benitez)?
The earliest flight from Panama City (PTY-Tocumen Intl.) to Santiago (SCL-Arturo Merino Benitez) typically departs around 2:55 AM. This flight is operated by Avianca. This is a seasonal service, active in January, February, March, October, November, and December. An early departure like this can help you make the most of your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Panama City (PTY-Tocumen Intl.) to Santiago (SCL-Arturo Merino Benitez)?
You'll typically find the most flights from Panama City (PTY-Tocumen Intl.) to Santiago (SCL-Arturo Merino Benitez) on a Thursday, with around 12 flights available. This gives you a good selection of options for your travel plans. Major airlines on this route include Copa, Avianca, and American Airlines. Flight schedules are quite consistent throughout the week, so you'll have plenty of choices no matter when you plan to fly.
What are the most popular departure times for flights from Panama City (PTY-Tocumen Intl.) to Santiago (SCL-Arturo Merino Benitez)?
The most popular departure times for flights from Panama City (PTY-Tocumen Intl.) to Santiago (SCL-Arturo Merino Benitez) are in the afternoon, from 3pm to 6pm. Many major carriers, including Avianca, Copa and American Airlines, offer flights during this window. Many travelers prefer this because it allows for a productive morning before heading to the airport and an evening arrival at your destination.
How long does it take to fly from Panama City (PTY-Tocumen Intl.) to Santiago (SCL-Arturo Merino Benitez)?
A nonstop flight from Panama City (PTY-Tocumen Intl.) to Santiago (SCL-Arturo Merino Benitez) typically takes around 6 hours 30 minutes. This route covers a distance of approximately 4809 kilometres. If you opt for a one-stop flight, your travel time will be longer, usually around 9 hours 50 minutes. Flights with two or more stops generally take about 16 hours 18 minutes. Keep in mind that actual flight times can vary due to factors like wind patterns and air traffic, so it's always a good idea to allow for some extra time when planning your trip.
Can you fly business or first class from Panama City (PTY-Tocumen Intl.) to Santiago (SCL-Arturo Merino Benitez)?
You can fly business class between PTY and SCL. Airlines that offer business class service on this route include:
  • Copa
  • Avianca
  • Aeromexico
  • American Airlines
  • United
How do I earn miles on a Panama City (PTY) to Santiago (SCL) flight with Expedia?
It's easy to earn miles on a Panama City (PTY) to Santiago (SCL) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Santiago (SCL) from Panama City (PTY)?
If you're planning to travel to Santiago from Tocumen Intl. (PTY), you can fly directly into Arturo Merino Benitez (SCL). Some flights may connect through major hubs like Galeao - Antonio Carlos Jobim Intl. (GIG) before reaching Santiago. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Panama City (PTY) to Santiago (SCL) at the last minute?
Typically, booking a last minute flight from Panama City (PTY) to Santiago (SCL) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Panama City (PTY) to Santiago (SCL) flight and hotel package?
Securing a Panama City (PTY) to Santiago (SCL) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Panama City (PTY) to Santiago (SCL)?
If you booked your Panama City (PTY) to Santiago (SCL) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Tocumen Intl.
Destination airport
Arturo Merino Benitez
Airlines serving
Aeromexico, American Airlines, Copa, avianca
Return price
AU$961
Distance
4780 km
Average flight time
7 hours 35 mins

Book with confidence

Your quick guide to flights from Panama City to Santiago

Pick up great flights from Panama City to Santiago

With Expedia, you have your pick of flights a day with 20 airlines covering flights from Panama City to Santiago. Whether you’re on a business trip, a family holiday or a luxury break, just enter your travel dates, hit search then check out your choice of flights. Select from return, one way or multi-city flights, and use the advance search tool if you want a direct or refundable flight. You can narrow your search to show you just your preferred cabin class and airline, too. It’s all easy. You can book direct flights from Panama City to Santiago that take around hours.

Find cheap flights from Panama City to Santiago

From the great flight deals with prices currently ranging from AU$962 to AU$2,791, you can choose to see the cheapest flights first. Generally, you can book the cheapest flights from Panama City to Santiago around 4 to 6 weeks in advance. If your travel dates are flexible, try to avoid weekends and peak seasons – when you are more likely to grab the lowest prices. Even last minute, there are some impressive deals. The cheapest time to fly to Santiago is normally in December.

Reasons to book your flight from Panama City to Santiago with Expedia

Expedia makes it easy to find, book, and travel, with everything you need all in one place. When you enter your travel details, find fantastic deals just for you on flight tickets from Panama City to Santiago across all the main airline carriers, so you can save time, dollars, and hassle finding the perfect flight. If you think your plans could change, choose refundable flights so any changes won’t cost you more. Book your flight to Santiago right now and, if you join Expedia Rewards, you earn points this time and every time you travel with Expedia.

Your quick guide to flights from Panama City to Santiago

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*Available to Expedia members.