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Medical Center District Hotels, San Antonio

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Our top choices for Medical Center District hotels

1. Drury Inn & Suites San Antonio Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center
3.0 star property
Medical Center District
9.2 out of 10, Wonderful, (1,540 reviews)
"Nice overnight stay."
United States
Sharon
The price is AU$156
includes taxes & fees
23 Nov - 24 Nov
Drury Inn & Suites San Antonio Northwest Medical Center

2. Fairfield Inn & Suites by Marriott San Antonio Medical Center

Fairfield Inn & Suites by Marriott San Antonio Medical Center
3.0 star property
Medical Center District
9.0 out of 10, Wonderful, (1,116 reviews)
"The breakfast was good and staff was very helpful."
United States
Tina
The price is AU$160
includes taxes & fees
15 Nov - 16 Nov
Fairfield Inn & Suites by Marriott San Antonio Medical Center

3. La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
3.0 star property
Medical Center District
8.4 out of 10, Very good, (3,780 reviews)
"Great place to stay"
United States
Gilbert
The price is AU$154
includes taxes & fees
15 Nov - 16 Nov
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

4. San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center
3.5 star property
Medical Center District
8.6 out of 10, Excellent, (1,203 reviews)
"Room was clean, very friendly staff"
Canada
Hsiao Tung
The price is AU$150
includes taxes & fees
12 Dec - 13 Dec
San Antonio Marriott Northwest Medical Center

5. Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio
3.0 star property
Medical Center District
8.8 out of 10, Excellent, (1,001 reviews)
"Great property, nice rooms"
United States
Francisca
The price is AU$155
includes taxes & fees
27 Nov - 28 Nov
Courtyard by Marriott Medical Center San Antonio

6. Park Inn by Radisson, Medical Center

Park Inn by Radisson, Medical Center
2.0 star property
Medical Center District
7.4 out of 10, Good, (1,000 reviews)
"Went with my partner, away from the bustle but still close to everything. Great little place."
United States
Jaime
The price is AU$106
includes taxes & fees
3 Dec - 4 Dec
Park Inn by Radisson, Medical Center

7. Studio 6 San Antonio, Tx - Northwest Medical Center

Studio 6 San Antonio, Tx - Northwest Medical Center
2.0 star property
Medical Center District
7.4 out of 10, Good, (407 reviews)
"It was clean and cheap. I’d stay again but the mattress was old and you could hear and feel the springs sheets and room were clean."
United States
seth
The price is AU$87
includes taxes & fees
13 Nov - 14 Nov
Studio 6 San Antonio, Tx - Northwest Medical Center

8. Atria Inn & Suites

Atria Inn & Suites
2.0 star property
Medical Center District
7.4 out of 10, Good, (321 reviews)
"It’s. Nice place to stay, it’s big and comfortable."
United States
Jose Rolando
The price is AU$87
includes taxes & fees
15 Nov - 16 Nov
Atria Inn & Suites

9. Motel 6 San Antonio, TX - Northwest Medical Center

Motel 6 San Antonio, TX - Northwest Medical Center
2.0 star property
Medical Center District
6.0 out of 10, (1,005 reviews)
"Inexpensive. Above expectations. Quiet, cool, staff friendly."
United States
robert
The price is AU$86
includes taxes & fees
13 Nov - 14 Nov
Motel 6 San Antonio, TX - Northwest Medical Center

10. Studio 6 Extended Stay - San Antonio, TX - Medical Center

Studio 6 Extended Stay - San Antonio, TX - Medical Center
2.0 star property
Medical Center District
6.8 out of 10, (1,003 reviews)
"Good for a short stay traveling through the SA area."
United States
Jerron
The price is AU$90
includes taxes & fees
16 Nov - 17 Nov
Studio 6 Extended Stay - San Antonio, TX - Medical Center

11. OYO Inn & Suites Medical Center San Antonio

OYO Inn & Suites Medical Center San Antonio
2.0 star property
Medical Center District
7.4 out of 10, Good, (251 reviews)
"great place to stay close to the hospital. Would stay there again"
United States
Melanie
The price is AU$105
includes taxes & fees
25 Nov - 26 Nov
OYO Inn & Suites Medical Center San Antonio

12. Flex Studios

Flex Studios
2.5 star property
Medical Center District
6.2 out of 10, (580 reviews)
"Everything was just fine. 😁"
United States
Jennifer
The price is AU$76
includes taxes & fees
16 Nov - 17 Nov
Flex Studios

13. Hyatt Place San Antonio-Northwest/Medical Center

Hyatt Place San Antonio-Northwest/Medical Center
3.0 star property
3.7 km from Medical Center District
8.4 out of 10, Very good, (1,087 reviews)
"Loved the room and how clean the property was. Would stay here again."
United States
Muri
The price is AU$172
includes taxes & fees
16 Nov - 17 Nov
Hyatt Place San Antonio-Northwest/Medical Center

14. Best Western Medical Center North Inn & Suites Near Six Flags

Best Western Medical Center North Inn & Suites Near Six Flags
2.5 star property
Northwest Side, 5.2 km from Medical Center District
8.2 out of 10, Very good, (1,615 reviews)
"Good budget business hotel."
United States
Vijay
The price is AU$113
includes taxes & fees
15 Nov - 16 Nov
Best Western Medical Center North Inn & Suites Near Six Flags

15. Drury Inn & Suites Near La Cantera Parkway

Drury Inn & Suites Near La Cantera Parkway
3.0 star property
La Cantera District, 9.5 km from Medical Center District
9.4 out of 10, Exceptional, (2,060 reviews)
"Excellent stay, great location, clean"
United States
Dominique
The price is AU$163
includes taxes & fees
23 Nov - 24 Nov
Drury Inn & Suites Near La Cantera Parkway

16. Hampton Inn & Suites San Antonio Northwest/Medical Center

Hampton Inn & Suites San Antonio Northwest/Medical Center
2.5 star property
Northwest Side, 4.7 km from Medical Center District
8.6 out of 10, Excellent, (1,008 reviews)
"Great place clean room good breakfast nice staff"
United States
Ioana
The price is AU$151
includes taxes & fees
23 Nov - 24 Nov
Hampton Inn & Suites San Antonio Northwest/Medical Center

17. La Quinta Inn & Suites by Wyndham San Antonio Northwest

La Quinta Inn & Suites by Wyndham San Antonio Northwest
3.0 star property
Far West Side, 10.4 km from Medical Center District
8.8 out of 10, Excellent, (1,001 reviews)
"Bed was comfortable and the room was very spacious."
United States
Elysabeth
The price is AU$136
includes taxes & fees
15 Nov - 16 Nov
La Quinta Inn & Suites by Wyndham San Antonio Northwest

18. Hyatt Vacation Club at Wild Oak Ranch, San Antonio

Hyatt Vacation Club at Wild Oak Ranch, San Antonio
3.5 star property
Far West Side, 11.3 km from Medical Center District
9.0 out of 10, Wonderful, (2,074 reviews)
"Excellent vacation location."
United States
Eric
The price is AU$196
includes taxes & fees
1 Dec - 2 Dec
Hyatt Vacation Club at Wild Oak Ranch, San Antonio

19. Courtyard by Marriott San Antonio Lackland

Courtyard by Marriott San Antonio Lackland
3.0 star property
6.5 km from Medical Center District
8.2 out of 10, Very good, (1,001 reviews)
"Clean room, very roomy, we loved our stay"
United States
Jolynn
The price is AU$141
includes taxes & fees
15 Nov - 16 Nov
Courtyard by Marriott San Antonio Lackland

20. Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

Heritage Inn & Suites San Antonio Airport, Trademark Wyndham
2.5 star property
Uptown Central, 9.3 km from Medical Center District
9.0 out of 10, Wonderful, (2,408 reviews)
"Clean room, breakfast was great and filling. Hotel is super comfortable and easy city accesible."
United States
David
The price is AU$137
includes taxes & fees
15 Nov - 16 Nov
Heritage Inn & Suites San Antonio Airport, Trademark Wyndham
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Medical Center District

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A spacious lobby with multiple seating areas, a central coffee table, and a view of the upper floors.
Drury Inn & Suites San Antonio Northwest Medical Center
3.0 star property
9.2
Wonderful
1,540 reviews
View
A modern living room with a fireplace, a flat-screen TV, and a stone accent wall.
Fairfield Inn & Suites by Marriott San Antonio Medical Center
3.0 star property
9.0
Wonderful
1,116 reviews
View
A modern bar area with wooden bar counters, black bar stools, and pendant lighting.
Courtyard by Marriott Medical Center San Antonio
3.0 star property
8.8
Excellent
1,001 reviews
View
A spacious lobby with a central staircase, seating area, and large windows.
San Antonio Marriott Northwest Medical Center
3.5 star property
8.6
Excellent
1,203 reviews
View
A hotel dining area with multiple tables and chairs, a counter with a coffee machine, and a view of the outside through large windows.
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
3.0 star property
8.4
Very good
3,780 reviews
View

Our guide on where to stay in Medical Center District

Find the best Medical Center District areas for the activities you enjoy most.

Downtown San Antonio

Explore the network of pedestrian paths that follows the beautiful San Antonio River to discover restaurants and bars, gift shops, galleries and museums.

Uptown Central

If you're spending some time in Uptown Central, Marion Koogler McNay Art Museum and Alamo Quarry Market are top sights worth seeing.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

Northwest Side

If you're spending some time in Northwest Side, Huebner Oaks and Crystal Ice Palace are top sights worth seeing.

Stone Oak

Stone Oak is known for its abundant dining options, and you can plan a trip to Shops at Hardy Oak and Alta Vista at Stone Oak while you're in town.

Top Medical Center District Hotel Reviews

Recent Reviews in Medical Center District

Frequently asked questions

What are the best hotels in Medical Center District that travellers recommend?
Two of the best hotels in Medical Centre District that receive consistently high recommendations from travellers are the San Antonio Marriott Northwest Medical Center and the SpringHill Suites by Marriott San Antonio Medical Center/NW.

The San Antonio Marriott Northwest Medical Center, with an 8.6 rating, offers a luxurious experience with amenities such as champagne service, designer toiletries, and premium bedding. Guests frequently praise its comfortable and clean rooms, exceptional staff, and superb location. It is conveniently located near the First Unitarian Universalist Church and Dellview Park.

Another highly recommended option is the SpringHill Suites by Marriott San Antonio Medical Center/NW, which has an 8.8 rating. This hotel features spacious and clean suites with premium bedding, and guests appreciate the complimentary continental breakfast. It is well-located, with the Wonderland of the Americas Mall a short distance away.
What are the best family hotels in Medical Center District?
For families travelling to the Medical Centre District, the Drury Inn & Suites San Antonio Northwest Medical Center and the Courtyard by Marriott Medical Center San Antonio are excellent choices.

The Drury Inn & Suites San Antonio Northwest Medical Center, with an impressive 9.2 rating, offers comfortable, clean rooms and free buffet breakfast, which guests describe as good. The staff are frequently praised for being friendly and great.

Another highly-rated option is the Courtyard by Marriott Medical Center San Antonio, which has an 8.8 rating. This hotel provides comfortable, clean rooms and guests appreciate the convenient, free self-parking. The staff are consistently described as friendly, and the hotel's location is reported as quiet and good.
What hotels in Medical Center District offer free breakfast?
Several hotels in the Medical Centre District offer complimentary breakfast, including the Drury Inn & Suites San Antonio Northwest Medical Center, Fairfield Inn & Suites by Marriott San Antonio Medical Center, SpringHill Suites by Marriott San Antonio Medical Center/NW, and La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW.

The Drury Inn & Suites San Antonio Northwest Medical Center, with an excellent 9.2 rating, provides free breakfast, including a buffet, and free Wi-Fi. Guests frequently praise the friendly staff, comfortable rooms, and the excellent location, with The San Antonio Art Institute just 0.3 km away.

Another great option is the Fairfield Inn & Suites by Marriott San Antonio Medical Center, rated 9.0. This hotel offers free breakfast, a buffet breakfast, and free Wi-Fi. Reviewers often highlight the friendly staff, comfortable and clean rooms, and the excellent breakfast provided.

The SpringHill Suites by Marriott San Antonio Medical Center/NW, with an 8.8 rating, also offers free breakfast, including continental and to-go options, along with free Wi-Fi. It is conveniently located near First Unitarian Universalist Church (0.8 km) and Wonderland of the Americas Mall (0.3 km). Guests appreciate the spacious rooms and good variety at breakfast.

Lastly, the La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW, rated 8.6, provides free breakfast and a buffet breakfast. Guests often mention the friendly staff and the great breakfast and location.
What are the top pet-friendly hotels in Medical Center District?
In the Medical Centre District, two highly-rated pet-friendly hotels are the San Antonio Marriott Northwest Medical Center and the Drury Inn & Suites San Antonio Northwest Medical Center.

The San Antonio Marriott Northwest Medical Center, with an 8.6 rating, welcomes dogs and provides a dedicated dog exercise area, making it very convenient for pet owners. Guests frequently comment on the comfortable and clean rooms, the exceptional and friendly staff, and its superb location. It is also just 0.6 km from the First Unitarian Universalist Church.

Another excellent option is the Drury Inn & Suites San Antonio Northwest Medical Center, boasting an impressive 9.2 rating. This hotel accommodates both dogs and cats, and offers complimentary breakfast, including a free buffet. Guests consistently praise the friendly and great staff, the comfortable and clean rooms, and the excellent location.
What are the best budget hotels in Medical Center District?
For excellent budget-friendly hotels in the Medical Centre District, consider the Drury Inn & Suites San Antonio Northwest Medical Center, SpringHill Suites by Marriott San Antonio Medical Center/NW, and Fairfield Inn & Suites by Marriott San Antonio Medical Center.

The Drury Inn & Suites San Antonio Northwest Medical Center, with an impressive 9.2 rating, offers complimentary buffet breakfast and free Wi-Fi, along with free self-parking. Guests frequently praise the friendly and great staff, comfortable and clean rooms, and excellent location. It is also conveniently located just 0.3 km from The San Antonio Art Institute.

Another highly-rated option is the SpringHill Suites by Marriott San Antonio Medical Center/NW, which has an 8.8 rating. This hotel provides free breakfast, free Wi-Fi, and free self-parking. Guests highlight the spacious and clean rooms, friendly and helpful staff, and the good variety of breakfast options. It is located 0.3 km from Wonderland of the Americas Mall.

The Fairfield Inn & Suites by Marriott San Antonio Medical Center, with a 9.0 rating, is another fantastic choice. It offers complimentary buffet breakfast, free Wi-Fi, and free self-parking. Travellers consistently praise the friendly and great staff, comfortable and clean rooms, and excellent breakfast.
What are the most romantic hotels in Medical Center District for couples?
For a romantic hotel in the Medical Centre District that is well-suited for couples, consider the San Antonio Marriott Northwest Medical Center.

The San Antonio Marriott Northwest Medical Center, with an 8.6 rating, is an excellent choice. Guests frequently comment on the comfortable and clean rooms, as well as the exceptional and friendly staff. Many rooms offer the added benefit of a balcony, superb for enjoying quiet moments together. The hotel also features an outdoor pool with sun loungers and umbrellas, providing a relaxing setting. It is conveniently located near the Wonderland of the Americas Mall and the Oak Hills Country Club.
What are the best hotels in Medical Center District near Cinemark San Antonio 16?
For a highly-rated hotel in the Medical Centre District near Cinemark San Antonio 16, consider the Fairfield Inn & Suites by Marriott San Antonio Medical Center.

This hotel, with a 9.0 rating, is conveniently located just 1.6 km from Cinemark San Antonio 16. Guests frequently praise the friendly and great staff, as well as the comfortable and clean rooms. It offers a complimentary breakfast, including a buffet, which is often described as excellent. Families will appreciate the availability of free cribs and rollaway extra beds, along with connecting rooms and a sofa bed, providing flexible sleeping arrangements. A swimming pool is also available for relaxation.
When is the best time to go to Medical Center District?
The best time to go to the Medical Center District is during the spring (March to May) or autumn (September to November) months.

During these periods, the weather is generally pleasant, with mild temperatures and lower humidity compared to the peak summer months. This makes it more comfortable for walking between appointments, exploring the district's green spaces, or enjoying outdoor dining. Spring brings blooming flowers, adding to the district's appeal, while autumn offers cooler, crisp air.

For those visiting for medical appointments, these milder seasons can contribute to a more comfortable and less stressful experience, especially if you're spending time outdoors or commuting between facilities.
Can I cancel my hotel reservation on Expedia?
Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline − this is often within 24 to 48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our 'Fully refundable property' filter during your search to find the right Medical Center District hotel for you.
How can I save on a hotel booking in Medical Center District with Expedia?
One Key™—Expedia's free travel rewards program—gives you instant access to discounts with Member Prices on Medical Center District hotels. Plus, you'll earn OneKeyCash™* on eligible bookings to use on future trips. Booking an Expedia hotel and flight package is another great way to save, where bundling can result in significant savings. *Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
How much is the nightly rate for a hotel in Medical Center District?
Hotel prices in Medical Center District often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates and sort search results by 'Price: low to high' for our cheapest rates.

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