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Cheap Flights from Guayaquil (GYE) to Santiago (SCL)

View AU$315 flight on Tue, 1 June 2027Opens in a new window

Flight 1

Popular airlines from Jose Joaquin de Olmedo Intl. Airport (GYE) to Santiago Intl. Airport (SCL)

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Cheap Flights from Guayaquil (GYE) to Santiago (SCL)

Prices were available within the past 7 days for one-way flights and round trip tickets for the period specified. Prices and availability are subject to change. Additional terms apply.

avianca
Mon, 15 Feb - Fri, 19 Feb
GYE
Guayaquil
SCL
Santiago
AU$632 Return, found 5 hours ago
AU$632
Return
found 5 hours ago
Select avianca flight, departing Mon, 15 Feb from Guayaquil to Santiago, returning Fri, 19 Feb, priced at AU$632 found 5 hours ago
LATAM Airlines Group
Mon, 15 Feb - Fri, 19 Feb
GYE
Guayaquil
SCL
Santiago
AU$638 Return, found 5 hours ago
AU$638
Return
found 5 hours ago
Select LATAM Airlines Group flight, departing Mon, 15 Feb from Guayaquil to Santiago, returning Fri, 19 Feb, priced at AU$638 found 5 hours ago
LATAM Airlines Group
Mon, 15 Feb - Fri, 19 Feb
GYE
Guayaquil
SCL
Santiago
AU$647 Return, found 5 hours ago
AU$647
Return
found 5 hours ago
Select LATAM Airlines Group flight, departing Mon, 15 Feb from Guayaquil to Santiago, returning Fri, 19 Feb, priced at AU$647 found 5 hours ago
LATAM Airlines Group
Mon, 15 Feb - Fri, 19 Feb
GYE
Guayaquil
SCL
Santiago
AU$656 Return, found 5 hours ago
AU$656
Return
found 5 hours ago
Select LATAM Airlines Group flight, departing Mon, 15 Feb from Guayaquil to Santiago, returning Fri, 19 Feb, priced at AU$656 found 5 hours ago
LATAM Airlines Group
Tue, 4 Aug - Tue, 18 Aug
GYE
Guayaquil
SCL
Santiago
AU$666 Return, found 2 days ago
AU$666
Return
found 2 days ago
Select LATAM Airlines Group flight, departing Tue, 4 Aug from Guayaquil to Santiago, returning Tue, 18 Aug, priced at AU$666 found 2 days ago
avianca
Mon, 15 Feb - Fri, 19 Feb
GYE
Guayaquil
SCL
Santiago
AU$677 Return, found 5 hours ago
AU$677
Return
found 5 hours ago
Select avianca flight, departing Mon, 15 Feb from Guayaquil to Santiago, returning Fri, 19 Feb, priced at AU$677 found 5 hours ago
avianca
Mon, 15 Feb - Fri, 19 Feb
GYE
Guayaquil
SCL
Santiago
AU$681 Return, found 5 hours ago
AU$681
Return
found 5 hours ago
Select avianca flight, departing Mon, 15 Feb from Guayaquil to Santiago, returning Fri, 19 Feb, priced at AU$681 found 5 hours ago
LATAM Airlines Group
Tue, 4 Aug - Tue, 18 Aug
GYE
Guayaquil
SCL
Santiago
AU$698 Return, found 2 days ago
AU$698
Return
found 2 days ago
Select LATAM Airlines Group flight, departing Tue, 4 Aug from Guayaquil to Santiago, returning Tue, 18 Aug, priced at AU$698 found 2 days ago
LATAM Airlines Group
Mon, 15 Feb - Fri, 19 Feb
GYE
Guayaquil
SCL
Santiago
AU$699 Return, found 5 hours ago
AU$699
Return
found 5 hours ago
Select LATAM Airlines Group flight, departing Mon, 15 Feb from Guayaquil to Santiago, returning Fri, 19 Feb, priced at AU$699 found 5 hours ago
Copa
Mon, 15 Feb - Fri, 19 Feb
GYE
Guayaquil
SCL
Santiago
AU$788 Return, found 5 hours ago
AU$788
Return
found 5 hours ago
Select Copa flight, departing Mon, 15 Feb from Guayaquil to Santiago, returning Fri, 19 Feb, priced at AU$788 found 5 hours ago

Find the cheapest month to fly from Guayaquil (GYE) to Santiago (SCL)

May is typically the cheapest month to fly

From AU$491 - AU$720 per traveller.

Frequently asked questions

How much does a flight from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez) cost?
You can find one-way and return flights from GYE to SCL with Expedia. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see our cheapest fares first, and use the Price Tracking tool to receive alerts when GYE to SCL ticket fares go up or down.
What is the cheapest month to fly from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez)?
The cheapest months to fly from GYE to SCL are typically during off-peak season when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you are able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez)?
Only one airline offers direct flights from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez).LATAM Airlines Group operates 7 direct flights from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez) every week.
How do I find cheap flights from Guayaquil (GYE) to Santiago (SCL)?
To find a cheap flight from Guayaquil (GYE) to Santiago (SCL), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best airline to fly with from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez)?
The best airline to fly with from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez) will differ from traveler to traveler. If you like to fly early, LATAM Airlines Group offers early morning flights. If price is the most important factor, LATAM Airlines Group typically offers the lowest fares. LATAM Airlines Group offers the most daily flights from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez), which is great if flexibility is what you value most. The best carrier for this journey could also be the one you have a loyalty membership with, as flying with that airline or another airline within the same alliance could help you collect points or enjoy lounge access.
What is the best time to fly from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
How many flights per day from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez)?
There is 1 nonstop flight per day from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez). For even more choices, look at flights that include layovers, as there are around 25 connecting flights per day. Some common connection points include Mariscal Sucre Intl., Tocumen Intl., and Jorge Chavez Intl.
What is the earliest flight from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez)?
The earliest flight from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez) typically departs around 3:30 AM local time. This flight is operated by Avianca and is available year-round. An early departure like this can help you make the most of your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez)?
You'll find the most flights from Guayaquil (GYE) to Santiago (SCL) on Thursdays, with around 16 flights available. This gives you a good selection of options for your travel plans. Major airlines on this route include Avianca, Copa, and LATAM Airlines Group. Flight schedules are quite consistent throughout the week, so you'll have plenty of choices no matter which day you choose to fly.
What are the most popular departure times for flights from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez)?
The most popular departure times for flights from Guayaquil (GYE) to Santiago (SCL) are in the afternoon, from 3pm to 6pm. Many major carriers, including LATAM Airlines Group and Avianca, offer flights during this window. Many travelers prefer this because it allows for a productive morning before heading to the airport, and you'll arrive in Santiago in the evening.
How long does it take to fly from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez)?
A non-stop flight from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez) typically takes around 4 hours 45 minutes. This route covers a distance of approximately 3,602 kilometres. If you opt for a flight with one stop, your travel time will be significantly longer, usually around 18 hours 48 minutes. Flights with two or more stops generally take about 12 hours 30 minutes. Keep in mind that actual flight times can vary due to factors like wind patterns and air traffic, so it's always a good idea to allow for some extra time when planning your journey.
Can you fly business or first class from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez)?
Yes, you can fly business class between GYE and SCL. You can fly business class with Copa and Avianca.
How do I earn miles on a Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez) flight with Expedia?
It's easy to earn miles on a Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Santiago (SCL) from Guayaquil (GYE)?
If you're planning to travel to Santiago from Jose Joaquin de Olmedo Intl. (GYE), you can fly directly into Arturo Merino Benitez (SCL). Some flights may connect through major hubs like Mariscal Sucre Intl. (UIO), Jorge Chavez Intl. (LIM) before reaching Santiago. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez) at the last minute?
Typically, booking a last minute flight from Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez) flight and hotel package?
Securing a Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) to Santiago (SCL-Arturo Merino Benitez) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Guayaquil (GYE) to Santiago (SCL)?
If you booked your Guayaquil (GYE) to Santiago (SCL) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Jose Joaquin de Olmedo Intl.
Destination airport
Arturo Merino Benitez
Return price
AU$631
Distance
3580 km
Average flight time
3 hours 51 mins

Book with confidence

Your quick guide to flights from Guayaquil to Santiago

Pick up great flights from Guayaquil to Santiago

With Expedia, you have your pick of flights a day with 20 airlines covering flights from Guayaquil to Santiago. Whether you’re on a business trip, a family holiday or a luxury break, just enter your travel dates, hit search then check out your choice of flights. Select from return, one way or multi-city flights, and use the advance search tool if you want a direct or refundable flight. You can narrow your search to show you just your preferred cabin class and airline, too. It’s all easy. You can book direct flights from Guayaquil to Santiago that take around hours.

Find cheap flights from Guayaquil to Santiago

From the great flight deals with prices currently ranging from AU$632 to AU$788, you can choose to see the cheapest flights first. Generally, you can book the cheapest flights from Guayaquil to Santiago around 4 to 6 weeks in advance. If your travel dates are flexible, try to avoid weekends and peak seasons – when you are more likely to grab the lowest prices. Even last minute, there are some impressive deals. The cheapest time to fly to Santiago is normally in February.

Reasons to book your flight from Guayaquil to Santiago with Expedia

Expedia makes it easy to find, book, and travel, with everything you need all in one place. When you enter your travel details, find fantastic deals just for you on flight tickets from Guayaquil to Santiago across all the main airline carriers, so you can save time, dollars, and hassle finding the perfect flight. If you think your plans could change, choose refundable flights so any changes won’t cost you more. Book your flight to Santiago right now and, if you join Expedia Rewards, you earn points this time and every time you travel with Expedia.

Your quick guide to flights from Guayaquil to Santiago

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*Available to Expedia members.