Cheap flights from Des Moines to Eastern Louisiana

View AU$182 flight on Sat, 6 Sep. 2025Opens in a new window

Popular airlines from Des Moines to Eastern Louisiana

  • American Airlines

    American Airlines

  • Delta

    Delta

  • United

    United

  • Plan, book, fly with confidence

  • trending down icon

    Be in the know

    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon

    Book smarter

    Save up to 35% on select hotels after you book a flight*
  • payments icon

    Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Cheap Flights from Des Moines (DSM) to Eastern Louisiana (MSY)

Prices were available within the past 7 days for one-way flights and round trip tickets for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Sat, 6 Sep. - Sat, 13 Sep.
DSM
Des Moines
MSY
New Orleans
AU$363 Return, found 20 hours ago
AU$363
Return
found 20 hours ago
Select American Airlines flight, departing Sat, 6 Sep. from Des Moines to New Orleans, returning Sat, 13 Sep., priced at AU$363 found 20 hours ago
Delta
Sat, 6 Sep. - Sat, 13 Sep.
DSM
Des Moines
MSY
New Orleans
AU$363 Return, found 20 hours ago
AU$363
Return
found 20 hours ago
Select Delta flight, departing Sat, 6 Sep. from Des Moines to New Orleans, returning Sat, 13 Sep., priced at AU$363 found 20 hours ago
American Airlines
Sat, 6 Sep. - Sat, 13 Sep.
DSM
Des Moines
MSY
New Orleans
AU$397 Return, found 20 hours ago
AU$397
Return
found 20 hours ago
Select American Airlines flight, departing Sat, 6 Sep. from Des Moines to New Orleans, returning Sat, 13 Sep., priced at AU$397 found 20 hours ago
United
Sat, 6 Sep. - Sat, 13 Sep.
DSM
Des Moines
MSY
New Orleans
AU$417 Return, found 20 hours ago
AU$417
Return
found 20 hours ago
Select United flight, departing Sat, 6 Sep. from Des Moines to New Orleans, returning Sat, 13 Sep., priced at AU$417 found 20 hours ago
Delta
Sat, 6 Sep. - Sat, 13 Sep.
DSM
Des Moines
MSY
New Orleans
AU$425 Return, found 20 hours ago
AU$425
Return
found 20 hours ago
Select Delta flight, departing Sat, 6 Sep. from Des Moines to New Orleans, returning Sat, 13 Sep., priced at AU$425 found 20 hours ago
American Airlines
Sat, 6 Sep. - Sat, 13 Sep.
DSM
Des Moines
MSY
New Orleans
AU$431 Return, found 20 hours ago
AU$431
Return
found 20 hours ago
Select American Airlines flight, departing Sat, 6 Sep. from Des Moines to New Orleans, returning Sat, 13 Sep., priced at AU$431 found 20 hours ago

Find the cheapest month to fly from Des Moines (DSM) to New Orleans (MSY)

August is typically the cheapest month to fly

From AU$262 - AU$780 per traveller.

Graph displaying average flight prices per month

*Available to Expedia members.