Medical Center District Travel Guide
Tourist Guide
Visit Medical Center District
Stay near popular Medical Center District attractions
Activities
San Antonio: Fredericksburg Wineries Day Trip with Tastings
AU$251
per adult
100% of travellers recommend
The Buckhorn Saloon & Museum and Texas Ranger Museum Admission
AU$32
per adult
84% of travellers recommend
The Undead: Zombie Apocalypse Escape Room at Extreme Escape
AU$45
per adult
San Antonio Riverwalk- Indoor Ropes Course & Climbing Experience
AU$49
per adult
Our pick of the best Medical Center District Hotel Deals
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
4431 Horizon Hill Blvd San Antonio TX
The price is AU$151 per night from 22 Oct to 23 Oct
AU$151
22 Oct - 23 Oct
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the helpful staff ...
San Antonio Marriott Northwest Medical Center
3233 NW Loop 410 San Antonio TX
The price is AU$159 per night from 21 Nov to 22 Nov
AU$159
21 Nov - 22 Nov
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy room service, a 24-hour fitness centre and Wi-Fi (surcharge). Our guests praise the helpful staff ...
8.6/10 Excellent! (1,180 reviews)
"Good stay, room was clean, i really have no complaints"
Reviewed on 19 Oct 2026
Drury Inn & Suites San Antonio Northwest Medical Center
9806 Interstate Hwy 10 W San Antonio TX
The price is AU$153 per night from 26 Oct to 27 Oct
AU$153
26 Oct - 27 Oct
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,506 reviews)
"Excellent service and amenities I will stay here again"
Reviewed on 19 Oct 2026
Courtyard by Marriott Medical Center San Antonio
8585 Marriott Dr San Antonio TX
The price is AU$151 per night from 20 Nov to 21 Nov
AU$151
20 Nov - 21 Nov
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
Hotel Valencia Riverwalk
150 E Houston St San Antonio TX
The price is AU$253 per night from 27 Oct to 28 Oct
AU$253
27 Oct - 28 Oct
includes taxes & fees
Stay at this luxury hotel in San Antonio. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff and the clean rooms in ...
Drury Plaza Hotel San Antonio Riverwalk
105 S Saint Marys Street San Antonio TX
The price is AU$217 per night from 8 Nov to 9 Nov
AU$217
8 Nov - 9 Nov
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and 2 hot tubs. Our guests praise the breakfast and the pool in their reviews. ...
9.4/10 Exceptional! (5,406 reviews)
"I liked the breakfast and dinner snacks. The room was clean and the beds were comfortable. Access to the River walk was easy. The elevators were the dirtiest part of the building. Really the biggest criticism was the parking sitaution. I was shocked that it was valet only and the valet service was ..."
Reviewed on 21 Oct 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Check Medical Center District hotel availability
Our guide on where to stay in Medical Center District
Find the best Medical Center District areas for the activities you enjoy most.
Downtown San Antonio
A scenic riverfront great entertainment and top sights from Alamo to Alamodome – discover Downtown San Antonio, a destination also famous for its historic sites.
Far West Side
While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.
Uptown Central
If you're spending some time in Uptown Central, Marion Koogler McNay Art Museum and Alamo Quarry Market are top sights worth seeing.
Northwest Side
If you're spending some time in Northwest Side, Huebner Oaks and Crystal Ice Palace are top sights worth seeing.
Stone Oak
Stone Oak is known for its abundant dining options, and you can plan a trip to Shops at Hardy Oak and Alta Vista at Stone Oak while you're in town.
