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Check prices for these dates

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30 Dec - 31 Dec
Tomorrow
31 Dec - 1 Jan
This weekend
2 Jan - 4 Jan
Next weekend
9 Jan - 11 Jan

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Our top choices for Santa Cruz hotels

Couples treatment room(s), hot stone massages, Thai massages
Isak Hotel & Golf Airport

Isak Hotel & Golf Airport

Isak Hotel & Golf Airport
3.0 star property
Rionegro
9.4 out of 10, Exceptional, (555)
"Bed clean and comfortable enough"
United States
Brian
Travelling for leisure
The price is AU$103
13 Jan - 14 Jan 2026
Isak Hotel & Golf Airport
Reception
Hotel Santiago de Arma

Hotel Santiago de Arma

Hotel Santiago de Arma
3.0 star property
Rionegro
9.2 out of 10, Wonderful, (914)
"Nice hotel, close to thee airport, convenient for an overnight stay"
United States
Ketankumar
Hotel Santiago de Arma
4 restaurants, breakfast served
Dann Carlton Medellin Hotel

Dann Carlton Medellin Hotel

Dann Carlton Medellin Hotel
4.5 star property
El Poblado
8.8 out of 10, Excellent, (1696)
"Clean rooms, great breakfast and amazing staff"
United States
Ayman
Travelling for business
The price is AU$134
12 Jan - 13 Jan 2026
Dann Carlton Medellin Hotel
Couples treatment room(s), sauna, hot tub, Turkish bath/hammam
Movich Hotel Las Lomas

Movich Hotel Las Lomas

Movich Hotel Las Lomas
4.0 star property
Rionegro
9.0 out of 10, Wonderful, (1011)
"the bed was very comfortable"
United States
Mariam
Travelling for leisure
The price is AU$218
13 Jan - 14 Jan 2026
Movich Hotel Las Lomas
32-inch LED TV with satellite channels, TV
Hotel San Fernando Plaza

Hotel San Fernando Plaza

Hotel San Fernando Plaza
4.0 star property
El Poblado
9.2 out of 10, Wonderful, (1000)
"Room was clean and friendly staff"
United States
Elvis
Travelling for leisure
The price is AU$156
21 Jan - 22 Jan 2026
Hotel San Fernando Plaza
Superior Double Room, 1 Queen Bed
Hotel Lagoon

Hotel Lagoon

Hotel Lagoon
3.5 star property
Rionegro
9.2 out of 10, Wonderful, (302)
"Brand new hotel Very clean Close to the airport excellent dining options near by."
United States
JUAN
Travelling with partner
The price is AU$201
6 Jan - 7 Jan 2026
Hotel Lagoon
Grand Studio | Living area
Calle Flora Hotel by Jalo

Calle Flora Hotel by Jalo

Calle Flora Hotel by Jalo
3.5 star property
El Poblado
9.2 out of 10, Wonderful, (333)
"great staff, clean rooms, beautiful property"
United States
Jose
The price is AU$108
13 Jan - 14 Jan 2026
Calle Flora Hotel by Jalo
Breakfast, lunch, dinner served; American cuisine
Hotel Park 10

Hotel Park 10

Hotel Park 10
4.0 star property
El Poblado
9.2 out of 10, Wonderful, (1234)
"The room was very spacious, clean and good mattress"
United States
Edgar
Travelling for leisure
The price is AU$119
9 Jan - 10 Jan 2026
Hotel Park 10
Restaurant
Hashtag 98 Hotel By Jalo

Hashtag 98 Hotel By Jalo

Hashtag 98 Hotel By Jalo
4.0 star property
El Poblado
9.2 out of 10, Wonderful, (1659)
"The rooms were modern, clean, comfortable beds, great Wi-Fi and had amazing city views."
United States
Emely
Travelling for leisure
The price is AU$167
7 Jan - 8 Jan 2026
Hashtag 98 Hotel By Jalo
Outdoor pool, open 6 AM to 8 PM, pool loungers
Novotel Medellín El Tesoro

Novotel Medellín El Tesoro

Novotel Medellín El Tesoro
4.5 star property
El Poblado
9.4 out of 10, Exceptional, (1365)
"Love the room and the view was amazing, the mall was huge and beautiful."
United States
Jessenia
Travelling for leisure
The price is AU$209
4 Jan - 5 Jan 2026
Novotel Medellín El Tesoro
Exterior
The Charlee Hotel

The Charlee Hotel

The Charlee Hotel
5.0 star property
El Poblado
8.8 out of 10, Excellent, (1004)
"Excellent location, with many dining options and entertainment in very close proximity."
United States
Roger
Travelling with partner
The price is AU$300
5 Jan - 6 Jan 2026
The Charlee Hotel
Restaurant
The Click Clack Hotel Medellin

The Click Clack Hotel Medellin

The Click Clack Hotel Medellin
5.0 star property
El Poblado
9.2 out of 10, Wonderful, (1076)
"Great location, nice bars and restaurants, comfy beds, and very friendly staff!"
United States
Nick
Travelling with partner
The price is AU$309
20 Jan - 21 Jan 2026
The Click Clack Hotel Medellin
Outdoor pool, pool umbrellas
Hotel Dann Carlton Belfort Medellin

Hotel Dann Carlton Belfort Medellin

Hotel Dann Carlton Belfort Medellin
4.0 star property
El Poblado
8.8 out of 10, Excellent, (1002)
"the room was great too with an amazing view!"
United States
Amado
Travelling solo
The price is AU$121
12 Jan - 13 Jan 2026
Hotel Dann Carlton Belfort Medellin
Deluxe Double Room
Hunters By Jalo

Hunters By Jalo

Hunters By Jalo
3.0 star property
El Poblado
9.0 out of 10, Wonderful, (224)
"Room is decent, very clean."
United States
Maria
Travelling with partner
The price is AU$90
8 Jan - 9 Jan 2026
Hunters By Jalo
Indoor pool, outdoor pool, pool loungers
York Medellin, Curio Collection by Hilton

York Medellin, Curio Collection by Hilton

York Medellin, Curio Collection by Hilton
4.0 star property
El Poblado
9.6 out of 10, Exceptional, (1428)
"My room was so spacious and nice."
United States
Catherine
Travelling with friends
The price is AU$193
13 Jan - 14 Jan 2026
York Medellin, Curio Collection by Hilton
Outdoor pool, pool umbrellas, pool loungers
NH Collection Medellín Royal

NH Collection Medellín Royal

NH Collection Medellín Royal
5.0 star property
El Poblado
9.2 out of 10, Wonderful, (1000)
"Good selection of foods for breakfast and nice gym."
United Kingdom
Beena
Travelling with partner
The price is AU$171
11 Jan - 12 Jan 2026
NH Collection Medellín Royal
Arcade
Diez Hotel Categoria Colombia

Diez Hotel Categoria Colombia

Diez Hotel Categoria Colombia
4.0 star property
El Poblado
9.4 out of 10, Exceptional, (1008)
"Great, clean rooms and wonderful staff."
United States
Lourdes
Travelling for leisure and business
The price is AU$172
13 Jan - 14 Jan 2026
Diez Hotel Categoria Colombia
Terrace/patio
Landmark Hotel

Landmark Hotel

Landmark Hotel
4.0 star property
El Poblado
9.6 out of 10, Exceptional, (232)
"The rooms are spacious, stylish, and very clean"
United States
Estefania
Travelling with partner
The price is AU$196
31 Jan - 1 Feb 2026
Landmark Hotel
Suite, 1 King Bed (Upper Floor)
V Grand Hotel, a member of Radisson Individuals

V Grand Hotel, a member of Radisson Individuals

V Grand Hotel, a member of Radisson Individuals
3.5 star property
El Poblado
9.2 out of 10, Wonderful, (1283)
"Rooms are spacious and clean not too much noise which is good"
United States
Sasha
Travelling for leisure
The price is AU$143
14 Jan - 15 Jan 2026
V Grand Hotel, a member of Radisson Individuals
Dining
Travelers Rio Verde Living Suites

Travelers Rio Verde Living Suites

Travelers Rio Verde Living Suites
3.5 star property
Rionegro
8.4 out of 10, Very good, (466)
"it is a good location conveniently close to the airport"
United States
Jan
Travelling with partner
Travelers Rio Verde Living Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Hotel Reviews

Recent Reviews in Santa Cruz

V Grand Hotel, a member of Radisson Individuals

V Grand Hotel, a member of Radisson Individuals

10/10 Excellent
"Room and staff are good"
SAI KIRAN 5-night trip
Posted 1 day ago
V Grand Hotel, a member of Radisson Individuals

More cheap accommodation in Santa Cruz

Hotel Villanueva Comfort

Hotel Villanueva Comfort

57-12 Cra. 49 Medellín Antioquia
The price is AU$75 per night from 8 Jan to 9 Jan
AU$75
8 Jan - 9 Jan 2026
8.6/10 Excellent! (29 reviews)

Frequently asked questions

Where is the best place to stay in Santa Cruz?
Located 5.9 mi (9.4 km) from the heart of Santa Cruz, Heiss Hotel By Jalo is a top choice for your stay, based on our traveller data. Two other options for your stay in the area are Calle Flora Hotel by Jalo and York Medellin, Curio Collection by Hilton. See all available top hotels, or vacation rentals in Santa Cruz.
What are some of the best holiday rentals that Santa Cruz has to offer?
La Gracia Hotel & Spa: This holiday home rental outside of Santa Cruz offers a terrace, a garden and free WiFi to help you feel perfectly comfortable in your new surroundings. See all vacation rentals in Santa Cruz.
If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?
Yes! Most hotel bookings are fully refundable if you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you might be able to cancel it and receive a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.
What is staying in Santa Cruz like?
Visitors will definitely enjoy all that Santa Cruz has to offer. In Santa Cruz, there are 3 hotels and other accommodation options to choose from. Find out more about Santa Cruz.
What should I do while I'm visiting Santa Cruz?
Places to visit in the wider area include Medellin Botanical Garden, Explora Park and Arvi Park. You'll also find Antioquia Museum and Botero Plaza in the area. Take a look at what more there is to see and do in Expedia's Santa Cruz guide.
How can I get around Santa Cruz?
Make your way to Andalucía MetroCable Station for metro travel. If you want to venture out around the area, you may want a rental car in Santa Cruz for your journey.
What's the seasonal weather in Santa Cruz?
The hottest months are usually August and July, with an average temperature of 19°C, while the coldest months are December and January, with an average of 18°C. The rainiest months in Santa Cruz are May, April, October and November, with each month seeing an average of 406 mm of rainfall.

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