South Main Hotels, Houston
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Our top choices for South Main hotels
Quality Inn & Suites NRG Park - Medical Center
Quality Inn & Suites NRG Park - Medical CenterSouth Main
6.6 out of 10, (1,007 reviews)
"Courteous staff, clean room, quite property"
Javier
The price is AU$111
includes taxes & fees
5 Apr - 6 Apr
Comfort Suites Houston near Medical Center- NRG Stadium
Comfort Suites Houston near Medical Center- NRG StadiumSouth Main
8.6 out of 10, Excellent, (1,006 reviews)
"Clean room, helpful staff and good location to hospital."
George
The price is AU$177
includes taxes & fees
31 Mar - 1 Apr
Candlewood Suites Houston Medical Center by IHG
Candlewood Suites Houston Medical Center by IHGSouth Main
7.4 out of 10, Good, (840 reviews)
"This is a safe, friendly hotel close to MDA Cancer Center"
Myra
The price is AU$129
includes taxes & fees
5 Apr - 6 Apr
Wingate Houston near NRG Park/Medical Center
Wingate Houston near NRG Park/Medical CenterSouth Main
6.6 out of 10, (1,010 reviews)
"Easy access to stadium "
Richard
The price is AU$116
includes taxes & fees
23 Mar - 24 Mar
Wyndham Houston near NRG Park/Medical Center
Wyndham Houston near NRG Park/Medical CenterSouth Main
7.0 out of 10, Good, (1,245 reviews)
"Front desk staff was very professional and kind."
MARINA
The price is AU$149
includes taxes & fees
23 Mar - 24 Mar
Fairfield Inn & Suites Houston Intercontinental Airport
Fairfield Inn & Suites Houston Intercontinental Airport30.6 km from South Main
8.6 out of 10, Excellent, (1,004 reviews)
"Nice stay and friendy staff."
Stephanie
The price is AU$142
includes taxes & fees
2 Apr - 3 Apr
Four Points by Sheraton Houston Intercontinental Airport
Four Points by Sheraton Houston Intercontinental Airport29.9 km from South Main
8.4 out of 10, Very good, (1,018 reviews)
"The staff was friendly and the hotel was clean"
Lisa
The price is AU$139
includes taxes & fees
29 Mar - 30 Mar
Holiday Inn Express & Suites Houston SW - Galleria Area by IHG
Holiday Inn Express & Suites Houston SW - Galleria Area by IHG9.6 km from South Main
8.0 out of 10, Very good, (1,004 reviews)
"Clean room, friendly and responsive staff"
Clara
The price is AU$164
includes taxes & fees
5 Apr - 6 Apr
Sonesta Simply Suites Houston – NASA Clear Lake
Sonesta Simply Suites Houston – NASA Clear Lake31.8 km from South Main
8.2 out of 10, Very good, (1,019 reviews)
"Clean room and very courteous staff."
Fazlur
The price is AU$99
includes taxes & fees
17 Mar - 18 Mar
Hampton Inn Houston-Brookhollow
Hampton Inn Houston-Brookhollow20.4 km from South Main
8.2 out of 10, Very good, (1,005 reviews)
"The staff is awesome! What a great place to stay! "
Cynthia
The price is AU$126
includes taxes & fees
5 Apr - 6 Apr
Hilton Houston North
Hilton Houston North30.5 km from South Main
8.4 out of 10, Very good, (1,010 reviews)
"I had a great stay at this hotel. The room was clean and comfortable."
Victor
The price is AU$192
includes taxes & fees
10 Apr - 11 Apr
Hilton Garden Inn Houston/Bush Intercontinental Airport
Hilton Garden Inn Houston/Bush Intercontinental Airport31.1 km from South Main
8.4 out of 10, Very good, (1,007 reviews)
"Place was amazing and the staff were great!!!"
Marlene
The price is AU$166
includes taxes & fees
22 Mar - 23 Mar
Comfort Suites Houston West at Clay Road
Comfort Suites Houston West at Clay Road22.8 km from South Main
8.4 out of 10, Very good, (1,007 reviews)
"Friendly staff, breakfast excellent perfect location! Will definitely stay here again"
wanda
The price is AU$127
includes taxes & fees
5 Apr - 6 Apr
Home2 Suites by Hilton Houston IAH Airport Beltway 8
Home2 Suites by Hilton Houston IAH Airport Beltway 829.9 km from South Main
8.4 out of 10, Very good, (819 reviews)
"Great room close to airport "
Kelli
The price is AU$135
includes taxes & fees
10 Apr - 11 Apr
Doubletree by Hilton Houston Hobby Airport
Doubletree by Hilton Houston Hobby AirportSoutheast Houston, 14.5 km from South Main
8.8 out of 10, Excellent, (1,017 reviews)
"Excellent stay! The room was very clean and comfortable, and the staff went above and beyond to be friendly and helpful. Check-in was smooth, the amenities were great, and the overall atmosphere made it a relaxing experience. I’d definitely stay here again!"
Wayne
The price is AU$170
includes taxes & fees
3 Apr - 4 Apr
GreenTree Inn Houston IAH Airport
GreenTree Inn Houston IAH Airport31.4 km from South Main
6.8 out of 10, (1,032 reviews)
"Staff was very friendly , room was very clean "
Charlette
The price is AU$89
includes taxes & fees
11 Mar - 12 Mar
Homewood Suites By Hilton Houston IAH Airport Beltway 8
Homewood Suites By Hilton Houston IAH Airport Beltway 829.9 km from South Main
8.4 out of 10, Very good, (955 reviews)
"I really like the hotel
We stayed (5 family members)
The breakfast have a really good taste."
Saul
The price is AU$126
includes taxes & fees
23 Mar - 24 Mar
Holiday Inn Express Houston - Galleria Area by IHG
Holiday Inn Express Houston - Galleria Area by IHGThe Galleria, 8.6 km from South Main
9.4 out of 10, Exceptional, (1,011 reviews)
"Clean room, great staff, great breakfast, comfortable bed. "
Sabine
The price is AU$222
includes taxes & fees
5 Apr - 6 Apr
Palace Inn Blue Edgebrook
Palace Inn Blue Edgebrook16.8 km from South Main
9.4 out of 10, Exceptional, (157 reviews)
"Such a great place to stay! Absolutely amazing!"
Charlette
The price is AU$160
includes taxes & fees
17 Mar - 18 Mar
Crystal Inn - NorthWest - 290
Crystal Inn - NorthWest - 29024.8 km from South Main
9.8 out of 10, Exceptional, (35 reviews)
"The best hotel I’ve been in excellent rooms perfect customer service rooms are phenomenal"
Michael
The price is AU$174
includes taxes & fees
16 Mar - 17 Mar
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Our guide on where to stay in South Main
Find the best South Main areas for the activities you enjoy most.
Downtown Houston
Tour the beautiful green spaces, buzzing theater district and professional sports arenas nestled beneath a dramatic cityscape of gleaming skyscrapers.
The Galleria
Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Williams Tower.
Texas Medical Center
Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.
Photo by George Zimzores
Open Photo by George Zimzores
Houston Central Business District
If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Downtown Transit Center Station.
Montrose
Unique features of Montrose include the theatres and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.
Top South Main Hotel Reviews
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
10/10 Excellent
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