Hotel Sant' Anna offers a tranquil escape near Vatican Museums and St. Peter's Basilica. Guests love the serene garden, in-room WiFi, and practical amenities like luggage storage. The 24-hour front desk staff consistently earns praise for their helpful service.
Reviews
9.69.6 out of 10
Exceptional
Popular amenities
Free Wi-Fi
Air-conditioning
Housekeeping
24/7 front desk
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Located in Rome City Centre, a neighbourhood in Rome, Hotel Sant' Anna is near a metro station. St. Peter's Basilica and Vatican Museums are notable landmarks, and travellers looking to shop may want to visit Via del Corso and Via Veneto. Looking to enjoy an event or a game? See what's going on at Foro Italico or Stadio Olimpico. Visit our Rome travel guide
via borgo pio 134, Rome, RM, 193
What's nearby
St. Peter's Square
2 min walk - 0.2 km
Via Cola di Rienzo
3 min walk - 0.3 km
Castel Sant'Angelo
7 min walk - 0.6 km
St. Peter's Basilica
7 min walk - 0.6 km
Vatican Museums
8 min walk - 0.7 km
Getting around
Risorgimento/S. Pietro Tram Stop
4 min walk
Rome San Pietro Station
15 min walk
Ciampino Airport (CIA)
54 min drive
Restaurants
McDonald's
1 min walk
Pastasciutta
2 min walk
Cafe Leonina
2 min walk
Ristorante Pizzeria Marcantonio
1 min walk
Bar Moretto
2 min walk
About this property
Hotel Sant' Anna
Hotel near Sistine Chapel
A short walk from St. Peter's Basilica and Vatican Museums, Hotel Sant' Anna provides a garden and more. Guests can connect to free in-room WiFi.
Other perks at this hotel include:
Buffet breakfast (surcharge), concierge services and luggage storage
A 24-hour front desk and smoke-free property
Guest reviews give top marks for the helpful staff and location
Room features
All guest rooms at Hotel Sant' Anna include comforts, such as air conditioning, in addition to amenities, such as free WiFi and safes.
More amenities include:
Bidets, free toiletries and hairdryers
Wardrobes/cupboards, electric kettles and daily housekeeping
Daily buffet breakfast available 7:00 AM to 10:00 AM for a fee: EUR 15 per person
Conveniences
24-hour front desk
Luggage storage
Guest services
Concierge services
Housekeeping (daily)
Outdoors
Garden
Accessibility
Hardwood flooring in room
No lift
More
Smoke-free property
Room amenities
Bedroom
Bedsheets provided
Blackout drapes
Hypo-allergenic bedding
Bathroom
Bidet
Free toiletries
Hair dryer
Shampoo
Soap
Toilet paper
Towels provided
Entertainment
Flat-screen TV
Food and drink
Coffee/tea maker
Electric kettle
Minibar
More
Air conditioning (climate-controlled)
Desk
Free local calls
Phone
Safe
Policies
Check-in
Check-in start time: 1 PM; check-in end time: midnight
Late check-in subject to availability
Minimum check-in age - 18
Check-out
Check-out before 10:30 AM
Special check-in instructions
Front desk staff will greet guests on arrival at the property
If you are planning to arrive after midnight please contact the property in advance using the information on the booking confirmation
For any questions, please contact the property using the information on the booking confirmation
Information provided by the property may be translated using automated translation tools
Guests staying at the apartments should go the hotel's main address to check in.
Renovations and closures
The property is closed between 11 August and 22 August.
Access methods
Staffed front desk
Pets
Pets not allowed
Children and extra beds
Children are welcome
Rollaway/extra beds are not available.
Payment types
Important information
Fees
You'll be asked to pay the following charges at the property. Fees may include applicable taxes:
A tax is imposed by the city: EUR 6.00 per person, per night, up to 10 nights. This tax does not apply to children under 10 years of age.
We have included all charges provided to us by the property.
Optional extras
Fee for buffet breakfast: from approximately EUR 15 per person
The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.
You need to know
Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards, debit cards and cash
Safety features at this property include a carbon monoxide detector, a fire extinguisher and a smoke detector
Please note that cultural norms and guest policies may differ by country and by property; the policies listed are provided by the property
Property Registration Number IT058091A1AJXSQ7XJ
We should mention
This property does not have any lifts
All guests, including children, must be present at check-in and show their government-issued photo ID card or passport
Cash transactions at this property cannot exceed EUR 5000, due to national regulations; for further details, please contact the property using the information in the booking confirmation
Only registered guests are allowed in the guestrooms
National rating
This property has received its official star rating from the local rating authority.
Property is also known as
Hotel Sant' Anna Rome
Hotel Sant' Anna
Sant' Anna Rome
Sant Anna Rome
Sant Anna Hotel Rome
Hotel Sant' Anna Rome
Hotel Sant' Anna Hotel
Hotel Sant' Anna Hotel Rome
Frequently asked questions
Is Hotel Sant' Anna pet-friendly?
No, pets are not allowed at this property.
How much is parking at Hotel Sant' Anna?
This property doesn't offer parking.
What time is check-in at Hotel Sant' Anna?
Check-in start time: 1 PM; check-in end time: midnight. Late check-in is available during limited hours.
What time is check-out at Hotel Sant' Anna?
Checkout is at 10:30 AM.
Where is Hotel Sant' Anna located?
Located in Rome City Centre, this hotel is within a 10-minute walk of St. Peter's Square, St. Peter's Basilica and Sistine Chapel. Vatican Museums and Castel Sant'Angelo are also within 15 minutes. Risorgimento/S. Pietro Tram Stop is only a 4-minute walk and Ottaviano - San Pietro - Musei Vaticani Station is 9 minutes.
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Reviews
Hotel Sant' Anna Reviews
9.6
Exceptional
All reviews shown are from real guest experiences. Only travellers who have booked a stay with us can submit a review. We verify reviews according to our guidelines and publish all reviews, positive or negative.More informationOpens in a new window
9.8
Cleanliness
9.4
Location
9.8
Staff & service
9.4
Property conditions & facilities
Rating 10 - Excellent. 262 out of 326 reviews
10 - Excellent
262
Rating 8 - Good. 49 out of 326 reviews
8 - Good
49
Rating 6 - Okay. 11 out of 326 reviews
6 - Okay
11
Rating 4 - Poor. 3 out of 326 reviews
4 - Poor
3
Rating 2 - Terrible. 1 out of 326 reviews
2 - Terrible
1
Reviews
10/10 Excellent
John
6 Nov 2025
Liked: Cleanliness, staff & service, amenities
Rooms were immaculate, staff were courteous, breakfast was wonderful.
This hotel is very quaint near everything to walk. The front desk was very nice and helpful and polite. Nice breakfast in the morning too. I would definitely stay here again.
Extremely nice and helpful staff. Room was very quaint and great access to a lot of tourist spots within a mile. Room was cleaned every day. Highly recommend
It is a small, very neat hotel in a quiet environment at night, close to the Vatican. There are many small restaurants and cafes nearby, so we did not have trouble finding a meal.
The facilities are good, staff amazing, the location is unbeatable if you are looking to stay near the Vatican. The Breakfast is okay. In others words, highly recomended hotel.
Wonderful stay in a fabulous location! Welcoming and friendly staff were most accommodating and helpful with our needs and questions. Well-appointed rooms. Delicious buffet breakfast. Great restaurant and gelato vendor on either side of the lovely entrance. We can’t wait to return for a repeat stay!