Cheap flights from Des Moines to Northeast Missouri

View AU$176 flight on Mon, 1 Sep. 2025Opens in a new window

Popular airlines from Des Moines to Northeast Missouri

  • Jetstar

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    Qantas Airways

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    Virgin Australia

  • Scoot

    Scoot

  • American Airlines

    American Airlines

  • Emirates

    Emirates

  • United

    United

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Cheap Flights from Des Moines (DSM) to Northeast Missouri (STL)

Prices were available within the past 7 days for one-way flights and round trip tickets for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Mon, 1 Sep. - Mon, 8 Sep.
DSM
Des Moines
STL
St. Louis
AU$304 Return, found 5 days ago
AU$304
Return
found 5 days ago
Select Delta flight, departing Mon, 1 Sep. from Des Moines to St. Louis, returning Mon, 8 Sep., priced at AU$304 found 5 days ago
Delta
Mon, 1 Sep. - Mon, 8 Sep.
DSM
Des Moines
STL
St. Louis
AU$343 Return, found 5 days ago
AU$343
Return
found 5 days ago
Select Delta flight, departing Mon, 1 Sep. from Des Moines to St. Louis, returning Mon, 8 Sep., priced at AU$343 found 5 days ago
Delta
Mon, 1 Sep. - Mon, 8 Sep.
DSM
Des Moines
STL
St. Louis
AU$351 Return, found 5 days ago
AU$351
Return
found 5 days ago
Select Delta flight, departing Mon, 1 Sep. from Des Moines to St. Louis, returning Mon, 8 Sep., priced at AU$351 found 5 days ago
American Airlines
Mon, 1 Sep. - Mon, 8 Sep.
DSM
Des Moines
STL
St. Louis
AU$366 Return, found 5 days ago
AU$366
Return
found 5 days ago
Select American Airlines flight, departing Mon, 1 Sep. from Des Moines to St. Louis, returning Mon, 8 Sep., priced at AU$366 found 5 days ago
Delta
Mon, 1 Sep. - Mon, 8 Sep.
DSM
Des Moines
STL
St. Louis
AU$388 Return, found 5 days ago
AU$388
Return
found 5 days ago
Select Delta flight, departing Mon, 1 Sep. from Des Moines to St. Louis, returning Mon, 8 Sep., priced at AU$388 found 5 days ago
United
Mon, 1 Sep. - Mon, 8 Sep.
DSM
Des Moines
STL
St. Louis
AU$449 Return, found 5 days ago
AU$449
Return
found 5 days ago
Select United flight, departing Mon, 1 Sep. from Des Moines to St. Louis, returning Mon, 8 Sep., priced at AU$449 found 5 days ago

Find the cheapest month to fly from Des Moines (DSM) to St. Louis (STL)

June is typically the cheapest month to fly

From AU$149 - AU$750 per traveller.

Graph displaying average flight prices per month

*Available to Expedia members.