
Sikeston Holidays
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Your Sikeston Holiday
With a reputation for its rich history and rural countryside, Sikeston is an ideal getaway destination. Lock in one of our Sikeston holiday packages and discover all that this lively city has to offer. Fill your schedule with tours of The Book Bug, Sikeston Depot Museum and Central Park, some of the attractions you should see during a trip to Sikeston. Expedia can help you escape your routine. Tailor your holiday to Sikeston to suit your style of travel, whatever that may be!
Sikeston Holiday
Sikeston Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Cape Girardeau Municipal Airport (CGI) |
Population | 16,400 |
Max Temp Winter | 7ºC |
Max Temp Summer | 29ºC |
Top Sights | Sikeston Depot Museum, Central Park and The Book Bug |
Our pick of the best Sikeston Hotel Deals

Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
Fully refundableReserve now, pay when you stay
The price is AU$178 per night from 28 June to 29 June
AU$178
28 June - 29 June
includes taxes & fees
9.6/10 Exceptional! (1,005 reviews)
"The ladies at the desk and in the dinner area were great!"
Reviewed on 31 May 2026

Hampton Inn Sikeston
1240 Commerce Drive Sikeston MO
Fully refundableReserve now, pay when you stay
The price is AU$187 per night from 14 June to 15 June
AU$187
14 June - 15 June
includes taxes & fees
9/10 Wonderful! (573 reviews)
"The doughnuts and fry potatoes for breakfast were delicious"
Reviewed on 2 June 2026

Best Western Plus Sikeston I-55
120 S Interstate Drive Sikeston MO
Fully refundableReserve now, pay when you stay
The price is AU$145 per night from 28 June to 29 June
AU$145
28 June - 29 June
includes taxes & fees
8.4/10 Very Good! (1,004 reviews)
"Very convenient and staff was great."
Reviewed on 2 June 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.











