Sikeston Hotel & Accommodation Deals 2026 from AU$89 - Compare prices by date

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Go beyond your typical stay in Sikeston

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Our top choices for Sikeston hotels

An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.

An outdoor seating area with sofas and planters, surrounded by a building with large windows and a brick wall.

A hotel room with a patterned sofa, a yellow ottoman, a desk with a TV, and a framed picture on the wall.

A spacious lobby with a polished floor, seating areas, and modern lighting fixtures.

1. Drury Inn & Suites Sikeston, MO

Sikeston

Scott Andrew

AU$150

includes taxes & fees

13 Sept - 14 Sept

An outdoor seating area with a circular fire pit surrounded by chairs, a covered patio, and a building with large windows in the background.

A modern indoor swimming pool with clear glass walls, a tiled deck, and multiple lounge chairs.

A modern lobby with a green sofa, two armchairs, a wooden coffee table, and a patterned rug.

An outdoor bar area with a modern design, featuring a counter, seating, and a view of the interior.

2. Fairfield Inn & Suites by Marriott Sikeston

Sikeston

Allen

AU$159

includes taxes & fees

13 Sept - 14 Sept

A hotel room with two beds, a desk with a chair, a TV, and a window with curtains.

A buffet with various food items, including omelets and baked goods, served in metal containers.

A kitchenette with a coffee machine, a kettle, and storage shelves.

A reception area with a reception desk, a large wall-mounted sign, and a potted plant.

3. Holiday Inn Express & Suites Sikeston Southwest by IHG

Sikeston

Melissa

AU$176

includes taxes & fees

27 Sept - 28 Sept

A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.

A conference room with a large rectangular table, six chairs with patterned upholstery, two modern ceiling lights, a bowl of fruit on the table, and large windows with curtains.

An indoor swimming pool with lounge chairs, a lifeguard stand, and large windows offering a view of the outside.

A hotel lobby with a bar area, seating arrangements, and a large window providing natural light.

4. Hampton Inn Sikeston

Sikeston

Jeffrey

AU$160

includes taxes & fees

13 Sept - 14 Sept

A hotel lobby with a central bar area, multiple dining tables and chairs, large windows, and a patterned carpet.

A reception area with a wooden reception desk, a large painting on the wall, and a potted plant.

A hotel with a covered entrance, a sign indicating a restaurant, and a well-lit parking area.

5. Best Western Plus Sikeston I-55

Sikeston

Crystal

AU$138

includes taxes & fees

27 Sept - 28 Sept

A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.

A Drury Plaza Hotel with a modern design, featuring a prominent entrance, multiple floors, and a clear sky.

A spacious corridor with a high ceiling, recessed lighting, and a series of posters on the walls.

A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.

6. Drury Plaza Hotel Cape Girardeau Conference Center

Cape Girardeau

Sandra

AU$157

includes taxes & fees

13 Sept - 14 Sept

A hotel room with a large bed, a desk with a computer, a chair, a window with a view, and a wall-mounted TV.

A living room with a sofa, two chairs, a coffee table, a television, and a window with blinds.

A reception area with a sign for 'Travel Inn and Suites'.

A modern kitchen with stainless steel appliances, wooden cabinets, and a bright yellow accent wall.

7. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Sikeston

Sharika West

AU$89

includes taxes & fees

13 Sept - 14 Sept

A modern hotel room with a large bed, a smaller bed, a desk, and a chair. There is a window with curtains and a painting on the wall.

A Days Inn hotel with a brick facade, large windows, and a sign above the entrance.

A spacious lobby with a central atrium, a piano, and a reception desk.

8. Days Inn and Suites by Wyndham Sikeston

Sikeston

Lori

AU$105

includes taxes & fees

10 Sept - 11 Sept

A modern hotel room with a large window, a gray sofa, a small round table, a white chair, and a bed.

An outdoor bar area with a modern design, featuring a counter, bar stools, and a seating area with chairs.

9. TownePlace Suites by Marriott Sikeston

Sikeston

Lauren

AU$179

includes taxes & fees

13 Sept - 14 Sept

A hotel room with a bed, a desk with a chair, a TV, two bedside lamps, and a large window.

A hotel room with a flat-screen TV, a microwave, a coffee maker, a dining table, and two sofas.

A hotel room with two beds, a sofa, a coffee table, and artwork on the walls.

A motel with a covered entrance, multiple rooms, and a parking lot.

10. Super 8 by Wyndham Sikeston/Miner Area

Sikeston

Kevin

AU$90

includes taxes & fees

13 Sept - 14 Sept

A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.

A reception area with a wooden reception desk, two blue armchairs with orange cushions, a patterned side table, and a wall-mounted lamp.

A Dear Tree Inn building with a covered entrance and a clear sky at dusk.

A hotel room with two beds, a window with curtains, an air conditioning unit, and a lamp on a nightstand.

11. Pear Tree Inn Cape Girardeau West

Cape Girardeau

Raidas

AU$113

includes taxes & fees

13 Sept - 14 Sept

A Comfort Inn & Suites hotel with a clear entrance, a covered parking area, and a sign indicating a 12' clearance.

A living room with two sofas, a coffee table, a TV, and a cabinet.

A hotel lobby with a reception desk, seating area, and large windows offering a view of the outdoors.

A hot tub area with a tiled floor, a wooden deck surrounding the tub, and a view of the sky through large windows.

12. Comfort Inn & Suites Sikeston I-55

Sikeston

Lakeysha

AU$138

includes taxes & fees

27 Sept - 28 Sept

A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.

A spacious hotel lobby with a high ceiling, a central seating area with sofas and chairs, a fireplace, and a television mounted on the wall.

A living room with a stone fireplace, a television mounted above it, and a large sofa with cushions.

An indoor swimming pool with a clear view of the pool area, including the pool's edge, a set of stairs leading into the pool, and a few lounge chairs and tables around the pool.

13. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Cape Girardeau

ELAINE

AU$160

includes taxes & fees

10 Sept - 11 Sept

A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.

A breakfast setting with waffles, scrambled eggs, toast, a glass of orange juice, and a white mug on a table with a green placemat.

A bowl of cereal with raisins and milk, a half orange, and a sandwich on a table with a yellow napkin.

A hotel room with a large bed, two bedside tables, a desk with a chair, and two lamps.

14. Drury Inn & Suites Cape Girardeau

Cape Girardeau

Cheryl

AU$141

includes taxes & fees

13 Sept - 14 Sept

A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.

An outdoor patio with tables and chairs, a stone wall, and large windows.

A breakfast bar with a coffee machine, waffle maker, toaster, and various food items.

A reception desk with a large mural of a bridge, wooden reception area, and a potted plant.

15. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Jackson

Andrew

AU$139

includes taxes & fees

9 Sept - 10 Sept

A spacious dining area with high ceilings, large windows, and modern lighting fixtures.

A large indoor swimming pool with clear blue water, surrounded by tiled flooring and blue walls.

A hotel room with a bed, a desk with a television, a chair, a suitcase, and a map on the wall.

A gym with exercise equipment, a treadmill, and a wall-mounted TV.

16. Hampton Inn Cape Girardeau I 55 East

Cape Girardeau

Rebekah

AU$166

includes taxes & fees

13 Sept - 14 Sept

A spacious lobby with marble flooring, elegant seating, and a grand staircase.

A modern hotel lobby with a framed advertisement for breakfast at the new Bistro, a seating area with sofas and a coffee table, and a decorative mirror reflecting the space.

A Courtyard by Marriott hotel with a modern brick facade, large windows, and a covered entrance area.

A lobby with seating areas, a reception desk, and a bar.

17. Courtyard by Marriott Cape Girardeau Downtown

Cape Girardeau

Kristin

AU$197

includes taxes & fees

20 Sept - 21 Sept

A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.

A reception area with a wooden reception desk, a glass door leading to a storage room, and a decorative wall piece.

A modern living room with a sofa, a coffee table, and a dining area with chairs and a table.

An indoor swimming pool with lounge chairs and tables, large windows, and a view of the outside.

18. Fairfield Inn & Suites by Marriott Cape Girardeau

Cape Girardeau

Chevonne

AU$158

includes taxes & fees

13 Sept - 14 Sept

A spacious lobby with a curved staircase, large windows, and a seating area with a rug.

A modern bar area with a herringbone patterned wall, a long counter with bar stools, and a variety of bottles and glasses.

A modern living room with a large sectional sofa, a flat-screen TV, and a view of the sea through large windows.

A hotel room with two beds, a desk, a chair, and a view of the city.

19. The Riverview

Cape Girardeau

Alyssa

AU$163

includes taxes & fees

13 Sept - 14 Sept

A modern retail area with a display of local items and snacks.

A hotel room with two beds, a desk, a chair, a TV, and a window with a view.

A modern indoor seating area with blue sofas and tables, a patterned carpet, and large windows offering a view of the outdoors.

A modern lounge area with seating options including sofas, chairs, and a hanging chair, with large windows providing a view of the outdoors.

20. Tru By Hilton Cape Girardeau

Cape Girardeau

Darlene

AU$141

includes taxes & fees

20 Sept - 21 Sept

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Stay near popular Sikeston attractions

Central Park

7.2/10 (56 reviews)

Central Park offers a peaceful retreat with playgrounds and open spaces for Sikeston families. Bring a blanket for a relaxing picnic or watch children enjoy the recreational facilities.

See properties

Sikeston Depot Museum

7.6/10 (57 reviews)

Housed in a restored 1916 train depot, this museum showcases Sikeston's cotton-growing heritage and local art. Explore regional history through rotating exhibits while admiring the building's National Register status.

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City of Miner Convention Center

This versatile 16,000-square-foot venue in Miner, Missouri hosts conferences, weddings, and community gatherings. Modern meeting rooms and a commercial kitchen make it ideal for various events.

See properties

Sikeston and related destinations

Home to Lambert's Café, the 'Home of Throwed Rolls,' where servers toss fresh bread across the room to hungry diners. Visit the historic Sikeston Depot or catch the annual rodeo where professional cowboys compete in thrilling events each August.

See all hotels in Sikeston

Top Sikeston Hotel Reviews

Recent Reviews in Sikeston

Days Inn and Suites by Wyndham Sikeston

10/10 Excellent

"Clean and friendly staff. Only stayed the one night so didn’t really get a chance to know the staff. But room was clean and price was decent"

Best Western Plus Sikeston I-55

8/10 Good

"Great location, nice, clean and well maintained, Hotel employees were very helpful great customer service,"

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

10/10 Excellent

"Such a great place to stay! Clean friendly delicious breakfast!"

Pear Tree Inn Cape Girardeau West

10/10 Excellent

"Staff very friendly and helpful! Breakfast great and breakfast staff very friendly ! Bed comfortable. Showe gel , shampoo and conditioner on shower wall. Only thing missing was hair dryer. Microwave and fridge in room. Great stay"

Drury Inn & Suites Sikeston, MO

10/10 Excellent

"This was my second time staying at Drury hotel. I will most definitely book another stay."

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

10/10 Excellent

"Comfortable and convenient"

Drury Inn & Suites Cape Girardeau

10/10 Excellent

"Nice place! Breakfast was amazing!"

The Riverview

10/10 Excellent

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Drury Plaza Hotel Cape Girardeau Conference Center

10/10 Excellent

"This was a great place to stay. Everything about it was fantastic. We especially enjoyed the free breakfast and dinner!"