
Sikeston Holidays
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Your Sikeston Holiday
With a reputation for its rich history and rural countryside, Sikeston is an ideal getaway destination. Lock in one of our Sikeston holiday packages and discover all that this lively city has to offer. Fill your schedule with tours of The Book Bug, Sikeston Depot Museum and Central Park, some of the attractions you should see during a trip to Sikeston. Expedia can help you escape your routine. Tailor your holiday to Sikeston to suit your style of travel, whatever that may be!
Sikeston Holiday
Sikeston Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Cape Girardeau Municipal Airport (CGI) |
Population | 16,400 |
Max Temp Winter | 7ºC |
Max Temp Summer | 29ºC |
Top Sights | Sikeston Depot Museum, Central Park and The Book Bug |
Our pick of the best Sikeston Hotel Deals

Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
Fully refundableReserve now, pay when you stay
The price is AU$152 per night from 8 Mar to 9 Mar
AU$152
8 Mar - 9 Mar
includes taxes & fees
9.4/10 Exceptional! (1,006 reviews)
Staff and hotel was amazing. Highly recommend!!!
Reviewed on 1 Mar 2026

Hampton Inn Sikeston
1240 Commerce Drive Sikeston MO
Fully refundableReserve now, pay when you stay
The price is AU$152 per night from 29 Mar to 30 Mar
AU$152
29 Mar - 30 Mar
includes taxes & fees
9/10 Wonderful! (493 reviews)
Good room and helpful staff
Reviewed on 2 Mar 2026

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
100 Matthews Lane Sikeston MO
Fully refundableReserve now, pay when you stay
The price is AU$105 per night from 3 Mar to 4 Mar
AU$105
3 Mar - 4 Mar
includes taxes & fees
8.4/10 Very Good! (745 reviews)
Nice hotel for the price very clean. Staff was noce. Smells good. I woll come back
Reviewed on 1 Mar 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.












