Santa Cruz Holiday Rentals

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
In two months
In three months
In four months

Our top choices for Santa Cruz holiday rentals

PORTANOVA SUITES by ADVENTU

PORTANOVA SUITES by ADVENTU
3.0 star property
Rionegro
8.4 out of 10, Very good, (52 reviews)
"Room was very clean and apt is very quiet and close to the hospital "
United States
FERNANDO
The price is AU$78
13 May - 14 May
PORTANOVA SUITES by ADVENTU

Almaia 17

Almaia 17
3.0 star property
Rionegro
The price is AU$168
6 May - 7 May
Almaia 17

Hotel Moore 45

Hotel Moore 45
4.0 star property
Buenos Aires
8.0 out of 10, Very good, (1 review)
The price is AU$42
3 May - 4 May
Hotel Moore 45

Mali Experience

Mali Experience
3.0 star property
Rionegro
10.0 out of 10, Exceptional, (2 reviews)
"My room was a well-equipped luxury studio apartment that included a washer/dryer (what a treat) and a great small kitchen and a large walk-in shower. Absolutely loved my accommodation. And for you gringos and gringas out there with shaky Spanish, your host, Juan, not only speaks impeccable English but is so very helpful. Highly recommend!"
United States
Gabrielle
The price is AU$105
2 May - 3 May
Mali Experience

Shabbat Hotel Boutique

Shabbat Hotel Boutique
4.0 star property
San Vicente
10.0 out of 10, Exceptional, (2 reviews)
"Excelente Servicio y facilidades. 100% recomendado"
United States
william
The price is AU$163
14 May - 15 May
Shabbat Hotel Boutique

hotel civitas medellin

hotel civitas medellin
2.5 star property
La Candelaria
9.0 out of 10, Wonderful, (2 reviews)
"Hotel in a good location, comfortable and has a great staff."
United States
Valencia
The price is AU$34
3 May - 4 May
hotel civitas medellin

Casagrande

Casagrande
2.0 star property
Rionegro
6.0 out of 10, (2 reviews)
"Very nice large room with king size bed, very low noise beautiful Mountain View’s. It was a little cold for pool but, various shopping centers close to property and public transport passes right in front. Awesome place to stay."
United States
Alex
The price is AU$75
11 May - 12 May
Casagrande

Sky View Glamping

Sky View Glamping
2.0 star property
Girardota
9.0 out of 10, Wonderful, (2 reviews)
"Great view and the hospitality was very good.. The cabins were clean. "
United States
Chris
The price is AU$173
3 May - 4 May
Sky View Glamping

Casa Los Curazaos

Casa Los Curazaos
3.5 star property
Rionegro
8.0 out of 10, Very good, (1 review)
"Hermosa cabaña, a tan solo 1km de la via que conduce de LLanogrande a la Ceja. Sobria, bien decorada, con todo lo necesario para una corta estadia. "
Mexico
CARLOS
The price is AU$188
11 May - 12 May
Casa Los Curazaos

Candelaria Campestre

Candelaria Campestre
2.0 star property
El Carmen de Viboral
The price is AU$165
6 May - 7 May
Candelaria Campestre

Travelers Rio Verde Living Suites

Travelers Rio Verde Living Suites
3.5 star property
Rionegro
8.4 out of 10, Very good, (473 reviews)
"GOOD PLACE TO STAY THE NIGHT NEAR THE AIRPORT"
United States
Robert
The price is AU$112
1 May - 2 May
Travelers Rio Verde Living Suites

Hotel Rioverde- 5 minutos de cercanía al aeropuerto

Hotel Rioverde- 5 minutos de cercanía al aeropuerto
4.5 star property
Rionegro
7.4 out of 10, Good, (61 reviews)
"Clean room and good amenities. Close to the airport which was useful after a long flight "
Australia
DAVID
The price is AU$138
1 May - 2 May
Hotel Rioverde- 5 minutos de cercanía al aeropuerto

Onirico Luxury

Onirico Luxury
2.0 star property
Medellin
The price is AU$116
7 May - 8 May
Onirico Luxury

Edificio Helena

Edificio Helena
3.0 star property
Medellín
9.2 out of 10, Wonderful, (59 reviews)
"For being a last minute stay, this place was better than expected and highly recommended. The rooftop is has a spectacular view of Medellin. "
United States
Michael
The price is AU$54
31 May - 1 June
Edificio Helena

Skyline Ecoliving

Skyline Ecoliving
3.0 star property
El Rosario
9.2 out of 10, Wonderful, (42 reviews)
"Increíble view.. comfortable clean!! "
United States
Hector
The price is AU$112
4 May - 5 May
Skyline Ecoliving

Olive Country Living - 311

Olive Country Living - 311
2.0 star property
Envigado
The price is AU$325
13 May - 14 May
Olive Country Living - 311

Apto muy bien ubicado- Home ARIS 401

Apto muy bien ubicado- Home ARIS 401
3.5 star property
La Candelaria
10.0 out of 10, Exceptional, (1 review)
"O apartamento é muito bem localizado e organizado, Dona Iolanda muito prestativa e atenciosa."
Brazil
Ricardo
The price is AU$73
1 May - 2 May
Apto muy bien ubicado- Home ARIS 401

Casa Museo by HOUSY

Casa Museo by HOUSY
3.5 star property
Laureles
10.0 out of 10, Exceptional, (1 review)
"The water was very hot which was nice. I ordered a room with a jacuzzi. But when i got there i received a basic room. After complaining they gave me the room with the jacuzzi. However the hotel price was reasonable so its really nothing to complain about. The rooms are very nice and the esthetics are beautiful. The pool are is very beautiful as well. "
United States
James
The price is AU$86
3 May - 4 May
Casa Museo by HOUSY

Frontera by Roots Rentals

Frontera by Roots Rentals
2.0 star property
El Poblado
9.2 out of 10, Wonderful, (22 reviews)
"Great experience overall! Would stay here again. "
United States
Matthew
The price is AU$61
3 May - 4 May
Frontera by Roots Rentals

zenia

zenia
3.0 star property
Laureles
9.4 out of 10, Exceptional, (47 reviews)
"It was a Great Experience😊"
United States
Peter
The price is AU$42
3 May - 4 May
zenia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Santa Cruz Hotel Reviews

Find out more about Santa Cruz

Everything you need to know about Santa Cruz holiday rentals

Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the Santa Cruz holiday rental for you. At Expedia, you can take your pick from private holiday homes, apartments, cottages, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santa Cruz holiday rental for you by simply entering your desired dates. Then check your favourite filters to narrow down your search. 

Santa Cruz holiday rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santa Cruz. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depend on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Santa Cruz holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Santa Cruz holiday rentals we have selected for you start as low as AU$42 per night. Entering your travel dates in the search wizard might find you even better deals!

How to find incredible deals on Santa Cruz rentals

At Expedia, we put the best Santa Cruz holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top Santa Cruz rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santa Cruz holiday.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santa Cruz. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. 

Frequently asked questions

Can I find a holiday rental in Santa Cruz?

Yes, there are holiday rentals close to the most popular sights in Santa Cruz, or you can select a more secluded option if you're looking for a relaxing stay.

What are some of the best holiday rentals that Santa Cruz has to offer?

Luxury Home In Las Lomas: This holiday home rental outside Santa Cruz is equipped with an outdoor pool, air conditioning and free WiFi to help you feel comfortable during your stay. It has 6 bedrooms, as well as a kitchen with a full-sized fridge, a microwave and kitchenware, so that you can cook with friends or family.

What’s there to see and do in Santa Cruz?

While exploring the area, visit family-friendly sights like Pueblito Paisa, or get outside and enjoy nature at Medellin Botanical Garden. In the wider area, you’ll find University of Antioquia and Arvi Park.

What’s a holiday rental in Santa Cruz like?

Holiday rentals are private properties where you can stay for a few weeks, or just a few days, in Santa Cruz. Holiday rentals offer extras like WiFi and washers and dryers so you'll feel right at home. If you're concerned about a clean environment, holiday rentals can offer a sense of safety away from public hotel lifts and lobbies bustling with people while still allowing you the enjoyment of travel. You'll also find more space in a holiday rental than in a standard hotel, which is another reason why a holiday rental is a popular option for families.