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Our top choices for Matthews hotels

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.6 out of 10, Exceptional, (1,002 reviews)
"Great place!"
United States
Jennifer
The price is AU$184
includes taxes & fees
15 July - 16 July
Drury Inn & Suites Sikeston, MO

Super 8 By Wyndham Marston

Super 8 By Wyndham Marston
2.0 star property
Marston
8.0 out of 10, Very good, (66 reviews)
"Clean room, The receptionist very friendly, good parking."
United States
Temera
The price is AU$116
includes taxes & fees
6 July - 7 July
Super 8 By Wyndham Marston

Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (586 reviews)
"Staff were great at Check in, room was clean, breakfast was good."
United States
Brandi
The price is AU$171
includes taxes & fees
26 July - 27 July
Hampton Inn Sikeston

New Orleans Inn Portageville

New Orleans Inn Portageville
2.5 star property
Portageville
8.0 out of 10, Very good, (782 reviews)
"Great stay with Great people, very clean and welcoming"
United States
Mircea
The price is AU$78
includes taxes & fees
6 July - 7 July
New Orleans Inn Portageville

Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (97 reviews)
"Great stay, kind staff, very clean property."
United States
Joni
The price is AU$179
includes taxes & fees
19 July - 20 July
Fairfield Inn & Suites by Marriott Sikeston

The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
2.5 star property
Charleston
6.8 out of 10, (418 reviews)
"It was not at all what I expected. The website showed a very good hotel. It was awful. I would not paid even $40/ night if I knew how awful it is. I felt bad for the ladies working on front desk."
United States
Soheila
The price is AU$120
includes taxes & fees
6 July - 7 July
The Riverstone Hotel Charleston-Sikeston

Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.6 out of 10, Excellent, (474 reviews)
"Only stayed one night, no complaints"
United States
Zachary
The price is AU$171
includes taxes & fees
2 Aug - 3 Aug
Holiday Inn Express & Suites Sikeston Southwest by IHG

Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very good, (1,001 reviews)
"Very convenient and staff was great."
United States
jeanne
The price is AU$139
includes taxes & fees
26 July - 27 July
Best Western Plus Sikeston I-55

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.6 out of 10, (646 reviews)
"Clean rooms,"
United States
Karl
The price is AU$95
includes taxes & fees
19 July - 20 July
Super 8 by Wyndham Charleston/Sikeston East MO

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 star property
Sikeston
8.4 out of 10, Very good, (794 reviews)
"I love it there."
United States
Sharika West
The price is AU$109
includes taxes & fees
6 July - 7 July
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston
3.0 star property
Sikeston
9.2 out of 10, Wonderful, (18 reviews)
"This hotel was great. Good location. Awesome staff. Hopefully I get the opportunity to stay here again."
United States
Jason
The price is AU$178
includes taxes & fees
12 July - 13 July
TownePlace Suites by Marriott Sikeston

Country Yard Inn and Suite

Country Yard Inn and Suite
2.0 star property
Sikeston
6.8 out of 10, (140 reviews)
"Enjoyed our stay. All the appliances worked and our air conditioner kept us cool! Will definitely stay here again!"
United States
Sheryl
The price is AU$92
includes taxes & fees
6 July - 7 July
Country Yard Inn and Suite

Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter
2.5 star property
Dexter
9.8 out of 10, Exceptional, (42 reviews)
"Great place to stay"
United States
Lauren
The price is AU$169
includes taxes & fees
19 July - 20 July
Hampton Inn By Hilton Dexter

Travel Inn Marston I-55 by Hotel O

Travel Inn Marston I-55 by Hotel O
2.5 star property
Marston
6.0 out of 10, (125 reviews)
"Quiet safe area."
United States
Frank
The price is AU$94
includes taxes & fees
5 July - 6 July
Travel Inn Marston I-55 by Hotel O

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston
2.0 star property
Sikeston
7.2 out of 10, Good, (1,000 reviews)
"Business friendly, clean room staff very friendly, accommodating."
United States
Janice
The price is AU$113
includes taxes & fees
3 Aug - 4 Aug
Days Inn and Suites by Wyndham Sikeston

Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very good, (298 reviews)
The price is AU$150
includes taxes & fees
27 July - 28 July
Comfort Inn & Suites Sikeston I-55

Travelodge by Wyndham Dexter

Travelodge by Wyndham Dexter
2.0 star property
Dexter
7.6 out of 10, Good, (413 reviews)
"Clean room, staff was super helpful"
United States
Katherine
The price is AU$146
includes taxes & fees
5 July - 6 July
Travelodge by Wyndham Dexter

Dexter Inn

Dexter Inn
2.5 star property
Dexter
7.0 out of 10, Good, (353 reviews)
"Nice rooms, friendly staff, "
United States
Sarah
The price is AU$97
includes taxes & fees
16 July - 17 July
Dexter Inn

Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area
2.0 star property
Sikeston
7.0 out of 10, Good, (656 reviews)
"Staff is great rooms clean no bugs and bed was comfortable "
United States
James
The price is AU$103
includes taxes & fees
26 July - 27 July
Super 8 by Wyndham Sikeston/Miner Area

Econo Lodge Dexter

Econo Lodge Dexter
2.0 star property
Dexter
6.8 out of 10, (270 reviews)
"Air was not cold, bathroom door did not close, not a good selection for breakfast"
United States
Amanda
The price is AU$83
includes taxes & fees
3 Aug - 4 Aug
Econo Lodge Dexter
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Matthews Hotel Reviews

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Frequently asked questions

Where is the best place for a stay in Matthews?
Drury Inn & Suites Sikeston, MO, located 9.7 mi (15.5 km) from the heart of Matthews, is a top choice for your stay, based on our traveller data. Other good choices for your trip to the area are Days Inn and Suites by Wyndham Sikeston and Best Western Plus Sikeston I-55. See all available top hotels, or vacation rentals in Matthews.
What are some of the best holiday rentals that Matthews has to offer?
Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy: This holiday home rental outside of Matthews offers a fireplace, a balcony and a BBQ to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. You can relax into your holiday with a garden and a selection of games. See all vacation rentals in Matthews.
If I need to cancel my hotel reservation in Matthews, will I receive a refund?
Yes, you'll find most hotel bookings are fully refundable if cancelled prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you may still be able to cancel and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Matthews.
How is it to stay in Matthews?
Travellers to Matthews will find plenty to explore and enjoy. There are 40 hotels and other accommodation options in the surrounding area. Find out more about Matthews.
What are the top places to visit in Matthews?
Places to visit in the wider area include Central Park, Sikeston Depot Museum and Front Street Studio & Art Gallery. You'll also find Big Oak Tree State Park and Hunter-Dawson State Historic Site in the area. Take a look at what more there is to see and do in Expedia's Matthews guide.
What's the seasonal weather in Matthews?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Matthews is 1533 mm.