Top Hotels Near Sikeston Depot Museum in Sikeston from AU$94

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
6 Dec - 7 Dec
Tomorrow
7 Dec - 8 Dec
Next weekend
12 Dec - 14 Dec
In two weeks
19 Dec - 21 Dec

Filter by

Guest rating
Guest rating
Star rating

Accommodation near Sikeston Depot Museum

Bar (on property)
Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston

2.5 star property
2.4 km from Sikeston Depot Museum
9.4 out of 10, Exceptional, (38)
"THE ROOM WAS SPOTLESS, CLEAN LOBBY, WARM AND LOT OF VARITY BREAKFAST, STAFF IS SO NICE."
United States
AHMAD
The price is AU$173
includes taxes & fees
12 Dec - 13 Dec
Fairfield Inn & Suites by Marriott Sikeston
Exterior
Hampton Inn Sikeston

Hampton Inn Sikeston

2.5 star property
2.2 km from Sikeston Depot Museum
9.0 out of 10, Wonderful, (439)
"Room was clean and cozy, the check in-out staff were really nice and asked about our stay as well and the breakfast was a nice variety."
United States
Doncheial
The price is AU$162
includes taxes & fees
28 Dec - 29 Dec
Hampton Inn Sikeston
Bar (on property)
TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston

3.0 star property
2.4 km from Sikeston Depot Museum
9.0 out of 10, Wonderful, (8)
"Great hotel! Very clean, quiet, plenty of amenities, pool was clean, breakfast in the morning was good with lots of options. I would definitely stay here again. "
United States
Scott
The price is AU$201
includes taxes & fees
21 Dec - 22 Dec
TownePlace Suites by Marriott Sikeston
Exterior
Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG

2.5 star property
2.1 km from Sikeston Depot Museum
8.6 out of 10, Excellent, (443)
"Staff was great. Hotel was clean. Great sleep. "
United States
Jeffrey
The price is AU$159
includes taxes & fees
21 Dec - 22 Dec
Holiday Inn Express & Suites Sikeston Southwest by IHG
Lobby
Pear Tree Inn Sikeston

Pear Tree Inn Sikeston

2.5 star property
5 km from Sikeston Depot Museum
9.4 out of 10, Exceptional, (1002)
"Everything was clean, staff was friendly "
United States
Matthew
The price is AU$130
includes taxes & fees
31 Dec - 1 Jan 2026
Pear Tree Inn Sikeston
Property amenity
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3.0 star property
5.1 km from Sikeston Depot Museum
9.4 out of 10, Exceptional, (1001)
"Clean room, great location and friendly staff"
United States
Mark
The price is AU$156
includes taxes & fees
20 Dec - 21 Dec
Drury Inn & Suites Sikeston, MO
Exterior
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

2.5 star property
5 km from Sikeston Depot Museum
8.4 out of 10, Very good, (716)
"Stayed one night. Good rate for the Hotel "
United States
Paul
The price is AU$94
includes taxes & fees
31 Dec - 1 Jan 2026
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Exterior
Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55

2.5 star property
4.9 km from Sikeston Depot Museum
8.4 out of 10, Very good, (280)
"Room was clean, breakfast was very good. "
United States
Connie
The price is AU$144
includes taxes & fees
6 Jan - 7 Jan 2026
Comfort Inn & Suites Sikeston I-55
Room, 1 King Bed, Accessible, Non Smoking
Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area

2.0 star property
4.7 km from Sikeston Depot Museum
6.6 out of 10, (561)
"ALL GREAT"
United States
NELSON
The price is AU$100
includes taxes & fees
10 Dec - 11 Dec
Super 8 by Wyndham Sikeston/Miner Area
Free daily full breakfast
Best Western Plus Sikeston

Best Western Plus Sikeston

2.5 star property
5.4 km from Sikeston Depot Museum
8.4 out of 10, Very good, (1003)
"Nice location. Great staff. "
United States
Carla
The price is AU$125
includes taxes & fees
20 Dec - 21 Dec
Best Western Plus Sikeston
Iron/ironing board, free WiFi, bed sheets
Country Yard Inn and Suite

Country Yard Inn and Suite

2.0 star property
5.5 km from Sikeston Depot Museum
6.8 out of 10, (118)
"Great spot en route home from Mississippi. Staff put me in a room that ended up being in a quiet section of the hotel. Great sleep."
United States
Andrew
The price is AU$96
includes taxes & fees
7 Dec - 8 Dec
Country Yard Inn and Suite
1 bedroom, desk, laptop workspace, blackout curtains
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

2.0 star property
5.4 km from Sikeston Depot Museum
7.2 out of 10, Good, (1001)
"A great stay in every aspect. "
United States
Gertrude
The price is AU$108
includes taxes & fees
4 Jan - 5 Jan 2026
Days Inn and Suites by Wyndham Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Sikeston Depot Museum Hotel Reviews

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

10/10 Excellent
"Clean big room, great staff"
Dave 1-night trip
Posted 6 days ago
Drury Inn & Suites Sikeston, MO

Hotels near other Sikeston Depot Museum attractions

Central Park

3.8/5 (36 reviews)
Explore the great outdoors at Central Park, a lovely green space in Sikeston. While in this relaxing area, you can savour the top-notch restaurants.
See properties

City of Miner Convention Center

Learn about the events happening in City of Miner Convention Center during your trip to Miner. While in this relaxing area, you can savour the top-notch restaurants.
See properties

Frequently asked questions

What's the area like around Sikeston Depot Museum?
Sikeston Depot Museum is located in a welcoming area of Sikeston known for its array of dining options. You'll find 15 hotels and other accommodations within a few miles for a convenient home base.
What's the best place to stay near Sikeston Depot Museum?
Hampton Inn Sikeston is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an indoor pool. It's located 1.4 mi (2.2 km) from Sikeston Depot Museum. Other good choices within 5 miles include Drury Inn & Suites Sikeston, MO and Fairfield Inn & Suites by Marriott Sikeston.
How many hotels will I find close to Sikeston Depot Museum?
Expedia has 15 hotels and other accommodation options a few miles from Sikeston Depot Museum.
If I need to cancel the hotel reservation for my stay near Sikeston Depot Museum, will I receive a refund?
Yes! The majority of hotel room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you have a non-refundable reservation, you might be able to still cancel and get a refund within a 24-hour period of booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to view the best options available near Sikeston Depot Museum.