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Our top choices for Santa Clara hotels

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
4.0 star property
Tocumen
8.6 out of 10, Excellent, (1,861 reviews)
"Very nice staff and confortable stay"
United States
MARIA
The price is AU$196
includes taxes & fees
10 Feb - 11 Feb
Riande Aeropuerto Hotel & Casino

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (4,936 reviews)
" Nice hotel and great location "
United States
Wajdi
The price is AU$207
includes taxes & fees
10 Mar - 11 Mar
Hotel Riu Plaza Panama

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz
9.6 out of 10, Exceptional, (662 reviews)
"As usual the stay was amazing in this hotel"
United States
Jose
The price is AU$422
includes taxes & fees
13 Feb - 14 Feb
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
4.0 star property
San Antonio
8.8 out of 10, Excellent, (1,008 reviews)
"Staff was good rooms clean just a good experience "
United States
Adrian
The price is AU$165
includes taxes & fees
23 Feb - 24 Feb
Courtyard by Marriott Panama Metromall

Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
San Francisco
9.4 out of 10, Exceptional, (2,179 reviews)
"Hotel was very clean, the staff was very helpful and the breakfast was very good!"
United States
Monty
The price is AU$248
includes taxes & fees
1 Mar - 2 Mar
Plaza Paitilla Inn Hotel

Hyatt Regency Panama City

Hyatt Regency Panama City
4.5 star property
Bella Vista
9.8 out of 10, Exceptional, (193 reviews)
"Very clean modern rooms, spacious hotel, delicious breakfast, very friendly staff!"
Canada
Sheldon
The price is AU$258
includes taxes & fees
7 Mar - 8 Mar
Hyatt Regency Panama City

Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
San Francisco
9.6 out of 10, Exceptional, (1,161 reviews)
"Great staff, breakfast and location "
Canada
Corinne
The price is AU$173
includes taxes & fees
25 Feb - 26 Feb
Ramada Plaza by Wyndham Panama Punta Pacifica

Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,004 reviews)
"Good locatiion"
United States
Caren
The price is AU$210
includes taxes & fees
20 Feb - 21 Feb
Sheraton Grand Panama

Arcadia Condo Suites

Arcadia Condo Suites
2.5 star property
Costa del Este
9.2 out of 10, Wonderful, (206 reviews)
"Really loved this place"
United States
Alejandra
The price is AU$196
includes taxes & fees
2 Mar - 3 Mar
Arcadia Condo Suites

Radisson Hotel Panama Canal

Radisson Hotel Panama Canal
4.5 star property
Amador
8.6 out of 10, Excellent, (1,006 reviews)
"Unbeatable location if your visit is all about the Panama Canal. "
United States
Vitaliy
The price is AU$124
includes taxes & fees
21 Feb - 22 Feb
Radisson Hotel Panama Canal

W Panama

W Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,004 reviews)
"Second time staying and it was flawless."
United States
Anthony
The price is AU$287
includes taxes & fees
7 Mar - 8 Mar
W Panama

The Westin Playa Bonita Panama

The Westin Playa Bonita Panama
5.0 star property
Veracruz
8.0 out of 10, Very good, (1,012 reviews)
"Beautiful property and amazing staff"
United States
CARMEN
The price is AU$371
includes taxes & fees
9 Mar - 10 Mar
The Westin Playa Bonita Panama

Riande Urban Hotel

Riande Urban Hotel
3.5 star property
Bella Vista
8.8 out of 10, Excellent, (1,059 reviews)
"Clean spacious room and friendly staff"
United States
Leslie
The price is AU$132
includes taxes & fees
11 Feb - 12 Feb
Riande Urban Hotel

Ramada Panama Centro Via Argentina

Ramada Panama Centro Via Argentina
3.0 star property
Bella Vista
7.4 out of 10, Good, (290 reviews)
"The staff was super friendly "
United States
Anneliase
The price is AU$133
includes taxes & fees
10 Feb - 11 Feb
Ramada Panama Centro Via Argentina

The Executive Hotel

The Executive Hotel
3.5 star property
Bella Vista
9.2 out of 10, Wonderful, (1,030 reviews)
"Breakfast was excellent, Rooms are lovely "
United States
Kera Michele Naomi
The Executive Hotel

JW Marriott Panama

JW Marriott Panama
5.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,006 reviews)
"Beautiful hotel, great service. Breakfast buffet is amazing. "
United States
Tamara
The price is AU$453
includes taxes & fees
7 Mar - 8 Mar
JW Marriott Panama

Decapolis Hotel Panama City

Decapolis Hotel Panama City
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,545 reviews)
"Nice comfortable hotel and very friendly staff."
Canada
norah
The price is AU$178
includes taxes & fees
27 Feb - 28 Feb
Decapolis Hotel Panama City

Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino
4.0 star property
Bella Vista
9.0 out of 10, Wonderful, (695 reviews)
"Great place to stay and friendly staff!"
United States
Leonardo
The price is AU$155
includes taxes & fees
18 Feb - 19 Feb
Waymore Hotel Spa & Casino

Hotel Milan

Hotel Milan
3.0 star property
Bella Vista
9.0 out of 10, Wonderful, (468 reviews)
"Great place for a short stay."
United States
Luis
The price is AU$63
includes taxes & fees
10 Feb - 11 Feb
Hotel Milan

The Beach House

The Beach House
3.0 star property
Amador
8.4 out of 10, Very good, (414 reviews)
"We loved the staff, room & view! "
United States
Jerome
The Beach House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What's the best place to stay in Santa Clara?
Located 15.8 mi (25.5 km) from the heart of Santa Clara, Hotel Riu Plaza Panama is a top choice for your stay, based on our traveller data. Other good options for your trip to the area are Waldorf Astoria Panama and Hotel El Panama by Faranda Grand, a member of Radisson Individuals. See all available top hotels, or vacation rentals in Santa Clara.
What are some of the best holiday rentals that Santa Clara has to offer?
Fully Remodeled Casa AcoModo – 6BR, Pool, Rooftop Jacuzzi & BBQ Discover our completely remodeled home in Casco Viejo, perfect for up to 12 guests. Relax by the pool, enjoy the rooftop jacuzzi and BBQ, and experience modern comfort blended with hi: This holiday home rental outside of Santa Clara is located in the city centre, and has a balcony, a garden and a BBQ to put you at ease in your new surroundings. It has 5 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. Make the most of games in this rental home to help you unwind. See all vacation rentals in Santa Clara.
If I need to cancel my hotel reservation in Santa Clara, will I receive a refund?
Yes, you'll find most hotel bookings are fully refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, you may still be able to cancel and receive a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Clara.
What is staying in Santa Clara like?
Visitors can enjoy all that Santa Clara has to offer, including its monuments. A top sight in the area is Albrook Shopping Mall. There are 1700 hotels and other accommodation options in the surrounding area. Find out more about Santa Clara.
What should I do while I'm visiting Santa Clara?
A favourite place to visit is Culebra Cut. Additionally, you'll find Albrook Shopping Mall in the area. Take a look at what more there is to see and do in Expedia's Santa Clara guide.
What's the weather like in Santa Clara?
The hottest months are usually April and March, with an average temperature of 26°C, while the coldest months are January and February, with an average of 26°C. The rainiest months in Santa Clara are July, August, November and October, with each month seeing an average of 283 mm of rainfall.