Medical Center District Travel Guide
Tourist Guide
Visit Medical Center District
Stay near popular Medical Center District attractions
Activities
San Antonio: Six Flags Fiesta Texas Admission Ticket
AU$71
per adult
San Antonio: Discovery Tour at Natural Bridge Caverns
AU$55
per adult
98% of travellers recommend
San Antonio: Fredericksburg Wineries Day Trip with Tastings
AU$260
per adult
100% of travellers recommend
The Undead: Zombie Apocalypse Escape Room at Extreme Escape
AU$46
per adult
The Buckhorn Saloon & Museum and Texas Ranger Museum Admission
AU$33
per adult
84% of travellers recommend
Our pick of the best Medical Center District Hotel Deals
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
4431 Horizon Hill Blvd San Antonio TX
The price is AU$150 per night from 26 July to 27 July
AU$150
26 July - 27 July
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very good! (3,496 reviews)
"Ya conocía este hotel , está un poco dejado, requiere remodelación"
Reviewed on 21 July 2026
Courtyard by Marriott Medical Center San Antonio
8585 Marriott Dr San Antonio TX
The price is AU$150 per night from 7 Aug to 8 Aug
AU$150
7 Aug - 8 Aug
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,000 reviews)
"staff was very friendly. room was clean. great stay!"
Reviewed on 21 July 2026
Drury Inn & Suites San Antonio Northwest Medical Center
9806 Interstate Hwy 10 W San Antonio TX
The price is AU$152 per night from 27 July to 28 July
AU$152
27 July - 28 July
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,398 reviews)
"I would definitely stay here again. The staff were amazing, helpful and friendly. I love that you get breakfast and dinner. The area is conveniently located near the freeway and the hospital."
Reviewed on 20 July 2026
San Antonio Marriott Northwest Medical Center
3233 NW Loop 410 San Antonio TX
The price is AU$168 per night from 22 Aug to 23 Aug
AU$168
22 Aug - 23 Aug
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy room service, a 24-hour fitness centre and Wi-Fi (surcharge). Our guests praise the helpful staff ...
8.6/10 Excellent! (1,126 reviews)
"Great stay at a very comfortable and clean facility"
Reviewed on 20 July 2026
Drury Plaza Hotel San Antonio Riverwalk
105 S Saint Marys Street San Antonio TX
The price is AU$253 per night from 26 July to 27 July
AU$253
26 July - 27 July
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and 2 hot tubs. Our guests praise the breakfast and the pool in their reviews. ...
9.4/10 Exceptional! (4,929 reviews)
"One of the best hotels I’ve stayed in wonderful location and all the add-ons that you get for free just make it 1000% better. We’ll definitely start staying at at these hotels more often"
Reviewed on 22 July 2026
La Quinta Inn & Suites by Wyndham San Antonio Riverwalk
303 Blum Street San Antonio TX
Fully refundableReserve now, pay when you stay
The price is AU$156 per night from 29 July to 30 July
AU$156
29 July - 30 July
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, a fitness centre and parking (surcharge). Our guests praise the breakfast and the ...
8/10 Very good! (3,988 reviews)
"It was ok! No service for 3 days! Breakfast was average. No water in the room."
Reviewed on 21 July 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Check Medical Center District hotel availability
Our guide on where to stay in Medical Center District
Find the best Medical Center District areas for the activities you enjoy most.
Downtown San Antonio
A scenic riverfront great entertainment and top sights from Alamo to Alamodome – discover Downtown San Antonio, a destination also famous for its historic sites.
Far West Side
While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.
Photo by Sarah C.
Open Photo by Sarah C.
Uptown
If you're spending some time in Uptown, San Antonio Zoo and Aquarium and Marion Koogler McNay Art Museum are top sights worth seeing.
La Cantera District
If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.
Midtown
Unique features of Midtown include the river views and bars. Make a stop by San Antonio Zoo and Aquarium or The DoSeum while you're exploring the area.
