South Main Hotels, Houston

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Check prices for these dates

Tonight
13 Oct - 14 Oct
Tomorrow
14 Oct - 15 Oct
This weekend
17 Oct - 19 Oct
Next weekend
24 Oct - 26 Oct

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6562 Cheap Hotels in South Main - Specials, Reviews, & Last Minute Deals

Wyndham Houston near NRG Park/Medical Center
Lobby
Wyndham Houston near NRG Park/Medical Center
3.5 star property
7.2 out of 10, Good, (1179)
"Everyone was very pleasant, I will be returning."
The price is AU$179
includes taxes & fees
20 Oct - 21 Oct
Wyndham Houston near NRG Park/Medical Center
Quality Inn & Suites NRG Park - Medical Center
1 bedroom, hypo-allergenic bedding, in-room safe, individually decorated
Quality Inn & Suites NRG Park - Medical Center
2.5 star property
6.6 out of 10, (1005)
"The rooms were clean, the beds were soft, the staff was friendly. The breakfast wasnt bad either. It was literally the best bang for our buck. "
The price is AU$109
includes taxes & fees
13 Nov - 14 Nov
Quality Inn & Suites NRG Park - Medical Center
Wingate Houston near NRG Park/Medical Center
Gazebo
Wingate Houston near NRG Park/Medical Center
3.0 star property
6.6 out of 10, (944)
"Walking distance to NRG Stadium "
The price is AU$143
includes taxes & fees
14 Oct - 15 Oct
Wingate Houston near NRG Park/Medical Center
Candlewood Suites Houston Medical Center by IHG
Exterior
Candlewood Suites Houston Medical Center by IHG
2.5 star property
7.4 out of 10, Good, (802)
"The staff is great. The area is questionable due to homeless population."
The price is AU$134
includes taxes & fees
20 Oct - 21 Oct
Candlewood Suites Houston Medical Center by IHG
Hyatt Place Houston Medical Center
Lobby
Hyatt Place Houston Medical Center
3.0 star property
9.2 out of 10, Wonderful, (2024)
"Great place to stay!"
The price is AU$253
includes taxes & fees
15 Oct - 16 Oct
Hyatt Place Houston Medical Center
Hyatt Regency Houston/Galleria
Outdoor pool, open 6:00 AM to 10:00 PM, pool umbrellas, pool loungers
Hyatt Regency Houston/Galleria
4.0 star property
9.0 out of 10, Wonderful, (1098)
"Wonderful property!!! Very much enjoyed our stay! "
The price is AU$296
includes taxes & fees
2 Nov - 3 Nov
Hyatt Regency Houston/Galleria
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Exterior detail
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
4.0 star property
8.2 out of 10, Very good, (2677)
"Great stay!!!"
The price is AU$222
includes taxes & fees
30 Oct - 31 Oct
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Omni Houston Hotel
Interior
Omni Houston Hotel
4.0 star property
9.0 out of 10, Wonderful, (1013)
"Really enjoyed my stay. "
The price is AU$314
includes taxes & fees
8 Nov - 9 Nov
Omni Houston Hotel
La Quinta Inn & Suites by Wyndham Houston Southwest
Exterior
La Quinta Inn & Suites by Wyndham Houston Southwest
3.0 star property
7.0 out of 10, Good, (1012)
"Great stay. "
The price is AU$121
includes taxes & fees
3 Nov - 4 Nov
La Quinta Inn & Suites by Wyndham Houston Southwest
The Whitehall Houston
City view from property
The Whitehall Houston
4.0 star property
8.6 out of 10, Excellent, (1791)
"Great staff nice rooms"
The price is AU$258
includes taxes & fees
2 Nov - 3 Nov
The Whitehall Houston
Hyatt Regency Houston West
Breakfast, lunch, brunch served; American cuisine, garden views
Hyatt Regency Houston West
3.5 star property
8.6 out of 10, Excellent, (1195)
"Great stay for work trips."
The price is AU$210
includes taxes & fees
24 Oct - 25 Oct
Hyatt Regency Houston West
Holiday Inn Express & Suites Houston – Downtown North by IHG
Exterior
Holiday Inn Express & Suites Houston – Downtown North by IHG
2.5 star property
9.2 out of 10, Wonderful, (592)
"Staff was friendly, room was clean, and quiet area!"
The price is AU$186
includes taxes & fees
19 Oct - 20 Oct
Holiday Inn Express & Suites Houston – Downtown North by IHG
Haven Inn & Suites Downtown Houston
Premium bedding, desk, iron/ironing board, free WiFi
Haven Inn & Suites Downtown Houston
2.5 star property
9.4 out of 10, Exceptional, (1014)
"Was great stay."
Haven Inn & Suites Downtown Houston
The Royal Sonesta Houston Galleria
Exterior
The Royal Sonesta Houston Galleria
4.0 star property
8.4 out of 10, Very good, (1288)
"Great hotel "
The price is AU$233
includes taxes & fees
26 Oct - 27 Oct
The Royal Sonesta Houston Galleria
Club Quarters Hotel Downtown, Houston
Lobby
Club Quarters Hotel Downtown, Houston
4.0 star property
8.4 out of 10, Very good, (3789)
"Lovely place to STAY’nm"
The price is AU$206
includes taxes & fees
23 Oct - 24 Oct
Club Quarters Hotel Downtown, Houston
Sonesta ES Suites Houston Galleria
Lobby
Sonesta ES Suites Houston Galleria
3.0 star property
8.2 out of 10, Very good, (1112)
"Nice stay"
The price is AU$183
includes taxes & fees
17 Oct - 18 Oct
Sonesta ES Suites Houston Galleria
Americas Best Value Inn NRG Park Medical Center
Free self-parking
Americas Best Value Inn NRG Park Medical Center
2.0 star property
7.8 out of 10, Good, (801)
"The room was clean the staff was friendly and check out was easy "
The price is AU$179
includes taxes & fees
15 Oct - 16 Oct
Americas Best Value Inn NRG Park Medical Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Our guide on where to stay in South Main

Find the best South Main areas for the activities you enjoy most.
Discovery Green which includes a high-rise building, a square or plaza and a city

Downtown Houston

Tour the beautiful green spaces, buzzing theater district and professional sports arenas nestled beneath a dramatic cityscape of gleaming skyscrapers.

The Galleria

Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Gerald D. Hines Waterwall Park.

Texas Medical Center

Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.

Menil Collection showing interior views and art

Montrose

Unique features of Montrose include the theatres and museums. Make a stop by Menil Collection or Houston Center for Photography while you're exploring the area.

Houston showing a high-rise building and a city

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Main Street Square Station.

Top South Main Hotel Reviews

Club Quarters Hotel Downtown, Houston

Club Quarters Hotel Downtown, Houston

10/10 Excellent
"The room was very nice..somewhat small excellent staff & amenities. Highly recommend "
Mary 1-night trip
Posted 1 day ago
Club Quarters Hotel Downtown, Houston

Frequently asked questions

What is South Main like?
You'll be sure to have fun exploring Houston's South Main neighbourhood. Consider a visit to NRG Park as part of your South Main travel plans.
Where is the best hotel for a stay in South Main?
Based on Expedia customer reviews, Comfort Suites Houston near Medical Center- NRG Stadium is the highest ranked property in South Main. This hotel is a short 10-minute walk from NRG Stadium, and it offers free breakfast and free parking. Other top choices in the neighbourhood include Candlewood Suites Houston Medical Center by IHG and Quality Inn & Suites NRG Park - Medical Center.
How many hotels should I expect to find in South Main?
If you're searching for places to stay in Houston, Expedia has something to meet your needs with 64 South Main hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in South Main, will I receive a refund?
Yes, you'll find most hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then filter by "fully refundable" to get the best options available in South Main.
What can I see and do in this Houston neighbourhood?
NRG Park is an attraction you might want to check out while you're in South Main. While you're out sightseeing in Houston, make sure that you visit other sights such as NRG Stadium or NRG Arena.
How can I get around South Main and the greater Houston area?
Ready to get out and explore the city? Fannin South Station is the closest metro station.

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