Cheap Flights from Panama City (PTY) to Mexico City (MEX)

View AU$268 flight on Thu, 25 Dec 2025Opens in a new window

Popular airlines from Tocumen Intl. Airport (PTY) to Benito Juarez International Airport (MEX)

  • Plan, book, fly with confidence

  • trending down icon

    Be in the know

    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon

    Book smarter

    Save up to 35% on select hotels after you book a flight*
  • payments icon

    Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Cheap Flights from Panama City (PTY) to Mexico City (MEX)

Prices were available within the past 7 days for one-way flights and round trip tickets for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Sat, 13 Dec - Mon, 15 Dec
PTY
Panama City
MEX
Mexico City
AU$882 Return, found 2 days ago
AU$882
Return
found 2 days ago
Select Copa flight, departing Sat, 13 Dec from Panama City to Mexico City, returning Mon, 15 Dec, priced at AU$882 found 2 days ago
avianca
Sat, 13 Dec - Mon, 15 Dec
PTY
Panama City
MEX
Mexico City
AU$1,053 Return, found 2 days ago
AU$1,053
Return
found 2 days ago
Select avianca flight, departing Sat, 13 Dec from Panama City to Mexico City, returning Mon, 15 Dec, priced at AU$1,053 found 2 days ago
avianca
Sat, 13 Dec - Mon, 15 Dec
PTY
Panama City
MEX
Mexico City
AU$1,055 Return, found 2 days ago
AU$1,055
Return
found 2 days ago
Select avianca flight, departing Sat, 13 Dec from Panama City to Mexico City, returning Mon, 15 Dec, priced at AU$1,055 found 2 days ago
avianca
Sat, 13 Dec - Mon, 15 Dec
PTY
Panama City
MEX
Mexico City
AU$1,065 Return, found 2 days ago
AU$1,065
Return
found 2 days ago
Select avianca flight, departing Sat, 13 Dec from Panama City to Mexico City, returning Mon, 15 Dec, priced at AU$1,065 found 2 days ago
avianca
Sat, 13 Dec - Mon, 15 Dec
PTY
Panama City
MEX
Mexico City
AU$1,071 Return, found 2 days ago
AU$1,071
Return
found 2 days ago
Select avianca flight, departing Sat, 13 Dec from Panama City to Mexico City, returning Mon, 15 Dec, priced at AU$1,071 found 2 days ago
avianca
Sat, 13 Dec - Mon, 15 Dec
PTY
Panama City
MEX
Mexico City
AU$1,081 Return, found 2 days ago
AU$1,081
Return
found 2 days ago
Select avianca flight, departing Sat, 13 Dec from Panama City to Mexico City, returning Mon, 15 Dec, priced at AU$1,081 found 2 days ago
avianca
Sat, 13 Dec - Mon, 15 Dec
PTY
Panama City
MEX
Mexico City
AU$1,088 Return, found 2 days ago
AU$1,088
Return
found 2 days ago
Select avianca flight, departing Sat, 13 Dec from Panama City to Mexico City, returning Mon, 15 Dec, priced at AU$1,088 found 2 days ago
avianca
Sat, 13 Dec - Mon, 15 Dec
PTY
Panama City
MEX
Mexico City
AU$1,126 Return, found 2 days ago
AU$1,126
Return
found 2 days ago
Select avianca flight, departing Sat, 13 Dec from Panama City to Mexico City, returning Mon, 15 Dec, priced at AU$1,126 found 2 days ago
Aeromexico
Sat, 13 Dec - Mon, 15 Dec
PTY
Panama City
MEX
Mexico City
AU$1,264 Return, found 2 days ago
AU$1,264
Return
found 2 days ago
Select Aeromexico flight, departing Sat, 13 Dec from Panama City to Mexico City, returning Mon, 15 Dec, priced at AU$1,264 found 2 days ago
United
Sat, 13 Dec - Mon, 15 Dec
PTY
Panama City
MEX
Mexico City
AU$2,015 Return, found 2 days ago
AU$2,015
Return
found 2 days ago
Select United flight, departing Sat, 13 Dec from Panama City to Mexico City, returning Mon, 15 Dec, priced at AU$2,015 found 2 days ago

Find the cheapest month to fly from Panama City (PTY) to Mexico City (MEX)

July is typically the cheapest month to fly

From AU$370 - AU$825 per traveller.

Graph displaying average flight prices per month

Flight from Panama City to Mexico City route information
Origin airport
Tocumen Intl.
Destination airport
Mexico City Intl.
Return price
AU$882
Distance
2397 km
Average flight time
2 hours 46 mins

Your quick guide to flights from Panama City to Mexico City

Pick up great flights from Panama City to Mexico City

With Expedia, you have your pick of 9 flights a day with 20 airlines covering flights from Panama City to Mexico City. Whether you’re on a business trip, a family holiday or a luxury break, just enter your travel dates, hit search then check out your choice of flights. Select from return, one way or multi-city flights, and use the advance search tool if you want a direct or refundable flight. You can narrow your search to show you just your preferred cabin class and airline, too. It’s all easy. You can book direct flights from Panama City to Mexico City that take around 2 hours.

Find cheap flights from Panama City to Mexico City

From the great flight deals with prices currently ranging from AU$882 to AU$2,015, you can choose to see the cheapest flights first. Generally, you can book the cheapest flights from Panama City to Mexico City around 4 to 6 weeks in advance. If your travel dates are flexible, try to avoid weekends and peak seasons – when you are more likely to grab the lowest prices. Even last minute, there are some impressive deals. The cheapest time to fly to Mexico City is normally in December.

Reasons to book your flight from Panama City to Mexico City with Expedia

Expedia makes it easy to find, book, and travel, with everything you need all in one place. When you enter your travel details, find fantastic deals just for you on flight tickets from Panama City to Mexico City across all the main airline carriers, so you can save time, dollars, and hassle finding the perfect flight. If you think your plans could change, choose refundable flights so any changes won’t cost you more. Book your flight to Mexico City right now and, if you join Expedia Rewards, you earn points this time and every time you travel with Expedia.

Frequently asked questions

How much is a flight from Panama Airport to MEX?
Within the past 7 days on Expedia, for flights departing within the next year, the lowest price available for a round-trip journey between Panama Airport and Benito Juárez Intl. Airport was AU$882. Great fares don't last forever, so make sure you book yours ASAP. Prices and availability are subject to change. Additional terms apply.
Do I need to pay a cancellation fee if I cancel my flight from Panama Airport to MEX?
When it comes to cancellation fees, each airline has its own terms and conditions. If you decide to cancel your trip, head to our Customer Service Portal.
How do I find cheap flights from Tocumen Intl. Airport (PTY) to Mexico Airport that have flexible change policies?
Many airlines offer the option to reschedule your flight without a change fee. All you pay is the difference between the original flight and the new flight. When you're searching for Panama Airport to Benito Juárez Intl. Airport flights, you'll see a "no change fees" filter for you to select.
How far is the flight from Tocumen Intl. Airport (PTY) to Mexico Airport?
Around 2 400 kilometres separates Tocumen and Mexico City, so pack some entertainment to keep you occupied for a few hours. That gripping novel you've yet to start will be perfect.
Which airlines fly direct from Panama Airport to Mexico City Intl. Airport (MEX)?
Operating 147 flights monthly, Copa Airlines (CM) is a top choice when flying straight from PTY to Mexico Airport.
Are Panama Airport to Mexico Airport flight tickets cheaper when they're purchased at the last minute?
Tickets from Tocumen Intl. Airport (PTY) to MEX are available up to a year prior to departure on Expedia. And although you may nab a fantastic last-minute deal, it's never a sure thing. Also, booking your flights well in advance means you'll have more options — and you can avoid getting caught in the dreaded middle seat! We regularly update our fares to bring you the biggest bargains, so check back often for all the latest specials.

Explore a world of travel with Expedia

*Available to Expedia members.