Luxury Hotels & Resorts in Panama City from AU$225

Start date: Check-in selected.
End date: Check-out
    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check availability on Panama City Luxury Hotels

Best Panama City Luxury Hotels

Our top choices for Panama City luxury hotels

JW Marriott Panama

5.0 star property
8.8 out of 10, Excellent, (1012)
"Hotel staff and service was pleasant and professional."
The price is AU$412
includes taxes & fees
3 Oct - 4 Oct
JW Marriott Panama

Bristol Panama, a Registry Collection Hotel

5.0 star property
9.2 out of 10, Wonderful, (1003)
"A lovely hotel and excellent food and rooms and service. "
The price is AU$336
includes taxes & fees
3 Oct - 4 Oct
Bristol Panama, a Registry Collection Hotel

Waldorf Astoria Panama

5.0 star property
9.0 out of 10, Wonderful, (1005)
"Great hotel for my recent stay in Panam "
The price is AU$369
includes taxes & fees
20 Sept - 21 Sept
Waldorf Astoria Panama

American Trade Hotel

4.5 star property
9.4 out of 10, Exceptional, (555)
"Great hotel in Oldtown Panama City"
The price is AU$429
includes taxes & fees
9 Sept - 10 Sept
American Trade Hotel

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

4.5 star property
8.8 out of 10, Excellent, (987)
"2nd stay at Sortis Hotel in Panama. Never disappoints. Breakfast Buffett incredible and staff pleasant and attentive! Will stay there again!"
The price is AU$252
includes taxes & fees
3 Sept - 4 Sept
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

Hilton Panama

5.0 star property
8.8 out of 10, Excellent, (1007)
"The food was very good at the hotel. Several options to choose from at the hotel. "
The price is AU$384
includes taxes & fees
27 Sept - 28 Sept
Hilton Panama

Megapolis Hotel Panamá

5.0 star property
8.4 out of 10, Very good, (1001)
"This is THE place to stay in Panama City... it's location, friendly accommodating staff, and the amenities are fantastic. The rooms were wonderful, clean and bright. We tried Tauro (steakhouse) and the Bazaar - they were both delicious and the service excellent. We literally partied like rock stars at their rooftop restaurant, and at the wonderful outdoor infinity pool as well. We will definitely be returning! "
Megapolis Hotel Panamá

Manrey Boutique Hotel

3.5 star property
7.6 out of 10, Good, (255)
Manrey Boutique Hotel

Las Americas Golden Tower Panama

4.0 star property
8.8 out of 10, Excellent, (1009)
"Great staff and accommodations "
The price is AU$269
includes taxes & fees
6 Sept - 7 Sept
Las Americas Golden Tower Panama

Marriott Panama Hotel

4.0 star property
9.0 out of 10, Wonderful, (1007)
"Had an amazing stay with my family "
The price is AU$225
includes taxes & fees
6 Sept - 7 Sept
Marriott Panama Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find out more about Panama City

Find out more about Panama City

Panama Cityand its attractions for luxury travelers

Panama City offers an exquisite blend of modern luxury and rich cultural heritage, perfect for discerning travellers. Start your journey at the iconic Panama Canal, where you can witness the engineering marvel up close with a guided tour, or opt for a luxurious yacht cruise to truly appreciate its grandeur from the water. The historic Casco Viejo district enchants with its cobbled streets and historic architecture, where you can indulge in gourmet dining at world-class restaurants like Casa Casco, known for its rooftop views and innovative cuisine. For art aficionados, the Biomuseo, designed by Frank Gehry, showcases Panama's biodiversity and is a stunning site in itself. Don't miss a visit to the Amador Causeway, a scenic promenade lined with upscale cafés and shops, offering breathtaking views of the city skyline and the Pacific Ocean. For a luxurious stay, the vibrant neighbourhood of Punta Pacifica is a prime location, home to high-end hotels like the JW Marriott, which boasts stunning ocean views, lavish spas, and exceptional dining options. Here, you can enjoy the convenience of being close to both the city’s business district and beautiful beaches, making it easy to unwind after a day of exploration.

Find the best luxury hotels and resorts in Panama City

For those seeking a lavish escape in Panama City, these top hotels offer an exquisite blend of comfort and elegance, ensuring an unforgettable stay.

Ramada Plaza By Wyndham Panama Punta Pacífica

  • Why it's great for a luxury retreat: Recognised for its outstanding traveler review rating of 9.6, Ramada Plaza By Wyndham Panama Punta Pacífica is a luxurious retreat that guarantees a memorable stay. The hotel offers an elegant Beaux Arts hotel design, alongside premium bedding and concierge services that elevate every aspect of the experience. Guests can savour fine dining with couples dining options and enjoy champagne service for a truly lavish experience.
  • Other amenities: The hotel also features an outdoor pool for relaxation, a well-appointed fitness centre open 24 hours, and a buffet breakfast service. Additional highlights include a minibar in each room, a shopping mall onsite, and the convenience of early check-in and late check-out. With a stunning terrace and nearby ocean access, travelers can fully immerse themselves in the luxury that this hotel offers.
  • Neighborhood: San Francisco
  • Nearby attractions: Calle 50 - 0.7 km, Multiplaza Pacific Mall - 0.3 km, ATLAPA Conventions Center - 1 km

Plaza Paitilla Inn Hotel

  • Why it's great for a luxury retreat: With an exceptional traveler review rating of 9.4, Plaza Paitilla Inn Hotel provides a luxurious experience that is both welcoming and relaxing. This upscale hotel features premium bedding and a secured valet parking service, ensuring that travelers feel pampered from the moment they arrive. The outdoor pool area is perfect for unwinding, while the hotel's spa offers a range of treatments for an indulgent experience.
  • Other amenities: Guests can enjoy a complimentary buffet breakfast each morning, along with an array of spa services including reflexology and Swedish massages. The hotel also features a terrace for relaxation, and various shopping options onsite for those looking to indulge during their stay. Fitness facilities and pool umbrellas add to the comfort, making this hotel a splendid spot for luxury seekers.
  • Neighborhood: Punta Paitilla
  • Nearby attractions: Avenida Balboa - 0.5 km, Cinta Costera - 0.8 km, Multicentro Panama - 1.4 km

Bristol Panama, a Registry Collection Hotel

  • Why it's great for a luxury retreat: Bristol Panama stands out with its remarkable traveler review rating of 9.2, showcasing an exquisite blend of luxury and sophistication. This hotel features an onsite art gallery, providing a unique cultural experience for travelers. The luxurious amenities include designer toiletries, bathrobes, and premium bedding, ensuring a restful and opulent stay. Valet parking and concierge services further enhance the level of service offered to travelers.
  • Other amenities: Additional features include a 24-hour room service, a spa complete with steam rooms and treatment areas, and an outdoor pool for relaxation. Guests can also enjoy a terrace, fitness facilities, and various dining options, including couples dining. The hotel’s strategic location in Bella Vista offers easy access to local attractions, making it a top choice for luxury travellers.
  • Neighborhood: Bella Vista
  • Nearby attractions: Uruguay Street - 0.6 km, Calle 50 - 0.7 km, Avenida Balboa - 0.7 km

The Executive Hotel

  • Why it's great for a luxury retreat: The Executive Hotel is a splendid choice for luxury seekers, with an excellent traveler review rating of 9.2. Guests can experience premium bedding and top concierge services that enhance their stay. The hotel’s location in the vibrant Bella Vista neighbourhood offers easy access to shopping districts, making it a convenient spot for travelers looking to indulge in some retail therapy.
  • Other amenities: The hotel also provides a delightful buffet breakfast each morning, an outdoor pool with sun loungers, and complimentary airport transportation. Additional services include self-parking and an area shuttle, ensuring convenience for all travellers. With daily housekeeping and toiletries provided for free, every detail has been carefully considered to ensure a luxurious experience.
  • Neighborhood: Bella Vista
  • Nearby attractions: Uruguay Street - 0.6 km, Calle 50 - 0.7 km, Avenida Balboa - 0.8 km

Hotel Riu Plaza Panama

  • Why it's great for a luxury retreat: Hotel Riu Plaza Panama is a pinnacle of luxury, featuring an impressive traveler review rating of 9.0. This hotel offers an array of upscale amenities, including a Club Level Room with exclusive lounge access, valet parking, and a refreshing outdoor pool complemented by a poolside bar. Guests can indulge in the convenience of concierge services and enjoy the vibrant shopping district right at their doorstep.
  • Other amenities: Alongside its luxurious offerings, the hotel boasts a serene spa with treatment rooms, a well-equipped fitness centre, and complimentary buffet breakfast. Guests can also take advantage of the air-conditioned rooms featuring minibars and daily housekeeping, ensuring a comfortable and straightforward stay. With additional services like self-parking and covered valet parking, every aspect of the visit is catered for, making it a top choice for discerning travellers.
  • Neighborhood: Bella Vista
  • Nearby attractions: Uruguay Street - 1.5 km, Calle 50 - 0 km, Via Espana - 1 km

Popular luxurious hotels

Most upscale stays in Panama City in 2025

Top Panama City Hotel Reviews

Explore a world of travel with Expedia

Explore a world of travel with Expedia