Search Panama City hotels

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
10 Dec - 11 Dec
Tomorrow
11 Dec - 12 Dec
This weekend
12 Dec - 14 Dec
Next weekend
19 Dec - 21 Dec

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Panama City hotels

Outdoor pool, pool loungers
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (4651)
"Very clean hotel and hotel rooms were also very clean."
United States
Betty
Travelling for leisure
The price is AU$203
includes taxes & fees
15 Dec - 16 Dec
Hotel Riu Plaza Panama
Front of property
Megapolis Hotel Panamá

Megapolis Hotel Panamá

Megapolis Hotel Panamá
4.5 star property
San Francisco
8.4 out of 10, Very good, (1261)
"The rooms very clean & the food good as well too."
United States
Eric
Travelling solo
The price is AU$217
includes taxes & fees
11 Dec - 12 Dec
Megapolis Hotel Panamá
Front of property
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo
4.0 star property
Casco Viejo
9.0 out of 10, Wonderful, (1001)
"Love the location and the restaurant inside the hotel was phenomenal."
United States
Jennifer
Travelling with small children
The price is AU$331
includes taxes & fees
11 Dec - 12 Dec
Central Hotel Panama Casco Viejo
Front of property – evening/night
Principe Hotel and Suites

Principe Hotel and Suites

Principe Hotel and Suites
3.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1590)
"Excellent Hotel very spacious room and conveniently centered,"
United States
JULIAN
The price is AU$83
includes taxes & fees
27 Dec - 28 Dec
Principe Hotel and Suites
Daily buffet breakfast (PAB 10 per person)
Hospedium Princess Hotel Panama

Hospedium Princess Hotel Panama

Hospedium Princess Hotel Panama
3.5 star property
Bella Vista
7.6 out of 10, Good, (693)
"the room was very big and spacious. could do with some newer furniture"
United States
Sadé
Travelling with partner
The price is AU$85
includes taxes & fees
5 Jan - 6 Jan 2026
Hospedium Princess Hotel Panama
50-inch LED TV with satellite channels
Arcadia Condo Suites

Arcadia Condo Suites

Arcadia Condo Suites
2.5 star property
Costa del Este
9.4 out of 10, Exceptional, (157)
"Clean space, lots of parking, fast internet, nice rooftop with pool."
United States
Joseph
Travelling for leisure and business
The price is AU$179
includes taxes & fees
15 Dec - 16 Dec
Arcadia Condo Suites
Lobby
Hyatt Regency Panama City

Hyatt Regency Panama City

Hyatt Regency Panama City
4.5 star property
Bella Vista
10.0 out of 10, Exceptional, (121)
"Staff availability and helpfulness, customer service, decor, cleanliness and gym makes this choice a great one."
United States
Shakira
Travelling with partner
The price is AU$224
includes taxes & fees
13 Dec - 14 Dec
Hyatt Regency Panama City
View from property
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

Las Americas Golden Tower Panama
4.0 star property
San Francisco
9.0 out of 10, Wonderful, (1009)
"Rooms were clean and well kept"
United States
Lesandy
Travelling with friends
The price is AU$269
includes taxes & fees
10 Jan - 11 Jan 2026
Las Americas Golden Tower Panama
Terrace/patio
Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
San Francisco
9.4 out of 10, Exceptional, (2138)
"The room was clean and spacious."
United States
Sandra
Travelling with family
The price is AU$179
includes taxes & fees
2 Jan - 3 Jan 2026
Plaza Paitilla Inn Hotel
Lobby sitting area
Hotel Coral Suites

Hotel Coral Suites

Hotel Coral Suites
3.5 star property
Bella Vista
9.0 out of 10, Wonderful, (1005)
"Great location with spacious rooms"
United States
Paul
Travelling solo
The price is AU$110
includes taxes & fees
4 Jan - 5 Jan 2026
Hotel Coral Suites
4 outdoor pools, free pool cabanas, pool umbrellas
JW Marriott Panama

JW Marriott Panama

JW Marriott Panama
5.0 star property
San Francisco
9.0 out of 10, Wonderful, (1007)
"The pool area is amazing"
United States
Stephen
Travelling for leisure
The price is AU$462
includes taxes & fees
14 Dec - 15 Dec
JW Marriott Panama
Exterior
Novotel Panama City

Novotel Panama City

Novotel Panama City
4.0 star property
Bella Vista
9.2 out of 10, Wonderful, (1017)
"The room was spacious and very clean."
United States
Leo
Travelling for leisure
The price is AU$176
includes taxes & fees
13 Dec - 14 Dec
Novotel Panama City
Reception
MARINN Tropical Vibes Hotel

MARINN Tropical Vibes Hotel

MARINN Tropical Vibes Hotel
3.5 star property
Amador
8.2 out of 10, Very good, (183)
"Rooms were clean, spacious and had a great view of the ocean / marina."
United States
Rajiv Sachin
The price is AU$102
includes taxes & fees
11 Dec - 12 Dec
MARINN Tropical Vibes Hotel
Front of property
Decapolis Hotel Panama City

Decapolis Hotel Panama City

Decapolis Hotel Panama City
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1436)
"Clean room, staff was friendly and helpful."
United States
Carol
Travelling with partner
The price is AU$185
includes taxes & fees
11 Dec - 12 Dec
Decapolis Hotel Panama City
View from property
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz
9.6 out of 10, Exceptional, (636)
"The room features were excellent—comfortable, beautifully designed, and equipped with everything we needed for a relaxing stay."
Canada
Carla
Travelling for leisure
The price is AU$384
includes taxes & fees
12 Dec - 13 Dec
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Outdoor pool, open 7:00 AM to 8:00 PM, pool umbrellas
Marriott Panama Hotel

Marriott Panama Hotel

Marriott Panama Hotel
4.0 star property
Panama City
9.0 out of 10, Wonderful, (1002)
"Rooms were very spacious and clean."
United States
Arianna
Travelling for leisure
The price is AU$235
includes taxes & fees
12 Dec - 13 Dec
Marriott Panama Hotel
Couples treatment room(s), sauna, steam room, body treatments
Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel
5.0 star property
Bella Vista
9.4 out of 10, Exceptional, (1000)
"A lovely hotel and excellent food and rooms and service."
United States
Allison
The price is AU$327
includes taxes & fees
9 Jan - 10 Jan 2026
Bristol Panama, a Registry Collection Hotel
2 restaurants, local cuisine
W Panama

W Panama

W Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1000)
"The hotel was very clean and comfortable."
United States
Ginay
Travelling with partner
The price is AU$343
includes taxes & fees
20 Dec - 21 Dec
W Panama
Exterior
Aloft Panama

Aloft Panama

Aloft Panama
3.5 star property
San Francisco
8.8 out of 10, Excellent, (891)
"Location, large rooms, many on site dinning options, free parking, amazing interior design."
United States
Rodolfo
Travelling with family
The price is AU$194
includes taxes & fees
16 Dec - 17 Dec
Aloft Panama
Exterior
TRYP by Wyndham Panamá Centro

TRYP by Wyndham Panamá Centro

TRYP by Wyndham Panamá Centro
3.5 star property
Bella Vista
9.2 out of 10, Wonderful, (1007)
"Great location, friendly staff, clean room along with a good place to grab a drink and dinner."
United States
Michelle
Travelling for leisure
The price is AU$151
includes taxes & fees
17 Dec - 18 Dec
TRYP by Wyndham Panamá Centro
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Holiday Rentals in Panama City

Aparthotel
50-inch LED TV with satellite channels
Arcadia Condo Suites

Arcadia Condo Suites

Arcadia Condo Suites
2.5 star property
Costa del Este
9.4 out of 10, Exceptional, (157)
"Everything was great, helpful staff, great room , clean, excellent service!"
Arcadia Condo Suites
See all holiday rentals
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Our guide on where to stay in Panama City

Find the best Panama City areas for the activities you enjoy most. Learn more about Panama City
Learn more about Panama City

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. You might spend time checking out top sights like Via Espana and Crown Casino.

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Luxor Towers might round out your trip.

San Francisco

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

Punta Paitilla

Punta Paitilla is known for its abundant dining options, and you can plan a trip to Avenida Balboa and Multicentro Panama while you're in town.

Stay near popular Panama City attractions

You can find Gucci at Luxury Avenue at Multiplaza Mall in Panama City. #LuxuryShopping #LifeatExpedia #PanamaCity
Photo by Fabiola Tile
Open Photo by Fabiola Tile

Multiplaza Pacific Mall

4.4/5 (1,590 reviews)
Panama's premier shopping destination houses over 500 stores, from luxury brands like Gucci to popular retailers like Apple. Obtain the Panama Shopping Card at reception for exclusive discounts throughout the mall.
See properties
Causeway, Amador, Panama

Amador Causeway

4.4/5 (1,305 reviews)
This man-made causeway connects Panama City to four islands using excavated material from the Panama Canal. Rent a bicycle to explore its entire length, stopping for waterfront dining with skyline views.
See properties

Learn more about Panama City

The gleaming skyscrapers of this cosmopolitan capital stand in striking contrast to the colonial charm of Casco Viejo. Watch massive ships navigate the Canal locks, then sample ceviche at the seafood market where local fishermen bring their daily catch.

See all hotels in Panama City
Panoramic view at the Downtown of Panama City - Panama

Top Panama City Hotel Reviews

Recent Reviews in Panama City

Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino

10/10 Excellent
"Everything was great about this hotel, to the point I didn’t want to get out of bed and do my activities for the day 😂. Room was clean, fresh breakfast everyday, full sized shampoo, conditioner and body wash available for us, meaning, I didn’t have to bring anything with me. I’ll definitely recommend it for both solo travelers and families."
Nicol 6-night trip
Posted 2 days ago
Waymore Hotel Spa & Casino

More cheap accommodation in Panama City

Viajero Casco Viejo Hostel

Viajero Casco Viejo Hostel

Avenida B, Calle 12 Este, Casco Viejo Panama City
The price is AU$121 per night from 17 Dec to 18 Dec
AU$121
17 Dec - 18 Dec
includes taxes & fees
7/10 Good! (10 reviews)

Frequently asked questions

What's the best place to stay in Panama City?
Hyatt Regency Panama City is a favourite property for Expedia customers. This hotel is a short 4-minute walk from Via Espana, and it offers a full-service spa and 2 bars. Reviews from our site also recommend Sofitel Legend Casco Viejo, Panama City and Hotel La Compañía Casco Antiguo as top options for your stay. See all available top hotels, or vacation rentals in Panama City.
What are some of the best holiday rentals that Panama City has to offer?
Panama View House – A Hilltop Retreat with Stunning Canal Views: This highly rated holiday home rental in Panama City has air conditioning and laundry facilities to help you feel perfectly comfortable in your new surroundings. Some other homes for rent in Panama City include Tropical House with Historic Charm, WiFi, Private Bathrooms and Workspaces and Oasis with pool near panama canal. See all vacation rentals in Panama City.
If I need to cancel my hotel reservation in Panama City, will I receive a refund?
Yes, most hotel reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your check-in date. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Panama City.
What's the best budget-friendly hotel in Panama City?
Based on reviews, Hotel Riu Plaza Panama is a popular hotel for our travellers who want a more economical choice, and features free buffet breakfast and free Wi-Fi. Other choices to stay on the cheap include Plaza Paitilla Inn Hotel and The Executive Hotel. View all budget hotels in Panama City.
What's the best family accommodation in Panama City?
W Panama is a hotel with an outdoor pool and 2 restaurants, and it's a top choice on Expedia for families. Other good choices to stay with the children include JW Marriott Panama and Marriott Panama Hotel. Also, attractions such as Biomuseo and Summit Botanical Gardens & Zoo are fun for children of all ages. Find more child-friendly accommodations in Panama City.
What is the favourite LGBTQ-friendly place to stay in Panama City?
Hotel Riu Plaza Panama is a top LGBTQ-friendly hotel, and features 3 restaurants and free WiFi. JW Marriott Panama and AC Hotel by Marriott Panama City are two other good options for your holiday. See all available hotels listed as LGBTQ-friendly in Panama City.
What's the best dog-friendly accommodation option in Panama City?
W Panama is a top hotel for people travelling with their pets, and offers 2 restaurants and iPod docks for its human guests. Other good options for you and your pet include JW Marriott Panama and Marriott Panama Hotel. See more pet-friendly hotel accommodations in Panama City.
What's the best accommodation option for a beach holiday in Panama City?
Akwadup Lodge is a top beachfront lodge with a restaurant, and it's located close to Veracruz Beach . See more stays near the beach in Panama City.
What's the best luxury accommodation option in Panama City?
Hotel Riu Plaza Panama is a luxury hotel with 3 restaurants and valet parking, and it's a popular choice for Expedia travellers looking for an elegant place to stay. Megapolis Hotel Panamá and W Panama are two other upscale options for your trip. Find more luxury hotels in Panama City.
What's the best boutique-style accommodation in Panama City?
De Ville Hotel is a favourite hotel with our travellers looking for stylish accommodation, and features 33 guestrooms, free breakfast and free valet parking. If you want to stay at a boutique hotel, also consider Gatto Blanco Party Hotel. See all boutique hotels in Panama City.
What's the best hotel for some casino gaming in Panama City?
Megapolis Hotel Panamá is a top hotel featuring a casino and free stocked minibars. Other good options to try your luck include Renaissance Panama City Hotel and Decapolis Hotel Panama City. See more casino hotels in Panama City.
What are some accommodation options with pools in Panama City?
JW Marriott Panama is a top hotel with 4 outdoor swimming pools, a children's pool and 3 restaurants. A couple of other options that offer an on-site pool include Marriott Panama Hotel and Las Americas Golden Tower Panama. View all hotels with pools in Panama City.
What is the best spa hotel in Panama City?
Megapolis Hotel Panamá is a top luxury spa hotel featuring 3 bars, a casino, a shopping centre and a rooftop terrace. Enjoy a facial, body scrub or detox wrap at the on-site spa. Other popular spa hotels in Panama City include W Panama and Las Americas Golden Tower Panama. See all spa hotels in Panama City.
What's it like staying in Panama City?
Travellers to Panama City give high marks for the shopping, casinos and top-notch restaurants. Tourists who journey to this scenic city can discover its cafes, bars and local tours. A top sight in the city is Albrook Shopping Mall. In Panama City, there are 1405 hotels and other accommodation options to choose from. Find out more about Panama City.
What should I see while I'm in Panama City?
Cultural venues include National Theater, Interoceanic Canal Museum and Mi Pueblito. Attractions like Biomuseo and Summit Botanical Gardens & Zoo are fun for everyone. Landmarks like Iglesia del Carmen, Calle 50 and Panama Canal Railway might be worth a visit. Take a look at what more there is to see and do in Expedia's Panama City guide.
How can I get around Panama City?
Walk to nearby metro stations such as Iglesia del Carmen Station, Vía Argentina and Santo Tomas Station. To see more of the larger area, take a train from Panama City Passenger Station. If you want to venture out around the area, you may want a rental car in Panama City for your journey.
What's the seasonal weather in Panama City?
The hottest months are usually March and April, with an average temperature of 27°C, while the coldest months are January and February, with an average of 26°C. The rainiest months in Panama City are July, August, June and November, with each month seeing an average of 369 mm of rainfall.

Explore a world of travel with Expedia