Medical Center District Travel Guide

Tourist Guide

River walk in San Antonio
Tourists River Walk San Antonio Texas
Riverboat on the San Antonio River Walk, San Antonio, Texas, United States of America.
River walk in San Antonio
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Popular places to visit

Activities


Our pick of the best Medical Center District Hotel Deals

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

3 out of 5
4431 Horizon Hill Blvd San Antonio TX
The price is AU$146 per night from 20 May to 21 May
AU$146
20 May - 21 May
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (3,356 reviews)
"For the amount of money I spent for a three‑day stay, I expected a much cleaner hotel and better‑maintained amenities. The lobby had a strong vinegar odor that was noticeable every time I walked through. While the staff themselves were wonderful and displayed true southern hospitality, the overall ..."

Reviewed on 19 May 2026

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center

3.5 out of 5
3233 NW Loop 410 San Antonio TX
The price is AU$168 per night from 22 May to 23 May
AU$168
22 May - 23 May
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy a free local area shuttle, room service and a 24-hour fitness centre. Our guests praise the helpful ...
8.6/10 Excellent! (1,063 reviews)
"While the staff was polite and attempted to accommodate us by transferring us to another room, the overall condition of both rooms did not meet the expectations of a deluxe room. The furniture showed visible wear and damage, including torn cushions, chipped finishes, and heavily worn carpet that ..."

Reviewed on 18 May 2026

San Antonio Marriott Northwest Medical Center
Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio

3 out of 5
8585 Marriott Dr San Antonio TX
Fully refundableReserve now, pay when you stay
The price is AU$161 per night from 27 May to 28 May
AU$161
27 May - 28 May
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,000 reviews)
"When I checked for a week and payed CASH IN TOWN FOR A MILITARY EVENT AT LACKLAND AFB DRIVE 25 hours, NO ONE INFORMED ME IF I HAD TO LEAVE EARLY I NEED TO GIVE A NOTICE OR THE HOTEL WOULD RETAIN A FEE OF 129.00. It just not a way to handle playing customers of over 25 years!"

Reviewed on 8 May 2026

Courtyard by Marriott Medical Center San Antonio
Drury Plaza Hotel San Antonio Riverwalk

Drury Plaza Hotel San Antonio Riverwalk

4 out of 5
105 S Saint Marys Street San Antonio TX
The price is AU$224 per night from 2 June to 3 June
AU$224
2 June - 3 June
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and 2 hot tubs. Our guests praise the breakfast and the pool in their reviews. ...
9.4/10 Exceptional! (4,645 reviews)
"Our stay was wonderful! We enjoyed the time we spent there. It was the perfect distance from shops and restaurants. The staff especially Justina was so sweet! We will definitely be back. Pool and hot tubs were great and also the food!"

Reviewed on 19 May 2026

Drury Plaza Hotel San Antonio Riverwalk
Menger Hotel

Menger Hotel

3.5 out of 5
204 Alamo Plaza San Antonio TX
The price is AU$147 per night from 20 May to 21 May
AU$147
20 May - 21 May
includes taxes & fees
Stay at this historic hotel in San Antonio. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the pool and the bar in their reviews. ...
8.8/10 Excellent! (4,016 reviews)
"It was a cool old style hotel, very close to the Alamo and a short walk to the river walk"

Reviewed on 19 May 2026

Menger Hotel
Sonesta ES Suites San Antonio Downtown Alamo Plaza

Sonesta ES Suites San Antonio Downtown Alamo Plaza

3 out of 5
425 Bonham San Antonio TX
The price is AU$196 per night from 20 May to 21 May
AU$196
20 May - 21 May
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and an outdoor pool. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (2,168 reviews)
"Room set up was spacious, cozy and homey. Loved it!"

Reviewed on 18 May 2026

Sonesta ES Suites San Antonio Downtown Alamo Plaza
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Medical Center District

The Alamo in San Antonio, Texas

Northwest Side

If you're spending some time in Northwest Side, Huebner Oaks and Convocation Center are top sights worth seeing.

Northwest Side
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Shearer Hills - Ridgeview

While visiting Shearer Hills - Ridgeview, you might make a stop by sights like North Star Mall and San Pedro Driving Range & Par 3 Course.

Shearer Hills - Ridgeview
River Walk in San Antonio, Texas

Midtown

Unique features of Midtown include the river views and bars. Make a stop by The DoSeum or San Antonio Zoo and Aquarium while you're exploring the area.

Midtown
Texas Six Flags night light,2018

La Cantera District

If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.

La Cantera District
Tobin Hill

Tobin Hill

Tobin Hill might not have many top sights, but San Antonio Museum of Art and McFarlin Tennis Center are two attractions nearby that you can check out.

Tobin Hill
Dallas Skyline Reflection on Trinity River During Sunset, Dallas, Texas.

Uptown

If you're spending some time in Uptown, Marion Koogler McNay Art Museum and Alamo Quarry Market are top sights worth seeing.

Uptown


Medical Center District Travel Guide

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