South Main Holidays

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Your South Main Holiday

Take the stress out of planning your next escape by booking a South Main holiday package. Take in the sights and sounds of this wonderful neighbourhood and enjoy what it has to offer. Hoping to sightsee during your trip to South Main? Don't miss nearby attractions such as NRG Stadium, NRG Park and Rice Stadium. Expedia will help you turn your ideal South Main holiday into reality, whatever your budget or travel plans.

Our guide on where to stay in South Main

Find the best South Main areas and neighborhoods for the activities you enjoy most. Learn more about South Main
Downtown Houston

Downtown Houston

3 out of top 10 points of interest in this area
4/5(38 area reviews)

Tour the beautiful green spaces, buzzing theater district and professional sports arenas nestled beneath a dramatic cityscape of gleaming skyscrapers.

Find hotels in Downtown Houston

Our pick of the best South Main Hotel Deals

Wyndham Houston near NRG Park/Medical Center

Wyndham Houston near NRG Park/Medical Center

3.5 out of 5
8686 Kirby Drive Houston TX
The price is AU$155 per night from 26 Apr to 27 Apr
AU$155
26 Apr - 27 Apr
includes taxes & fees
7/10 Good! (1,273 reviews)
The staff was not nice !! The place is very dated !!! And had a smell to it !!!!!

Reviewed on 1 Apr 2026

Wyndham Houston near NRG Park/Medical Center
DoubleTree by Hilton Hotel & Suites Houston by the Galleria

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

4 out of 5
5353 Westheimer Rd Houston TX
Fully refundableReserve now, pay when you stay
The price is AU$254 per night from 5 Apr to 6 Apr
AU$254
5 Apr - 6 Apr
includes taxes & fees
8.4/10 Very Good! (3,675 reviews)
The staff was very helpful and nice however, the bathtub had a slow drain and the bathroom floor had a dried up contact lens on the floor. There was only one trash can in the room and you could visibly see stains on the couch, and carpet in the room… even an oil spot on the comforter. I still gave ...

Reviewed on 2 Apr 2026

DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District

4.5 out of 5
5701 Main Street Houston TX
Fully refundableReserve now, pay when you stay
The price is AU$470 per night from 30 Apr to 1 May
AU$470
30 Apr - 1 May
includes taxes & fees
9/10 Wonderful! (1,000 reviews)
Yes

Reviewed on 30 Mar 2026

Hotel Zaza Houston Museum District
See all 6,549 properties in South Main
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
All Inclusive Holidays
Cheap Holidays
Cheap Holidays
Cheap Holidays
beach holidays
Beach Holidays
Beach Holidays

Frequently asked questions

How much does a South Main holiday package cost?
Get set to book, because a getaway to South Main starts from an enticing . When you combine your flights, hotels and more into a travel package, you'll walk away with the best bargains.
How do I get a cheap travel package to South Main?
You'll save tons of cash if you bundle your car rentals, hotels and flights into a South Main holiday package. Sometimes cheap means fewer options. But that's not the case with Expedia. We offer over 550 airlines and 1 000 000 hotels across the globe, which means you'll always have plenty of variety to choose from. Like to save even more? Add some interesting activities to your package deal to unlock even bigger bargains! After all, travel is about more than just getting to your destination.
Where should I stay in South Main?
Book a hotel within walking distance of Houston Zoo, one of this neighbourhood's most popular attractions. It's the perfect spot if you're an eager sightseer.
What are the top hotels in South Main?
Get your trip off to a fantastic start by booking a stay at Travellers Dream 1bd 1 Bath Getaway. It's one of most popular hotels in South Main. Another welcoming option is Luxury King And Queen 1bedroom Suite | Nrg Stadium | Medical Ctr | Galleria | Downtown.
How far in advance should I book my South Main holiday?
It all depends on the air carrier, but you can usually browse through international airfares on Expedia nearly a year in advance. While it's a good idea to book ahead of time, lucky customers occasionally find a cheaper seat just weeks before the date of departure.
What does an Expedia South Main travel package include?
Flights, car rentals and hotels — we bring you all the best deals. All you have to do is figure out your favourite combination. Once you've made your booking, you can add on the exciting stuff like sightseeing activities. Our travel packages make it easy to customize an unforgettable South Main holiday.
What should I know before booking a South Main travel package?
You can save big by bundling your hotels, airfares and rental cars. Once you've made your booking, you can add on things like sightseeing tours or experiences. Your next unforgettable adventure is only a couple of clicks away.
Can I choose my airline with a South Main Expedia holiday package?
You certainly can. Expedia has access to more than 550 airline partners around the world, so fly with the carrier that best suits your needs.
If I'm not able to travel, can I cancel my South Main holiday package?
It's hard to predict what the future holds, so it's comforting to know that you can change or cancel your South Main holiday package. If you made your booking in the last 24 hours, you may be entitled to a refund. If it's an older booking, your airline, hotel or car rental company may charge a fee. Visit our Customer Service Portal to learn more.

Discover the most popular places to visit in South Main

The George R. Brown Convention Center

George R. Brown Convention Center

4.5/5(6 reviews)

During your trip, find out what's happening in George R. Brown Convention Center, a top convention centre in Houston. Experience the entertainment choices and acclaimed art galleries in this vibrant area.

George R. Brown Convention Center
NRG Stadium

NRG Stadium

Catch an event at NRG Stadium during your trip to Houston. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

NRG Stadium
Houston, Texas Reflections

MD Anderson Cancer Center

If MD Anderson Cancer Center is what brings you to town, hopefully you'll have a chance to explore more of Houston.

MD Anderson Cancer Center

Activities

Space Center Houston Admission Ticket

Space Center Houston Admission Ticket

AU$46
per adult
92% of travellers recommend
Space Center Houston Admission Ticket
Astroville Tunnel Tour of Downtown Houston

Astroville Tunnel Tour of Downtown Houston (Air-Conditioned)

AU$36
per adult
100% of travellers recommend
Astroville Tunnel Tour of Downtown Houston (Air-Conditioned)
Houston: Houston Botanic Garden Entry Ticket

Houston: Houston Botanic Garden Entry Ticket

AU$17
per adult
80% of travellers recommend
Houston: Houston Botanic Garden Entry Ticket
See all activities in Houston
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.