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25 Dec - 26 Dec
Tomorrow
26 Dec - 27 Dec
This weekend
26 Dec - 28 Dec
Next weekend
2 Jan - 4 Jan

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Our top choices for Santa Clara hotels

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SAND DIAMOND HOTEL

SAND DIAMOND HOTEL

SAND DIAMOND HOTEL
3.0 star property
Colon
8.6 out of 10, Excellent, (213)
"The Sand Diamond Hotel is a very nice facilities."
United States
Juan
Travelling for leisure and business
The price is AU$195
includes taxes & fees
29 Dec - 30 Dec
SAND DIAMOND HOTEL
Poolside bar
Gamboa Rainforest Reserve

Gamboa Rainforest Reserve

Gamboa Rainforest Reserve
3.5 star property
Colon
7.8 out of 10, Good, (667)
"Staying here with our family, we loved the excursions to see wildlife so close to the resort."
United States
Kevin
Travelling for leisure
The price is AU$202
includes taxes & fees
2 Jan - 3 Jan 2026
Gamboa Rainforest Reserve
Front of property
Panama House Bed & Breakfast

Panama House Bed & Breakfast

Panama House Bed & Breakfast
2.5 star property
Bella Vista
9.0 out of 10, Wonderful, (185)
"The beds were wonderfully comfortable"
United States
Egypt
The price is AU$68
includes taxes & fees
3 Jan - 4 Jan 2026
Panama House Bed & Breakfast
3 outdoor pools, pool umbrellas, pool loungers
The Westin Playa Bonita Panama

The Westin Playa Bonita Panama

The Westin Playa Bonita Panama
5.0 star property
Veracruz
8.0 out of 10, Very good, (1000)
"The Spa was really nice and the gym"
United States
Adriana Angelina
Travelling with family
The price is AU$374
includes taxes & fees
8 Jan - 9 Jan 2026
The Westin Playa Bonita Panama
Ecotours
Hotel Pension Corona

Hotel Pension Corona

Hotel Pension Corona
2.5 star property
Calidonia
7.8 out of 10, Good, (109)
"Great spot for the price "
United States
frank
Hotel Pension Corona
Living area
Magnolia Inn

Magnolia Inn

Magnolia Inn
2.0 star property
Casco Viejo
8.8 out of 10, Excellent, (417)
"The room was clean and well equipment for the price range"
Canada
Lloyd
Travelling with partner
The price is AU$78
includes taxes & fees
28 Dec - 29 Dec
Magnolia Inn
Aerial view
Hotel Latino

Hotel Latino

Hotel Latino
3.0 star property
Calidonia
6.6 out of 10, (220)
"I was given room key attached to a piece of plastic. It was difficult to tell exactly which room number it was. I unlocked what I thought was my room and saw someone laying in bed unaware I opened the door slightly. I closed the door and asked a housekeeper which room I was in. She told me. When I entered my room the overpowering smell of moth balls was present. I found a room elsewhere and left after an hour. Staff was nice, I didn’t feel the need to go complain but I didn’t feel secure since...
United States
Paul Andrew
Hotel Latino
Outdoor pool, open 7:00 AM to 10:30 PM, free pool cabanas
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
4.0 star property
Tocumen
8.6 out of 10, Excellent, (1847)
"The pool is very nice"
United States
karen
Travelling for leisure
The price is AU$205
includes taxes & fees
26 Dec - 27 Dec
Riande Aeropuerto Hotel & Casino
Reception
Residencial & Hotel Palazzo

Residencial & Hotel Palazzo

Residencial & Hotel Palazzo
3.0 star property
Calidonia
7.4 out of 10, Good, (122)
"The bed was actually comfortable."
United States
Darrion
Travelling for leisure
Residencial & Hotel Palazzo
Terrace/patio
Tantalo Hotel

Tantalo Hotel

Tantalo Hotel
3.5 star property
Casco Viejo
8.8 out of 10, Excellent, (275)
"Super fun bar on rooftop with great views of city and restaurant in lobby."
United States
Negar
Travelling for leisure
Tantalo Hotel
Interior detail
Canova

Canova

Canova
3.0 star property
Calidonia
8.2 out of 10, Very good, (131)
"Very close place to everything. Very affordable. "
United States
Alex
The price is AU$47
includes taxes & fees
8 Jan - 9 Jan 2026
Canova
Outdoor pool, pool umbrellas, pool loungers
Holiday Inn Panama Canal by IHG

Holiday Inn Panama Canal by IHG

Holiday Inn Panama Canal by IHG
3.5 star property
Panama City
8.6 out of 10, Excellent, (443)
"Convenient location, great view of the Panama Canal."
United States
Javier
Travelling for leisure
The price is AU$184
includes taxes & fees
26 Dec - 27 Dec
Holiday Inn Panama Canal by IHG
Double Room
Hotel Discovery

Hotel Discovery

Hotel Discovery
2.5 star property
Calidonia
7.4 out of 10, Good, (169)
"Rooms was nice and clean. Transportation was easy area was peaceful. "
United States
Roniald
The price is AU$45
includes taxes & fees
3 Jan - 4 Jan 2026
Hotel Discovery
Exterior
Hotel Plaza Herrera

Hotel Plaza Herrera

Hotel Plaza Herrera
4.0 star property
Casco Viejo
10.0 out of 10, Exceptional, (14)
"Every detail, from the plush bedding to the luxurious marble bathroom, made it feel like a boutique retreat."
United States
Kenneth
Travelling with friends
The price is AU$453
includes taxes & fees
29 Dec - 30 Dec
Hotel Plaza Herrera
Classic Double Room, 1 Double Bed, Non Smoking
Hotel Acapulco

Hotel Acapulco

Hotel Acapulco
3.0 star property
Calidonia
7.6 out of 10, Good, (127)
"Excelente"
United States
Alejandro
The price is AU$51
includes taxes & fees
17 Jan - 18 Jan 2026
Hotel Acapulco
Front of property
Hotel California Panama

Hotel California Panama

Hotel California Panama
3.0 star property
Bella Vista
7.8 out of 10, Good, (85)
"Excellent front desk service"
United States
JOSEPH
The price is AU$63
includes taxes & fees
3 Jan - 4 Jan 2026
Hotel California Panama
Terrace/patio
Hotel Vía España

Hotel Vía España

Hotel Vía España
3.0 star property
Calidonia
6.2 out of 10, (169)
"Nice hotel conveniently placed but lots of traffic noise"
United Kingdom
Peter
Hotel Vía España
Outdoor pool, pool umbrellas, pool loungers
The Westin Panama

The Westin Panama

The Westin Panama
4.0 star property
Costa del Este
9.0 out of 10, Wonderful, (311)
"food nearby was t the best but the hotel itself and staff were fantastic"
United States
Bradley
Travelling with partner
The price is AU$351
includes taxes & fees
10 Jan - 11 Jan 2026
The Westin Panama
Double Room
Hotel Montreal

Hotel Montreal

Hotel Montreal
3.5 star property
Bella Vista
6.0 out of 10, (397)
"Friendly staff alright room"
Canada
Ryan
Hotel Montreal
Restaurant
Hotel Costa Inn

Hotel Costa Inn

Hotel Costa Inn
3.0 star property
Calidonia
7.0 out of 10, Good, (539)
"The good thing about the location is that it is close to Metro."
United States
Ruby
Travelling solo
Hotel Costa Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Santa Clara attractions

Culebra Cut

You can learn about the history of Santa Clara when you stop by Culebra Cut. Visit the casinos and top-notch restaurants in this walkable area.
See properties

Learn more about Santa Clara

Santa Clara awaits: its natural setting, monuments, history and more!

See all hotels in Santa Clara
Adobe

Top Santa Clara Hotel Reviews

Recent Reviews in Santa Clara

Decapolis Hotel Panama City

Decapolis Hotel Panama City

10/10 Excellent
"Good"
Mario 2-night trip
Posted 2 days ago
Decapolis Hotel Panama City

More cheap accommodation in Santa Clara

Panama House Bed & Breakfast

Panama House Bed & Breakfast

Calle 1era El Carmen- Casa # 32 Panama City
The price is AU$68 per night from 3 Jan to 4 Jan
AU$68
3 Jan - 4 Jan 2026
includes taxes & fees
8.8/10 Excellent! (185 reviews)

Frequently asked questions

What's the best place to stay in Santa Clara?
Located 15.8 mi (25.5 km) from the heart of Santa Clara, Hotel Riu Plaza Panama is a top choice for your stay, based on our traveller data. Other good options for your trip to the area are Las Americas Golden Tower Panama and Megapolis Hotel Panamá. See all available top hotels, or vacation rentals in Santa Clara.
What are some of the best holiday rentals that Santa Clara has to offer?
Oasis with pool near panama canal: This holiday home rental outside of Santa Clara offers an outdoor pool, a patio and a BBQ to help you feel perfectly comfortable in your new surroundings. It has 4 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. Make the most of garden in this rental home to help you unwind. See all vacation rentals in Santa Clara.
If I need to cancel my hotel reservation in Santa Clara, will I receive a refund?
Yes, you'll find most hotel bookings are fully refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, you may still be able to cancel and receive a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Clara.
What is staying in Santa Clara like?
Visitors can enjoy all that Santa Clara has to offer, including its monuments. A top sight in the area is Albrook Shopping Mall. There are 1675 hotels and other accommodation options in the surrounding area. Find out more about Santa Clara.
What should I do while I'm visiting Santa Clara?
A favourite place to visit is Culebra Cut. Additionally, you'll find Albrook Shopping Mall in the area. Take a look at what more there is to see and do in Expedia's Santa Clara guide.
What's the weather like in Santa Clara?
The hottest months are usually April and March, with an average temperature of 26°C, while the coldest months are January and February, with an average of 26°C. The rainiest months in Santa Clara are July, August, November and October, with each month seeing an average of 283 mm of rainfall.

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