Travelers find the perfect blend of comfort at this Sikeston hotel where fitness enthusiasts work out, book lovers browse, and everyone enjoys attentive service
Choose dates to view prices
Photo gallery for Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham Sikeston welcomes guests with convenient to-go breakfast and in-room WiFi. The property offers laundry facilities, a gym for active travelers, and a library for quiet moments. Visitors consistently praise the staff's exceptional helpfulness.
Sikeston is home to Days Inn and Suites by Wyndham Sikeston. The area's natural beauty can be seen at Mississippi River and Central Park, while Sikeston Depot Museum and Front Street Studio & Art Gallery are cultural highlights. Visit our Sikeston travel guide
220 S Interstate Dr, Sikeston, MO, 63801
What's nearby
Southeast Missouri State University
33 min drive - 61.6 km
City of Miner Convention Center
13 min walk - 1.1 km
Central Park
5 min drive - 5.9 km
Saint Francis Medical Center
28 min drive - 57.5 km
Isle Casino Cape Girardeau
33 min drive - 60.8 km
Getting around
Cape Girardeau, MO (CGI-Cape Girardeau Municipal)
30 min drive
Restaurants
Lambert's Cafe
4 min drive
Buffalo Wild Wings
7 min drive
Burger King
6 min drive
Starbucks
8 min drive
Imo's Pizza
8 min drive
About this property
Days Inn and Suites by Wyndham Sikeston
Hotel remodelled in 2023
Take advantage of free on-the-go breakfast, a library and laundry facilities at Days Inn and Suites by Wyndham Sikeston. In addition to a gym, guests can connect to free in-room WiFi.
You'll also find perks such as:
Free self-parking
A 24-hour front desk, smoke-free property and a lift
Books, luggage storage and a banquet hall
Guest reviews say great things about the helpful staff
Room features
All 60 rooms feature comforts such as laptop-friendly workspaces and air conditioning, as well as thoughtful touches such as free WiFi and desk chairs. Guest reviews highly rate the cleanliness rooms at the property.
Free on-the-go breakfast available daily 6:00 AM to 9:00 AM
Things to do
Books
Gym
Library
Family friendly
In-room microwave
In-room refrigerator
In-room sofa bed
Laundry facilities
Living room
Separate bedroom
Conveniences
24-hour front desk
Laundry facilities
Luggage storage
Vending machine
Guest services
Housekeeping on request
Business services
3 meeting rooms
Accessibility
If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
Hardwood flooring in room
Lift
Wheelchair-accessible path to lift
More
2 floors
At least 80% lighting from LEDs
Banquet hall
Colonial architecture
Double-glazed windows
Renovated entire property - December 2023
Smoke-free property
Room amenities
Bedroom
Bedsheets provided
Blackout drapes
Sofa bed
Bathroom
Bathtub
Free toiletries
Hair dryer
Private bathroom
Towels provided
Entertainment
43-inch TV with satellite channels
Food and drink
Microwave
Refrigerator
More
Air conditioning
Desk
Desk chair
Free local calls
Heating
Iron/ironing board
Laptop workspace
LED lighting
Living room
Phone
Policies
Check-in
Check-in start time: 3:00 PM; check-in end time: 5:00 AM
Early check-in subject to availability
Early check-in fee: USD 40
Contactless check-in and check-out are available
Late check-in subject to availability
Minimum check-in age - 21
Check-out
Check-out before 11 AM
Special check-in instructions
Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools
Access methods
Staffed front desk
Pets
Pets are allowed for an extra charge of USD 20 per pet, per night
Service animals are welcome, and are exempt from fees
Welcoming dogs and cats only
2 total (up to 36 kg per pet)
Restrictions apply; for more information contact the property on the number on the booking confirmation
Children and extra beds
Children are welcome
Rollaway/extra beds are not available.
Cots (infant beds) are not available
Payment types
Important information
Fees
You'll be asked to pay the following charges at the property. Fees may include applicable taxes:
Deposit: USD 100 per accommodation, per stay
We have included all charges provided to us by the property.
Optional extras
Pet fee: USD 20 per pet, per night
Service animals are exempt from fees
Early check-in fee: USD 40 (subject to availability)
The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.
You need to know
Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards, debit cards and cash
Safety features at this property include a fire extinguisher
This property affirms that it follows the cleaning and disinfection practices of Count on Us (Wyndham)
Masks are required at the property for guests who have not received COVID-19 vaccination
Property is also known as
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Days Inn and Suites by Wyndham Sikeston Hotel
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Frequently asked questions
Is Days Inn and Suites by Wyndham Sikeston pet-friendly?
Yes, Days Inn and Suites by Wyndham Sikeston allows cats and dogs (limit 2 total) with a maximum weight of up to 36 kg per pet. There's a fee of USD 20 per pet, per night. Service animals are exempt from fees. Some restrictions may apply, so please contact the property for more details.
How much does it cost to stay at Days Inn and Suites by Wyndham Sikeston?
As of 11 Mar 2026, prices found for a 1-night stay for 2 adults at Days Inn and Suites by Wyndham Sikeston on 19 Mar 2026 start from AU$109, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.
How much is parking at Days Inn and Suites by Wyndham Sikeston?
Self-parking is free at this property.
What time is check-in at Days Inn and Suites by Wyndham Sikeston?
Check-in start time: 3:00 PM; check-in end time: 5:00 AM. Early check-in is available for a fee of USD 40 (subject to availability). Late check-in is available during limited hours.
What time is check-out at Days Inn and Suites by Wyndham Sikeston?
Checkout is at 11 AM.
Where is Days Inn and Suites by Wyndham Sikeston located?
Situated in Sikeston, this hotel is 0.9 mi (1.5 km) from City of Miner Convention Center and within 6 miles (10 km) of Sikeston Depot Museum and Central Park. Front Street Studio & Art Gallery is 9.2 mi (14.8 km) away.
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Reviews
Days Inn and Suites by Wyndham Sikeston Reviews
7.2
Good
All reviews shown are from real guest experiences. Only travellers who have booked a stay with us can submit a review. We verify reviews according to our guidelines and publish all reviews, positive or negative.More informationOpens in a new window
Staff was very nice. Room layout with two separate rooms was appreciated, especially at this price point. Good bed and bedding. Not super high end or careful about the rehab, and the breakfast was a carb fest, but overall we still felt it was a very good value
This was a really great stay, which was part of my long roadtrip. The hotel was right off the interstate & wasn't too noisy. My room was pretty big which I really enjoyed! The bed was super comfy. The front desk woman was super friendly and welcoming. I was able to get Door Dash to deliver to the location so that was a plus! They had quite a lot of items for breakfast, so I was surprised about that for a Days Inn. Only thing I didn't like was lack of parking, but overall, I would definitely stay here again if I come back to the area.
Kayla at the front desk was very helpful and accommodating when I first arrived. The room was very generous in space, clean and comfortable. A very quiet place to spend a night after 12 hours on the saddle.
Honorio
Stayed 1 night in Oct 2025
6/10 Okay
Virgil
19 Oct 2025
Disliked: Property conditions & facilities
This is an older hotel that has seen its better days. Needs a serious update with lots of TLC. Tonight I was looking for a clean bed and some rest. That’s what I got.
Virgil
Stayed 1 night in Oct 2025
8/10 Good
Robin
23 July 2025
Liked: Cleanliness, staff & service, room comfort
Peaceful
Nice, quiet place for a good night’s sleep.
Beds were comfy and the room was huge and pretty clean.
This property is updated, fresh paint in the halls and alot of work has gone into this location. The bed is comfortable and there are plenty of pillows (4).
The staff and room were nice. I did not like that they actually took a deposit out of my account and put it back instead of just held it like other hotels I've been at.
jerri
Stayed 1 night in Jul 2025
8/10 Good
Candy
24 Mar 2024
Liked: Amenities
We enjoyed our stay was very clean and accommodating.