South Main Hotels, Houston

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6554 Cheap Hotels in South Main - Specials, Reviews, & Last Minute Deals

Wyndham Houston near NRG Park/Medical Center
3.5 star property
7.2 out of 10, Good, (1180)
"Everyone was very pleasant, I will be returning."
Amy
The price is AU$178
includes taxes & fees
19 Oct - 20 Oct
Wyndham Houston near NRG Park/Medical Center
Quality Inn & Suites NRG Park - Medical Center
2.5 star property
6.6 out of 10, (1008)
"The rooms were clean, the beds were soft, the staff was friendly. The breakfast wasnt bad either. It was literally the best bang for our buck. "
Carolina
The price is AU$106
includes taxes & fees
17 Nov - 18 Nov
Quality Inn & Suites NRG Park - Medical Center
Wingate Houston near NRG Park/Medical Center
3.0 star property
6.6 out of 10, (946)
"Walking distance to NRG Stadium "
Corina
The price is AU$142
includes taxes & fees
30 Oct - 31 Oct
Wingate Houston near NRG Park/Medical Center
Candlewood Suites Houston Medical Center by IHG
2.5 star property
7.4 out of 10, Good, (802)
"The staff is great. The area is questionable due to homeless population."
Bryana
The price is AU$134
includes taxes & fees
20 Oct - 21 Oct
Candlewood Suites Houston Medical Center by IHG
Hyatt Regency Houston/Galleria
4.0 star property
9.0 out of 10, Wonderful, (1101)
"Wonderful property!!! Very much enjoyed our stay! "
Matthew
The price is AU$287
includes taxes & fees
2 Nov - 3 Nov
Hyatt Regency Houston/Galleria
Hyatt Place Houston Medical Center
3.0 star property
9.2 out of 10, Wonderful, (2037)
"Great place to stay!"
Jason
The price is AU$252
includes taxes & fees
19 Oct - 20 Oct
Hyatt Place Houston Medical Center
The Lancaster Hotel
4.0 star property
9.8 out of 10, Exceptional, (1011)
"Great place... lots of nice people and nice rooms."
Kenneth
The price is AU$358
includes taxes & fees
25 Oct - 26 Oct
The Lancaster Hotel
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
4.0 star property
8.2 out of 10, Very good, (2704)
"We had a wonderful stay"
Laquinza
The price is AU$222
includes taxes & fees
30 Oct - 31 Oct
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Blossom Hotel Houston, Curio Collection by Hilton
4.0 star property
9.0 out of 10, Wonderful, (3563)
"Great stay "
Alexis
The price is AU$238
includes taxes & fees
16 Nov - 17 Nov
Blossom Hotel Houston, Curio Collection by Hilton
The Whitehall Houston
4.0 star property
8.6 out of 10, Excellent, (1805)
"Great staff nice rooms"
Matthew
The price is AU$258
includes taxes & fees
2 Nov - 3 Nov
The Whitehall Houston
Hyatt House Houston Medical Center
3.0 star property
9.2 out of 10, Wonderful, (1135)
"Great stay"
Kurt
The price is AU$252
includes taxes & fees
19 Oct - 20 Oct
Hyatt House Houston Medical Center
Omni Houston Hotel
4.0 star property
9.0 out of 10, Wonderful, (1017)
"Really enjoyed my stay. "
kenneth
The price is AU$350
includes taxes & fees
9 Nov - 10 Nov
Omni Houston Hotel
Hyatt Regency Houston West
3.5 star property
8.6 out of 10, Excellent, (1201)
"Great stay for work trips."
esther
The price is AU$209
includes taxes & fees
24 Oct - 25 Oct
Hyatt Regency Houston West
La Quinta Inn & Suites by Wyndham Houston Southwest
3.0 star property
7.0 out of 10, Good, (1022)
"Great stay. "
Larissa
The price is AU$117
includes taxes & fees
19 Oct - 20 Oct
La Quinta Inn & Suites by Wyndham Houston Southwest
The Royal Sonesta Houston Galleria
4.0 star property
8.4 out of 10, Very good, (1296)
"Great hotel "
Chad
The price is AU$214
includes taxes & fees
16 Nov - 17 Nov
The Royal Sonesta Houston Galleria
Holiday Inn Express & Suites Houston – Downtown North by IHG
2.5 star property
9.2 out of 10, Wonderful, (594)
"Staff was friendly, room was clean, and quiet area!"
Mary
The price is AU$215
includes taxes & fees
22 Oct - 23 Oct
Holiday Inn Express & Suites Houston – Downtown North by IHG
Club Quarters Hotel Downtown, Houston
4.0 star property
8.4 out of 10, Very good, (3794)
"Lovely place to STAY’nm"
Tiwan
The price is AU$178
includes taxes & fees
17 Nov - 18 Nov
Club Quarters Hotel Downtown, Houston
Haven Inn & Suites Downtown Houston
2.5 star property
9.4 out of 10, Exceptional, (1018)
"Very clean and safe, would stay again"
Krimson
Haven Inn & Suites Downtown Houston
Sonesta ES Suites Houston Galleria
3.0 star property
8.2 out of 10, Very good, (1117)
"Nice stay"
Steven
The price is AU$213
includes taxes & fees
30 Oct - 31 Oct
Sonesta ES Suites Houston Galleria
Home2 Suites by Hilton at the Galleria
3.0 star property
8.8 out of 10, Excellent, (933)
"Easy to get around, clean, spacious rooms, great staff"
Will
The price is AU$191
includes taxes & fees
26 Oct - 27 Oct
Home2 Suites by Hilton at the Galleria
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Our guide on where to stay in South Main

Find the best South Main areas for the activities you enjoy most.

Downtown Houston

Tour the beautiful green spaces, buzzing theater district and professional sports arenas nestled beneath a dramatic cityscape of gleaming skyscrapers.

The Galleria

Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Gerald D. Hines Waterwall Park.

Texas Medical Center

Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.

Montrose

Unique features of Montrose include the theatres and museums. Make a stop by Menil Collection or Houston Center for Photography while you're exploring the area.

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Main Street Square Station.

Top South Main Hotel Reviews

Frequently asked questions

What is South Main like?
You'll be sure to have fun exploring Houston's South Main neighbourhood. Consider a visit to NRG Park as part of your South Main travel plans.
Where is the best hotel for a stay in South Main?
Based on Expedia customer reviews, Comfort Suites Houston near Medical Center- NRG Stadium is the highest ranked property in South Main. This hotel is a short 10-minute walk from NRG Stadium, and it offers free breakfast and free parking. Other top choices in the neighbourhood include Candlewood Suites Houston Medical Center by IHG and Quality Inn & Suites NRG Park - Medical Center.
How many hotels should I expect to find in South Main?
If you're searching for places to stay in Houston, Expedia has something to meet your needs with 64 South Main hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in South Main, will I receive a refund?
Yes, you'll find most hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then filter by "fully refundable" to get the best options available in South Main.
What can I see and do in this Houston neighbourhood?
NRG Park is an attraction you might want to check out while you're in South Main. While you're out sightseeing in Houston, make sure that you visit other sights such as NRG Stadium or NRG Arena.
How can I get around South Main and the greater Houston area?
Ready to get out and explore the city? Fannin South Station is the closest metro station.

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