Santa Cruz Holiday Rentals

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Check prices for these dates

In two weeks
19 Dec - 21 Dec
In two months
30 Jan - 1 Feb
In three months
27 Feb - 1 Mar
In four months
27 Mar - 29 Mar

Holiday Rentals in Santa Cruz

Indoor pool, outdoor pool, pool loungers
York Luxury Suites Medellín

Aparthotel in El Poblado

4.0 star property
9.6 out of 10, Exceptional, (1412)
"Great place to stay !"
United States
Lendsey
The price is AU$262
8 Dec - 9 Dec
York Luxury Suites Medellín
Pool
Sites Hotel

Aparthotel in El Poblado

4.0 star property
9.2 out of 10, Wonderful, (1098)
"Breakfast had a few options and air conditioning was good , staff was pleasant and helpful "
United States
Hilda
The price is AU$138
16 Dec - 17 Dec
Sites Hotel
Lobby
Haven

Aparthotel in El Poblado

4.0 star property
8.8 out of 10, Excellent, (633)
"Great location"
United States
Keegan
The price is AU$154
8 Dec - 9 Dec
Haven
Outdoor spa tub
Metropolitan Living by HOUSY

Apartment in San Diego

4.0 star property
9.6 out of 10, Exceptional, (17)
"Great location."
United States
Nekitta
The price is AU$107
8 Dec - 9 Dec
Metropolitan Living by HOUSY
Basic Studio Suite, City View | Terrace/patio
Royal Living Poblado

Apartment in El Poblado

4.0 star property
9.2 out of 10, Wonderful, (52)
"Great place"
United States
Dante
Royal Living Poblado
Loft, 1 Double Bed
Factory Lofts

Aparthotel in Laureles - Estadio

4.0 star property
9.8 out of 10, Exceptional, (103)
"Amazingly hotel and friendly front desk staff. Room is very clean and spacious and the area is very safe too."
United States
Raymond
The price is AU$121
8 Dec - 9 Dec
Factory Lofts
Outdoor spa tub
Quadrato Studios

Apartment in Laureles

3.0 star property
9.6 out of 10, Exceptional, (76)
"Great stay, will repeat"
United States
Ignacio
Quadrato Studios
Standard Twin Room, 1 Single Bed (Superior Apartment Twin Bed)
Estelar Apartamentos Medellin

Aparthotel in El Poblado

3.5 star property
8.8 out of 10, Excellent, (454)
"The rooms look a bit aged but were very clean and great cleaning services It would be very helpful if the property stated in their page that visitors to the room have to pay a fee in order to go in the hotel Wouldn’t have booked it had I known that "
United States
Luis Eduardo
The price is AU$146
21 Dec - 22 Dec
Estelar Apartamentos Medellin
Standard Studio | Street view
Origen Local Suites

Apartment in Laureles

3.0 star property
9.4 out of 10, Exceptional, (186)
"A excellent stay very wonderful staff "
United States
gary
The price is AU$87
23 Dec - 24 Dec
Origen Local Suites
Studio Suite (102) | Television
Botánica Manila by HOUSY HOST

Aparthotel in El Poblado

3.0 star property
9.0 out of 10, Wonderful, (47)
"Very clean rooms and comfort! "
United States
chantal
The price is AU$109
16 Dec - 17 Dec
Botánica Manila by HOUSY HOST
Coffee shop
Apartment Go Living & Suites by HOUSY HOST

Apartment in El Poblado

3.5 star property
8.4 out of 10, Very good, (391)
"Clean space and very convenient "
United States
Andrae
The price is AU$142
6 Jan - 7 Jan 2026
Apartment Go Living & Suites by HOUSY HOST
Business Apartment
Kyux by Jalo

Apartment in Laureles

4.0 star property
9.6 out of 10, Exceptional, (55)
"Excellent stay and a great property. "
United States
Brijesh
The price is AU$84
8 Dec - 9 Dec
Kyux by Jalo
Dining
Travelers Rio Verde Living Suites

Condo in Rionegro

3.5 star property
8.2 out of 10, Very good, (461)
"Good property. "
United States
Ruth Marcela
Travelers Rio Verde Living Suites
Apartment, 1 Bedroom | Living area
Wake Living

Apartment in El Poblado

4.0 star property
8.8 out of 10, Excellent, (167)
"Great location best views"
United States
William
Wake Living
Restaurant
Seissta Medellin

Apartment in El Poblado

4.0 star property
9.2 out of 10, Wonderful, (206)
"Clean room and amazing staff"
United States
Collins
The price is AU$164
14 Dec - 15 Dec
Seissta Medellin
Lobby lounge
Laureles Guest House - LGH Hotel

Apartment in Laureles

3.5 star property
9.0 out of 10, Wonderful, (77)
"Good local foods"
United States
Howard
The price is AU$65
9 Dec - 10 Dec
Laureles Guest House - LGH Hotel
Staircase
zenia

Apartment in Laureles

3.0 star property
9.4 out of 10, Exceptional, (37)
"Very close to everything you need."
United States
Gabriel Martinez
The price is AU$39
18 Dec - 19 Dec
zenia
Apartment, Multiple Beds | Dining room
Portal del Rodeo ApartaHotel - Arkadia Mall

Aparthotel in Medellín

3.5 star property
9.0 out of 10, Wonderful, (247)
"Everything was good .. 👍 nice place to stay with family very safe.. nice people.."
United States
Seleidy
The price is AU$93
8 Dec - 9 Dec
Portal del Rodeo ApartaHotel - Arkadia Mall
Exclusive Apartment
GRES Apartamentos

Aparthotel in El Poblado

3.5 star property
10.0 out of 10, Exceptional, (6)
"Clean, close to everything, staff was amazing "
United States
Roberto
The price is AU$114
8 Dec - 9 Dec
GRES Apartamentos
Apartment, 3 Bedrooms (301)
HOUSY Laureles

Apartment in Laureles

4.0 star property
9.2 out of 10, Wonderful, (77)
"Staff was amazing! Staff on the Cattleya restaurant was also amazing and food was also great! Will be booking again! "
United States
Shajayra
The price is AU$177
31 Dec - 1 Jan 2026
HOUSY Laureles
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Hotel Reviews

Calle Flora Hotel by Jalo

Calle Flora Hotel by Jalo

10/10 Excellent
"the room was cozy and clean with all the necessary amenities. It does get a bit loud at night but some ear plugs (the hotel offers free ones) will definitley help. it is in great location to walking distance to bars and hotels."
Giselle 4-night trip
Posted 3 days ago
Calle Flora Hotel by Jalo

Find out more about Santa Cruz

Everything you need to know about Santa Cruz holiday rentals

Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the Santa Cruz holiday rental for you. At Expedia, you can take your pick from private holiday homes, apartments, cottages, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santa Cruz holiday rental for you by simply entering your desired dates. Then check your favourite filters to narrow down your search. 

Santa Cruz holiday rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santa Cruz. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depend on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Santa Cruz holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Santa Cruz holiday rentals we have selected for you start as low as AU$39 per night. Entering your travel dates in the search wizard might find you even better deals!

How to find incredible deals on Santa Cruz rentals

At Expedia, we put the best Santa Cruz holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top Santa Cruz rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santa Cruz holiday.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santa Cruz. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. 

Frequently asked questions

Can I find a holiday rental in Santa Cruz?

Yes, there are holiday rentals close to the most popular sights in Santa Cruz, or you can select a more secluded option if you're looking for a relaxing stay.

What are some of the best holiday rentals that Santa Cruz has to offer?

La Gracia Hotel & Spa: This holiday home rental outside of Santa Cruz offers a terrace, a garden and free WiFi to help you feel perfectly comfortable in your new surroundings.

What’s there to see and do in Santa Cruz?

While exploring the area, visit family-friendly sights like Pueblito Paisa, or get outside and enjoy nature at Medellin Botanical Garden. In the wider area, you’ll find University of Antioquia and Arvi Park.

What’s a holiday rental in Santa Cruz like?

Holiday rentals are private properties where you can stay for a few weeks, or just a few days, in Santa Cruz. Holiday rentals offer extras like WiFi and washers and dryers so you'll feel right at home. If you're concerned about a clean environment, holiday rentals can offer a sense of safety away from public hotel lifts and lobbies bustling with people while still allowing you the enjoyment of travel. You'll also find more space in a holiday rental than in a standard hotel, which is another reason why a holiday rental is a popular option for families.