Downtown South San Francisco Travel Guide
Tourist Guide
Visit Downtown South San Francisco
Activities
California Academy of Sciences Daytime Admission
Go City: San Francisco All-Inclusive Pass with 30+ Attractions
San Francisco: One day Yosemite and Giant Sequoias Tour
San Francisco, Muir Woods, Sausalito and Optional Alcatraz Tour
Muir Woods and Sausalito 1/2 Day Tour (Small Group)
Our pick of the best Downtown South San Francisco Hotel Deals
La Quinta Inn & Suites by Wyndham San Francisco Airport N
"Very convenient"
Reviewed on 1 July 2026
Hotel Riu Plaza Fisherman's Wharf
"This hotel is located in a very central safe place in Fisherman's Wharf where you can walk to just about anything. Breakfast buffet was extraordinary. Warm outdoor pool and spacious rooms. Would highly recommend!"
Reviewed on 2 July 2026
Handlery Union Square Hotel
"I'm surprised at how many positive reviews this hotel has. We may have just been unlucky but weren't happy with our stay. Poor encounter with the valet - the man we were dealing with was super rude. Also, $67/night to park is absurd. I would rather just park my car and pay a more reasonable amount ..."
Reviewed on 2 July 2026
Hyatt Regency San Francisco
"I had a great stay here, the room was clean & the staff was very friendly and open to answering any questions I had!"
Reviewed on 2 July 2026
Hotel Zoe Fisherman's Wharf
"Property was bright spot of an area that is in decline. FANTASTIC service from the front desk and friendly staff. Very comfy room."
Reviewed on 3 July 2026
Holiday Inn Golden Gateway by IHG
"Clean and very friendly environment. Close to lots of places to explore with transportation readily available."
Reviewed on 2 July 2026
Our guide on where to stay in Downtown South San Francisco
Fisherman's Wharf
Travellers love Fisherman's Wharf for its popular shops, and you can see more of San Francisco by jumping on the metro at Jones St and Beach St Stop or Jefferson St & Taylor St Stop. You might spend time checking out top sights like Pier 39 and San Francisco Bay.
Union Square
Known for its charming cafes and popular shops, there's plenty to explore in Union Square. Check out top attractions like Westin St Francis Hotel Glass Elevators and Union Square, and jump on the metro at Powell St & Geary Blvd Stop or Powell St & Post St Stop to see more of the city.
Downtown San Francisco
Known for its fascinating museums, popular shops and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and Chase Center are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.
South of Market
Gourmet restaurants great entertainment and top sights from Oracle Park to San Francisco Bay – discover South of Market, a destination also famous for its shopping.
Nob Hill
Gourmet restaurants Chinatown and top sights from SF Masonic Auditorium to Cable Car Museum – discover Nob Hill, a destination also famous for its shopping.
