Name: Hampton Inn Sikeston
Price range: AU$167
Rating: 8.8

Photo by Ryan Coleman

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Your Sikeston Holiday

With a reputation for its rich history and rural countryside, Sikeston is an ideal getaway destination. Lock in one of our Sikeston holiday packages and discover all that this lively city has to offer. Fill your schedule with tours of The Book Bug, Sikeston Depot Museum and Central Park, some of the attractions you should see during a trip to Sikeston. Expedia can help you escape your routine. Tailor your holiday to Sikeston to suit your style of travel, whatever that may be!

Sikeston Holiday

Sikeston Essential Information

Language	English
Currency	U.S dollars
Closest Airport	Cape Girardeau Municipal Airport (CGI)
Population	16,400
Max Temp Winter	7ºC
Max Temp Summer	29ºC
Top Sights	Sikeston Depot Museum, Central Park and The Book Bug

Our pick of the best Sikeston Hotel Deals

Days Inn and Suites by Wyndham Sikeston

220 S Interstate Dr Sikeston MO

Fully refundableReserve now, pay when you stay

AU$111

30 Nov - 1 Dec

includes taxes & fees

7.2/10 Good! (1,000 reviews)

This was a really great stay, which was part of my long roadtrip. The hotel was right off the interstate & wasn't too noisy. My room was pretty big which I really enjoyed! The bed was super comfy. The front desk woman was super friendly and welcoming. I was able to get Door Dash to deliver to the ...

Reviewed on 18 Nov 2025

Drury Inn & Suites Sikeston, MO

2608 East Malone Ave, Miner Sikeston MO

Fully refundableReserve now, pay when you stay

AU$160

1 Dec - 2 Dec

includes taxes & fees

9.4/10 Exceptional! (1,000 reviews)

Staff are wonderful, kind and welcoming! The happy hour is a great way to get out of your room and socialize. Lots of yummy food and drinks.

Reviewed on 17 Nov 2025

Hampton Inn Sikeston

1240 Commerce Drive Sikeston MO

Fully refundableReserve now, pay when you stay

AU$167

7 Dec - 8 Dec

includes taxes & fees

8.8/10 Excellent! (429 reviews)

Modern up to date facilities

Reviewed on 23 Nov 2025

See all 277 properties in Sikeston

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.