Santa Cruz Holidays

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Your Santa Cruz Holiday

From its highlights to its hidden treasures, this city is best explored with a Santa Cruz holiday package. Check out places to stay in La Candelaria, which is good for dining, history and shopping. Love to venture out and explore? Atanasio Giradot Stadium, Botero Plaza and Lights Park are a few of the best places to visit during your trip to Santa Cruz. Whoever you're escaping with and whatever your bank balance, your ultimate Santa Cruz holiday is just a few clicks away with Expedia.

Santa Cruz Holiday

Santa Cruz Essential Information

Language
Spanish
Currency
Colombian pesos
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Jose Maria Cordova Intl. Airport (MDE)
Max Temp Winter
21ºC
Max Temp Summer
24ºC
Top Sights
Pueblito Paisa, Explora Park and Antioquia Museum

Our pick of the best Santa Cruz Hotel Deals

Heiss Hotel By Jalo

Heiss Hotel By Jalo

4 out of 5
1460 Cra. 43F Medellín Antioquia
Fully refundableReserve now, pay when you stay
The price is AU$126 per night from 14 Dec to 15 Dec
AU$126
14 Dec - 15 Dec
9/10 Wonderful! (959 reviews)
Excellent staff, great environment and an amazing view from the patio.

Reviewed on 14 Nov 2025

Heiss Hotel By Jalo
Hotel Dorado La 70

Hotel Dorado La 70

4 out of 5
Carrera 70 No 44 B-66 Medellín
Fully refundableReserve now, pay when you stay
The price is AU$171 per night from 20 Nov to 21 Nov
AU$171
20 Nov - 21 Nov
8.8/10 Excellent! (1,714 reviews)
excellent

Reviewed on 11 Nov 2025

Hotel Dorado La 70
York Luxury Suites Medellín

York Luxury Suites Medellín

4 out of 5
Carrera 43a 17sur 63 Medellín Antioquia
Fully refundableReserve now, pay when you stay
The price is AU$246 per night from 16 Dec to 17 Dec
AU$246
16 Dec - 17 Dec
9.4/10 Exceptional! (1,393 reviews)
Spotless

Reviewed on 13 Nov 2025

York Luxury Suites Medellín
See all 4,361 properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
All Inclusive Holidays
Cheap Holidays
Cheap Holidays
Cheap Holidays
beach holidays
Beach Holidays
Beach Holidays

Discover the most popular places to visit in Santa Cruz

Pueblito Paisa showing religious elements and a church or cathedral

Pueblito Paisa

4.5/5(2 reviews)

Visit this replica of an early 20th-century town to experience old-world Colombia and to get amazing views of Medellín.

Pueblito Paisa

Poblado Park

3/5(2 reviews)

After visiting Poblado Park, make a plan to see the other sights and activities in Medellín. Visit the shops and top-notch restaurants in this walkable area.

Poblado Park

Hospital Pablo Tobon Uribe

If Hospital Pablo Tobon Uribe is what brings you to town, hopefully you'll have a chance to explore more of Medellín.

Hospital Pablo Tobon Uribe

What to do in Santa Cruz

Day Trip To Guatapé with ,Breakfast, Lunch and Boat Ride

Day Trip To Guatapé with ,Breakfast, Lunch and Boat Ride

AU$52
per adult
96% of travellers recommend
Day Trip To Guatapé with ,Breakfast, Lunch and Boat Ride
Medellín: Comuna 13 District Tour with Cable Car Ride

Medellín: Comuna 13 District Tour with Cable Car Ride

AU$31
per adult
96% of travellers recommend
Medellín: Comuna 13 District Tour with Cable Car Ride
See all activities in Santa Cruz

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.