Search Southwest Houston hotels

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Southwest Houston hotels

Palace Inn Post Oak

Palace Inn Post Oak
2.5 star property
Houston
9.0 out of 10, Wonderful, (26 reviews)
"Great and clean.. perfect location "
United States
Tiffany
The price is AU$123
includes taxes & fees
9 June - 10 June
Palace Inn Post Oak

Scottish Inns & Suites at NRG Park

Scottish Inns & Suites at NRG Park
2.5 star property
Astrodome
8.6 out of 10, Excellent, (450 reviews)
"Enjoyed our stay!"
United States
Pamela
The price is AU$149
includes taxes & fees
9 June - 10 June
Scottish Inns & Suites at NRG Park

Hyatt Place Houston Medical Center

Hyatt Place Houston Medical Center
3.0 star property
Texas Medical Center
9.2 out of 10, Wonderful, (2,532 reviews)
"Had a great stay!"
United States
Kelly
The price is AU$211
includes taxes & fees
5 July - 6 July
Hyatt Place Houston Medical Center

Home2 Suites by Hilton Houston Medical Center, TX

Home2 Suites by Hilton Houston Medical Center, TX
3.0 star property
Texas Medical Center
9.4 out of 10, Exceptional, (673 reviews)
"Friendly staff, clean rooms, and great buffet breakfast."
United States
Sebastian
The price is AU$224
includes taxes & fees
5 July - 6 July
Home2 Suites by Hilton Houston Medical Center, TX

Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton
4.0 star property
Texas Medical Center
9.0 out of 10, Wonderful, (3,876 reviews)
"Amazing stay!"
United States
Chasity
The price is AU$284
includes taxes & fees
9 July - 10 July
Blossom Hotel Houston, Curio Collection by Hilton

Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center
4.5 star property
Texas Medical Center
8.4 out of 10, Very good, (1,958 reviews)
"A beautiful hotel with professional staff, 5-star service, a wonderful breakfast, and incredible, flawless cleanliness."
United States
Giuseppe
The price is AU$216
includes taxes & fees
5 July - 6 July
Hilton Houston Plaza/Medical Center

Relux at Westchase

Relux at Westchase
2.5 star property
Chinatown
9.2 out of 10, Wonderful, (27 reviews)
"Clean rooms great servi"
United States
Garry S
The price is AU$107
includes taxes & fees
9 June - 10 June
Relux at Westchase

Hilton Garden Inn Houston Medical Center, TX

Hilton Garden Inn Houston Medical Center, TX
3.0 star property
Texas Medical Center
9.2 out of 10, Wonderful, (1,014 reviews)
"NICE PLACE TO STAY"
United States
Tonja
The price is AU$230
includes taxes & fees
5 July - 6 July
Hilton Garden Inn Houston Medical Center, TX

Drury Inn & Suites Houston Near the Galleria

Drury Inn & Suites Houston Near the Galleria
3.0 star property
The Galleria
9.4 out of 10, Exceptional, (1,432 reviews)
"It was a great hotel clean good food and lively staff"
United States
Kesley
The price is AU$176
includes taxes & fees
7 July - 8 July
Drury Inn & Suites Houston Near the Galleria

Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG

Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG
2.5 star property
Braeswood Place
9.4 out of 10, Exceptional, (1,010 reviews)
"Nice place to stay. Clean, convenient and friendly staff"
United States
Lini Jay
The price is AU$209
includes taxes & fees
7 July - 8 July
Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG

Crystal Inn Missouri City

Crystal Inn Missouri City
2.0 star property
Houston
8.4 out of 10, Very good, (44 reviews)
"It is a new building and I really enjoyed my stay here and the bed was super soft "
United States
Haniel
The price is AU$141
includes taxes & fees
9 June - 10 June
Crystal Inn Missouri City

Hampton Inn & Suites Houston Medical Center NRG Park

Hampton Inn & Suites Houston Medical Center NRG Park
2.5 star property
Texas Medical Center
8.4 out of 10, Very good, (1,016 reviews)
"Room and staff were great!"
United States
Javier
The price is AU$166
includes taxes & fees
5 July - 6 July
Hampton Inn & Suites Houston Medical Center NRG Park

Crystal Suites

Crystal Suites
2.0 star property
Central Southwest
6.4 out of 10, (120 reviews)
"Perfect for what we needed it for Enjoy our stay every time we go "
United States
Theresa
The price is AU$149
includes taxes & fees
9 June - 10 June
Crystal Suites

Hyatt Place Houston/Galleria

Hyatt Place Houston/Galleria
3.0 star property
Greater Uptown
8.8 out of 10, Excellent, (1,484 reviews)
"Everything was super clean and nice, I loved my stay there, the manager was also amazing!"
United States
Shirley
The price is AU$196
includes taxes & fees
11 June - 12 June
Hyatt Place Houston/Galleria

Palace Inn Blue US 59 & Gessner

Palace Inn Blue US 59 & Gessner
2.5 star property
Sharpstown
9.2 out of 10, Wonderful, (131 reviews)
"Was very clean"
United States
Maria
The price is AU$127
includes taxes & fees
24 June - 25 June
Palace Inn Blue US 59 & Gessner

Wingate Houston near NRG Park/Medical Center

Wingate Houston near NRG Park/Medical Center
3.0 star property
South Main
6.6 out of 10, (1,006 reviews)
"Good parking"
United States
joseph
The price is AU$149
includes taxes & fees
9 June - 10 June
Wingate Houston near NRG Park/Medical Center

The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District
4.0 star property
Texas Medical Center
9.2 out of 10, Wonderful, (1,160 reviews)
"Clean room,restaurant exceptional,excellent staff."
United States
Craig
The price is AU$332
includes taxes & fees
5 July - 6 July
The Westin Houston Medical Center/Museum District

Hotel Ylem

Hotel Ylem
3.5 star property
Braeswood Place
8.4 out of 10, Very good, (1,471 reviews)
"Staff was very friendly and room was clean. Would definitely stay here again."
United States
Albert
The price is AU$126
includes taxes & fees
7 July - 8 July
Hotel Ylem

Comfort Suites Houston near Medical Center- NRG Stadium

Comfort Suites Houston near Medical Center- NRG Stadium
2.5 star property
South Main
8.6 out of 10, Excellent, (1,006 reviews)
"Clean & comfortable, super nice staff, good breakfast options, convenient to MDA."
United States
Cleota
The price is AU$155
includes taxes & fees
11 June - 12 June
Comfort Suites Houston near Medical Center- NRG Stadium

Hyatt House Houston Medical Center

Hyatt House Houston Medical Center
3.0 star property
Texas Medical Center
9.2 out of 10, Wonderful, (1,244 reviews)
"Clean rooms and excellent staff"
United States
Ray
The price is AU$211
includes taxes & fees
5 July - 6 July
Hyatt House Houston Medical Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Holiday Rentals in Southwest Houston

Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Southwest Houston attractions

Learn more about Southwest Houston

Sports teams, live music and top sights like NRG Stadium—discover it all in Southwest Houston.

Photo by George Zimzores
Open Photo by George Zimzores

Top Southwest Houston Hotel Reviews

More cheap accommodation in Southwest Houston

Explore a world of travel with Expedia