Cheap flights from Des Moines to West Palm Beach

View AU$231 flight on Tue, 16 Sep. 2025Opens in a new window

Popular airlines from Des Moines to West Palm Beach

  • Plan, book, fly with confidence

  • trending down icon

    Be in the know

    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon

    Book smarter

    Save up to 35% on select hotels after you book a flight*
  • payments icon

    Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Cheap Flights from Des Moines (DSM) to West Palm Beach (PBI)

Prices were available within the past 7 days for one-way flights and round trip tickets for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Tue, 16 Sep. - Tue, 23 Sep.
DSM
Des Moines
PBI
West Palm Beach
AU$461 Return, found 16 hours ago
AU$461
Return
found 16 hours ago
Select American Airlines flight, departing Tue, 16 Sep. from Des Moines to West Palm Beach, returning Tue, 23 Sep., priced at AU$461 found 16 hours ago
Delta
Tue, 16 Sep. - Tue, 23 Sep.
DSM
Des Moines
PBI
West Palm Beach
AU$461 Return, found 16 hours ago
AU$461
Return
found 16 hours ago
Select Delta flight, departing Tue, 16 Sep. from Des Moines to West Palm Beach, returning Tue, 23 Sep., priced at AU$461 found 16 hours ago
American Airlines
Tue, 16 Sep. - Tue, 23 Sep.
DSM
Des Moines
PBI
West Palm Beach
AU$485 Return, found 16 hours ago
AU$485
Return
found 16 hours ago
Select American Airlines flight, departing Tue, 16 Sep. from Des Moines to West Palm Beach, returning Tue, 23 Sep., priced at AU$485 found 16 hours ago
United
Tue, 16 Sep. - Tue, 23 Sep.
DSM
Des Moines
PBI
West Palm Beach
AU$531 Return, found 16 hours ago
AU$531
Return
found 16 hours ago
Select United flight, departing Tue, 16 Sep. from Des Moines to West Palm Beach, returning Tue, 23 Sep., priced at AU$531 found 16 hours ago
Delta
Tue, 16 Sep. - Tue, 23 Sep.
DSM
Des Moines
PBI
West Palm Beach
AU$572 Return, found 16 hours ago
AU$572
Return
found 16 hours ago
Select Delta flight, departing Tue, 16 Sep. from Des Moines to West Palm Beach, returning Tue, 23 Sep., priced at AU$572 found 16 hours ago
Delta
Tue, 16 Sep. - Tue, 23 Sep.
DSM
Des Moines
PBI
West Palm Beach
AU$586 Return, found 16 hours ago
AU$586
Return
found 16 hours ago
Select Delta flight, departing Tue, 16 Sep. from Des Moines to West Palm Beach, returning Tue, 23 Sep., priced at AU$586 found 16 hours ago

Find the cheapest month to fly from Des Moines (DSM) to West Palm Beach (PBI)

September is typically the cheapest month to fly

From AU$343 - AU$1,001 per traveller.

Graph displaying average flight prices per month

*Available to Expedia members.