Cheap flights from Houston to South Carolina Midlands

View AU$167 flight on Mon, 1 Sep. 2025Opens in a new window

Popular airlines from Houston to South Carolina Midlands

  • Jetstar

    Jetstar

  • Qantas Airways

    Qantas Airways

  • Virgin Australia

    Virgin Australia

  • Scoot

    Scoot

  • American Airlines

    American Airlines

  • Emirates

    Emirates

  • United

    United

  • Plan, book, fly with confidence

  • trending down icon

    Be in the know

    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon

    Book smarter

    Save up to 35% on select hotels after you book a flight*
  • payments icon

    Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Cheap Flights from Houston (HOU) to South Carolina Midlands (CAE)

Prices were available within the past 7 days for one-way flights and round trip tickets for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Thu, 4 Sep. - Mon, 8 Sep.
IAH
Houston
CLT
Charlotte
AU$242 Return, found 1 day ago
AU$242
Return
found 1 day ago
Select American Airlines flight, departing Thu, 4 Sep. from Houston to Charlotte, returning Mon, 8 Sep., priced at AU$242 found 1 day ago
American Airlines
Sun, 21 Sep. - Tue, 30 Sep.
IAH
Houston
CLT
Charlotte
AU$269 Return, found 1 day ago
AU$269
Return
found 1 day ago
Select American Airlines flight, departing Sun, 21 Sep. from Houston to Charlotte, returning Tue, 30 Sep., priced at AU$269 found 1 day ago
American Airlines
Sun, 21 Sep. - Tue, 30 Sep.
IAH
Houston
CLT
Charlotte
AU$296 Return, found 1 day ago
AU$296
Return
found 1 day ago
Select American Airlines flight, departing Sun, 21 Sep. from Houston to Charlotte, returning Tue, 30 Sep., priced at AU$296 found 1 day ago
American Airlines
Mon, 1 Sep. - Mon, 8 Sep.
IAH
Houston
CLT
Charlotte
AU$298 Return, found 6 days ago
AU$298
Return
found 6 days ago
Select American Airlines flight, departing Mon, 1 Sep. from Houston to Charlotte, returning Mon, 8 Sep., priced at AU$298 found 6 days ago
Delta
Sun, 21 Sep. - Tue, 30 Sep.
IAH
Houston
CLT
Charlotte
AU$333 Return, found 1 day ago
AU$333
Return
found 1 day ago
Select Delta flight, departing Sun, 21 Sep. from Houston to Charlotte, returning Tue, 30 Sep., priced at AU$333 found 1 day ago
United
Thu, 4 Sep. - Mon, 8 Sep.
IAH
Houston
CLT
Charlotte
AU$350 Return, found 1 day ago
AU$350
Return
found 1 day ago
Select United flight, departing Thu, 4 Sep. from Houston to Charlotte, returning Mon, 8 Sep., priced at AU$350 found 1 day ago

Find the cheapest month to fly from Houston (HOU) to Columbia (CAE)

June is typically the cheapest month to fly

From AU$281 - AU$615 per traveller.

Graph displaying average flight prices per month

*Available to Expedia members.