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Santa Cruz Holiday Rentals

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Our top choices for Santa Cruz holiday rentals

1. Skyline Ecoliving

Skyline Ecoliving
3.0 star property
El Rosario
9.4 out of 10, Exceptional, (43 reviews)
"Exelente servicio"
United States
Ernesto
The price is AU$104
11 Aug - 12 Aug
Skyline Ecoliving

2. B 48 Living by B Rent

B 48 Living by B Rent
4.0 star property
Laureles - Estadio
9.8 out of 10, Exceptional, (21 reviews)
"I love the people & I love the area. One of the best place to stay in Medellin. "
United States
Lusene
The price is AU$81
5 Aug - 6 Aug
B 48 Living by B Rent

3. Edificio Helena

Edificio Helena
3.0 star property
Medellín
8.8 out of 10, Excellent, (65 reviews)
"Awesome breakfast, great location. Great host"
United States
James
The price is AU$54
2 Sept - 3 Sept
Edificio Helena

4. Metropolitan Living by HOUSY

Metropolitan Living by HOUSY
4.0 star property
San Diego
9.2 out of 10, Wonderful, (77 reviews)
"Good😀😀😀😀"
United States
Percy
The price is AU$102
24 Aug - 25 Aug
Metropolitan Living by HOUSY

5. Nomadic Boutique Living and Experience Center

Nomadic Boutique Living and Experience Center
4.0 star property
El Poblado
9.8 out of 10, Exceptional, (25 reviews)
"The day staff was amazing, the included breakfast was the best I’ve had! The space was perfect!"
United States
Carolina
The price is AU$74
10 Aug - 11 Aug
Nomadic Boutique Living and Experience Center

6. Portal del Rodeo ApartaHotel - Arkadia Mall

Portal del Rodeo ApartaHotel - Arkadia Mall
3.5 star property
Medellín
9.0 out of 10, Wonderful, (288 reviews)
"Excellent place to stay with family and friends!"
Canada
Jose
The price is AU$109
15 Aug - 16 Aug
Portal del Rodeo ApartaHotel - Arkadia Mall

7. Factory Lofts

Factory Lofts
4.0 star property
Laureles - Estadio
9.8 out of 10, Exceptional, (135 reviews)
"All the staff were absolutely great with a special thanks to Andres and Santiago! The cleaning was great and the location very convenient to everything and honestly a lot quieter than most of Calle 70.. Would definitely recommend and hope to visit soon"
United States
Firas Ghazi
The price is AU$179
1 Sept - 2 Sept
Factory Lofts

8. Hotel Distrito 70 Living

Hotel Distrito 70 Living
3.0 star property
Laureles - Estadio
9.6 out of 10, Exceptional, (5 reviews)
"Clean room, the breakfast was good but it was in another location"
United States
Ricardo
The price is AU$65
1 Sept - 2 Sept
Hotel Distrito 70 Living

9. Luxury Suites Prana By Cadissa

Luxury Suites Prana By Cadissa
5.0 star property
Laureles - Estadio
9.2 out of 10, Wonderful, (51 reviews)
"It was very easy to check in and out. The apartment had everything we needed to be comfortable. The location was great. We were able to walk around and felt very safe. I highly recommend it if you are looking for an affordable place with good customer service and cleanliness."
United States
Mahely
The price is AU$194
31 Aug - 1 Sept
Luxury Suites Prana By Cadissa

10. Origen Local Suites

Origen Local Suites
3.0 star property
Laureles
9.4 out of 10, Exceptional, (211 reviews)
"Great place.!"
United States
jeremy
The price is AU$89
2 Sept - 3 Sept
Origen Local Suites

11. Loft 43

Loft 43
3.0 star property
Laureles
8.6 out of 10, Excellent, (33 reviews)
"Fabulous room with floor to ceiling windows, comfortable bed, hot water in the shower and a strong wifi connection. Close to Estadio metro station and La Setenta for food and nightlife. Staff were friendly and check-in was fast. Light sleepers might find the neighborhood a bit loud. There are many local restaurants along Calle 43 (just head away from La 70) for lunch and dinner."
United States
Daniel
The price is AU$81
2 Sept - 3 Sept
Loft 43

12. Haven, A Design Hotel

Haven, A Design Hotel
4.0 star property
El Poblado
8.8 out of 10, Excellent, (713 reviews)
"The entire staff from the doorman, reception, housekeeper, bartender, and cooks are all so very welcoming."
United States
robert
The price is AU$147
17 Aug - 18 Aug
Haven, A Design Hotel

13. Hotel Moore 45

Hotel Moore 45
4.0 star property
Buenos Aires
8.8 out of 10, Excellent, (3 reviews)
"I like the service and it’s really comfortable. And the people in their recession. Bety. Help. Take you guys. I Enjoy the State. I’m planning to Come Back. How old is go back to the hotel again!"
United States
Welinton
The price is AU$34
10 Aug - 11 Aug
Hotel Moore 45

14. Seissta Medellin

Seissta Medellin
4.0 star property
El Poblado
9.4 out of 10, Exceptional, (266 reviews)
"Very Clean and Friendly Staff."
United States
Paul
The price is AU$136
25 Aug - 26 Aug
Seissta Medellin

15. Quadrato Studios

Quadrato Studios
3.0 star property
Laureles
9.4 out of 10, Exceptional, (108 reviews)
"Beautiful hotel great location great breakfast"
United States
gary
The price is AU$72
1 Sept - 2 Sept
Quadrato Studios

16. Casa Museo by HOUSY

Casa Museo by HOUSY
3.5 star property
Laureles
8.4 out of 10, Very good, (5 reviews)
"I highly recommend staying here. It’s centrally located, comfortable, clean, and the service is excellent."
United States
Carlos
The price is AU$112
30 Aug - 31 Aug
Casa Museo by HOUSY

17. Kyux by Jalo

Kyux by Jalo
4.0 star property
Laureles
9.2 out of 10, Wonderful, (141 reviews)
"Excellent place to stay."
United States
Rexford
The price is AU$100
16 Aug - 17 Aug
Kyux by Jalo

18. Laureles Guest House - LGH Hotel

Laureles Guest House - LGH Hotel
3.5 star property
Laureles
9.2 out of 10, Wonderful, (100 reviews)
"Excellent breakfast, good location "
United States
dickie
The price is AU$64
17 Aug - 18 Aug
Laureles Guest House - LGH Hotel

19. Living by Armoniko

Living by Armoniko
4.0 star property
Laureles
9.4 out of 10, Exceptional, (73 reviews)
"We liked the location and that they have parking on their property."
United States
Richard
The price is AU$168
31 Aug - 1 Sept
Living by Armoniko

20. zenia

zenia
3.0 star property
Laureles
9.4 out of 10, Exceptional, (56 reviews)
"Room was perfect, if you’re staying for a long trip, I highly recommend getting the room with the washer. Super clean and amazing location."
United States
Kirman
The price is AU$43
12 Aug - 13 Aug
zenia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Hotel Reviews

Find out more about Santa Cruz

Everything you need to know about Santa Cruz holiday rentals

Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the Santa Cruz holiday rental for you. At Expedia, you can take your pick from private holiday homes, apartments, cottages, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santa Cruz holiday rental for you by simply entering your desired dates. Then check your favourite filters to narrow down your search. 

Santa Cruz holiday rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santa Cruz. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depend on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Santa Cruz holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Santa Cruz holiday rentals we have selected for you start as low as AU$43 per night. Entering your travel dates in the search wizard might find you even better deals!

How to find incredible deals on Santa Cruz rentals

At Expedia, we put the best Santa Cruz holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top Santa Cruz rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santa Cruz holiday.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santa Cruz. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. 

Frequently asked questions

Can I find a holiday rental in Santa Cruz?

Yes, there are holiday rentals close to the most popular sights in Santa Cruz, or you can select a more secluded option if you're looking for a relaxing stay.

What are some of the best holiday rentals that Santa Cruz has to offer?

La Gracia Hotel & Spa: This holiday home rental outside Santa Cruz offers a terrace, a garden and free WiFi to help you feel perfectly comfortable in your new surroundings.

What’s there to see and do in Santa Cruz?

While exploring the area, visit family-friendly sights like Pueblito Paisa, or get outside and enjoy nature at Lleras Park. In the wider area, you’ll find Medellin Botanical Garden and University of Antioquia.

What’s a holiday rental in Santa Cruz like?

Holiday rentals are private properties where you can stay for a few weeks, or just a few days, in Santa Cruz. Holiday rentals offer extras like WiFi and washers and dryers so you'll feel right at home. If you're concerned about a clean environment, holiday rentals can offer a sense of safety away from public hotel lifts and lobbies bustling with people while still allowing you the enjoyment of travel. You'll also find more space in a holiday rental than in a standard hotel, which is another reason why a holiday rental is a popular option for families.