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7 Dec - 8 Dec
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Top hotels and accommodation in Sikeston

Exterior
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1002)
"Our room was very clean and comfortable."
United States
Brian
Travelling for leisure
The price is AU$161
includes taxes & fees
22 Dec - 23 Dec
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Free daily full breakfast
Best Western Plus Sikeston

Best Western Plus Sikeston

2.5 star property
Sikeston
8.4 out of 10, Very good, (1003)
"Completely satisfied with staff, cleanliness of room and surround."
United States
Emila
The price is AU$123
includes taxes & fees
14 Dec - 15 Dec
Best Western Plus Sikeston
Property amenity
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3.0 star property
Jackson
8.8 out of 10, Excellent, (661)
"Staff was friendly comfortable beds. in a nice quiet room"
United States
Nicole
Travelling with family
The price is AU$127
includes taxes & fees
4 Jan - 5 Jan 2026
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Exterior
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

2.5 star property
Sikeston
8.4 out of 10, Very good, (716)
"The room was very clean and the bed was comfortable plus you can not beat the price."
United States
Lori
Travelling with family
The price is AU$90
includes taxes & fees
8 Jan - 9 Jan 2026
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Property amenity
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1002)
"Clean room, great location and friendly staff"
United States
Mark
The price is AU$156
includes taxes & fees
12 Dec - 13 Dec
Drury Inn & Suites Sikeston, MO
Lobby
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1003)
"The rooms are spacious and comfortable."
United States
Kristin
Travelling with family
The price is AU$119
includes taxes & fees
14 Dec - 15 Dec
Pear Tree Inn Cape Girardeau West
Lobby
Quality Inn

Quality Inn

2.5 star property
Cape Girardeau
7.2 out of 10, Good, (680)
"Staff was wonderful and helpful pool was great room was comfortable breakfast needs improvements decent for what they had"
United States
Linda
Travelling for leisure
The price is AU$102
includes taxes & fees
4 Jan - 5 Jan 2026
Quality Inn
Exterior
Hampton Inn Sikeston

Hampton Inn Sikeston

2.5 star property
Sikeston
9.0 out of 10, Wonderful, (440)
"Room was clean and cozy"
United States
Doncheial
Travelling for leisure
The price is AU$162
includes taxes & fees
14 Dec - 15 Dec
Hampton Inn Sikeston
Lobby
Pear Tree Inn Sikeston

Pear Tree Inn Sikeston

2.5 star property
Sikeston
9.4 out of 10, Exceptional, (1002)
"Rooms were nice and clean"
United States
Dale
Travelling for leisure
The price is AU$130
includes taxes & fees
14 Dec - 15 Dec
Pear Tree Inn Sikeston
Front of property – evening/night
Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO

2.0 star property
Charleston
6.6 out of 10, (612)
"Located very close to the expanse of corn fields, quiet, clean rooms"
United States
Yan Robby
Travelling for business
The price is AU$115
includes taxes & fees
9 Dec - 10 Dec
Super 8 by Wyndham Charleston/Sikeston East MO
Exterior
Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG

2.5 star property
Sikeston
8.6 out of 10, Excellent, (443)
"Overall a nice hotel, everything was clean and maintained, staff was helpful."
United States
Sarah
Travelling for leisure
The price is AU$159
includes taxes & fees
21 Dec - 22 Dec
Holiday Inn Express & Suites Sikeston Southwest by IHG
1 bedroom, desk, laptop workspace, blackout curtains
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

2.0 star property
Sikeston
7.2 out of 10, Good, (1002)
"Good mattress on beds great night sleep."
United States
John
Travelling with family
The price is AU$108
includes taxes & fees
14 Dec - 15 Dec
Days Inn and Suites by Wyndham Sikeston
Lobby sitting area
The Riverview

The Riverview

4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (465)
"Nice big rooms and everything is very clean."
United States
Steven
Travelling with small children
The price is AU$149
includes taxes & fees
15 Dec - 16 Dec
The Riverview
Exterior
Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG

2.5 star property
Cape Girardeau
8.2 out of 10, Very good, (878)
"room was clean and spacious"
United States
Lisa
Travelling with family
The price is AU$127
includes taxes & fees
14 Dec - 15 Dec
Candlewood Suites Cape Girardeau by IHG
Lobby
Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO

3.0 star property
Jackson
9.6 out of 10, Exceptional, (1005)
"The room was very clean."
United States
Darla
Travelling for leisure
The price is AU$132
includes taxes & fees
9 Dec - 10 Dec
Drury Inn & Suites Jackson MO
Lobby
Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1004)
"The beds and linens were wonderful"
United States
Bennie
Travelling for business
The price is AU$119
includes taxes & fees
14 Dec - 15 Dec
Pear Tree Inn Cape Girardeau Near the Medical Center
Business centre
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1002)
"Great room, free coffee and soda."
United States
Tara
Travelling with family
The price is AU$153
includes taxes & fees
14 Dec - 15 Dec
Drury Inn & Suites Cape Girardeau
Courtyard
Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East

2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (782)
"The room was spacious, clean and comfortable"
United States
Dean
The price is AU$169
includes taxes & fees
21 Dec - 22 Dec
Hampton Inn Cape Girardeau I 55 East
Lobby
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1001)
"Room was spacious and clean."
United States
Mindy
Travelling solo
The price is AU$153
includes taxes & fees
14 Dec - 15 Dec
Drury Plaza Hotel Cape Girardeau Conference Center
Room, 1 King Bed, Accessible, Non Smoking
Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area

2.0 star property
Sikeston
6.6 out of 10, (561)
"the bed is comfortable and the room seems clean"
United States
Joyce
Travelling with partner
The price is AU$111
includes taxes & fees
14 Dec - 15 Dec
Super 8 by Wyndham Sikeston/Miner Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Great weekend hotel deals in Sikeston, MO

Showing deals for:19 Dec - 21 Dec

Image gallery for The Riverview

Lobby sitting area

The Riverview

4.0 star property
Cape Girardeau
9.4/10Exceptional (465 reviews)
18% off
Price is AU$590
for 2 nights, 1 room
AU$295 per night
includes taxes & fees
The Riverview
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Stay near popular Sikeston attractions

Central Park

3.8/5 (36 reviews)
Explore the great outdoors at Central Park, a lovely green space in Sikeston. While in this relaxing area, you can savour the top-notch restaurants.
See properties

City of Miner Convention Center

Learn about the events happening in City of Miner Convention Center during your trip to Miner. While in this relaxing area, you can savour the top-notch restaurants.
See properties

Sikeston and related destinations

Home to Lambert's Café, the 'Home of Throwed Rolls,' where servers toss fresh bread across the room to hungry diners. Visit the historic Sikeston Depot or catch the annual rodeo where professional cowboys compete in thrilling events each August.

See all hotels in Sikeston
The best restaurant I have EVER been to! Hands down!!!
Photo by Ryan Coleman
Open Photo by Ryan Coleman

Top Sikeston Hotel Reviews

Recent Reviews in Sikeston

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

10/10 Excellent
"Was a great stay. Room walls could have been a bit cleaner but nothing to worry about in the end. Will be staying again. Staff was amazing, bathroom was clean, breakfast was good. "
Chayton 3-night trip
Posted 1 day ago
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

More cheap accommodation in Sikeston

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

220 S Interstate Dr Sikeston MO
The price is AU$108 per night from 14 Dec to 15 Dec
AU$108
14 Dec - 15 Dec
includes taxes & fees
7.2/10 Good! (1,000 reviews)

Frequently asked questions

Where is the best place to stay in Sikeston?
Drury Inn & Suites Sikeston, MO is ranked highly by Expedia customers. This hotel offers free breakfast and an outdoor pool. Other top choices based on reviews include Pear Tree Inn Sikeston and Fairfield Inn & Suites by Marriott Sikeston. See all available top hotels, or vacation rentals in Sikeston.
What are some of the best holiday rentals that Sikeston has to offer?
On the Wine Trail Hot Tub Wi-Fi : This holiday home rental outside of Sikeston is located on a lake, and has a patio, 1 hot tub and a BBQ to put you at ease in your new surroundings. Kitchen amenities include a fridge, a stovetop and a microwave. See all vacation rentals in Sikeston.
If I need to cancel my hotel reservation in Sikeston, will I receive a refund?
Yes, you'll find most room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If your reservation is non-refundable, you might be able to cancel it and be given a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Sikeston.
What's the best budget-friendly hotel in Sikeston?
Based on reviews, Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) is a popular hotel for our travellers who want a more economical choice, and features free breakfast and free Wi-Fi. View all budget hotels in Sikeston.
What's the best family accommodation in Sikeston?
Drury Inn & Suites Sikeston, MO is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Pear Tree Inn Sikeston is another good choice for your family trip. Find more child-friendly accommodations in Sikeston.
What's the best LGBTQ-friendly hotel in Sikeston?
Drury Inn & Suites Sikeston, MO is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi. Pear Tree Inn Sikeston and Hampton Inn Sikeston are two other good choices for your holiday. See all available hotels listed as LGBTQ-friendly in Sikeston.
What's the best dog-friendly hotel in Sikeston?
Drury Inn & Suites Sikeston, MO is a top hotel for people travelling with their pets, and offers an indoor pool and free WiFi for its human guests. Other good choices for you and your pet's trip include Days Inn and Suites by Wyndham Sikeston and Hampton Inn Sikeston. See more pet-friendly hotel accommodations in Sikeston.
What are some hotels with pools in Sikeston?
Best Western Plus Sikeston is a top hotel with a pool, free full breakfast and free self-parking. TownePlace Suites by Marriott Sikeston is another choice with an on-site pool. View all hotels with pools in Sikeston.
What is staying in Sikeston like?
Families will find child-friendly activities in Sikeston, and visitors give high marks for the top-notch restaurants and shopping. This welcoming city also attracts tourists with its riverfront and university setting. In Sikeston, there are 15 hotels and other accommodation options to choose from. Find out more about Sikeston.
What is there to see in Sikeston?
A couple of favourite places to visit are Central Park and Sikeston Depot Museum. You'll also find Front Street Studio & Art Gallery and Stoddard County Civil War Memorial Cemetery in the area. Take a look at what more there is to see and do in Expedia's Sikeston guide.
What's the seasonal weather in Sikeston?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Sikeston is 1536 mm.

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