Medical Center District Travel Guide
Tourist Guide
Visit Medical Center District
Stay near popular Medical Center District attractions
Activities
San Antonio: Six Flags Fiesta Texas Admission Ticket
AU$71
per adult
San Antonio: Discovery Tour at Natural Bridge Caverns
AU$55
per adult
98% of travellers recommend
San Antonio: Fredericksburg Wineries Day Trip with Tastings
AU$260
per adult
100% of travellers recommend
The Undead: Zombie Apocalypse Escape Room at Extreme Escape
AU$46
per adult
The Buckhorn Saloon & Museum and Texas Ranger Museum Admission
AU$33
per adult
84% of travellers recommend
Our pick of the best Medical Center District Hotel Deals
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
4431 Horizon Hill Blvd San Antonio TX
The price is AU$150 per night from 27 July to 28 July
AU$150
27 July - 28 July
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the helpful staff ...
Courtyard by Marriott Medical Center San Antonio
8585 Marriott Dr San Antonio TX
The price is AU$151 per night from 8 Aug to 9 Aug
AU$151
8 Aug - 9 Aug
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,002 reviews)
"Very clean facility, pool was in business a d it was nice, peaceful and quiet."
Reviewed on 24 July 2026
Drury Inn & Suites San Antonio Northwest Medical Center
9806 Interstate Hwy 10 W San Antonio TX
The price is AU$158 per night from 5 Aug to 6 Aug
AU$158
5 Aug - 6 Aug
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...
San Antonio Marriott Northwest Medical Center
3233 NW Loop 410 San Antonio TX
The price is AU$187 per night from 7 Aug to 8 Aug
AU$187
7 Aug - 8 Aug
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy room service, a 24-hour fitness centre and Wi-Fi (surcharge). Our guests praise the helpful staff ...
8.6/10 Excellent! (1,131 reviews)
"Great hotel. Room was very clean!"
Reviewed on 25 July 2026
Drury Plaza Hotel San Antonio Riverwalk
105 S Saint Marys Street San Antonio TX
The price is AU$251 per night from 8 Aug to 9 Aug
AU$251
8 Aug - 9 Aug
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and 2 hot tubs. Our guests praise the breakfast and the pool in their reviews. ...
9.4/10 Exceptional! (4,951 reviews)
"The staff and the amenities were great. The room I stayed in was good."
Reviewed on 25 July 2026
La Quinta Inn & Suites by Wyndham San Antonio Riverwalk
303 Blum Street San Antonio TX
The price is AU$157 per night from 3 Aug to 4 Aug
AU$157
3 Aug - 4 Aug
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, a fitness centre and parking (surcharge). Our guests praise the breakfast and the ...
8/10 Very good! (4,002 reviews)
"The rooms are small but comfortable enough for a short stay. The bed sheets had a few stains, which made me question whether they had been cleaned well or were just old. The coffee maker was dusty and dirty, so we didn't use it. I also recommend bringing your own soap because the small bar they provide ..."
Reviewed on 25 July 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Our guide on where to stay in Medical Center District
Find the best Medical Center District areas for the activities you enjoy most.
Downtown San Antonio
A scenic riverfront great entertainment and top sights from Alamo to Alamodome – discover Downtown San Antonio, a destination also famous for its historic sites.
Far West Side
While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.
Photo by Sarah C.
Open Photo by Sarah C.
Uptown
If you're spending some time in Uptown, San Antonio Zoo and Aquarium and Marion Koogler McNay Art Museum are top sights worth seeing.
La Cantera District
If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.
Midtown
Unique features of Midtown include the river views and bars. Make a stop by San Antonio Zoo and Aquarium or The DoSeum while you're exploring the area.
