Medical Center District Travel Guide

Tourist Guide

Photo by Linda Cronan

Popular places to visit

Activities


Our pick of the best Medical Center District Hotel Deals

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

3 out of 5
4431 Horizon Hill Blvd, San Antonio, TX
The price is AU$161 per night from 19 Oct to 20 Oct
AU$161
19 Oct - 20 Oct
includes taxes & fees
Stay at this 3-star business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (3,012 reviews)
"Only there for a short time, left before breakfast"

Reviewed on 13 Oct 2025

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center

3.5 out of 5
3233 NW Loop 410, San Antonio, TX
The price is AU$162 per night from 19 Oct to 20 Oct
AU$162
19 Oct - 20 Oct
includes taxes & fees
Stay at this 3.5-star business-friendly hotel in San Antonio. Enjoy free parking, a free area shuttle, and room service. Our guests praise the helpful staff ...
8.4/10 Very Good! (1,015 reviews)
"Clean room, bathroom, and parking lot"

Reviewed on 11 Oct 2025

San Antonio Marriott Northwest Medical Center
Fairfield Inn & Suites by Marriott San Antonio Medical Center

Fairfield Inn & Suites by Marriott San Antonio Medical Center

2.5 out of 5
7203 Wurzbach Road, San Antonio, TX
The price is AU$158 per night from 26 Oct to 27 Oct
AU$158
26 Oct - 27 Oct
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,011 reviews)
"Wonderful hotel. Always good!!!"

Reviewed on 15 Oct 2025

Fairfield Inn & Suites by Marriott San Antonio Medical Center
Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio

3 out of 5
8585 Marriott Dr, San Antonio, TX
The price is AU$162 per night from 26 Oct to 27 Oct
AU$162
26 Oct - 27 Oct
includes taxes & fees
Stay at this 3-star business-friendly hotel in San Antonio. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.6/10 Excellent! (1,011 reviews)
"We loved the clean room, friendly staff, and nice sitting areas."

Reviewed on 14 Oct 2025

Courtyard by Marriott Medical Center San Antonio
Hotel Valencia Riverwalk

Hotel Valencia Riverwalk

4.5 out of 5
150 E Houston St, San Antonio, TX
Fully refundableReserve now, pay when you stay
The price is AU$273 per night from 31 Oct to 1 Nov
AU$273
31 Oct - 1 Nov
includes taxes & fees
Stay at this 4.5-star luxury hotel in San Antonio. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the bar and the helpful ...
9.4/10 Exceptional! (2,046 reviews)
"Very , very nice hotel it’s my new go to stay now. I love it."

Reviewed on 13 Oct 2025

Hotel Valencia Riverwalk
Sonesta ES Suites San Antonio Downtown Alamo Plaza

Sonesta ES Suites San Antonio Downtown Alamo Plaza

3 out of 5
425 Bonham, San Antonio, TX
The price is AU$159 per night from 16 Nov to 17 Nov
AU$159
16 Nov - 17 Nov
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...
8.2/10 Very Good! (1,786 reviews)
"Wonderful property, so clean and fresh. Only tiny knock is the channel guide on the TV was wrong, but so minor! A GREAT value, just a few minutes walk to Alamo and Riverway!"

Reviewed on 13 Oct 2025

Sonesta ES Suites San Antonio Downtown Alamo Plaza
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Medical Center District

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Northwest Side

If you're spending some time in Northwest Side, Huebner Oaks and Convocation Center are top sights worth seeing.

Northwest Side
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Midtown

Unique features of Midtown include the river views and bars. Make a stop by The DoSeum or San Antonio Zoo and Aquarium while you're exploring the area.

Midtown
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La Cantera District

If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.

La Cantera District
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Tobin Hill

Tobin Hill might not have many top sights, but Alamo and San Antonio Museum of Art are two attractions nearby that you can check out.

Tobin Hill
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Uptown

If you're spending some time in Uptown, Marion Koogler McNay Art Museum and Alamo Quarry Market are top sights worth seeing.

Uptown
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Alamo Heights

You'll enjoy the museums and coffee shops in Alamo Heights. You might want to make time for a stop at San Antonio River or Toilet Seat Museum.

Alamo Heights


Medical Center District Travel Guide

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