Cheap flights from Medellin to Panama City

View AU$316 flight on Mon, 6 Oct. 2025Opens in a new window

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Cheap Flights from Medellin (MDE) to Panama City (PTY)

Prices were available within the past 7 days for one-way flights and round trip tickets for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Mon, 22 Sep. - Mon, 29 Sep.
MDE
Medellin
PTY
Panama City
AU$487 Return, found 6 days ago
AU$487
Return
found 6 days ago
Select Copa flight, departing Mon, 22 Sep. from Medellin to Panama City, returning Mon, 29 Sep., priced at AU$487 found 6 days ago
Copa
Mon, 22 Sep. - Mon, 29 Sep.
MDE
Medellin
PTY
Panama City
AU$520 Return, found 6 days ago
AU$520
Return
found 6 days ago
Select Copa flight, departing Mon, 22 Sep. from Medellin to Panama City, returning Mon, 29 Sep., priced at AU$520 found 6 days ago
Copa
Mon, 22 Sep. - Mon, 29 Sep.
MDE
Medellin
PTY
Panama City
AU$552 Return, found 6 days ago
AU$552
Return
found 6 days ago
Select Copa flight, departing Mon, 22 Sep. from Medellin to Panama City, returning Mon, 29 Sep., priced at AU$552 found 6 days ago
Copa
Mon, 6 Oct. - Fri, 10 Oct.
MDE
Medellin
PTY
Panama City
AU$556 Return, found 4 days ago
AU$556
Return
found 4 days ago
Select Copa flight, departing Mon, 6 Oct. from Medellin to Panama City, returning Fri, 10 Oct., priced at AU$556 found 4 days ago
Copa
Mon, 22 Sep. - Mon, 29 Sep.
MDE
Medellin
PTY
Panama City
AU$585 Return, found 6 days ago
AU$585
Return
found 6 days ago
Select Copa flight, departing Mon, 22 Sep. from Medellin to Panama City, returning Mon, 29 Sep., priced at AU$585 found 6 days ago
avianca
Mon, 22 Sep. - Mon, 29 Sep.
MDE
Medellin
PTY
Panama City
AU$695 Return, found 6 days ago
AU$695
Return
found 6 days ago
Select avianca flight, departing Mon, 22 Sep. from Medellin to Panama City, returning Mon, 29 Sep., priced at AU$695 found 6 days ago

Find the cheapest month to fly from Medellín (MDE) to Panama City (PTY)

March is typically the cheapest month to fly

From AU$315 - AU$635 per traveller.

Graph displaying average flight prices per month

*Available to Expedia members.