Medical Center District Holidays from AU$3,639

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Your Medical Centre District Holiday

Experience all the wonderful things this neighbourhood has to offer with a tailor-made Medical Centre District holiday package. However you picture yourself spending your days here, you'll find countless opportunities for fun, adventure and relaxation. Your trip to Medical Centre District wouldn't be complete without a visit to major attractions nearby such as University of Texas Health and Science Centre at San Antonio, Huebner Oaks and Wonderland of the Americas Mall. Expedia can help you turn your ideal Medical Centre District holiday into reality, whatever your budget or travel plans.

Top Holiday Package Deals in Medical Center District

Price found within the past 48 hours. Click for updated prices.
Menger Hotel

Menger Hotel

3.5 out of 5
Downtown San Antonio
Price was AU$4,149, price is now AU$3,639 per person
AU$3,639
per person
2 Apr - 9 Apr
found 1 day ago
Return flight included
Brisbane (BNE) to San Antonio (SAT)
9/10 Wonderful! (3,521 reviews)
Our stay was awesome!

Reviewed on 1 Mar 2026

The St. Anthony, A Luxury Collection Hotel, San Antonio

The St. Anthony, A Luxury Collection Hotel, San Antonio

4.5 out of 5
Downtown San Antonio
Price was AU$4,702, price is now AU$3,908 per person
AU$3,908
per person
2 Apr - 9 Apr
found 1 day ago
Return flight included
Brisbane (BNE) to San Antonio (SAT)
8.8/10 Excellent! (1,000 reviews)
Lobby was absolutely beautiful!

Reviewed on 23 Feb 2026

Hotel Contessa

Hotel Contessa

4 out of 5
Downtown San Antonio
Price was AU$4,399, price is now AU$3,799 per person
AU$3,799
per person
2 Apr - 9 Apr
found 1 day ago
Return flight included
Brisbane (BNE) to San Antonio (SAT)
9/10 Wonderful! (3,372 reviews)
Everything was great .

Reviewed on 3 Mar 2026

The Westin Riverwalk, San Antonio

The Westin Riverwalk, San Antonio

4 out of 5
Downtown San Antonio
Price was AU$4,643, price is now AU$4,037 per person
AU$4,037
per person
2 Apr - 9 Apr
found 1 day ago
Return flight included
Brisbane (BNE) to San Antonio (SAT)
8.8/10 Excellent! (1,397 reviews)
The staff was absolutely wonderful, the riverwalk setting with the holiday lights glistening off the balcony patio doors was magical. Pay the extra to have a room on the riverwalk side with the outdoor patio, it’s was well worth the enjoyment, especially during the holiday season. The hotel and rooms were fabulous and the location was easy to walk to many places. We had a wonderful trip!

Reviewed on 2 Mar 2026

Hyatt Regency Hill Country Resort and Villas

Hyatt Regency Hill Country Resort and Villas

4 out of 5
Far West Side
Price was AU$5,602, price is now AU$4,950 per person
AU$4,950
per person
2 Apr - 9 Apr
found 1 day ago
Return flight included
Brisbane (BNE) to San Antonio (SAT)
8.8/10 Excellent! (1,001 reviews)
Felt like a vacation. It was perfect

Reviewed on 11 Feb 2026

Our guide on where to stay in Medical Center District

Find the best Medical Center District areas and neighborhoods for the activities you enjoy most. Learn more about Medical Center District
Downtown - Riverwalk featuring heritage architecture, boating and a bridge

Downtown San Antonio

4 out of top 10 points of interest in this area
4.5/5(29 area reviews)

Explore the network of pedestrian paths that follows the beautiful San Antonio River to discover restaurants and bars, gift shops, galleries and museums.

Find hotels in Downtown San Antonio

Our pick of the best Medical Center District Hotel Deals

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

3 out of 5
4431 Horizon Hill Blvd San Antonio TX
Fully refundableReserve now, pay when you stay
The price is AU$148 per night from 4 Mar to 5 Mar
AU$148
4 Mar - 5 Mar
includes taxes & fees
8.4/10 Very Good! (3,214 reviews)
Comfortable. New charge for $10 for parking that I was not aware of it.

Reviewed on 2 Mar 2026

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center

3.5 out of 5
3233 NW Loop 410 San Antonio TX
Fully refundableReserve now, pay when you stay
The price is AU$169 per night from 3 Apr to 4 Apr
AU$169
3 Apr - 4 Apr
includes taxes & fees
8.6/10 Excellent! (1,003 reviews)
Everything was great!! Went for my birthday and it was so fun :) wish I had a chance to check out the pool but I was pretty tired 😴

Reviewed on 1 Mar 2026

San Antonio Marriott Northwest Medical Center
Park Inn by Radisson

Park Inn by Radisson

2 out of 5
7500 Louis Pasteur Drive San Antonio TX
Fully refundableReserve now, pay when you stay
The price is AU$105 per night from 22 Mar to 23 Mar
AU$105
22 Mar - 23 Mar
includes taxes & fees
7.2/10 Good! (1,001 reviews)
Nothing out of the ordinary but in a good way.

Reviewed on 28 Feb 2026

Park Inn by Radisson
See all 4,796 properties in Medical Center District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
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beach holidays
Beach Holidays
Beach Holidays

Frequently asked questions

How much does a Medical Centre District holiday package cost?
Starting from just AU$3,639, a holiday package is your passport to low-priced travel. Create your own Medical Centre District adventure by picking from our huge range of airfares, hotels and rental cars.
How do I get a cheap travel package to Medical Centre District?
It's as simple as bundling. Hotels, rental cars and flights — combine whatever you need into a Medical Centre District holiday package and save. Score even better deals when you include extras such as activities or tours to your booking. But that's not the only good part. You have the freedom to customize your holiday your own way. We offer over 550 airlines and 1 000 000 properties throughout the world, so that everyone has a chance to travel and fulfil those holiday dreams.
Where should I stay in Medical Centre District?
Make a reservation just around the corner from Six Flags Fiesta Texas, one of this area's most well-known attractions. It's the ideal spot for serious sightseers.
What are the top hotels in Medical Centre District?
Amazing, Contemporary, Beautiful and Fairfield Inn & Suites by Marriott San Antonio Medical Centre are two of the most well-known hotels in Medical Centre District. Why not take a look at the amenities and rates at each and then make up your mind?
How far in advance should I book my Medical Centre District holiday?
It all depends on the airline, but it's usually possible to look up international fares on Expedia up to 12 months in advance. While it's generally recommended to book ahead of time, lucky customers will sometimes nab a cheaper ticket just weeks before the date of departure.
What does an Expedia Medical Centre District travel package include?
Flights, car rentals and hotels — we connect you to the very best deals. All you'll have to do is figure out your ideal combination. Once you've made your booking, you can add on the fun stuff like activities and sightseeing tours. Our travel packages make it easy to customize an exciting Medical Centre District holiday.
What should I know before booking a Medical Centre District travel package?
You'll save plenty with an Expedia travel package. Combine your airfares, rental cars and hotels and land fantastic discounts. You're not limited to hotels, however. Book with us and select from island resorts, city apartments and just about everything in between!
Can I choose my airline with a Medical Centre District Expedia holiday package?
Yes, you're in charge. We have access to over 550 partner airlines globally, so you can tailor your Medical Centre District trip according to your budget and travel needs.
If I'm not able to travel, can I cancel my Medical Centre District holiday package?
Whether it's your hotel or flight, you can cancel or change it. Booked your Medical Centre District holiday package in the last 24 hours? You may be able to make any changes for free. For bookings made more than 24 hours ago, you may be charged a fee by your airline, hotel or car rental company. For more information, head to our Customer Service Portal. We're here to help you every step of the way.

Discover the most popular places to visit in Medical Center District

CHRISTUS Santa Rosa Hospital - Medical Center

If CHRISTUS Santa Rosa Hospital - Medical Center is what brings you to town, hopefully you'll have a chance to explore more of San Antonio.

CHRISTUS Santa Rosa Hospital - Medical Center

Activities

San Antonio Zoo Any Day Ticket including ZooLights

San Antonio Zoo Any Day Ticket

AU$42
per adult
96% of travellers recommend
San Antonio Zoo Any Day Ticket
SEA LIFE San Antonio

SEA LIFE San Antonio

AU$37
per adult
78% of travellers recommend
SEA LIFE San Antonio
Go City: San Antonio Explorer Pass - Choose 2 to 5 Attractions

Go City: San Antonio Explorer Pass - Choose 2 to 5 Attractions

AU$147
per adult
80% of travellers recommend
Go City: San Antonio Explorer Pass - Choose 2 to 5 Attractions
See all activities in San Antonio
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.