Sikeston Holiday Rentals

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Our top choices for Sikeston holiday rentals

Little Blue Cottage on Spanish

Little Blue Cottage on Spanish
Cape Girardeau
8.2 out of 10, Very good, (54 reviews)
"Great cute place. "
United States
Jeremy W.
The price is AU$154
includes taxes & fees
27 Apr - 28 Apr
Little Blue Cottage on Spanish

Fresh & Cozy Retreat w/ King Bed · By KeenStays

Fresh & Cozy Retreat w/ King Bed · By KeenStays
Cape Girardeau
The price is AU$237
includes taxes & fees
29 Apr - 30 Apr
Fresh & Cozy Retreat w/ King Bed · By KeenStays

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
Cape Girardeau
8.8 out of 10, Excellent, (40 reviews)
"Will definitely book again! Great location, comfortable stay."
United States
Pynktoria !.
The price is AU$379
includes taxes & fees
4 May - 5 May
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

Charming Secluded Getaway Cabin within minutes of amenities

Charming Secluded Getaway Cabin within minutes of amenities
Cape girardeau
10.0 out of 10, Exceptional, (18 reviews)
"We had a great time at Blair and her family's property. The cabin was very comfortable and as advertised. I would be happy to recommend it to others "
United States
Tammy M.
The price is AU$428
includes taxes & fees
27 Apr - 28 Apr
Charming Secluded Getaway Cabin within minutes of amenities

Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy

Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy
Dexter
7.8 out of 10, Good, (31 reviews)
"Stayed many times. Nice and comfortable "
United States
Susan R.
The price is AU$300
includes taxes & fees
3 May - 4 May
Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy

The Twisted Sassafras Treehouse

The Twisted Sassafras Treehouse
Cape Girardeau
10.0 out of 10, Exceptional, (34 reviews)
"Amazing stay, loved the bed and hot tub. Close to town but also away. "
United States
Maria B.
The price is AU$476
includes taxes & fees
11 May - 12 May
The Twisted Sassafras Treehouse

Relax in the country at Countryside Villas! - Villa A

Relax in the country at Countryside Villas! - Villa A
Jackson
10.0 out of 10, Exceptional, (34 reviews)
"Great place to stay, felt like home away from home. "
United States
Brittany
The price is AU$253
includes taxes & fees
29 Apr - 30 Apr
Relax in the country at Countryside Villas! - Villa A

Serenity South -- Gardens, River-Views, and Refreshing Space

Serenity South -- Gardens, River-Views, and Refreshing Space
Cape Girardeau
10.0 out of 10, Exceptional, (153 reviews)
"It's a great location, great space, great price. And, the muffins are the best!"
United States
Vicki R.
The price is AU$347
includes taxes & fees
27 Apr - 28 Apr
Serenity South -- Gardens, River-Views, and Refreshing Space

Modern 2BR Apt w Electric Fireplace By KeenStays

Modern 2BR Apt w Electric Fireplace By KeenStays
Cape Girardeau
The price is AU$312
includes taxes & fees
3 May - 4 May
Modern 2BR Apt w Electric Fireplace By KeenStays

Villa B offers peace and quiet with beautiful views of the countryside.

Villa B offers peace and quiet with beautiful views of the countryside.
Jackson
10.0 out of 10, Exceptional, (11 reviews)
"It was great. "
United States
Benjamin Q.
The price is AU$254
includes taxes & fees
1 May - 2 May
Villa B offers peace and quiet with beautiful views of the countryside.

Gorgeous 1856 Log Cabin, Completely Renovated

Gorgeous 1856 Log Cabin, Completely Renovated
Jackson
10.0 out of 10, Exceptional, (3 reviews)
"incredible place. I was there for work, but it was a really nice relaxing area to retreat too, and also get some work done in a serene environment. It would be an incredible place for an entire family. And, a good place for friends to get together."
United States
Chandler G.
The price is AU$440
includes taxes & fees
27 Apr - 28 Apr
Gorgeous 1856 Log Cabin, Completely Renovated

Studio Apt | King Bed, Full Kitchen · By KeenStays

Studio Apt | King Bed, Full Kitchen · By KeenStays
Cape Girardeau
Studio Apt | King Bed, Full Kitchen · By KeenStays

The Cottage, Rusted Route Farms

The Cottage, Rusted Route Farms
Jackson
10.0 out of 10, Exceptional, (2 reviews)
"This Cottage was very nice and clean and well maintained. The meat tray that we ordered and the breakfast tray was beyond Fabulous!!! My husband is still talking about it. . .Rick & Renee Christman"
United States
Renee C.
The price is AU$282
includes taxes & fees
28 Apr - 29 Apr
The Cottage, Rusted Route Farms

4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
Cape Girardeau
9.6 out of 10, Exceptional, (9 reviews)
"Nice place, great times"
United States
Jace W.
The price is AU$776
includes taxes & fees
19 May - 20 May
4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

Modern Boho Getaway · 1BR Apartment · By KeenStays

Modern Boho Getaway · 1BR Apartment · By KeenStays
Cape Girardeau
Modern Boho Getaway · 1BR Apartment · By KeenStays

Luxe 2KBR Apt w/ Electric Fireplace · By KeenStays

Luxe 2KBR Apt w/ Electric Fireplace · By KeenStays
Cape Girardeau
The price is AU$291
includes taxes & fees
4 May - 5 May
Luxe 2KBR Apt w/ Electric Fireplace · By KeenStays

Building at Cape Girardeau Regional Airport

Building at Cape Girardeau Regional Airport
Scott City
The price is AU$863
includes taxes & fees
1 May - 2 May
Building at Cape Girardeau Regional Airport

The Atrium - A Boutique Hotel

The Atrium - A Boutique Hotel
2.0 star property
Perryville
8.0 out of 10, Very good, (1 review)
"I like it but there is room for improvement on the little things. For a personal stay and non business it would be a little better. I have stayed twice for business. It’s clean but due to the openness it’s hard to control the temp in the room. My first stay the wifi didn’t work and cell reception is minimal so using phone as a hot spot was less than ideal. I like the kitchenette area and comes with everything you need but no area to use it. If you want to use the electric pan they have you can’t...
United States
Michael
The price is AU$220
includes taxes & fees
3 May - 4 May
The Atrium - A Boutique Hotel

Minutes to Giant City - SIU - Shawnee Winetrail - Shawnee Forest - Wi-Fi

Minutes to Giant City - SIU - Shawnee Winetrail - Shawnee Forest - Wi-Fi
Makanda
9.4 out of 10, Exceptional, (48 reviews)
"Great place to stay and host was wonderful! Definitely would stay again in the future."
United States
Teal B.
The price is AU$256
includes taxes & fees
4 May - 5 May
Minutes to Giant City - SIU - Shawnee Winetrail - Shawnee Forest - Wi-Fi

Rest, Relax and Renew. Our log cabin experience awaits your arrival.

Rest, Relax and Renew. Our log cabin experience awaits your arrival.
Anna
10.0 out of 10, Exceptional, (409 reviews)
"Great location. Cozy cabin. Would stay there again. "
United States
jeffrey s
The price is AU$285
includes taxes & fees
29 Apr - 30 Apr
Rest, Relax and Renew. Our log cabin experience awaits your arrival.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Sikeston Hotel Reviews

Find out more about Sikeston

Everything you need to know about Sikeston holiday rentals

Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the Sikeston holiday rental for you. At Expedia, you can take your pick from private holiday homes, apartments, cottages, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Sikeston holiday rental for you by simply entering your desired dates. Then check your favourite filters to narrow down your search. 

Sikeston holiday rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Sikeston. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depend on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Sikeston holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Sikeston holiday rentals we have selected for you start as low as AU$215 per night. Entering your travel dates in the search wizard might find you even better deals!

How to find incredible deals on Sikeston rentals

At Expedia, we put the best Sikeston holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top Sikeston rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Sikeston holiday.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Sikeston. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. 

Frequently asked questions

Can I find a holiday rental in Sikeston?

Yes, there are holiday rentals close to the most popular sights in Sikeston, or you can select a more secluded option if you're looking for a relaxing stay. Tourists like the array of shops and top-notch restaurants in Sikeston. Make sure you allow time to enjoy the riverfront during your holiday.

What are some of the best holiday rentals that Sikeston has to offer?

* On the Wine Trail * Hot Tub * Wi-Fi *: This holiday home rental outside of Sikeston is located on a lake, and has a patio, 1 hot tub and a BBQ to put you at ease in your new surroundings. Kitchen amenities include a fridge, a stovetop and a microwave.

What’s there to see and do in Sikeston?

Cultural attractions include Sikeston Depot Museum, whereas Central Park is a spot to enjoy nature. In the wider area, you’ll find River Ridge Winery and Front Street Studio & Art Gallery.

What’s a holiday rental in Sikeston like?

Holiday rentals are private properties where you can stay for a few weeks, or just a few days, in Sikeston. Holiday rentals offer amenities such as WiFi and washers and dryers so you'll be comfy for your stay. If you're concerned about a clean environment, a holiday rental can offer a sense of security away from public hotel lifts and bustling concierge desks while still allowing you a great travel experience. You'll also find more space in a holiday rental than in a hotel, which is another reason why a holiday rental is a popular option for family gatherings.