Cheap flights from Rome to South Carolina Midlands

View AU$1,134 flight on Wed, 24 Sep. 2025Opens in a new window

Popular airlines from Rome to South Carolina Midlands

  • Jetstar

    Jetstar

  • Qantas Airways

    Qantas Airways

  • Virgin Australia

    Virgin Australia

  • Scoot

    Scoot

  • American Airlines

    American Airlines

  • Emirates

    Emirates

  • United

    United

  • Plan, book, fly with confidence

  • trending down icon

    Be in the know

    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon

    Book smarter

    Save up to 35% on select hotels after you book a flight*
  • payments icon

    Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Cheap Flights from Rome (ROM) to South Carolina Midlands (CAE)

Prices were available within the past 7 days for one-way flights and round trip tickets for the period specified. Prices and availability are subject to change. Additional terms apply.

Lufthansa
Sun, 7 Sep. - Sat, 13 Sep.
FCO
Rome
CLT
Charlotte
AU$1,067 Return, found 2 days ago
AU$1,067
Return
found 2 days ago
Select Lufthansa flight, departing Sun, 7 Sep. from Rome to Charlotte, returning Sat, 13 Sep., priced at AU$1,067 found 2 days ago
United
Sun, 7 Sep. - Sat, 13 Sep.
FCO
Rome
CLT
Charlotte
AU$1,107 Return, found 2 days ago
AU$1,107
Return
found 2 days ago
Select United flight, departing Sun, 7 Sep. from Rome to Charlotte, returning Sat, 13 Sep., priced at AU$1,107 found 2 days ago
American Airlines
Sun, 7 Sep. - Sat, 13 Sep.
FCO
Rome
CLT
Charlotte
AU$1,180 Return, found 2 days ago
AU$1,180
Return
found 2 days ago
Select American Airlines flight, departing Sun, 7 Sep. from Rome to Charlotte, returning Sat, 13 Sep., priced at AU$1,180 found 2 days ago
American Airlines
Sun, 7 Sep. - Sat, 13 Sep.
FCO
Rome
CLT
Charlotte
AU$1,180 Return, found 2 days ago
AU$1,180
Return
found 2 days ago
Select American Airlines flight, departing Sun, 7 Sep. from Rome to Charlotte, returning Sat, 13 Sep., priced at AU$1,180 found 2 days ago
KLM
Sun, 7 Sep. - Sat, 13 Sep.
FCO
Rome
CLT
Charlotte
AU$1,211 Return, found 2 days ago
AU$1,211
Return
found 2 days ago
Select KLM flight, departing Sun, 7 Sep. from Rome to Charlotte, returning Sat, 13 Sep., priced at AU$1,211 found 2 days ago
Delta
Sun, 7 Sep. - Sat, 13 Sep.
FCO
Rome
CLT
Charlotte
AU$1,268 Return, found 2 days ago
AU$1,268
Return
found 2 days ago
Select Delta flight, departing Sun, 7 Sep. from Rome to Charlotte, returning Sat, 13 Sep., priced at AU$1,268 found 2 days ago
*Available to Expedia members.